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LRP4 (NM_002334) Human Untagged Clone
CAT＃: SC303182
LRP4 (untagged)-Human low density lipoprotein receptor-related protein 4 (LRP4)
CNY 19,216.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLSS; CMS17; LRP-4; LRP10; MEGF7; SOST2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002334 edited
GCTCTGGCAGCACTGGAGGCGGCGGCGGCCCGAGGGCGACTTGCGGGGCGCGCAGGCCGC CGTGCACCCGGGACGCTTCCCCCTCGGGGACCCTCCGCGGGCTTCTCCGCCGCGCCGTCC GGCGGGAGCCGGCGGGACCCCGGGCGAGCGGCGCGGGCGGCACCATGAGGCGGCAGTGGG GCGCGCTGCTGCTTGGCGCCCTGCTCTGCGCACACGGCCTGGCCAGCAGCCCCGAGTGTG CTTGTGGTCGGAGCCACTTCACATGTGCAGTGAGTGCTCTTGGAGAGTGTACCTGCATCC CTGCCCAGTGGCAGTGTGATGGAGACAATGACTGCGGGGACCACAGCGATGAGGATGGAT GTATACTACCTACCTGTTCCCCTCTTGACTTTCACTGTGACAATGGCAAGTGCATCCGCC GCTCCTGGGTGTGTGACGGGGACAACGACTGTGAGGATGACTCGGATGAGCAGGACTGTC CCCCCCGGGAGTGTGAGGAGGACGAGTTTCCCTGCCAGAATGGCTACTGCATCCGGAGTC TGTGGCACTGCGATGGTGACAATGACTGTGGCGACAACAGCGATGAGCAGTGTGACATGC GCAAGTGCTCCGACAAGGAGTTCCGCTGTAGTGACGGAAGCTGCATTGCTGAGCATTGGT ACTGCGACGGTGACACCGACTGCAAAGATGGCTCCGATGAGGAGAACTGTCCCTCAGCAG TGCCAGCGCCCCCCTGCAACCTGGAGGAGTTCCAGTGTGCCTATGGACGCTGCATCCTCG ACATCTACCACTGCGATGGCGACGATGACTGTGGAGACTGGTCAGACGAGTCTGACTGCT CCTCCCACCAGCCCTGCCGCTCTGGGGAGTTCATGTGTGACAGTGGCCTGTGCATCAATG CAGGCTGGCGCTGCGATGGTGACGCGGACTGTGATGACCAGTCTGATGAGCGCAACTGCA CCACCTCCATGTGTACGGCAGAACAGTTCCGCTGTCACTCAGGCCGCTGTGTCCGCCTGT CCTGGCGCTGTGATGGGGAGGACGACTGTGCAGACAACAGCGATGAAGAGAACTGTGAGA ATACAGGAAGCCCCCAATGTGCCTTGGACCAGTTCCTGTGTTGGAATGGGCGCTGCATTG GGCAGAGGAAGCTGTGCAACGGGGTCAACGACTGTGGTGACAACAGCGACGAAAGCCCAC AGCAGAATTGCCGGCCCCGGACGGGTGAGGAGAACTGCAATGTTAACAACGGTGGCTGTG CCCAGAAGTGCCAGATGGTGCGGGGGGCAGTGCAGTGTACCTGCCACACAGGCTACCGGC TCACAGAGGATGGGCACACGTGCCAAGATGTGAATGAATGTGCCGAGGAGGGGTATTGCA GCCAGGGCTGCACCAACAGCGAAGGGGCTTTCCAATGCTGGTGTGAAACAGGCTATGAAC TACGGCCCGACCGGCGCAGCTGCAAGGCTCTGGGGCCAGAGCCTGTGCTGCTGTTCGCCA ATCGCATCGACATCCGGCAGGTGCTGCCACACCGCTCTGAGTACACACTGCTGCTTAACA ACCTGGAGAATGCCATTGCCCTTGATTTCCACCACCGCCGCGAGCTTGTCTTCTGGTCAG