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FBXW8 (NM_012174) Human Untagged Clone
CAT＃: SC303936
FBXW8 (untagged)-Human F-box and WD repeat domain containing 8 (FBXW8), transcript variant 2
CNY 8,550.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FBW6; FBW8; FBX29; FBXO29; FBXW6 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC303936 representing NM_012174.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGACGACTACAGCCTGGATGAGTTCCGTCGGCGCTGGCAGGAGGAGCTGGCGCAGGCCCAGGCGCCG AAGAAGCGGCGACGGCCCGAGGCTGCCGAGAGGCGGGCTCGGCGGCCGGAGAATGAAATGAATGATGTG CCTTTCTTTGATATCCAACTGCCTTACGAATTGGCAATCAATATATTTCAGTATCTGGACAGGAAAGAA CTAGGAAGATGTGCACAGGTGAGCAAGACGTGGAAGGTGATTGCAGAGGATGAGGTGCTGTGGTACAGG CTGTGCCAGCAGGAAGGGCACCTTCCGGATAGCAGCATCTCTGACTATTCTTGCTGGAAGCTCATCTTC CAAGAGTGCCGAGCCAAGGAACACATGTTACGAACCAACTGGAAGAATCGCAAAGGTGCCGTGAGCGAG CTGGAGCATGTTCCTGACACAGTTTTGTGTGATGTGCATTCTCACGATGGTGTGGTCATTGCGGGATAT ACATCAGGGGATGTGAGAGTGTGGGACACCCGCACCTGGGACTACGTAGCCCCCTTCCTGGAATCAGAG GACGAGGAGGATGAGCCTGGAATGCAGCCAAATGTCTCCTTTGTGAGGATAAACAGCTCGTTGGCAGTA GCAGCTTATGAGGATGGGTTTCTTAATATTTGGGATTTAAGGACCGGAAAGTACCCTGTTCATCGTTTT GAGCACGATGCAAGAATACAGGCACTAGCCCTCAGCCAGGACGATGCAACCGTGGCCACAGCTTCTGCT TTTGATGTCGTGATGTTATCCCCCAATGAGGAGGGGTACTGGCAGATAGCTGCGGAATTTGAAGTTCCG AAACTGGTTCAGTACCTTGAAATAGTTCCAGAAACCAGAAGGTACCCTGTGGCAGTAGCCGCTGCTGGA GATCTGATGTACCTGCTCAAAGCCGAAGACTCCGCCAGAACCCTCCTTTACGCCCACGGCCCGCCTGTC ACATGTCTAGACGTCTCGGCCAACCAAGTTGCTTTTGGTGTACAGGGTCTGGGATGGGTGTACGAAGGA AGCAAGATCCTGGTGTATAGCCTGGAAGCAGGACGCCGCCTCTTGAAGCTGGGTAACGTTCTCCGTGAC TTCACGTGTGTCAACCTCAGCGACAGCCCTCCCAACCTCATGGTCAGTGGCAACATGGACGGGAGGGTG AGGATCCACGACCTCCGCAGTGGTAACATCGCCCTGTCGCTCTCCGCCCATCAGCTCAGGGTCTCTGCT GTGCAGATGGATGACTGGAAGATCGTCAGTGGAGGCGAGGAAGGCCTGGTGTCCGTGTGGGATTATCGG ATGAACCAGAAGCTGTGGGAGGTGTATTCCGGGCACCCGGTGCAGCACATCTCATTCAGCAGCCACAGC CTCATCACGGCCAACGTGCCTTACCAGACGGTAATGCGAAACGCCGACCTGGACAGCTTCACTACTCAC AGGAGACACCGGGGGCTGATCCGCGCCTATGAGTTTGCGGTGGACCAGCTGGCCTTCCAGAGCCCTCTC CCTGTCTGCCGTTCATCCTGTGACGCCATGGCCACTCACTACTACGACCTCGCACTGGCCTTTCCCTAT AACCATGTTTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_012174 |
| Insert Size | 1599 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_012174.1 |
| RefSeq Size | 4673 bp |
| RefSeq ORF | 1599 bp |
| Locus ID | 26259 |
| UniProt ID | Q8N3Y1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Ubiquitin mediated proteolysis |
| MW | 60.7 kDa |
| Gene Summary | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an in-frame segment in the 5' coding region, as compared to variant 1. It encodes isoform 2, which is missing an internal segment, as compared to isoform 1. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213316 | FBXW8 (Myc-DDK-tagged)-Human F-box and WD repeat domain containing 8 (FBXW8), transcript variant 2 |
CNY 3,960.00 |
|
| RC213316L3 | Lenti ORF clone of Human F-box and WD repeat domain containing 8 (FBXW8), transcript variant 2, Myc-DDK-tagged |
CNY 6,560.00 |
|
| RC213316L4 | Lenti ORF clone of Human F-box and WD repeat domain containing 8 (FBXW8), transcript variant 2, mGFP tagged |
CNY 6,560.00 |
|
| RG213316 | FBXW8 (tGFP-tagged) - Human F-box and WD repeat domain containing 8 (FBXW8), transcript variant 2 |
CNY 5,130.00 |
