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ZNF451 (NM_001031623) Human Untagged Clone
CAT＃: SC302520
ZNF451 (untagged)-Human zinc finger protein 451 (ZNF451), transcript variant 1
CNY 20,430.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | COASTER; dJ417I1.1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC302520 representing NM_001031623.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGAGACCCGGGGTCGGAGATAATAGAATCTGTCCCTCCAGCTGGCCCTGAGGCATCTGAGTCAACA ACGGATGAAAATGAAGACGACATTCAGTTTGTCAGTGAAGGACCATTACGACCTGTTCTTGAATACATT GATCTGGTCAGCAGTGATGATGAAGAGCCTAGCACCTCTTATACTGATGAGAATATTAAACGTAAAGAC CATATTGATTATCAGAAGGATAAAGTTGCTTTAACTCTGGCTCGTCTAGCCCGCCATGTTGAAGTGGAG AAACAGCAGAAAGAAGAGAAGAATAGAGCATTCAGAGAAAAAATTGATTTTCAGCATGCTCATGGGTTA CAAGAATTGGAATTTATTCGAGGACATTCTGATACAGAAGCAGCAAGACTGTGTGTGGACCAGTGGCTA AAAATGCCAGGACTCAAAACAGGCACAATTAATTGTGGAACAAAAAGTTCATTCCGAAGAGGAGGCCAC ACGTGGGTGTCTGGGAAACCAATTTTATGTCCTATAATGCACTGTAACAAGGAGTTTGACAATGGGCAC CTTCTCTTAGGACATTTGAAAAGGTTCGATCACTCTCCATGTGATCCAACAATTACACTACATGGACCT TTCTTCAGCTCCTTTGCTTGTGTAGTATGTTATAAAAAATTTGTTACTCAACAACAATATAGAGATCAC CTTTTTGATAAGGAAGCCACAGATGATGGACATAACAACAACCTTCTTCCTCAGATTATTCAGTGTTTT GCATGTCCAAATTGCTTCCTTCTTTTTAGCAGAAAGGAGGAGTGTTCAAAGCATATGTCTGGAAAGAAT CATTTCCATCAGAGTTTCAAACTGGGTGATAACAAAGGAATTGCACATCCAATATCTTTCCCATCTTTT GCAAAGAAACTTTTGATCTCTCTGTGCAAAGATGTTCCCTTTCAAGTTAAGTGTGTGGCCTGCCACAAG ACACTGCGTTCCCACATGGAGCTCACTGCCCATTTCAGAGTTCATTGTCGAAATGCTGGACCTGTAGCT GTAGCTGAGAAGAGCATTACCCAGGTTGCAGAGAAATTCATATTAAGAGGTTATTGTCCAGATTGCAAT CAAGTCTTTGTGGATGAAACCAGCACCCAAAATCATAAGCAGAATTCAGGACACAAAGTCCGAGTCATT AACTCAGTGGAAGAATCAGTCTTACTCTATTGCCACAGCAGCGAAGGGAACAAGGATCCTTCTTCTGAC TTGCATTTATTGTTGGATCAATCAAAATTTTCATCACTTAAAAGAACCATGTCTATTAAAGAATCTAGC TCACTGGAGTGCATTGCCATTCCAAAAAAGAAGATGAATTTAAAAGATAAAAGCCATGAAGGTGTTGCT TGTGTCCAGAAAGAAAAATCAGTAGTTAAAACCTGGTTCTGTGAATGCAATCAGCGATTCCCAAGTGAA GATGCAGTAGAAAAGCATGTTTTCTCAGCAAACACAATGGGTTATAAATGTGTGGTCTGTGGAAAGGTA TGTGATGATTCAGGGGTCATTCGTTTACACATGAGCCGGATTCACGGAGGGGCACATTTAAATAACTTT CTTTTCTGGTGTCGGACATGCAAAAAGGAGTTAACAAGGAAAGATACTATCATGGCACATGTGACTGAA TTTCATAATGGACACAGATATTTTTATGAGATGGATGAGGTAGAAGGTGAAACTTTGCCATCATCCTCT ACAACATTGGATAATTTGACTGCTAACAAGCCTTCATCAGCTATTACTGTTATTGATCATTCCCCGGCA AATAGTTCTCCGAGGGGTAAATGGCAATGCCGGATTTGTGAAGATATGTTTGATTCCCAGGAATATGTA AAACAGCACTGCATGTCTTTGGCAAGCCACAAGTTTCATAGATACAGCTGTGCTCACTGCAGAAAGCCT