GCN2 (EIF2AK4) (NM_001013703) Human Untagged Clone
CAT#: SC301871
EIF2AK4 (untagged)-Human eukaryotic translation initiation factor 2 alpha kinase 4 (EIF2AK4)
CNY 11,288.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | GCN2; PVOD2 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_001013703 edited
GGCGCAGCGCTGCCATGGCTGGGGGCCGTGGGGCCCCCGGGCGCGGCCGGGACGAGCCTC CGGAGAGCTACCCGCAACGACAGGACCACGAGCTACAGGCCCTGGAGGCCATCTACGGCG CGGACTTCCAAGACCTGCGGCCGGACGCTTGCGGACCGGTCAAAGAGCCCCCTGAAATCA ATTTAGTTTTGTACCCTCAAGGCCTAACTGGTGAAGAAGTATATGTAAAAGTGGATTTGA GGGTTAAATGCCCACCTACCTATCCAGATGTAGTTCCTGAAATAGAGTTAAAAAATGCCA AAGGTCTATCAAATGAAAGTGTCAATTTGTTAAAATCTCGCCTAGAAGAACTGGCCAAGA AACACTGTGGGGAGGTGATGATCTTTGAACTGGCTTACCACGTGCAGTCATTTCTCAGCG AGCATAACAAGCCCCCTCCCAAGTCTTTTCATGAAGAAATGCTGGAAAGGCGGGCTCAGG AGGAGCAGCAGAGGCTGTTGGAGGCCAAGCGGAAAGAAGAGCAGGAGCAACGTGAAATCC TGCATGAGATTCAGAGAAGGAAAGAAGAGATAAAAGAAGAGAAAAAAAGGAAAGAAATGG CTAAGCAGGAACGTTTGGAAATTGCTAGTTTGTCAAACCAAGATCATACCTCTAAGAAGG ACCCAGGAGGACACAGAACGGCTGCCATTCTACATGGAGGCTCTCCTGACTTTGTAGGAA ATGGTAAACATCGGGCAAACTCCTCAGGAAGGTCTAGGCGAGAACGTCAGTATTCTGTAT GTAATAGTGAAGATTCTCCTGGCTCTTGTGAAATTCTGTATTTCAATATGGGGAGTCCTG ATCAGCTCATGGTGCACAAAGGGAAATGTATTGGCAGTGATGAACAACTTGGAAAATTAG TCTACAATGCTTTGGAAACAGCCACTGGTGGCTTTGTCTTGTTGTATGAGTGGGTCCTTC AGTGGCAGAAAAAAATGGGTCCATTCCTTACCAGTCAAGAAAAAGAGAAGATTGATAAGT GCAAAAAGCAGATTCAAGGAACAGAAACAGAATTCAACTCACTGGTAAAATTGAGCCATC CAAATGTAGTACGCTACCTTGCAATGAATCTCAAAGAGCAAGACGACTCCATCGTGGTGG ACATTTTAGTGGAGCACATTAGTGGGGTCTCTCTTGCTGCACACCTGAGCCACTCAGGCC CCATCCCTGTGCATCAGCTTCGCAGGTACACAGCTCAGCTCCTGTCAGGCCTTGATTATC TGCACAGCAATTCTGTGGTGCATAAGGTCCTGAGTGCATCTAATGTCTTGGTGGATGCAG AAGGCACCGTCAAGATTACGGACTATAGCATTTCTAAGCGCCTCGCAGACATTTGCAAGG AGGATGTGTTTGAGCAAACCCGAGTTCGTTTTAGTGACAATGCTCTGCCTTATAAAACGG GGAAGAAAGGAGATGTTTGGCGTCTTGGCCTTCTGCTGCTGTCCCTCAGCCAAGGACAGG AATGTGGAGAGTACCCTGTGACCATCCCTAGTGACTTACCAGCTGACTTTCAAGATTTTC TAAAGAAATGTGTGTGCTTGGATGACAAGGAAAGATGGAGTCCCCAGCAGTTGTTGAAAC ACAGCTTTATAAATCCCCAGCCAAAAATGCCTCTAGTGGAACAAAGTCCTGAAGATTCTG AAGGACAAGATTATGTTGAGACTGTTATTCCTAGCAACCGGCTACCCAGTGCTGCCTTCT