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CACNA2D2 (NM_001005505) Human Untagged Clone
CAT＃: SC300988
CACNA2D2 (untagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 2 (CACNA2D2), transcript variant 1
CNY 7,984.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CACNA2D; CASVDD |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001005505 edited
CATCTTGAATGGAAACATGGCGGTGCCGGCTCGGACCTGCGGCGCCTCTCGGCCCGGCCC AGCGCGGACTGCGCGCCCCTGGCCCGGCTGCGGCCCCCACCCTGGCCCCGGCACCCGGCG CCCGACGTCCGGGCCCCCGCGCCCGCTGTGGCTGCTGCTGCCGCTTCTACCGCTGCTCGC CGCCCCCGGCGCCTCTGCCTACAGCTTCCCCCAGCAGCACACGATGCAGCACTGGGCCCG GCGTCTGGAGCAGGAGGTCGACGGCGTGATGCGGATTTTTGGAGGCGTCCAGCAGCTCCG TGAGATTTACAAGGACAACCGGAACCTGTTCGAGGTACAGGAGAATGAGCCTCAGAAGTT GGTGGAGAAGGTGGCAGGGGACATTGAGAGCCTTCTGGACAGGAAGGTGCAGGCCCTGAA GAGACTGGCTGATGCTGCAGAGAACTTCCAGAAAGCACACCGCTGGCAGGACAACATCAA GGAGGAAGACATCGTGTACTATGACGCCAAGGCTGACGCTGAGCTGGACGACCCTGAGAG TGAGGATGTGGAAAGGGGGTCTAAGGCCAGCACCCTAAGGCTGGACTTCATCGAGGACCC AAACTTCAAGAACAAGGTCAACTATTCATACGCGGCTGTACAGATCCCTACGGACATCTA CAAAGGCTCCACTGTCATCCTCAATGAGCTCAACTGGACAGAGGCCCTGGAGAATGTGTT CATGGAAAACCGCAGACAAGACCCCACACTGCTGTGGCAGGTCTTCGGCAGCGCCACAGG AGTCACTCGCTACTACCCGGCCACCCCGTGGCGAGCCCCCAAGAAGATCGACCTGTACGA TGTCCGAAGGAGACCCTGGTATATCCAGGGGGCCTCGTCACCCAAAGACATGGTCATCAT CGTGGATGTGAGTGGCAGTGTGAGCGGCCTGACCCTGAAGCTGATGAAGACATCTGTCTG CGAGATGCTGGACACGCTGTCTGATGATGACTATGTGAATGTGGCCTCGTTCAACGAGAA GGCACAGCCTGTGTCATGCTTCACACACCTGGTGCAGGCCAATGTGCGCAACAAGAAGGT GTTCAAGGAAGCTGTGCAGGGCATGGTGGCCAAGGGCACCACAGGCTACAAGGCCGGCTT TGAGTATGCCTTTGACCAGCTGCAGAACTCCAACATCACTCGGGCCAACTGCAACAAGAT GATCATGATGTTCACGGATGGTGGTGAGGACCGCGTGCAGGACGTCTTTGAGAAGTACAA TTGGCCAAACCGGACGGTGCGCGTGTTTACTTTCTCCGTGGGGCAGCATAACTATGACGT CACACCGCTGCAGTGGATGGCCTGTGCCAACAAAGGCTACTATTTTGAGATCCCTTCCAT CGGAGCCATCCGCATCAACACACAGGAATATCTAGATGTGTTGGGCAGGCCCATGGTGCT GGCAGGCAAGGAGGCCAAGCAGGTGCAGTGGACCAACGTGTATGAGGATGCACTGGGACT GGGGTTGGTGGTAACAGGGACCCTCCCTGTTTTCAACCTGACACAGGATGGCCCTGGGGA AAAGAAGAACCAGCTGATCCTGGGCGTGATGGGCATTGACGTGGCTCTGAATGACATCAA GAGGCTGACCCCCAACTACACGCTTGGAGCCAACGGCTATGTGTTTGCCATTGACCTGAA CGGCTACGTGTTGCTGCACCCCAATCTCAAGCCCCAGACCACCAACTTCCGGGAGCCTGT GACTCTGGACTTCCTGGATGCGGAGCTAGAGGATGAGAACAAGGAAGAGATCCGTCGGAG