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LZTS2 (NM_032429) Human Untagged Clone
CAT＃: SC305446
LZTS2 (untagged)-Human leucine zipper, putative tumor suppressor 2 (LZTS2)
CNY 4,912.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LAPSER1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_032429 edited
CTGGAGCCGAGGCGCAGGTGGCGCTGGGTTGCCTGCGAGGCCGCTGGCCAGGCCTGAGCC TCTGCCACCATGGCCATTGTGCAGACTCTGCCAGTGCCACTGGAGCCTGCTCCTGAAGCT GCCACTGCCCCACAAGCTCCAGTCATGGGTAGTGTGAGCAGCCTTATCTCAGGCCGGCCC TGTCCCGGGGGGCCAGCTCCTCCCCGCCACCACGGCCCTCCTGGGCCCACCTTCTTCCGC CAGCAGGATGGCCTGCTACGGGGTGGCTATGAGGCACAGGAGCCGCTGTGCCCAGCTGTG CCCCCTAGGAAGGCTGTCCCTGTCACCAGCTTCACCTACATCAATGAGGACTTCCGGACA GAGTCACCCCCCAGCCCAAGCAGTGATGTTGAGGATGCCCGAGAGCAGCGGGCACACAAT GCCCACCTCCGCGGCCCACCACCAAAGCTCATCCCTGTCTCTGGAAAGCTGGAGAAGAAC ATGGAGAAGATCCTGATCCGCCCAACAGCCTTCAAGCCAGTGCTGCCCAAACCTCGAGGG GCTCCGTCCCTGCCTAGCTTCATGGGTCCTCGGGCCACCGGGCTGTCTGGGAGCCAGGGC AGCCTGACGCAGCTGTTTGGGGGCCCTGCCTCCTCCTCCTCCTCTTCCTCCTCCTCTTCA GCTGCTGACAAACCCCTGGCATTTAGTGGCTGGGCCAGTGGCTGCCCATCAGGGACGCTA TCCGACTCTGGCCGAAACTCACTGTCCAGCCTGCCCACCTACAGCACCGGAGGTGCCGAG CCAACCACCAGCTCCCCAGGCGGGCACCTGCCTTCCCATGGCTCTGGGCGAGGGGCACTG CCTGGGCCAGCCCGAGGGGTCCCTACTGGGCCCTCCCACTCAGACAGTGGCCGGTCCTCC TCCAGCAAGAGCACAGGCTCCCTAGGGGGCCGTGTGGCTGGGGGGCTTTTGGGCAGTGGT ACTCGGGCCTCCCCTGACAGCAGCTCCTGTGGGGAGCGCTCACCACCACCCCCGCCTCCA CCTCCTTCGGATGAGGCCCTGCTGCACTGTGTCCTGGAAGGAAAGCTCCGAGACCGGGAG GCAGAGCTTCAGCAGCTGCGGGACAGTCTGGACGAGAATGAGGCTACCATGTGCCAGGCA TACGAGGAGCGGCAGCGGCACTGGCAGCGAGAGCGTGAGGCCCTGCGAGAGGACTGTGCG GCCCAGGCACAGCGGGCACAGCGGGCCCAACAGCTGCTGCAGCTGCAGGTGTTCCAGCTG CAGCAGGAGAAGCGGCAATTGCAGGACGACTTCGCACAGCTGCTGCAGGAGCGCGAACAG CTGGAGCGGCGCTGCGCCACCTTGGAGCGGGAGCAGCGGGAGCTCGGGCCGAGGCTTGAG GAGACCAAGTGGGAGGTGTGCCAGAAATCAGGCGAGATCTCCCTGCTGAAGCAGCAGCTG AAAGAGTCTCAGGCAGAGCTGGTGCAGAAGGGCAGCGAGCTGGTGGCTCTGCGGGTGGCG CTGCGGGAGGCCCGTGCTACGCTGCGGGTCAGTGAGGGCCGTGCGCGGGGTCTACAGGAG GCCGCCCGAGCTCGGGAGCTGGAGCTGGAAGCCTGTTCCCAGGAGCTGCAGCGACACCGC CAGGAAGCTGAGCAGCTGCGGGAGAAAGCTGGGCAGTTGGATGCTGAGGCGGCCGGACTC CGGGAGCCCCCTGTGCCACCTGCCACCGCTGACCCATTCCTCCTGGCAGAGAGTGATGAG GCCAAAGTGCAGCGGGCAGCAGCCGGGGTTGGGGGCAGCTTGCGGGCCCAGGTGGAGCGA TTGCGGGTGGAGCTGCAGCGGGAGCGGCGGCGGGGTGAGGAGCAGCGGGACAGCTTTGAG GGGGAGCGGCTGGCCTGGCAGGCAGAGAAGGAGCAGGTGATCCGCTACCAGAAGCAGCTG CAGCACAACTACATCCAGATGTACCGGCGCAACCGGCAGCTAGAGCAGGAGCTGCAGCAG