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IRS2 (NM_003749) Human Untagged Clone
CAT＃: SC303374
IRS2 (untagged)-Human insulin receptor substrate 2 (IRS2)
CNY 13,744.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IRS-2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003749 edited
GCCTGAAGCGCCCGCGATGGCGAGCCCGCCGCGGCACGGGCCGCCCGGGCCGGCGAGCGG AGACGGCCCCAACCTCAACAACAACAACAACAACAACAACCACAGCGTGCGCAAGTGCGG CTACCTGCGCAAGCAGAAGCATGGCCACAAGCGCTTCTTCGTGCTGCGCGGACCCGGCGC GGGCGGCGACGAGGCGACGGCGGGCGGGGGGTCGGCGCCGCAACCGCCGCGGCTCGAGTA CTACGAGAGCGAGAAAAAGTGGCGGAGCAAGGCAGGCGCGCCGAAACGGGTGATCGCTCT CGACTGCTGCCTGAACATCAACAAGCGCGCCGACGCCAAGCACAAGTACCTGATCGCCCT CTACACCAAGGACGAGTACTTCGCCGTGGCCGCCGAGAACGAGCAGGAGCAGGAGGGCTG GTACCGCGCGCTCACCGACCTGGTCAGCGAGGGCCGCGCGGCCGCCGGAGACGCGCCCCC CGCCGCCGCGCCCGCCGCGTCCTGCAGCGCCTCCCTGCCCGGCGCCCTGGGCGGCTCTGC CGGCGCCGCCGGGGCCGAGGACAGCTACGGGCTGGTGGCTCCCGCCACGGCCGCCTACCG TGAGGTGTGGCAGGTGAACCTGAAGCCCAAGGGTCTGGGCCAGAGCAAGAACCTGACGGG GGTGTACCGTCTGTGCCTGTCTGCGCGCACCATCGGCTTCGTGAAGCTCAACTGCGAGCA GCCGTCGGTGACGCTGCAGCTCATGAACATCCGCCGCTGCGGCCACTCGGACAGCTTCTT CTTCATCGAGGTGGGCCGCTCGGCCGTCACAGGCCCCGGCGAGCTGTGGATGCAGGCGGA CGACTCGGTGGTGGCGCAGAACATCCACGAGACCATCCTGGAGGCCATGAAGGCGCTCAA GGAGCTCTTCGAGTTCCGGCCGCGCAGTAAGAGCCAATCGTCGGGGTCGTCGGCCACGCA CCCCATCAGCGTCCCCGGCGCGCGCCGCCACCACCACCTGGTCAACCTGCCCCCCAGCCA GACGGGCCTGGTGCGCCGCTCGCGCACCGACAGCCTGGCCGCCACCCCGCCGGCGGCCAA GTGCAGCTCGTGCCGGGTGCGCACCGCCAGCGAGGGCGACGGCGGCGCGGCGGCGGGAGC GGCGGCCGCGGGCGCCAGGCCGGTGTCGGTGGCTGGGAGCCCCCTGAGCCCCGGGCCGGT GCGCGCGCCCCTGAGCCGCTCGCACACCCTGAGCGGCGGCTGCGGCGGCCGCGGGAGCAA GGTGGCGCTGCTGCCGGCAGGGGGCGCGCTGCAACACAGCCGCTCCATGTCCATGCCCGT GGCGCACTCGCCGCCCGCCGCCACCAGCCCCGGCTCCCTGTCGTCCAGCAGCGGCCACGG CTCGGGCTCCTACCCGCCGCCGCCCGGCCCGCACCCGCCTCTGCCGCATCCGCTGCACCA CGGCCCCGGCCAGCGGCCCTCCAGCGGCAGCGCCTCCGCCTCGGGCTCCCCCAGCGACCC CGGCTTCATGTCCCTGGACGAGTACGGCTCCAGCCCAGGCGACCTGCGCGCCTTCTGCAG CCACCGAAGCAACACGCCCGAGTCCATCGCGGAGACGCCCCCGGCCCGAGACGGCGGCGG CGGCGGTGAGTTCTACGGGTACATGACCATGGACAGGCCCCTGAGCCACTGTGGCCGCTC CTACCGCCGGGTCTCGGGGGACGCGGCCCAGGACCTGGACCGAGGGCTGCGCAAGAGGAC CTACTCCCTGACCACGCCAGCCCGGCAGCGGCCGGTGCCCCAGCCCTCCTCTGCCTCGCT