MICB (NM_005931) Human Untagged Clone
CAT#: SC303706
MICB (untagged)-Human MHC class I polypeptide-related sequence B (MICB)
CNY 6,270.00
Product images
CNY 1,999.00
CNY 3,600.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | PERB11.2 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_005931 edited
CCGGGATATCGTCGACCCACGCGTCCGAGCGGTCGCTGAGCGGGGCGCAGGTGACTAAAT TTCGACGGGGTCTTCTCACCGGTTTCATTCAGTTGGCCACTGCTGAGCAGCTGAGAAGGT GGCGACGTAGGGGCCATGGGGCTGGGCCGGGTCCTGCTGTTTCTGGCCGTCGCCTTCCCT TTTGCACCCCCGGCAGCCGCCGCTGAGCCCCACAGTCTTCGTTACAACCTCATGGTGCTG TCCCAGGATGGATCTGTGCAGTCAGGGTTTCTCGCTGAGGGACATCTGGATGGTCAGCCC TTCCTGCGCTATGACAGGCAGAAACGCAGGGCAAAGCCCCAGGGACAGTGGGCAGAAGAT GTCCTGGGAGCTGAGACCTGGGACACAGAGACCGAGGACTTGACAGAGAATGGGCAAGAC CTCAGGAGGACCCTGACTCATATCAAGGACCAGAAAGGAGGCTTGCATTCCCTCCAGGAG ATTAGGGTCTGTGAGATCCATGAAGACAGCAGCACCAGGGGCTCCCGGCATTTCTACTAC GATGGGGAGCTCTTCCTCTCCCAAAACCTGGAGACTCAAGAATCGACAGTGCCCCAGTCC TCCAGAGCTCAGACCTTGGCTATGAACGTCACAAATTTCTGGAAGGAAGATGCCATGAAG ACCAAGACACACTATCGCGCTATGCAGGCAGACTGCCTGCAGAAACTACAGCGATATCTG AAATCCGGGGTGGCCATCAGGAGAACAGTGCCCCCCATGGTGAATGTCACCTGCAGCGAG GTCTCAGAGGGCAACATCACCGTGACATGCAGGGCTTCCAGCTTCTATCCCCGGAATATC ACACTGACCTGGCGTCAGGATGGGGTATCTTTGAGCCACAACACCCAGCAGTGGGGGGAT GTCCTGCCTGATGGGAATGGAACCTACCAGACCTGGGTGGCCACCAGGATTCGCCAAGGA GAGGAGCAGAGGTTCACCTGCTACATGGAACACAGCGGGAATCACGGCACTCACCCTGTG CCCTCTGGGAAGGCGCTGGTGCTTCAGAGTCAACGGACAGACTTTCCATATGTTTCTGCT GCTATGCCATGTTTTGTTATTATTATTATTCTCTGTGTCCCTTGTTGCAAGAAGAAAACA TCAGCGGCAGAGGGTCCAGAGCTTGTGAGCCTGCAGGTCCTGGATCAACACCCAGTTGGG ACAGGAGACCACAGGGATGCAGCACAGCTGGGATTTCAGCCTCTGATGTCAGCTACTGGG TCCACTGGTTCCACTGAGGGCGCCTAGACTCTACAGCCAGGCGGCCAGGATTCAACTCCC TGCCTGGATCTCACCAGCACTTTCCCTCTGTTTCCTGACCTATGAAACAGAGAAAATAAC ATCACTTATTTATTGTTGTTGGATGCTGCAAAGTGTTAGTAGGTATGAGGTGTTTGCTGC TCTGCCACGTAGAGAGCCAGCAAAGGGATCATGACCAACTCAACATTCCATTGGAGGCTA TATGATCAAACAGCAAATTGTTTATCATGAATGCAGGATGTGGGCAAACTCACGACTGCT CCTGCCAACAGAAGGTTTGCTGAGGGCATTCACTCCATGGTGCTCATTGGAGTTATCTAC TGGGTCATCTAGAGCCTATTGTTTGAGGAATGCAGTCTTACAAGCCTACTCTGGACCCAG CAGTTGACTCCTTCTTCCACCCCTCTTCTTGCTATCTCCTATACCAATAAATACGAAGGG CTGTGGAAGATCAGAGCCCTTGTTCACGAGAAGCAAGAAGCCCCCTGACCCCTTGTTCCA AATATACTCTTTTGTCTTTCTCTTTATTCCCACGTTTGCCCTTTGTTCAGTCCAATACAG GGTTGTGGGGCCCTTAACAGTGCCATATTAATTGGTATCATTATTTCTGTTGTTTTTGTT TTTGTTTTTGTTTTTGTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGCAGTTCAC TGGTGTGATCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCACTTCTCGTACCTC AGACTCCCGAATAGCTGGGATTACAGACAGGCACCACCACACCCAGCTAATTTTTGTATT TTTTGTAGAGACGGGGTTTCGCCAAGTTGACCAGCCCAGTTTCAAACTCCTGACCTCAGG