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SIN3B (NM_015260) Human Untagged Clone
CAT＃: SC304274
SIN3B (untagged)-Human SIN3 homolog B, transcription regulator (yeast) (SIN3B)
CNY 22,330.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_015260, the custom clone sequence may differ by one or more nucleotides
ATGGCGCACGCTGGCGGTGGCAGCGGTGGCAGCGGTGCCGGCGGCCCCGCGGGCCGGGGG CTGAGCGGCGCCCGCTGGGGTCGCTCGGGCTCCGCAGGCCACGAGAAGCTGCCGGTGCAC GTAGAAGACGCCCTCACCTATCTGGACCAGGTGAAGATCCGCTTTGGCAGCGACCCTGCC ACCTACAACGGCTTCCTGGAGATCATGAAGGAGTTCAAAAGCCAGAGCATCGATACTCCT GGAGTCATCAGACGTGTCTCGCAGCTCTTCCACGAGCACCCTGACCTCATTGTTGGATTC AACGCTTTTCTTCCCCTCGGATATAGAATAGACATTCCCAAGAATGGCAAGTTAAACATA CAGTCGCCTCTGACAAGCCAGGAGAATTCGCACAACCACGGGGACGGTGCAGAGGACTTC AAGCAGCAGGTGCCGTATAAAGAGGACAAACCCCAGGTGCCCCTGGAGTCCGATTCCGTG GAATTCAACAACGCCATCAGCTATGTGAATAAGATTAAAACCCGCTTCCTAGACCACCCA GAAATCTACAGGTCATTCCTGGAGATCCTGCACACGTACCAGAAGGAGCAGCTGAACACG AGGGGCCGGCCATTCCGAGGCATGTCTGAAGAGGAGGTGTTCACCGAGGTGGCCAACCTC TTCCGGGGCCAGGAGGACCTGCTCTCAGAGTTTGGACAGTTCCTGCCCGAAGCCAAGCGG TCTCTGTTCACAGGAAACGGGCCGTGCGAGATGCACAGCGTGCAGAAGAACGAGCACGAC AAGACCCCGGAGCACAGCAGGAAGCGCTCCCGGCCCTCGCTCCTCCGCCCCGTGTCTGCA CCCGCCAAGAAAAAAATGAAACTTCGTGGTACCAAAGACCTGTCCATCGCTGCAGTGGGG AAGTACGGGACTCTGCAGGAATTTTCTTTCTTTGACAAGGTCCGCCGGGTGCTGAAGAGC CAGGAGGTGTATGAAAACTTCCTCCGCTGCATCGCACTCTTCAACCAGGAGCTGGTGTCT GGCTCTGAGCTCCTGCAGCTCGTCAGCCCATTTCTGGGGAAATTTCCAGAACTCTTTGCA CAGTTCAAGTCCTTCCTGGGGGTAAAAGAGCTGTCCTTCGCGCCACCCATGAGCGACAGA TCCGGGGACGGGATAAGCCGGGAAATTGATTATGCATCCTGCAAGCGCATAGGATCCAGC TACCGGGCACTCCCCAAAACCTACCAGCAGCCCAAGTGCAGTGGGAGGACAGCCATCTGC AAGGAGCTTGACCATTGGACACTTCTCCAGGGTTCGTGGACAGACGATTACTGCATGTCC AAGTTCAAGAATACCTGCTGGATTCCAGGATATAGTGCAGGGGTACTGAACGACACCTGG GTCTCCTTCCCTTCCTGGTCTGAGGACTCCACGTTCGTCAGCTCCAAGAAGACACCGTAC GAGGAGCAGCTTCACCGCTGTGAGGACGAGCGCTTCGAGTTAGACGTTGTCCTGGAGACG AACCTGGCCACAATCCGTGTGTTGGAAAGTGTGCAGAAGAAGCTGTCTCGGATGGCGCCG GAAGACCAGGAGAAGTTCCGGCTGGACGACTCCCTGGGAGGCACGTCGGAGGTGATCCAG CGCCGTGCCATTTATCGCATCTATGGCGACAAGGCCCCGGAGATCATCGAGAGCCTCAAG AAGAACCCTGTCACCGCTGTCCCCGTTGTCCTGAAAAGACTGAAGGCCAAGGAAGAGGAG TGGCGGGAGGCCCAGCAGGGCTTCAACAAGATCTGGCGGGAGCAGTATGAGAAGGCGTAC CTCAAGTCCCTTGACCACCAGGCTGTGAACTTCAAGCAGAACGACACCAAGGCCCTGCGC TCCAAGAGCTTGCTCAACGAGATCGAGAGCGTCTACGACGAGCACCAGGAGCAGCACTCG GAGGGCCGCAGTGCCCCCTCTAGCGAGCCGCACCTCATCTTTGTGTACGAGGACCGGCAG ATCCTGGAGGACGCAGCAGCGCTCATCAGCTACTACGTGAAGCGGCAGCCGGCCATCCAG AAGGAGGACCAGGGCACCATCCACCAGCTGCTGCACCAGTTCGTGCCCAGCCTCTTCTTC