CATGATTGATGGCAACAAGGGCCACAAGCAGATCAGAACGTTGGTCAAGTCCCTGGATGA GAGGTACATAGATGAGGTGACACGGAACTACACCTGGGTGCCTATAAGGAGCACTAACTA CAGCCTGGGGCTGGTGCTCCCACCCTACAGCACCTTCTACCTCCAAGCCAATCTCAGTGA CCAGATCCTGCAGGTCAAGTATTTTGAGTTCCTGCTCCCCAGCAGCTTTGAGTCTGAAGG ACACGTTTTCATTGCTCCCAGAGAGTACTGCAAGGACCTGAATGCCTCAGACAACAACAC CGAGTTCCTGAAAAACTTTATTGAGCTCATGGAGAAAGTGACTCCAGACTCCAAGCAGTG CAACAACTTCCTTCTGCACAACCTGATCTTGGACACGGGCATCACGCAGCAGCTGGTAGA GCGTGTGTGGAGGGACCAGGATCTCAACACGTACAGCCTACTGGCCGTGTTCGCTGCCAC AGACGGTGGCATCACCCGAGTCTTCCCCAACAAGGCAGCTGAGGACTGGACAGAGAACCC TGAGCCCTTCAATGCCAGCTTCTACCGCCGCAGCCTGGATAACCACGGTTATGTCTTCAA GCCCCCACACCAGGATGCCCTGTTAAGGCCGCTGGAGCTGGAGAATGACACTGTGGGCAT CCTCGTCAGCACAGCTGTGGAGCTCAGCCTAGGCAGGCGCACACTGAGGCCAGCAGTGGT GGGCGTCAAGCTGGACCTAGAGGCTTGGGCTGAGAAGTTCAAGGTGCTAGCCAGCAACCG TACCCACCAAGACCAGCCTCAGAAGTGCGGCCCCAACAGCCACTGTGAGATGGACTGCGA GGTTAACAATGAGGACTTACTCTGTGTCCTCATTGATGATGGAGGATTCCTGGTGCTGTC AAACCAGAACCATCAGTGGGACCAGGTGGGCAGGTTCTTCAGTGAGGTGGATGCCAACCT GATGCTGGCACTCTACAATAACTCCTTCTACACCCGCAAGGAGTCCTATGACTATCAGGC AGCCTGTGCCCCTCAGCCCCCTGGCAACCTGGGTGCTGCACCCCGGGGTGTCTTTGTGCC CACCGTTGCAGATTTCCTTAACCTGGCCTGGTGGACCTCTGCTGCCGCCTGGTCCCTGTT CCAGCAGCTTCTCTACGGCCTCATCTACCACAGCTGGTTCCAAGCAGACCCCGCGGAGGC CGAGGGGAGCCCCGAGACACGCGAGAGCAGCTGCGTCATGAAACAGACCCAGTACTACTT CGGCTCGGTAAACGCCTCCTACAACGCCATCATCGACTGCGGAAACTGCTCCAGGCTGTT CCACGCGCAGAGACTGACCAACACCAATCTTCTCTTTGTGGTGGCCGAGAAGCCGCTGTG CAGCCAGTGCGAGGCTGGCCGGCTGCTGCAGAAGGAGACGCACTGCCCAGCGGACGGCCC GGAGCAGTGTGAGCTAGTGCAGAGACCGCGATACCGGAGAGGCCCGCACATCTGCTTCGA CTACAACGCGACAGAAGATACCTCAGACTGTGGCCGCGGGGCCTCCTTCCCGCCGTCGCT GGGCGTCCTGGTCTCCCTGCAACTGCTGCTCCTCCTGGGCCTGCCGCCCCGGCCGCAGCC TCAAGTCCTCGTCCACGCCTCTCGCCGCCTCTGAGCACCCTGCCCCACCCCACCTCCACT CCCACCTCACCCGGCCTCTTCGCCTTTCCCACCCTCCTGCCCCACACTCCCCGCCTTAGA GCCTCGTCCCTCCCTCACTGAAGGACCTGAGCTGGCCAGGCCCTGAGAGTCTGGTCTGCG CCTTGGGATGGGGAGTCCCAAAGCGGGACGCCGCAGGTGTTTGGCACCCAAATCACATCT CACCTCCGAACTGTTCAAGTGTCCCCAGACCCTTCTTGCCTGCTGGGCTCCCCCCAGTGG GATGGGACAGGGAGGCCACACGCACTGGTGCCAAAACCAGGCCTCTGCTGCCGCCCTTCC TGGAGGCTGCCTATGTTGGGGGGGACCCTGCCTCAGCTGACCCGGCCTCTCTGCCCCACC CAAGCCCAAACTTGGTTTCTGTGAGAATAGTGGAGGAAGGTGAGATGGCCAGTTTGAAGC CTGTGCCTCCCAGCTTAAATCCTAGCAGGAGAGAGGCTCTGGGGCAGCCCCCATGGGCTC CTGCCCCTTTCAGGCCTACAGCCACATCCCCAAGCCCACCAGGTGTCAGGATAGTCACAG