TTAGTGAGACACAGAGACAGTTTTCCCGATACTTCATTGAGTTTGAAGAATTACAACTTC TTGGTAAAGGAGCTTTTGGAGCTGTCATCAAGGTGCAGAACAAGTTGGACGGCTGCTGCT ACGCAGTGAAGCGCATCCCCATCAACCCGGCCAGCCGGCAGTTCCGCAGGATCAAGGGCG AAGTGACACTGCTGTCACGGCTGCACCATGAGAACATTGTGCGCTACTACAACGCCTGGA TCGAGCGGCACGAGCGGCCGGCGGGACCGGGGACGCCGCCCCCGGACTCCGGGCCCCTGG CCAAGGATGACCGAGCTGCACGCGGGCAGCCGGCGAGCGACACAGACGGCCTGGACAGCG TAGAGGCCGCCGCGCCGCCACCCATCCTCAGCAGCTCGGTGGAGTGGAGCACTTCGGGCG AGCGCTCGGCCAGTGCCCGTTTCCCCGCCACCGGCCCGGGCTCCAGCGATGACGAGGACG ACGACGAGGACGAGCACGGTGGCGTCTTCTCCCAGTCCTTCCTGCCTGCTTCAGATTCTG AAAGTGATATTATCTTTGACAATGAAGATGAGAACAGTAAAAGTCAGAATCAGGATGAAG ATTGCAATGAAAAGAATGGCTGCCATGAAAGTGAGCCATCAGTGACGACTGAGGCTGTGC ACTACCTATACATCCAGATGGAGTACTGTGAGAAGAGCACTTTACGAGACACCATTGACC AGGGACTGTATCGAGACACCGTCAGACTCTGGAGGCTTTTTCGAGAGATTCTGGATGGAT TAGCTTATATCCATGAGAAAGGAATGATTCACCGGGATTTGAAGCCTGTCAACATTTTTT TGGATTCTGATGACCATGTGAAAATAGGTGATTTTGGTTTGGCGACAGACCATCTAGCCT TTTCTGCTGACAGCAAACAAGACGATCAGACAGGAGACTTGATTAAGTCAGACCCTTCAG GTCACTTAACTGGGATGGTTGGCACTGCTCTCTATGTAAGCCCAGAGGTCCAAGGAAGCA CCAAATCTGCATACAACCAGAAAGTGGATCTCTTCAGCCTGGGAATTATCTTCTTTGAGA TGTCCTATCACCCCATGGTCACGGCTTCAGAAAGGATCTTTGTTCTCAACCAACTCAGAG ATCCCACTTCGCCTAAGTTTCCAGAAGACTTTGACGATGGAGAGCATGCAAAGCAGAAAT CAGTCATCTCCTGGCTGTTGAACCACGATCCAGCAAAACGGCCCACAGCCACAGAACTGC TCAAGAGTGAGCTGCTGCCCCCACCCCAGATGGAGGAGTCAGAGCTGCATGAAGTGCTGC ACCACACGCTGACCAACGTGGATGGGAAGGCCTACCGCACCATGATGGCCCAGATCTTCT CGCAGCGCATCTCCCCTGCCATCGATTACACCTATGACAGCGACATACTGAAGGGCAACT TCTCAATCCGTACAGCCAAGATGCAGCAGCATGTGTGTGAAACCATCATCCGCATCTTTA AAAGACATGGAGCTGTTCAGTTGTGTACTCCACTACTGCTTCCCCGAAACAGACAAATAT ATGAGCACAACGAAGCTGCCCTATTCATGGACCACAGCGGGATGCTGGTGATGCTTCCTT TTGACCTGCGGATCCCTTTTGCAAGATATGTGGCAAGAAATAATATATTGAATTTAAAAC GATACTGCATAGAACGTGTGTTCAGGCCGCGCAAGTTAGATCGATTTCATCCCAAAGAAC TTCTGGAGTGTGCATTTGATATTGTCACTTCTACCACCAACAGCTTTCTGCCCACTGCTG AAATTATCTACACTATCTATGAAATCATCCAAGAGTTTCCAGCACTTCAGGAAAGAAATT ACAGTATTTATTTGAACCATACCATGTTATTGAAAGCAATACTCTTACACTGTGGGATCC CAGAAGATAAACTCAGTCAAGTCTACATTATTCTGTATGATGCTGTGACAGAGAAGCTGA CGAGGAGAGAAGTGGAAGCTAAATTTTGTAATCTGTCTTTGTCTTCTAATAGTCTGTGTC