TCTCAGCAGCTGGACCTGGGCGCCTCCGAGGAGTCAGCTGATGAGGACCGGGACAGCCCC CAGGGGCAGACCACAGACCCCAGTGAGCGGAAGAAGCCGGCGCCAGGACCCCACAGTAGC CCCCCAGAGGAGAAGGGGGCCTTCGGGGATGCCCCGGCCACTGAGCAGCCACCCCTGCCG CCCCCAGCCCCGCACAAGCCCCTGGACGATGTCTACAGCCTATTTTTTGCCAACAACAAC TGGTACTTCTTCCTGCGCCTGCACCAGACCCTGTGCTCCAGGCTGCTGAAGATCTACCGC CAGGCGCAGAAGCAGCTTCTGGAGTATCGGACCGAGAAGGAGCGGGAGAAGCTGCTGTGT GAGGGCCGCAGGGAGAAGGGCAGCGACCCCGCCATGGAGCTGCGGCTGAAGCAGCCCAGT GAAGTGGAGCTGGAGGAGTACTACCCGGCCTTCCTGGACATGGTGCGGAGCCTGCTGGAG GGCAGCATCGACCCCACGCAGTACGAGGACACCCTACGCGAGATGTTCACCATCCATGCC TACGTGGGCTTCACCATGGACAAGCTGGTGCAGAACATTGCGCGGCAGCTGCACCACCTC GTGAGCGATGACGTCTGCCTGAAGGTGGTGGAGCTCTACCTGAACGAGAAGAAGCGGGGT GCCGCTGGTGGGAACCTGTCCTCCCGCTGCGTCCGCGCTGCTAGGGAGACCAGCTACCAG TGGAAGGCTGAGCGCTGCATGGCCGACGAGAACTGCTTCAAGGTGATGTTCCTGCAGCGC AAAGGGCAGGTGATCATGACCATCGAGCTCCTGGACACCGAGGAGGCCCAGACGGAGGAC CCTGTGGAGGTCCAGCACCTGGCTCGGTACGTGGAGCAGTATGTGGGGACCGAGGGCGCG TCCAGCTCGCCCACTGAGGGCTTCCTCCTGAAACCTGTGTTCCTGCAGAGGAACCTCAAG AAGTTCCGCCGCCGGTGGCAGAGCGAGCAGGCGCGGGCCCTGCGCGGTGAGGCCAGGAGC TCCTGGAAGCGGCTGGTGGGCGTGGAGAGCGCCTGCGACGTGGACTGCCGCTTCAAGCTC AGCACTCACAAGATGGTGTTCATCGTGAACTCCGAGGACTACATGTACCGTCGCGGGACC CTCTGCCGGGCCAAGCAGGTGCAGCCCCTGGTCCTGCTCCGCCACCACCAGCACTTTGAG GAGTGGCACAGCCGCTGGCTGGAGGACAATGTGACGGTGGAGGCGGCTAGCCTGGTGCAG GACTGGCTGATGGGTGAGGAGGACGAGGACATGGTACCCTGCAAGACGCTGTGTGAGACA GTGCACGTGCACGGCCTGCCCGTGACCCGCTACCGCGTGCAGTACAGCCGCCGCCCGGCC TCGCCCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_015260 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_015260.1, NP_056075.1 |
| RefSeq Size | 5129 bp |
| RefSeq ORF | 3489 bp |
| Locus ID | 23309 |
| UniProt ID | O75182 |
| Gene Summary | Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216859 | SIN3B (Myc-DDK-tagged)-Human SIN3 homolog B, transcription regulator (yeast) (SIN3B) |
CNY 12,136.00 |
|
| RC216859L1 | Lenti-ORF clone of SIN3B (Myc-DDK-tagged)-Human SIN3 homolog B, transcription regulator (yeast) (SIN3B) |
CNY 14,536.00 |
|
| RC216859L2 | Lenti-ORF clone of SIN3B (mGFP-tagged)-Human SIN3 homolog B, transcription regulator (yeast) (SIN3B) |
CNY 13,490.00 |
|
| RC216859L3 | Lenti-ORF clone of SIN3B (Myc-DDK-tagged)-Human SIN3 homolog B, transcription regulator (yeast) (SIN3B) |
CNY 13,490.00 |
|
| RC216859L4 | Lenti-ORF clone of SIN3B (mGFP-tagged)-Human SIN3 homolog B, transcription regulator (yeast) (SIN3B) |
CNY 13,490.00 |
|
| RG216859 | SIN3B (tGFP-tagged) - Human SIN3 homolog B, transcription regulator (yeast) (SIN3B) |
CNY 12,730.00 |