ATGTCACCCTGGACCGGATCCTCCGTGCCAACCTCAACGGCAGCAACGTGGAGGAGGTTG TGTCTACTGGGCTGGAGAGCCCAGGGGGCCTGGCTGTGGATTGGGTCCATGACAAACTCT ACTGGACCGACTCAGGCACCTCGAGGATTGAGGTGGCCAATCTGGACGGGGCCCACCGGA AGGTGTTGCTGTGGCAGAACCTGGAGAAGCCCCGGGCCATTGCCTTGCATCCCATGGAGG GTACCATTTACTGGACAGACTGGGGCAACACCCCCCGTATTGAGGCCTCCAGCATGGATG GCTCTGGACGCCGCATCATTGCCGATACCCATCTCTTCTGGCCCAATGGCCTCACCATCG ACTATGCCGGGCGCCGTATGTACTGGGTGGATGCTAAGCACCATGTCATCGAGAGGGCCA ATCTGGATGGGAGTCACCGTAAGGCTGTCATTAGCCAGGGCCTCCCGCATCCCTTCGCCA TCACAGTGTTTGAAGACAGCCTGTACTGGACAGACTGGCACACCAAGAGCATCAATAGCG CTAACAAATTTACGGGGAAGAACCAGGAAATCATTCGCAACAAACTCCACTTCCCTATGG ACATCCACACCTTGCACCCCCAGCGCCAACCTGCAGGGAAAAACCGCTGTGGGGACAACA ACGGAGGCTGCACGCACCTGTGTCTGCCCAGTGGCCAGAACTACACCTGTGCCTGCCCCA CTGGCTTCCGCAAGATCAGCAGCCACGCCTGTGCCCAGAGTCTTGACAAGTTCCTGCTTT TTGCCCGAAGGATGGACATCCGTCGAATCAGCTTTGACACAGAGGACCTGTCTGATGATG TCATCCCACTGGCTGACGTGCGCAGTGCTGTGGCCCTTGACTGGGACTCCCGGGATGACC ACGTGTACTGGACAGATGTCAGCACTGATACCATCAGCAGGGCCAAGTGGGATGGAACAG GACAGGAGGTGGTAGTGGATACCAGTTTGGAGAGCCCAGCTGGCCTGGCCATTGATTGGG TCACCAACAAACTGTACTGGACAGATGCAGGTACAGACCGGATTGAAGTAGCCAACACAG ATGGCAGCATGAGAACAGTACTCATCTGGGAGAACCTTGATCGTCCTCGGGACATCGTGG TGGAACCCATGGGCGGGTACATGTATTGGACTGACTGGGGTGCGAGCCCCAAGATTGAAC GAGCTGGCATGGATGCCTCAGGCCGCCAAGTCATTATCTCTTCTAATCTGACCTGGCCTA ATGGGTTAGCTATTGATTATGGGTCCCAGCGTCTATACTGGGCTGACGCCGGCATGAAGA CAATTGAATTTGCTGGACTGGATGGCAGTAAGAGGAAGGTGCTGATTGGAAGCCAGCTCC CCCACCCATTTGGGCTGACCCTCTATGGAGAGCGCATCTATTGGACTGACTGGCAGACCA AGAGCATACAGAGCGCTGACCGGCTGACAGGGCTGGACCGGGAGACTCTGCAGGAGAACC TGGAAAACCTAATGGACATCCATGTCTTCCACCGCCGCCGGCCCCCAGTGTCTACACCAT GTGCTATGGAGAATGGCGGCTGTAGCCACCTGTGTCTTAGGTCCCCAAATCCAAGCGGAT TCAGCTGTACCTGCCCCACAGGCATCAACCTGCTGTCTGATGGCAAGACCTGCTCACCAG GCATGAACAGTTTCCTCATCTTCGCCAGGAGGATAGACATTCGCATGGTCTCCCTGGACA TCCCTTATTTTGCTGATGTGGTGGTACCAATCAACATTACCATGAAGAACACCATTGCCG TTGGAGTAGACCCCCAGGAAGGAAAGGTGTACTGGTCTGACAGCACACTGCACAGGATCA GTCGTGCCAATCTGGATGGCTCACAGCATGAGGACATCATCACCACAGGGCTACAGACCA CAGATGGGCTCGCGGTTGATGCCATTGGCCGGAAAGTATACTGGACAGACACGGGAACAA