GGATGAATACACCCTGATGCGGGCCACCTTCTCGGGCAGCGCGGGCCGCCTCTGCCCGTC CTGCCCCGCGTCCTCTCCCAAGGTGGCCTACCACCCCTACCCAGAGGACTACGGAGACAT CGAGATCGGCTCCCACAGGAGCTCCAGCAGCAACCTGGGGGCAGACGACGGCTACATGCC CATGACGCCCGGCGCGGCCCTCGCGGGCAGTGGGAGCGGCAGCTGCAGGAGCGACGACTA CATGCCCATGAGCCCCGCCAGCGTGTCCGCCCCCAAGCAGATCTTGCAGCCCAGGGCCGC CGCCGCCGCCGCCGCCGCCGTGCCTTCTGCGGGGCCTGCGGGGCCAGCACCCACCTCTGC GGCGGGCAGGACATTCCCGGCGAGCGGGGGCGGCTACAAGGCCAGCTCGCCCGCCGAGAG CTCCCCCGAGGACAGTGGGTACATGCGCATGTGGTGCGGTTCCAAGCTGTCCATGGAGCA TGCAGATGGCAAGCTGCTGCCCAACGGGGACTACCTCAACGTGTCCCCCAGCGACGCGGT CACCACGGGCACCCCGCCCGACTTCTTCTCCGCAGCCCTGCACCCCGGCGGGGAGCCGCT CAGGGGCGTTCCCGGCTGCTGCTACAGCTCCTTGCCCCGCTCCTACAAGGCCCCCTACAC CTGTGGCGGGGACAGCGACCAGTACGTGCTCATGAGCTCCCCCGTGGGGCGCATCCTGGA GGAGGAGCGTCTGGAGCCTCAGGCCACGCCAGGGCCCAGCCAGGCGGCCAGCGCCTTCGG GGCCGGCCCCACGCAGCCCCCTCACCCTGTAGTGCCTTCGCCCGTGCGGCCTAGCGGCGG CAGCCCGGAGGGCTTCTTGGGCCAGCGCGGCCGGGCGGTGAGGCCCACGCGCCTGTCCCT GGAGGGGCTGCCCAGCCTGCCCAGCATGCACGAGTACCCACTGCCACCGGAGCCCAAGAG CCCCGGCGAGTACATCAACATCGACTTTGGCGAGCCCGGGGCCCGCCTGTCGCCGCCCGC GCCTCCCCTGCTGGCGTCGGCGGCCTCGTCCTCCTCGCTCTTGTCCGCCAGCAGCCCGGC CTCGTCGCTGGGCTCAGGCACCCCGGGCACCAGCAGCGACAGCCGGCAGCGGTCTCCGCT CTCCGACTACATGAACCTCGACTTCAGCTCCCCCAAGTCTCCTAAGCCGGGCGCCCCGAG CGGCCACCCCGTGGGCTCCTTGGACGGCCTCCTGTCCCCCGAGGCCTCCTCCCCGTATCC GCCGTTGCCCCCGCGTCCGTCCGCGTCCCCGTCGTCGTCTCTGCAGCCGCCGCCACCGCC GCCGGCCCCGGGGGAGCTGTACCGCCTGCCCCCCGCCTCGGCCGTTGCCACCGCCCAGGG CCCGGGCGCCGCCTCATCGTTGTCCTCGGACACCGGGGACAATGGTGACTACACCGAGAT GGCTTTTGGTGTGGCCGCCACCCCGCCGCAACCTATCGCGGCCCCCCCGAAGCCAGAAGC TGCCCGCGTGGCCAGCCCGACGTCGGGCGTGAAGAGGCTGAGCCTCATGGAGCAGGTGTC GGGAGTCGAGGCCTTCCTGCAGGCCAGCCAGCCCCCGGACCCCCACCGCGGCGCCAAGGT CATCCGCGCAGACCCGCAGGGGGGCCGCCGCCGCCACAGTTCCGAGACCTTCTCCTCCAC CACGACGGTCACCCCCGTGTCCCCGTCCTTCGCCCACAACCCCAAGCGCCACAACTCGGC CTCCGTGGAAAATGTCTCTCTCAGGAAAAGCAGCGAGGGCGGCGTGGGTGTCGGCCCTGG AGGGGGCGACGAGCCGCCCACCTCCCCACGACAGTTGCAGCCGGCGCCCCCTTTGGCACC GCAGGGCCGGCCGTGGACCCCGGGTCAGCCCGGGGGCTTGGTCGGTTGTCCTGGGAGCGG TGGATCGCCCATGCGCAGAGAGACCTCTGCCGGCTTCCAGAATGGTCTCAACTACATCGC CATCGACGTGAGGGAGGAGCCCGGGCTGCCACCCCAGCCGCAGCCGCCGCCGCCGCCGCT