TGATACCAGTTCAGACACTACCCCATATACACCTGGAACATTGAGGATGGAAACTGGACT CACATTCGACATACCCCACTGGGCACACGCACAAACACACACACTATGGGGTGGGGTGGG TGTAGGGGCTTACAAAGCCTTACACAGGGCGAGGGGTTGGTGGGAGGGTTGGCACCTGCA CACTCCATCTCCTGCTCACCACCTGCCTCTAATCTGAGCTGCAGCCTGGCTGGTCCTCCC ATTTCTAAAGCTGAATGTCAAACAGTGCCAAATGCTGGGGCAGGGGGTGAAGAACCCTCT GTCCCACCCCTAGCCACCAGTGTCCTCCAAGTGCCCCCTCACCTCTCCAGGTGCTCATTG TAACCATTTCTCACTAGTGTCAGGCCCCCAGTGGGACCACATGCCACTGCCTGCACCTTT CGGCAGAGGAACCCCCACCAGACATCACCCTTTGCCTTAGCAGGGGTGACTTTGTCTCTC CTGGCTGGGCCATCCTTCCGCCAATCTGGCCCTTACACACTCAGGCCTGTGCCCACTCCC TATCTCCTTCCCACCCCTACACACACACTCCCTGCTTGCAGGAGGCCAAACTGTCCCTCC CTTGCTGAACACACACACACACACACACACACAGGTGGGGACTGGGCACAGCTCTTCACA CCATTCATTCTGGTCATTTCCCCCAAAGGCATCCCAGCCTGGGGGCCAGTGGGGAACTGA GGGCAAGGGGATATAGTGATGGGGCTCAGATGGACTGGGAGGAGGGGGAGGGTGATGCAT TAATTAATGGCTTCGTTAATTAATGTCATGTTGCTTGTCGCTTTCTCAGTGTGTGTGTGT GGTCCATGCCCACTGCTGGTGCCAGGGTGGGTGTCCATGTGCACCCGGCCTGGATGCCAG CTGTGTCCTTCGGGGGCGTGCGTGTAACTGTAGTGTAGTCAGGTGCTCAATGGAGAATAT AAACATATACAGAAAAATATATATTTTAAGTTTAAAAAACAGAAAAACAGACAAAACAAT CCCCATCAGGTAGCTGTCTAACCCCCAGCTGGGTCTAATCCTTCTCATTACCCACCCGAC CTGGCTGCCCCTCACCTTGGGCTGGGGGACTGGGGGGCCATTTCCTTTTCTCTGCCCTTT TTTTGTTGTTCTATTTTGTACAGACAAGTTGGAAAAACAACAGCGACAAAAAAGTCAAGA AACTTTGTAAAATATAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001005505 unedited
TGACAGGTTCGGATTTGTAATACCACTTACTATAGGGCGGCCGCGCATTCGCCCTTCCGC ATCTTGAAGGAAACATGGCGGTGCCGGCTCGGACCTGCGGCGCCTCTCGGCCCGGCCCAG CGCGGACTGCGCGCCCCTGGCCCGGCTGCGGCCCCCACCCTGGCCCCGGCACCCGGCGCC CGACGTCCGGGCCCCCGCGCCCGCTGTGGCTGCTGCTGCCGCTTCTACCGCTGCTCGCCG CCCCCGGCGCCTCTGCCTACAGCTTCCCCCAGCAGCACACGATGCAGCACTGGGCCCGGC GTCTGGAGCAGGAGGTCGACGGCGTGATGCGGATTTTTGGAGGCGTCCAGCAGCTCCGTG AGATTTACAAGGACAACCGGAACCTGTTCGAGGTACAGGAGAATGAGCCTCAGAAGTTGG TGGAGAAGGTGGCAGGGGACATTGAGAGCCTTCTGGACAGGAAGGTGCAGGCCCTGAAGA GACTGGCTGATGCTGCAGAGAACTTCCAGAAAGCACACCGCTGGCAGGACAACATCAAGG AGGAAGACATCGTGTACTATGACGCCAAGGCTGACGCTGAGCTGGACGACCCTGAGAGTG AGGATGTGGAAAGGGGGTCTAAGGCCAGCACCCTAAGGCTGGACTTCATCGAGGACCCAA ACTTCAAGAACAGGTCAACTATTCATACGCGGCTGTACAGATCCCTACCGACATCTACAA AGGCTCCACTGTCATCCTCAATGAGCTCAACTGGACAGAGGCCCTGGAGAATGTGTTCAT GGAAAACCGCAGACAAGACCCCACACTGCTGTGGCAGGTCTTCGGCAGCGCCACAAGAGT CACTCGCTACTACCCGGCCACCCCGTG >OriGene 3' genomic read for NM_001005505 unedited