ACCGGATTGAAGTGGGCAACCTGGACGGGTCCATGCGGAAAGTGTTGGTGTGGCAGAACC TTGACAGTCCCCGGGCCATCGTACTGTACCATGAGATGGGGTTTATGTACTGGACAGACT GGGGGGAGAATGCCAAGTTAGAGCGGTCCGGAATGGATGGCTCAGACCGCGCGGTGCTCA TCAACAACAACCTAGGATGGCCCAATGGACTGACTGTGGACAAGGCCAGCTCCCAACTGC TATGGGCCGATGCCCACACCGAGCGAATTGAGGCTGCTGACCTGAATGGTGCCAATCGGC ATACATTGGTGTCACCGGTGCAGCACCCATATGGCCTCACCCTGCTCGACTCCTATATCT ACTGGACTGACTGGCAGACTCGGAGCATCCACCGTGCTGACAAGGGTACTGGCAGCAATG TCATCCTCGTGAGGTCCAACCTGCCAGGCCTCATGGACATGCAGGCTGTGGACCGGGCAC AGCCACTAGGTTTTAACAAGTGCGGCTCGAGAAATGGCGGCTGCTCCCACCTCTGCTTGC CTCGGCCTTCTGGCTTCTCCTGTGCCTGCCCCACTGGCATCCAGCTGAAGGGAGATGGGA AGACCTGTGATCCCTCTCCTGAGACCTACCTGCTCTTCTCCAGCCGTGGCTCCATCCGGC GTATCTCACTGGACACCAGTGACCACACCGATGTGCATGTCCCTGTTCCTGAGCTCAACA ATGTCATCTCCCTGGACTATGACAGCGTGGATGGAAAGGTCTATTACACAGATGTGTTCC TGGATGTTATCAGGCGAGCAGACCTGAACGGCAGCAACATGGAGACAGTGATCGGGCGAG GGCTGAAGACCACTGACGGGCTGGCAGTGGACTGGGTGGCCAGGAACCTGTACTGGACAG ACACAGGTCGAAATACCATTGAGGCGTCCAGGCTGGATGGTTCCTGCCGCAAAGTACTGA TCAACAATAGCCTGGATGAGCCCCGGGCCATTGCTGTTTTCCCCAGGAAGGGGTACCTCT TCTGGACAGACTGGGGCCACATTGCCAAGATCGAACGGGCAAACTTGGATGGTTCTGAGC GGAAGGTCCTCATCAACACAGACCTGGGTTGGCCCAATGGCCTTACCCTGGACTATGATA CCCGCAGGATCTACTGGGTGGATGCGCATCTGGACCGGATCGAGAGTGCTGACCTCAATG GGAAACTGCGGCAGGTCTTGGTCGGCCATGTGTCCCACCCCTTTGCCCTCACACAGCAAG ACAGGTGGATCTACTGGACAGACTGGCAGACCAAGTCAATCCAGCGTGTTGACAAATACT CAGGCCGGAACAAGGAGACAGTGCTGGCAAATGTGGAAGGACTCATGGATATCATCGTGG TTTCCCCTCAGCGGCAGACAGGGACCAATGCCTGTGGTGTGAACAATGGTGGCTGCACCC ACCTCTGCTTTGCCAGAGCCTCGGACTTCGTATGTGCCTGTCCTGACGAACCTGATAGCC AGCCCTGCTCCCTTGTGCCTGGCCTGGTACCACCAGCTCCTAGGGCTACTGGCATGAGTG AAAAGAGCCCAGTGCTACCCAACACACCACCTACCACCTTGTATTCTTCAACCACCCGGA CCCGCACGTCTCTGGAGGAGGTGGAAGGAAGATGCTCTGAAAGGGATGCCAGGCTGGGCC TCTGTGCACGTTCCAATGACGCTGTTCCTGCTGCTCCAGGGGAAGGACTTCATATCAGCT ACGCCATTGGTGGACTCCTCAGTATTCTGCTGATTTTGGTGGTGATTGCAGCTTTGATGC TGTACAGACACAAAAAATCCAAGTTCACTGATCCTGGAATGGGGAACCTCACCTACAGCA ACCCCTCCTACCGAACATCCACACAGGAAGTGAAGATTGAAGCAATCCCCAAACCAGCCA TGTACAACCAGCTGTGCTATAAGAAAGAGGGAGGGCCTGACCATAACTACACCAAGGAGA AGATCAAGATCGTAGAGGGAATCTGCCTCCTGTCTGGGGATGATGCTGAGTGGGATGACC