TCCTCAGCCGGGAGACAAGAGCTCCTGGGGCCGGACCCGAAGCCTCGGGGGTCTCATCAG CGCTGTGGGCGTCGGCAGCACCGGCGGCGGGTGCGGGGGGCCGGGTCCCGGTGCCCTGCC CCCTGCCAACACCTACGCCAGCATTGACTTCTTGTCCCACCACTTGAAGGAGGCCACCAT CGTGAAAGAGTGAAGATCTGTCTGGCTTTATCACCAGGATGTCACATGTCAGAGAATATC ATTAAAAGAAGACGCTCAGCACTGTTTCAGCCCGAAGCTGCTTGCAGTTTTCTTTTGGAT CTGAGCAATGACTGTGTTTGGAAACATCTGTGGACTCTGTTAGATGAGGCACCAACAAGG CAAGGTCACCTGCCTCTTTCCCTTGTTCCCGGATGGGGCATTCATCATTGTGCTGTTTGC GTTTTGTTTTGTTTTGTTTTAACAAAATTAGCTGAAGAAGTTATTCTCAAGAAAATTGGA TGTTTTCATTGGCCTTCTTAAATTGTGGCCAGTGTCTTTTAATTTCTTCTTCTTTTCCTT TTGGCAAAGCAGATATAACCCTCAGCATGCTAGGAGAGTGCACCCGTACCTATGGAAGTG GTAAAATCTGGTATTTACTGGCTTACACTCAAAACGACCACAGTCCTACCTCAGTTCAAG GTAAAGCCGGATTTCCGTGGCGGGGGTCCCACAGGACCTCCTGTAGTAGCCCCTGCGCTG TGTGTCTGGAGCGCGGTCCTCGGCCTTATTGAAATGGTCCAAGTAGACAGCTGCTTGTTG GATTCCAGTGCAGGTACCTGCGATGTTTACGTCCACACCGAGCCCAGTGTGGGACTGACA TTTCTCAATGGAAGTGAAATTTGGGATTGGACTTTGAAGACGGATTACTAAATAATAATT ATTATATGTAACTGAAGCAACCTACTTTTGAAAATCAACTGTATTGGGTAGTGGGAGGTG GGAGGGAAGGGCTTTGGGAAGGGGATGAATATTTTTTTTTACCTTTAACAGACTTGTTTA ATCTTCTCGATGTAGATGTTTATGTAGGTACTTCACATTGCAAACGCCTTTTATT |
| Restriction Sites | Please inquire |
| ACCN | NM_003749 |
| Insert Size | 4900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003749.2, NP_003740.2 |
| RefSeq Size | 7014 bp |
| RefSeq ORF | 4017 bp |
| Locus ID | 8660 |
| UniProt ID | Q9Y4H2 |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus |
| Gene Summary | This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212413 | IRS2 (Myc-DDK-tagged)-Human insulin receptor substrate 2 (IRS2) |
CNY 13,728.00 |
|
| RC212413L1 | Lenti ORF clone of Human insulin receptor substrate 2 (IRS2), Myc-DDK-tagged |
CNY 16,128.00 |
|
| RC212413L2 | Lenti ORF clone of Human insulin receptor substrate 2 (IRS2), mGFP tagged |
CNY 15,200.00 |
|
| RC212413L3 | Lenti ORF clone of Human insulin receptor substrate 2 (IRS2), Myc-DDK-tagged |
CNY 15,200.00 |
|
| RC212413L4 | Lenti ORF clone of Human insulin receptor substrate 2 (IRS2), mGFP tagged |
CNY 16,128.00 |
|
| RG212413 | IRS2 (tGFP-tagged) - Human insulin receptor substrate 2 (IRS2) |
CNY 15,328.00 |
