SH3BP5 (NM_001018009) Human Untagged Clone
CAT#: SC302123
SH3BP5 (untagged)-Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2
CNY 6,270.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | SAB; SH3BP-5 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC302123 representing NM_001018009.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCTGAATCACGCCACTCAGAGGGTCATGGAGGCGGAGCAGACCAAGACCAGGAGCGAGCTGGTGCAT AAGGAGACGGCAGCCAGGTACAATGCCGCCATGGGCCGCATGCGACAGCTGGAGAAGAAACTCAAGAGA GCCATCAACAAGTCCAAGCCTTATTTTGAACTCAAGGCAAAGTACTATGTGCAGCTCGAGCAACTGAAA AAGACTGTGGATGACCTGCAGGCCAAACTGACCCTGGCAAAAGGCGAGTACAAGATGGCCCTGAAGAAC CTGGAGATGATCTCAGATGAGATCCACGAGCGGCGGCGCTCCAGTGCCATGGGGCCTCGGGGATGCGGT GTTGGTGCTGAGGGCAGCAGCACATCTGTGGAGGATCTGCCAGGGAGCAAACCTGAGCCTGATGCCATT TCTGTGGCCTCGGAGGCCTTTGAAGATGACAGCTGTAGCAACTTTGTGTCTGAAGATGACTCGGAAACC CAGTCCGTGTCCAGCTTTAGTTCAGGACCAACAAGCCCGTCTGAGATGCCTGACCAGTTCCCTGCGGTT GTGAGGCCTGGCAGCCTGGATCTGCCCAGCCCTGTGTCCCTGTCAGAGTTTGGGATGATGTTCCCAGTG TTGGGCCCTCGAAGTGAATGCAGCGGGGCCTCCTCCCCTGAATGTGAAGTAGAACGAGGAGACAGGGCA GAAGGGGCAGAGAATAAAACAAGTGACAAAGCCAACAACAACCGGGGCCTCAGCAGTAGCAGTGGCAGT GGTGGCAGCAGTAAGAGCCAAAGCAGCACCTCCCCTGAGGGCCAGGCCTTGGAGAACCGGATGAAGCAG CTCTCCCTACAGTGCTCAAAGGGAAGAGATGGAATTATTGCTGACATAAAAATGGTGCAGATTGGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001018009 |
Insert Size | 897 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001018009.3 |
RefSeq Size | 3203 bp |
RefSeq ORF | 897 bp |
Locus ID | 9467 |
UniProt ID | O60239 |
MW | 32.2 kDa |
Gene Summary | Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (PubMed:26506309, PubMed:30217979). Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, uses an alternate internal splice site and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC221321 | SH3BP5 (Myc-DDK-tagged)-Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2 |
CNY 3,656.00 |
|
RC221321L1 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
RC221321L2 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RC221321L3 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC221321L4 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RG221321 | SH3BP5 (tGFP-tagged) - Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2 |
CNY 5,256.00 |