TTTCATAAGATAGAAACATTGTACCGACATTGCCAAGATGAGCATGACAATGAGATAAAGATTAAATAC TTCTGTGGGCTTTGTGATCTTATCTTTAATGTGGAAGAAGCATTTCTGAGTCATTATGAGGAGCACCAC AGCATAGATTATGTATTTGTGTCAGAAAAAACTGAAACTTCAATTAAAACCGAAGATGATTTTCCAGTA ATAGAGACCAGTAACCAGTTAACTTGTGGTTGCCGTGAGAGTTACATCTGTAAAGTCAACAGAAAAGAA GATTATAGCAGATGTCTCCAAATCATGCTGGATAAAGGAAAACTGTGGTTTCGCTGCAGTTTATGTTCG GCAACAGCACAGAATTTAACCGACATGAACACTCATATCCATCAAGTGCACAAAGAAAAGAGTGATGAG GAGGAGCAGCAGTATGTAATCAAGTGTGGCACCTGCACCAAAGCATTTCATGATCCTGAGAGTGCACAG CAGCATTTCCATAGAAAACATTGCTTCTTACAGAAACCCAGTGTGGCTCATTTTGGATCTGAAAAATCA AACCTGTACAAGTTTACTGCTAGTGCCTCACATACAGAGAGAAAACTGAAACAGGCAATAAACTATTCA AAAAGTTTAGACATGGAGAAAGGAGTTGAGAATGACCTAAGCTATCAGAATATAGAGGAAGAAATTGTT GAGCTTCCAGATTTGGATTACCTGCGAACCATGACTCATATAGTCTTTGTAGATTTTGATAACTGGTCA AACTTTTTTGGTCATCTACCAGGGCATCTAAACCAAGGAACATTTATTTGGGGCTTTCAAGGAGGAAAC ACCAATTGGAAGCCTCCGCTCAACTGTAAGATTTATAACTACCTGAACAGGATTGGATGCTTCTTCCTT CATCCTCGCTGTAGTAAAAGAAAAGATGCTGCTGATTTTGCCATATGTATGCATGCTGGCCGTCTAGAT GAACAACTACCCAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAAT CAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACTTAGAGGGAGATATGATGTGT GCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAACATGGGTGCCAAAAAT ACTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTT GAGGAAATGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001031623 |
| Insert Size | 3186 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001031623.2 |
| RefSeq Size | 5241 bp |
| RefSeq ORF | 3186 bp |
| Locus ID | 26036 |
| UniProt ID | Q9Y4E5 |
| Protein Families | Transcription Factors |
| MW | 121.5 kDa |
| Gene Summary | E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215720 | ZNF451 (Myc-DDK-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 1 |
CNY 7,392.00 |
|
| RC215720L1 | Lenti-ORF clone of ZNF451 (Myc-DDK-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 1 |
CNY 9,792.00 |
|
| RC215720L2 | Lenti-ORF clone of ZNF451 (mGFP-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 1 |
CNY 13,110.00 |
|
| RC215720L3 | Lenti-ORF clone of ZNF451 (Myc-DDK-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 1 |
CNY 13,110.00 |
|
| RC215720L4 | Lenti-ORF clone of ZNF451 (mGFP-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 1 |
CNY 13,110.00 |
|
| RG215720 | ZNF451 (tGFP-tagged) - Human zinc finger protein 451 (ZNF451), transcript variant 1 |
CNY 12,350.00 |