GACTCTACAAGTTTATTGAACAGAAGGGAGATTTGCAAGATCTTATGCCAACAATAAATT CATTAATAAAACAGAAAACAGGTATTGCACAGTTGGTGAAGTATGGCTTAAAAGACCTAG AGGAGGTTGTTGGACTGTTGAAGAAACTCGGCATCAAGTTACAGGTCTTGATCAATTTGG GCTTGGTTTACAAGGTGCAGCAGCACAATGGAATCATCTTCCAGTTTGTGGCTTTCATCA AACGAAGGCAAAGGGCTGTACCTGAAATCCTCGCAGCTGGAGGCAGATATGACCTGCTGA TTCCCCAGTTTAGAGGGCCACAAGCTCTGGGGCCAGTTCCCACTGCCATTGGGGTCAGCA TAGCTATAGACAAGATATCTGCTGCTGTCCTCAACATGGAGGAATCTGTTACAATAAGCT CTTGTGACCTCCTGGTTGTAAGTGTTGGCCAGATGTCTATGTCCAGGGCCATCAACCTAA CCCAGAAACTCTGGACAGCAGGCATCACAGCAGAAATCATGTACGACTGGTCACAGTCCC AAGAGGAATTACAAGAGTACTGCAGACATCATGAAATCACCTATGTGGCCCTTGTCTCGG ATAAAGAAGGAAGCCATGTCAAGGTTAAGTCTTTCGAGAAGGAAAGGCAGACAGAGAAGC GTGTGCTGGAGACTGAACTTGTGGACCATGTACTGCAGAAACTGAGGACTAAAGTCACTG ATGAAAGGAATGGCAGAGAAGCTTCCGATAATCTTGCAGTGCAAAATCTGAAGGGGTCAT TTTCTAATGCTTCAGGTTTGTTTGAAATCCATGGAGCAACAGTGGTTCCCATTGTGAGTG TGCTAGCCCCGGAGAAGCTGTCAGCCAGCACTAGGAGGCGCTATGAAACTCAGGTACAAA CTCGACTTCAGACCTCCCTTGCCAACTTACATCAGAAAAGCAGTGAAATTGAAATTCTGG CTGTGGATCTACCCAAAGAAACAATATTACAGTTTTTATCATTAGAGTGGGATGCTGATG AACAGGCATTTAACACAACTGTGAAGCAGCTGCTGTCACGCCTGCCAAAGCAAAGATACC TCAAATTAGTCTGTGATGAAATTTATAACATCAAAGTAGAAAAAAAGGTGTCTGTGCTAT TTCTGTACAGCTATAGAGATGACTACTACAGAATCTTATTTTAACCCTGAAGAACTGTCA TTAACCTCATTCAAACAGACAGAGGCTTATACTGGAATAATGGAATGTTGTACATTCATC ATAATTTAAAATTAAATTCTAAGAAGAGGCTGGGTGCAGTGGCTCACACCTTTAATCCCA GCACTTTGGGAAGCCAAGGCAGGAAGACTGCTTGAAACCAGGAGTTTGAGACCAGCCTGA GCAACAAAGCAAGACCCCATCTCTATAAAAACTAAAAAAATTAGTTGGGCATGGTGGCAC ATGCCTGTAGTCCCAGCTACTCCAGAGGCTGAGATGGATCATCTGAGCCTCAGGAGGTTG AGGCTGCAGTGAGCTGTGACTGCGCCACTGCACTCCAGTCTGGGACAACAGAGCAAGACC CTGTCTTAAAAAAAAAAAGAAAAAAAAATTTTTTTTCTAAGAAGCTGTCCTACAAAGTTG AGCTTTGTTAGTTTTTCATGTGTAATATATTATAAATTTATCTTTTGGGATATAATAAAT GCTTTCATATAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001013703 unedited
