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Plakophilin 2 (PKP2) (NM_001005242) Human Untagged Clone
CAT＃: SC300868
PKP2 (untagged)-Human plakophilin 2 (PKP2), transcript variant 2a
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARVD9 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC300868 representing NM_001005242.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCAGCCCCCGGCGCCCCAGCTGAGTACGGCTACATCCGGACCGTCCTGGGCCAGCAGATCCTGGGA CAACTGGACAGCTCCAGCCTGGCGCTGCCCTCCGAGGCCAAGCTGAAGCTGGCGGGGAGCAGCGGCCGC GGCGGCCAGACAGTCAAGAGCCTGCGGATCCAGGAGCAGGTGCAGCAGACCCTCGCCCGGAAGGGCCGC AGCTCCGTGGGCAACGGAAATCTTCACCGAACCAGCAGTGTTCCTGAGTATGTCTACAACCTACACTTG GTTGAAAATGATTTTGTTGGAGGCCGTTCCCCTGTTCCTAAAACCTATGACATGCTAAAGGCTGGCACA ACTGCCACTTATGAAGGTCGCTGGGGAAGAGGAACAGCACAGTACAGCTCCCAGAAGTCCGTGGAAGAA AGGTCCTTGAGGCATCCTCTGAGGAGACTGGAGATTTCTCCTGACAGCAGCCCGGAGAGGGCTCACTAC ACGCACAGCGATTACCAGTACAGCCAGAGAAGCCAGGCTGGGCACACCCTGCACCACCAAGAAAGCAGG CGGGCCGCCCTCCTAGTGCCACCGAGATATGCTCGTTCCGAGATCGTGGGGGTCAGCCGTGCTGGCACC ACAAGCAGGCAGCGCCACTTTGACACATACCACAGACAGTACCAGCATGGCTCTGTTAGCGACACCGTT TTTGACAGCATCCCTGCCAACCCGGCCCTGCTCACGTACCCCAGGCCAGGGACCAGCCGCAGCATGGGC AACCTCTTGGAGAAGGAGAACTACCTGACGGCAGGGCTCACTGTCGGGCAGGTCAGGCCGCTGGTGCCC CTGCAGCCCGTCACTCAGAACAGGGCTTCCAGGTCCTCCTGGCATCAGAGCTCCTTCCACAGCACCCGC ACGCTGAGGGAAGCTGGGCCCAGTGTCGCCGTGGATTCCAGCGGGAGGAGAGCGCACTTGACTGTCGGC CAGGCGGCCGCAGGGGGAAGTGGGAATCTGCTCACTGAGAGAAGCACTTTCACTGACTCCCAGCTGGGG AATGCAGACATGGAGATGACTCTGGAGCGAGCAGTGAGTATGCTCGAGGCAGACCACATGCTGCCATCC AGGATTTCTGCTGCAGCTACTTTCATACAGCACGAGTGCTTCCAGAAATCTGAAGCTCGGAAGAGGGTT AACCAGCTTCGTGGCATCCTCAAGCTTCTGCAGCTCCTAAAAGTTCAGAATGAAGACGTTCAGCGAGCT GTGTGTGGGGCCTTGAGAAACTTAGTATTTGAAGACAATGACAACAAATTGGAGGTGGCTGAACTAAAT GGGGTACCTCGGCTGCTCCAGGTGCTGAAGCAAACCAGAGACTTGGAGACTAAAAAACAAATAACAGGT TTGCTGTGGAATTTGTCATCTAATGACAAACTCAAGAATCTCATGATAACAGAAGCATTGCTTACGCTG ACGGAGAATATCATCATCCCCTTTTCTGGGTGGCCTGAAGGAGACTACCCAAAAGCAAATGGTTTGCTC GATTTTGACATATTCTACAACGTCACTGGATGCCTAAGAAACATGAGTTCTGCTGGCGCTGATGGGAGA AAAGCGATGAGAAGATGTGACGGACTCATTGACTCACTGGTCCATTATGTCAGAGGAACCATTGCAGAT TACCAGCCAGATGACAAGGCCACGGAGAATTGTGTGTGCATTCTTCATAACCTCTCCTACCAGCTGGAG GCAGAGCTCCCAGAGAAATATTCCCAGAATATCTATATTCAAAACCGGAATATCCAGACTGACAACAAC AAAAGTATTGGATGTTTTGGCAGTCGAAGCAGGAAAGTAAAAGAGCAATACCAGGACGTGCCGATGCCG GAGGAAAAGAGCAACCCCAAGGGCGTGGAGTGGCTGTGGCATTCCATTGTTATAAGGATGTATCTGTCC TTGATCGCCAAAAGTGTCCGCAACTACACACAAGAAGCATCCTTAGGAGCTCTGCAGAACCTCACGGCC GGAAGTGGACCAATGCCGACATCAGTGGCTCAGACAGTTGTCCAGAAGGAAAGTGGCCTGCAGCACACC CGAAAGATGCTGCATGTTGGTGACCCAAGTGTGAAAAAGACAGCCATCTCGCTGCTGAGGAATCTGTCC CGGAATCTTTCTCTGCAGAATGAAATTGCCAAAGAAACTCTCCCTGATTTGGTTTCCATCATTCCTGAC ACAGTCCCGAGTACTGACCTTCTCATTGAAACTACAGCCTCTGCCTGTTACACATTGAACAACATAATC CAAAACAGTTACCAGAATGCACGCGACCTTCTAAACACCGGGGGCATCCAGAAAATTATGGCCATTAGT GCAGGCGATGCCTATGCCTCCAACAAAGCAAGTAAAGCTGCTTCCGTCCTTCTGTATTCTCTGTGGGCA CACACGGAACTGCATCATGCCTACAAGAAGGCTCAGTTTAAGAAGACAGATTTTGTCAACAGCCGGACT GCCAAAGCCTACCACTCCCTTAAAGACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001005242 |
| Insert Size | 2514 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001005242.2 |
| RefSeq Size | 4307 bp |
| RefSeq ORF | 2514 bp |
| Locus ID | 5318 |
| UniProt ID | Q99959 |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
| MW | 92.8 kDa |
| Gene Summary | This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008] Transcript Variant: This transcript variant (2a) lacks an alternate exon as compared to transcript variant 2b and encodes the shorter isoform (2a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210514 | PKP2 (Myc-DDK-tagged)-Human plakophilin 2 (PKP2), transcript variant 2a |
CNY 6,128.00 |
|
| RC210514L1 | Lenti ORF clone of Human plakophilin 2 (PKP2), transcript variant 2a, Myc-DDK-tagged |
CNY 8,528.00 |
|
| RC210514L2 | Lenti ORF clone of Human plakophilin 2 (PKP2), transcript variant 2a, mGFP tagged |
CNY 9,030.00 |
|
| RC210514L3 | Lenti ORF clone of Human plakophilin 2 (PKP2), transcript variant 2a, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC210514L4 | Lenti ORF clone of Human plakophilin 2 (PKP2), transcript variant 2a, mGFP tagged |
CNY 9,030.00 |
|
| RG210514 | PKP2 (tGFP-tagged) - Human plakophilin 2 (PKP2), transcript variant 2a |
CNY 7,728.00 |
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