CTCGGAATGGCACTTCCAGGACCGGAAAAGCACTGGGGAAGGGTCACAGGATGCCACCCG GATCTGTTCAGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTT TTTTTTTTATATTTTACAAAGTTTCTTGACTTTTTTGTCGCTGTTGTTTTTCCAACTTGT CTGTACAAAATACAACAACAAAAAAGGGCAGAGAAAAGGAAATGGCCCCCCAGTCCCCCA GCCCAAGGTGAGGGGCAGCCAGGTCGGGTGGGTAATGAGAAGGATTACACCCAGCTGGGG GTTAAACAGCTACCTGATGGGGATTGTTTTGTCTGTTTTTCTGTTTTTTAAACTTAAAAT ATATATTTTTCTGTATATGTTTATATTCTCCATTGAGCACCTGACTACACTACAGTTACA CGCACGCCCCCGAAGGACACAGCTGGCATCCAGGCCGGGTGCACATGGACACCCACCCTG GCACCAGCAGTGGGCATGGACCACACACACACACTGAGAAAGCGACTAGCAACATGACAT TAATTAACGAAGCCATTAATTAATGCATCACCCTCCCCCTCCTCCCAGTCCATCTGAGCC CCATCACTATATCACCTTGCCCTCAGTTCCCACTGGCCCTCAGGCTGGGATGCCTTTTGG GGAAATGACCAGAATGAATGGTGTGAANAGCTTGCCCAGTCCCCACCTGTGTGTGCGTGT GTGTGCGTGTGTTCACCAAGGGAGGACAGTTTTGGCCTCCTGCAACCAGGGATTGTGTGT TTAGGGGTGGGAAGAAAAAGGGAATGGGCACAGCCCTGGATGTGTAAGGGCCAAAATTGG CGCAAGATTGGCCCAACCAGGAAAAACC |
| Restriction Sites | Please inquire |
| ACCN | NM_001005505 |
| Insert Size | 5300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001005505.1, NP_001005505.1 |
| RefSeq Size | 5343 bp |
| RefSeq ORF | 3438 bp |
| Locus ID | 9254 |
| UniProt ID | Q9NY47 |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Gene Summary | Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014] Transcript Variant: This variant (1) lacks an alternate in-frame exon in the central coding region and uses an alternate in-frame splice site in the 3' coding region compared to variant 3. The encoded isoform (a) is shorter than isoform c. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219452 | CACNA2D2 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 2 (CACNA2D2), transcript variant 1 |
CNY 7,976.00 |
|
| RC219452L3 | Lenti-ORF clone of CACNA2D2 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 2 (CACNA2D2), transcript variant 1 |
CNY 13,300.00 |
|
| RC219452L4 | Lenti-ORF clone of CACNA2D2 (mGFP-tagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 2 (CACNA2D2), transcript variant 1 |
CNY 13,300.00 |
|
| RG219452 | CACNA2D2 (tGFP-tagged) - Human calcium channel, voltage-dependent, alpha 2/delta subunit 2 (CACNA2D2), transcript variant 1 |
CNY 12,540.00 |
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