CTCAGCCTGGAGCTGGAGGCCCGGGAGCTCGCTGACCTGGGCCTGGCCGAGCAGGCCCCC TGCATCTGCCTGGAGGAGATCACTGCTACTGAGATCTAGGGCCCTCAGCAACCAGCTCTG TAGGGAGCTCTGCCAGAGGGGCAGCAGCTGCAGATCCACTTAGGCCCCAGGGTCCACGGA TGGCCCCAAAGGCTGAGGGCCCCAAAGCCACTTGTCTCCTAGGATCCAGGCCTCTGGGCT TCTGCCAAGAACTCAGGGTGGCCCTATGACTTGGAGGAGCAAGATCAGACCGCTCAAAGG TCCCCGTGTTCACTGTTACCCAGAGGCTCTTGTTACTACCCACTTCATTCCCCACCGCTG CCAGTGCCACTGCCAACCCTGTTCACAGGCGCTTCCAGCCCACTCCAGCCAGGGGAGCAG GGAAGAAGAAGGGGCTCCCTCCTCTTCACATTCCCCCCGACCCCAAAGCCAGAGAAAGCC AGATGGCACCAGCTGCTCCGGATGTGCCTGCCCACATTGGGGGACAGGGCCGGGCCTGGG CTCGGTTCCCAGGTTTGAGCTCTGCAGCCTCTCTCCTGGAGTGAGGGGGCTGAAGTCAGA CCAAAGGAAGAACTCAGAAATGTCTTGTTTATTTGTGTTTGTGACCAAGCAGCCTCTCCC TTCACCCAGGTTTATGGCCTCGTTTTCACTTGTATATTTTTCACACTGTAAATTTCTTGT ACAAACCCAAAGAAAAAATTAAAAAAAATTTTTTTGTTTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_032429 |
| Insert Size | 2700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_032429.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032429.1, NP_115805.1 |
| RefSeq Size | 2757 bp |
| RefSeq ORF | 2010 bp |
| Locus ID | 84445 |
| UniProt ID | Q9BRK4 |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1, 2 and 3 all encode isoform a. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Regulates Lef/Tcf-dependent Transcription through Akt/GSK3ß Signaling Pathway in Lung Cancer
,Quan-Zhe Cui, Zhong-Ping Tang, Xiu-Peng Zhang, Huan-Yu Zhao, Qian-Ze Dong, Ke Xu, and En-Hua Wang,
Journal of Histochemistry & Cytochemistry, Jul 2013; 10.1369/0022155413495875.
,PubMed ID 23761130
[LZTS2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200824 | LZTS2 (Myc-DDK-tagged)-Human leucine zipper, putative tumor suppressor 2 (LZTS2) |
CNY 4,904.00 |
|
| RC200824L1 | Lenti ORF clone of Human leucine zipper, putative tumor suppressor 2 (LZTS2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200824L2 | Lenti ORF clone of Human leucine zipper, putative tumor suppressor 2 (LZTS2), mGFP tagged |
CNY 5,890.00 |
|
| RC200824L3 | Lenti ORF clone of Human leucine zipper, putative tumor suppressor 2 (LZTS2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200824L4 | Lenti ORF clone of Human leucine zipper, putative tumor suppressor 2 (LZTS2), mGFP tagged |
CNY 5,890.00 |
|
| RG200824 | LZTS2 (tGFP-tagged) - Human leucine zipper, putative tumor suppressor 2 (LZTS2) |
CNY 4,370.00 |
