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E2F2 (NM_004091) Human Untagged Clone
CAT＃: SC303431
E2F2 (untagged)-Human E2F transcription factor 2 (E2F2)
CNY 3,656.00
CNY 7,220.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | E2F-2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004091 edited
GCCTTACTCGCTATGCTGCAAGGGCCCCGGGCCTTGGCTTCGGCCGCTGGGCAGACCCCG AAGGTGGTGCCCGCGATGAGCCCCACAGAGCTGTGGCCATCCGGCCTCAGCAGCCCCCAG CTCTGCCCAGCTACTGCTACCTACTACACACCGCTGTACCCGCAGACGGCGCCTCCCGCA GCGGCGCCAGGCACCTGCCTCGACGCCACTCCCCACGGACCCGAGGGCCAAGTTGTGCGA TGCCTGCCGGCAGGCCGGCTGCCGGCCAAAAGGAAGCTGGATCTGGAGGGGATTGGGAGG CCCGTCGTCCCTGAGTTCCCAACCCCCAAGGGGAAGTGCATCAGAGTGGATGGCCTCCCC AGCCCCAAAACCCCCAAATCCCCCGGGGAGAAGACTCGGTATGACACTTCGCTGGGGCTG CTCACCAAGAAGTTCATTTACCTCCTGAGCGAGTCAGAGGATGGGGTCCTGGACCTGAAC TGGGCCGCTGAGGTGCTGGACGTGCAGAAGCGGCGCATCTATGACATCACCAACGTGCTG GAAGGCATCCAGCTCATCCGCAAGAAGGCCAAGAACAACATCCAGTGGGTAGGCAGGGGA ATGTTTGAAGACCCCACCAGACCTGGGAAGCAGCAACAGCTGGGGCAGGAGCTGAAGGAG CTGATGAACACGGAGCAGGCCTTGGACCAKCTCATCCAGAGCTGCTCTCTGAGCTTCAAG CACCTGACTGAGGACAAGGCCAACAAGAGGCTGGCCTATGTGACTTACCAGGATATCCGT GCTGTTGGCAACTTTAAGGAGCAGACAGTGATTGCCGTCAAGGCCCCTCCGCAGACGAGA CTGGAAGTGCCCGACAGGACTGAGGACAACCTGCAGATATATCTCAAGAGCACCCAAGGG CCCATCGAAGTCTACCTGTGCCCAGAGGAGGTGCAGGAGCCGGACAGTCCTTCCGAGGAG CCTCTCCCCTCTACCTCCACCCTCTGCCCCAGCCCTGACTCTGCCCAGCCCAGCAGCAGC ACCGACCCTAGCATCATGGAGCCCACAGCATCCTCAGTGCCAGCACCAGCGCCAACCCCC CAGCAGGCCCCACCGCCTCCATCCCTGGTCCCCTTGGAGGCTACTGACAGCCTGCTGGAG CTGCCGCACCCACTCCTGCAGCAGACTGAGGACCAGTTCCTGTCCCCGACCCTGGCGTGC AGCTCCCCTCTGATCAGCTTCTCCCCATCCTTGGACCAGGACGACTACCTGTGGGGCTTG GAGGCGGGTGAGGGCATCAGCGATCTCTTCGACTCCTACGACCTTGGGGACCTGTTGATT AATTGAGTGGCCCCGCCTGCCCCCAGCAGCCTGCCCCCGACTCTACCTCCTCACAGACAG GCTGACAGCCCCTCTGCCTGCACAGGGACATTGGACACTAGGTGCTGCCCTCAGGGCATG GGGTCTCCTCGCCTTTCCTGCCCCAGCCGGCAGAAGCTGTGTGGGGAGATATGAATGGTA CGGGTGAGGAGTGGATAAGGGGTGGTCCTCACCTTCCTAATGGAAGCTGGGCCTAGGGAG GCCCATCCAGTCTTCTGACTTCTGACCTCTCACAAGAAGGCTGCAGGTGAGGTGGCCAAG TCCAGGGAAAGGCCCTGCTACCTCCTTTTGAGGGGTAATTAGGACCCTCGACGTACCAAG AAGCACATAATGCCTTTGTATTTATTTCAGGTTGAGTTGTTTGTTTGTCCTCCCTGAGTT TTAGCAGGGAGGTTGTTCTAGTTTTTAGTGAGACCTCTGCAGACAGGCCCATCACTGTCC