TGATCTGCCTGCCTTGGCATCCCAAAGTGCTGGGATTACAAGAATGAGCCACCGTGCCTG GCCTATTTTATTATATTGTAATATATTTTATTATATTAGCCACCATGCCTGTCCTATTTT CTTATGTTTTAATATATTTTAATATATTACATGTGCAGTAATTAGATTATCATGGGTGAA CTTTATGAGTGAGTATCTTGGTGATGACTCCTCCTGACCAGCCCAGGACCAGCTTTCTTG TCACCTTGAGGTCCCCTCGCCCCGTCACACCGTTATGCATTACTCTGTGTCTACTATTAT GTGTGCATAATTTATACCGTAAATGTTTACTCTTTAAATAGAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_005931 unedited
TAGCTTTTGTATACGACTCCTATAGGGCGGCCGCTGAATTCAGATCTGGTACCGGTCCGG AATTCCCGGGATATCGTCGACCCACGCGTCCGAGCGGTCGCTGAGCGGGGCGCAGGTGAC TAAATTTCGACGGGGTCTTCTCACCGGTTTCATTCAGTTGGCCACTGCTGAGCAGCTGAG AAGGTGGCGACGTAGGGGCCATGGGGCTGGGCCGGGTCCTGCTGTTTCTGGCCGTCGCCT TCCCTTTTGCACCCCCGGCAGCCGCCGCTGAGCCCCACAGTCTTCGTTACAACCTCATGG TGCTGTCCCAGGATGGATCTGTGCAGTCAGGGTTTCTCGCTGAGGGACATCTGGATGGTC AGCCCTTCCTGCGCTATGACAGGCAGAAACGCAGGGCAAAGCCCCAGGGACAGTGGGCAG AAGATGTCCTGGGAGCTGAGACCTGGGACACAGAGACCGAGGACTTGACAGAGAATGGGC AAGACCTCAGGAGGACCCTGACTCATATCAAGGACCAGAAAGGAGGCTTGCATTCCCTCC AGGAGATTAGGGTCTGTGAGATCCATGAAGACAGCAGCACCAGGGGCTCCCGGCATTTCT ACTACGATGGGGAGCTCTTCCTCTCCCAAAACCTGGAGACTCAAGAATCGACAGTGCCCC AGTCCTCCAGAGCTCAGACCTTGGCTATGAACGTCACAAATTTCTGGAAGGAAGATGCCA TGAAGACCAAGACACACTATCGCGCTATGCAGGCAGACTGCCTGCAGAAACTACAGCGAT ATCTGAAATCCCGGGGTGGCCATCAGAGACAGTGCCCCCCATGGTGAATGTCACCTGCAG CGAGGTCTCAGAGGGCAACATCACCGTGACATGCAGGGCTTCCAGCTTCTATCCCCGGAA TATCCACACTGACCTG |
Restriction Sites | Please inquire |
ACCN | NM_005931 |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_005931.2, NP_005922.1 |
RefSeq Size | 2385 bp |
RefSeq ORF | 1152 bp |
Locus ID | 4277 |
UniProt ID | Q29980 |
Domains | MHC_I, ig, IGc1 |
Protein Families | Druggable Genome |
Protein Pathways | Natural killer cell mediated cytotoxicity |
Gene Summary | This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC222315 | MICB (Myc-DDK-tagged)-Human MHC class I polypeptide-related sequence B (MICB) |
CNY 5,488.00 |
|
RC222315L1 | Lenti ORF clone of Human MHC class I polypeptide-related sequence B (MICB), Myc-DDK-tagged |
CNY 7,888.00 |
|
RC222315L2 | Lenti ORF clone of Human MHC class I polypeptide-related sequence B (MICB), mGFP tagged |
CNY 5,890.00 |
|
RC222315L3 | Lenti ORF clone of Human MHC class I polypeptide-related sequence B (MICB), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC222315L4 | Lenti ORF clone of Human MHC class I polypeptide-related sequence B (MICB), mGFP tagged |
CNY 7,888.00 |
|
RG222315 | MICB (tGFP-tagged) - Human MHC class I polypeptide-related sequence B (MICB) |
CNY 7,088.00 |