TCAAGCAACTGCGAAGCTCACGGGGGGGCCTCCTCCGGGATCATGTATGCATGAAGACAG ACACGGTGTCCATCCAGGCCAGCTCTGGCTCCCTGGATGACACAGAGACGGAGCAGCTGT TACAGGAAGAGCAGTCTGAGTGTAGCAGCGTCCATACTGCAGCCACTCCAGAAAGACGAG GCTCTCTGCCAGACACGGGCTGGAAACATGAACGCAAGCTCTCCTCAGAGAGCCAGGTCT AAATGCCCACATTCTCTTCCCTGCCTGCCTGTTCCTTCTCCTTTATGGACGTCTAGTCCT TGTGCTCGCTTACACCGCAGGCCCCGCTTCTGTGTGCTTGTCCTCCTCCTCCTCCCACCC CATAACTGTTCCTAAGCCTTCACCGGAGCTGTTTACCACGTGAGTCCATAACTACCTGTG CACAAGAAATGATGGCACATCACGAGAATTTAGACCTGGATTTTACCATGAACCTCACAT CTTGTACTCCATCCTGGGCCCCCTGAAACTGCTTATTCGTGATTCCTCACCAGCGTAGAG CTCCACCTCCCCTTTCCCCAGTACCCTCAGTGCCTGCTTCTCAGTGCTGATGCAGCTGAT GACCCAGGACTGCGCTCTGCCCCATCACAGCCAGCATGACTGCTTCTCTGAGAGAACTTG CCCATCAGGGGCTGGGACATGGGGGTGTGGGTAAAGACAGGGATGAAGGATAGAGGCTGA GAGAAGAAGGAAGAATCAGCCCAGCAGGTATGGGCATCTGGGAAACCTCCAGCCTCAAGT GTGTTGGTAACATGAAAAAGCTCTGGGGGGTAGTTGGATCTGGGTGTCTGGTCCATTGCT GGCAGTGGACATTATTCTTGCCCTAAGAGACACTGCCTTTTCAGCAGCAGATACTGGTGA GATGGGGGTGGCTCAGGCTGTTCTTCCTCCTCCTAGAATGTCTGGAGCTGTTTCTACATT CAGATAACTGGGTCCCCTATCACAAGGCTACTGGCTAATAGG |
| Restriction Sites | Please inquire |
| ACCN | NM_002334 |
| Insert Size | 6600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain 3 SNPs compared with NM_002334.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002334.1, NP_002325.1 |
| RefSeq Size | 8076 bp |
| RefSeq ORF | 5718 bp |
| Locus ID | 4038 |
| UniProt ID | O75096 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Characterization of the Interaction of Sclerostin with the Low Density Lipoprotein Receptor-related Protein (LRP) Family of Wnt Co-receptors
,Gill Holdsworth, Patrick Slocombe, Carl Doyle, Bernadette Sweeney, Vaclav Veverka, Kelly Le Riche, Richard J. Franklin, Joanne Compson, Daniel Brookings, James Turner, Jeffery Kennedy, Rachael Garlish, Jiye Shi, Laura Newnham, David McMillan, Mariusz Muzylak, Mark D. Carr, Alistair J. Henry, Thomas Ceska, and Martyn K. Robinson,
J. Biol. Chem., Aug 2012; 287: 26464 - 26477.
[LRP4]
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