ATGTTCCAGGGCAGGTCTGGGTTTCCAAGGGAGGGGCCCAGGCTACATCCTTGGTTTCCC CACTGTGGTGGGGGCTGGGACTCTGAGGGGCTGTCCAGTCTGCCAGAATGCTAATTGCAC TTAGGCCTCATGGTTCTAGTAAACGGCAGCTGTGGGCCCTTTTGCCTCTTCCCCTGTTCT TGGCCTCACATCTCCAGCTGAGCTGCCGGTCTTGGCTTCCTGGTCGCCTCTGTCCCAGAG ATGGTCCCAGGGAGCCATCCTAGGGCAGGTAGCACTGAGGCTCCTGTGGAAACAGGAGCC ACCTGCTCAGGAGACCCCTTTCCTGAGGAAGTCCTTACCTCTCCCCTTGAGATGTAAAAA TGGTCCAGCAGAGACAAGCTCCCGTGGAAAACAGACAGGAGCATGGGGGCAGCTGTCATG GCTGTGGCGGGCACTTTTCCTCAGAGTTTCTGCCTTGCGCTGGTCCAGGAGCCATTTTGC ACCAAGGACTTGGTAGGCAGAGGCAGCCCCACTGTAAAGAAGGGTCAGATTAAAACAAAA AACTGCCAAAAGCATCCCCTCTGCCCCCCATGTGGCACTGGCATCATTCTCTGCTTCCCT GGGAGGAATTTTTTCACCATGTTATTGAAGGGGATGGTTCATTAAGGACTCCACCCCTCA GAGCTCACTCAGACCCCAAGGACAGAGGTGACTGGGGCTTGGTGACTTGTTCACTCCTTT TTTCCCAGGTATACTGAAGGGGTGACAGAGAGAGGTCTTCATGGCAGACCAGGCCTTCAC AGCTAATGGGGAGAGGAACTCATGTTACCTCTGCAGGCCTGGGGTCCTGAGGGGGTCTTT TGGCTTCAGCCTGTTCCCCCAGAGGCTTGATCATCCCACATTGTCCCTTCAGCTCAGCTG CTCTTCTCCCCCACCCACCCTGGGATGTGGGTGCTCTGGGCTGAACCAAGGCTATGACTT CTGGAGAGAGGCTCAGGGGTTGGTCTGAGAGGCCTGCCATCCACCCCTCAGGGAGCTAGG TTTTCTCAGAGGCTCAGCTGGACAGCACTTTTTAGAAAAGTTTGTAGCATTAAGCTGGTT TAAAATATGAAGTTGGTTTTGTTGGATGGCTCCTGAGCTGACTGACTGATGTCTGAAGTT TGAGACGAGGGATTATTTCAGGGTGGGGCCCAATGTGATCTAATGCCCAGCTGGGGACAA TTGTGCCTCATCATTTGCTCAAATTCCTGGGCCCCCAAGTTAGCCCCCTCCCAGGAGTGG TCAGCGGGTCACAGCTGCCCCCACTCTATAAGCAGGGCTAATTGTGTACCCTTTGCAGAA ATGCTTTTGGTCTCCTACCCAAATACTCACAAGGGTCTTATCAGACGCCCGTCTTAAAGT CCAGCATGCTCAGGGACCCTGTGTAGGATCTTGTTTGTGGTGAGTGGGCTGCTCTGAGGT CTCCACTGGGCTGCCATTTAGCCATGTGCCATCTCTGAAGTCAGAGGTGTTTGACTCCCA TTCCTTGGGCTCTGGAGCTTTCCCCAAGAATTACATCAGAGAAAAGGAAGAAGGGGCCTG CAGGACCCATTGGGAATGAGTTTAATACTGAAGTCTGGAATGTAAGCTCATGCCCTAGAG GCCTCTCCATATGGCTGGTCAGGGGAGCTGCCTTCAGGCTTGTGCCCCGTGTGCTCAGCA GCTGCCTCTGTCCCCCTCTACTGTCCCTTTCACACCTTGCCTGGCCAAGGGGCTAGACCT CCCAGGCTAAGCCTCAGATTCAGTGCAGGACACAAGCTCATGCCCCCGTCTTGCCAGTGA CACTTGAAGCCTCCCGACTTCCACAGAGTGCTTCAGGACACATTTTGAGTGGTATTTTCT TTTCTTTTTTTCTTCTTTTTTTTTTTTTTTTGAGATGGAGTCTCGTTCTGTTGCCCAGGC TGGAGTGCAGTGGCCTGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATT CTTCTGCCTCAGCCTCCAGAGTAGCTGGGACTATAGACATGCACCACCACGCCCGGCTAA