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Anoctamin 3 (ANO3) (NM_031418) Human Untagged Clone
CAT＃: SC305338
ANO3 (untagged)-Human anoctamin 3 (ANO3)
CNY 7,192.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C11orf25; DYT23; DYT24; GENX-3947; TMEM16C |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_031418 edited
ATGGTCCACCATTCAGGCTCCATTCAGTCCTTTAAACAGCAAAAAGGTATGAATATAAGC AAGAGTGAGATAACAAAAGAAACTTCGTTAAAACCGTCTCGGAGATCCCTGCCTTGCCTC GCCCAGAGCTACGCTTACTCAAAGAGCTTGAGCCAGTCTACTTCCCTCTTCCAGTCAACC GAGAGTGAATCTCAGGCTCCCACATCTATAACCTTAATCTCCACTGACAAAGCAGAGCAA GTTAATACTGAGGAGAATAAAAACGACTCTGTGCTGAGATGTTCATTTGCTGACCTCAGC GATTTTTGTTTGGCCCTAGGAAAAGATAAGGATTACACGGATGAATCAGAACACGCTACT TATGACCGATCTCGTCTCATTAATGACTTTGTTATCAAAGATAAATCTGAATTCAAGACA AAATTATCTAAGAATGACATGAATTACATAGCATCCAGTGGACCTCTGTTCAAAGATGGC AAAAAGAGAATTGATTACATCTTGGTTTATAGAAAGACAAATATACAATATGATAAAAGA AACACATTTGAAAAGAACCTCAGAGCAGAAGGCTTGATGTTGGAGAAGGAGCCAGCTATT GCAAGCCCCGATATCATGTTTATTAAAATTCACATTCCATGGGACACGCTGTGCAAGTAT GCAGAGAGGCTGAATATCAGGATGCCCTTCAGGAAAAAATGCTATTACACTGACGGGAGG AGCAAATCAATGGGCAGGATGCAAACTTATTTTAGAAGAATCAAAAACTGGATGGCCCAA AACCCAATGGTTCTTGACAAGTCAGCTTTTCCAGACCTAGAGGAGTCAGACTGCTATACT GGCCCCTTCAGCCGTGCACGGATTCACCACTTCATAATAAATAATAAAGACACCTTCTTC AGCAATGCTACTCGAAGCAGAATAGTCTATCACATGCTGGAACGCACCAAATATGAAAAT GGAATATCAAAAGTGGGTATCCGTAAACTTATAAACAATGGCTCATACATAGCAGCGTTT CCACCACATGAGGGAGCCTACAAAAGTAGCCAGCCCATTAAAACCCATGGACCTCAGAAT AACAGACATCTATTATATGAGCGCTGGGCACGCTGGGGAATGTGGTATAAGCATCAGCCT CTGGATTTAATCAGGCTGTACTTTGGTGAGAAGATTGGACTATACTTTGCTTGGCTGGGA TGGTATACTGGAATGTTGATTCCTGCAGCAATTGTTGGTTTGTGCGTTTTCTTCTATGGA TTATTTACAATGAATAATAGTCAAGTAAGCCAAGAAATTTGTAAAGCCACTGAAGTCTTT ATGTGCCCTCTCTGTGACAAGAACTGCTCCCTGCAGAGACTCAACGACAGCTGTATCTAT GCCAAGGTGACATATTTGTTCGATAATGGAGGGACAGTCTTCTTTGCTATTTTTATGGCA ATATGGGCCACAGTCTTCCTGGAGTTTTGGAAAAGGAGAAGGAGTATACTGACCTATACT TGGGACCTTATCGAATGGGAAGAAGAGGAGGAAACACTTCGTCCCCAGTTTGAAGCCAAG TATTACAAGATGGAGATTGTAAATCCCATCACGGGAAAACCTGAACCACATCAGCCTTCC TCAGACAAAGTCACTCGTCTTCTTGTTTCTGTCTCAGGAATATTCTTCATGATATCCTTG GTGATCACTGCAGTGTTTGGAGTTGTGGTGTACCGCCTGGTTGTCATGGAACAGTTTGCA TCATTCAAGTGGAATTTCATCAAACAATACTGGCAGTTTGCAACATCTGCTGCTGCTGTC TGTATCAATTTCATAATCATTATGTTGCTGAATCTTGCTTATGAAAAAATTGCTTACCTC CTCACCAATTTAGAATATCCTCGAACAGAATCAGAGTGGGAAAACAGCTTCGCCCTGAAG ATGTTCCTCTTCCAGTTTGTCAATTTAAACAGTTCCATCTTCTATATCGCTTTCTTTTTG GGAAGATTTGTAGGCCACCCAGGAAAATACAATAAACTTTTTGACCGGTGGAGACTGGAG GAATGTCATCCTAGTGGCTGTTTGATAGACCTCTGCCTCCAGATGGGTGTCATCATGTTT TTGAAGCAAATATGGAACAACTTCATGGAACTAGGATACCCGTTGATCCAGAACTGGTGG TCACGACATAAAATCAAGCGGGGAATACATGATGCTTCCATACCTCAGTGGGAAAATGAT TGGAATCTGCAGCCCATGAACCTTCATGGACTGATGGATGAGTACTTAGAAATGGTTTTG CAATTTGGTTTTACCACCATCTTTGTTGCGGCTTTTCCTCTAGCCCCTCTTTTGGCTTTG TTAAACAATATCATTGAAATCAGGCTGGATGCATACAAATTTGTCACTCAATGGCGGAGG CCTTTGCCAGCCCGAGCAACTGACATAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGT ATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGT TTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGC TTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGA AAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCTTGGAGTTCCAAACCCTAT GAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTT GAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAG GGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCT GAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGG CCTTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_031418 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This clone has been fully sequenced and found three SNPs within the protein associated with this reference, NM_031418.1. No amino acid change was found. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_031418.1, NP_113606.1 |
| RefSeq Size | 6641 bp |
| RefSeq ORF | 2946 bp |
| Locus ID | 63982 |
| UniProt ID | Q9BYT9 |
| Protein Families | Transmembrane |
| Gene Summary | The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, contains an alternate 5' terminal exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223382 | ANO3 (Myc-DDK-tagged)-Human anoctamin 3 (ANO3) |
CNY 10,776.00 |
|
| RC223382L1 | Lenti ORF clone of Human anoctamin 3 (ANO3), Myc-DDK-tagged |
CNY 13,176.00 |
|
| RC223382L2 | Lenti ORF clone of Human anoctamin 3 (ANO3), mGFP tagged |
CNY 11,690.00 |
|
| RC223382L3 | Lenti ORF clone of Human anoctamin 3 (ANO3), Myc-DDK-tagged |
CNY 11,690.00 |
|
| RC223382L4 | Lenti ORF clone of Human anoctamin 3 (ANO3), mGFP tagged |
CNY 11,690.00 |
|
| RG223382 | ANO3 (tGFP-tagged) - Human anoctamin 3 (ANO3) |
CNY 12,376.00 |
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