AGTTCNCATTTGTATACCACTCATATAGGCGGCCGCGNAATTCGCACGAGGCGCAGCGCT GCCATGGCTGGGGGCCGTGGGGCCCCCGGGCGCGGCCGGGACGAGCCTCCGGAGAGCTAC CCGCAACGACAGGACCACGAGCTACAGGCCCTGGAGGCCATCTACGGCGCGGACTTCCAA GACCTGCGGCCGGACGCTTGCGGACCGGTCAAAGAGCCCCCTGAAATCAATTTAGTTTTG TACCCTCAAGGCCTAACTGGTGAAGAAGTATATGTAAAAGTGGATTTGAGGGTTAAATGC CCACCTACCTATCCAGATGTAGTTCCTGAAATAGAGTTAAAAAATGCCAAAGGTCTATCA AATGAAAGTGTCAATTTGTTAAAATCTCGCCTAGAAGAACTGGCCAAGAAACACTGTGGG GAGGTGATGATCTTTGAACTGGCTTACCACGTGCAGTCATTTCTCAGCGAGCATAACAAG CCCCCTCCCAAGTCTTTTCATGAAGAAATGCTGGAAAGGCGGGCTCAGGAGGAGCAGCAG AGGCTGTTGGAGGCCAAGCGGANAGAAGAGCAGGAGCAACGTGAAATCCTGCATGAGATT CAGAGAAGGAAAGAAGAAGATAAAGAAGAGAANAAAAGGAAGAAATGGCTAAGCAAGAAC GTTTGAAAATTGCTAGTTTGTCAAACCAAGATCATACCTCTAAGAAGGACCCAGNAGGAC ACAGAACGGCTGCCAATCTACATGGAAGCTCTCCTGACCTTGTAGGAAATGGTAAACATC GGGGCANAACTCTCAGGAAAGTCCTAGCCGAGAACGTCAGTAATCTGTAATGTAAAGTGA AAGATNCTCCTGCCTCTTGGGAAAATCCTGTTTTTAATATGGGGAGTCCCTGATTAGCTC ATGGGTGCCCAAAGGGAAT >OriGene 3' read for NM_001013703 unedited
NCCCCATTGGANGATGGCACTTCCCAGGNCCAGGNANGAGCACTGGNGGNAGGGGTCACA GGGNATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTC GAGTTTTTTTTTTTTTTTTTTATATGAAAGCATTTATTATATCCCAAAAGATAAATTTAT AATATATTACACATGAAAAACTAACAAAGCTCAACTTTGTAGGACAGCTTCTTAGAAAAA AAATTTTTTTTTCTTTTTTTTTTTAAGACAGGGTCTTGCTCTGTTGTCCCAGACTGGAGT GCAGTGGCGCAGTCACAGCTCACTGCAGCCTCAACCTCCTGAGGCTCAGATGATCCATCT CAGCCTCTGGAGTAGCTGGGACTACAGGCATGTGCCACCATGCCCAACTAATTTTTTTAG TTTTTATAGAGATGGGGTCTTGCTTTGTTGCTCAGGCTGGTCTCAAACTCCTGGTTTCAA GCAGTCTTCCTGCCTTGGCTTCCCAAAGTGCTGGGATTAAAGGTGTGAGCCACTGCACCC AGCCTCTTCTTAGAATTTAATTTTAAATTATGATGAATGTACAACATTCCATTATTCCAG TATAAGCCTCTGTCTGTTTGAATGAGGTTAATGACAGTTCTTCAGGGTTAAAATAAGATT CTGTAGTAGTCATCTCTATAGCTGTACAGAAATAGCACAGACACCTTTTTTTCTACTTTG ATGTTATAAATTTCATCACAGACTAATTTGAGGTATCTTTGCTTTGGCAGGCGTGACAGC AGCTGCTTCACAGTTGTGTTAAATGCCTGTTCATCAGCATCCCACTCTAATGATAAAAAC TGTTATATTGGTTTCTTTGGGGTAGATCCACAGCCAGAATTTCAAATTCACTGCTTTTCT GAAGTAAGTTTGCAAAGA |
Restriction Sites | Please inquire |
ACCN | NM_001013703 |
Insert Size | 5500 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001013703.2, NP_001013725.2 |
RefSeq Size | 5532 bp |
RefSeq ORF | 4950 bp |
Locus ID | 440275 |
UniProt ID | Q9P2K8 |
Protein Families | Druggable Genome, Protein Kinase |
Gene Summary | This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014] |
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