TTTTGTATTTTTGGTCGAGACGGGGTTTTGCCATGTTAGTCAGGCTGGTCTTGAACTCCT GACCTCAAGTGATCCACCACCTCGGCCTCCCAAAGTGTTGAGATGACAGGCACGAGCCAC CAGGCCCAGCCTGAGTGGTATTTTCTTTAGGGACCAGGTAGACTTTAAAACGAGGGTAAG AGAAAAGCCAGTGTCTTTCTGAGGTAAATAATTTCTGCCAGGAAACTTCCCAGCCCCACC AGCAGCCACCCTAAAAAAAATCACTCGTGTCCCCAGGGACTTCTAAAGCTTGGGGCTCCA GGAAATCATCCAGTAGAGTTGGAGATTCAGAGATTTCTTGAAGCCAGGGACATGCTCCTA ACTCCTTTCCCATTAAAGGTGTTAGAATAGACCAGAGGGTGTCCCTTTTCCACAGTAATG GGATCGGCTGGTGTGCCTTCAGGGAGGAAGAGGGAGGTGGTCAAGCTTGAAAAACTGGCT TTAGGATGGTTCTGACTTTGTTCTCCCTCCCCAAGTGTTCTCAACCTCCATTCTGCAGTG TTCAGAGTTTTAGGGAAAGGGTTTGGGTGCCCCAGCATCCAGGTGTTGTGTGGCTTAGCG CATGTGAAGTGAAAACCTTCTGGGGTTGTTTGGAAGCAGCTTTCTGGTTCTTGTGATTGT ATCCTGAGGTCCCAGAACCCTATTCTCCCACGAGGATCCTCAGTGACCATGGTGGCCACA CGCCTGGCCAGCCTGCTGGCTCCTGGGTGAGCTGAAGAACCTTGCCTGTGGCACTTTTCG AGGGTGAGCTGGAACCGAGAGAACATGGTCCCCGTGCTGGGACTCATGCGGGTCATTTCC TGCCGGCCTGGTTTCGCCTGGTCGTGTCTTTATGAGCACCATGTAAGCCTCCTTGTATTG AGATAATTGGGCATTAAACATTAAACTGCAGCTCTGGGAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_004091 |
| Insert Size | 4800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and the protein assoicated with this clone was found to be identical to protein encoded by NM_004091.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004091.2, NP_004082.1 |
| RefSeq Size | 5273 bp |
| RefSeq ORF | 1314 bp |
| Locus ID | 1870 |
| UniProt ID | Q14209 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer |
| Gene Summary | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry
,Heiyoun Jung, Benjamin Hsiung, Kathleen Pestal, Emily Procyk, and David H. Raulet,
J. Exp. Med., Dec 2012; 209: 2409 - 2422.
[E2F2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208773 | E2F2 (Myc-DDK-tagged)-Human E2F transcription factor 2 (E2F2) |
CNY 3,656.00 |
|
| RC208773L3 | Lenti ORF clone of Human E2F transcription factor 2 (E2F2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC208773L4 | Lenti ORF clone of Human E2F transcription factor 2 (E2F2), mGFP tagged |
CNY 5,890.00 |
|
| RG208773 | E2F2 (tGFP-tagged) - Human E2F transcription factor 2 (E2F2) |
CNY 4,370.00 |
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