GDF6 (NM_001001557) Human Untagged Clone
CAT#: SC300216
GDF6 (untagged)-Human growth differentiation factor 6 (GDF6)
CNY 5,488.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | BMP-13; BMP13; CDMP2; KFM; KFS; KFS1; KFSL; SGM1; SYNS4 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_001001557 edited
ATGGATACTCCCAGGGTCCTGCTCTCGGCCGTCTTCCTCATCAGTTTTCTGTGGGATTTG CCCGGTTTCCAGCAGGCTTCCATCTCATCCTCCTCGTCGTCCGCCGAGCTGGGTTCCACC AAGGGCATGCGAAGCCGCAAGGAAGGCAAGATGCAGCGGGCGCCGCGCGACAGTGACGCG GGCCGGGAGGGCCAGGAACCACAGCCGCGGCCTCAGGACGAACCCCGGGCTCAGCAGCCC CGGGCGCAGGAGCCGCCAGGCAGGGGTCCGCGCGTGGTGCCCCACGAGTACATGCTGTCA ATCTACAGGACTTACTCCATCGCTGAGAAGCTGGGCATCAATGCCAGCTTTTTCCAGTCT TCCAAGTCGGCTAATACGATCACCAGCTTTGTAGACAGGGGACTAGACGATCTCTCGCAC ACTCCTCTCCGGAGACAGAAGTATTTGTTTGATGTGTCCATGCTCTCAGACAAAGAAGAG CTGGTGGGCGCGGAGCTGCGGCTCTTTCGCCAGGCGCCCTCAGCGCCCTGGGGGCCACCA GCCGGGCCGCTCCACGTGCAGCTCTTCCCTTGCCTTTCGCCCCTACTGCTGGACGCGCGG ACCCTGGACCCGCAGGGGGCGCCGCCGGCCGGCTGGGAAGTCTTCGACGTGTGGCAGGGC CTGCGCCACCAGCCCTGGAAGCAGCTGTGCTTGGAGCTGCGGGCCGCATGGGGCGAGCTG GACGCCGGGGAGGCCGAGGCGCGCGCGCGGGGACCCCAGCAACCGCCGCCCCCGGACCTG CGGAGTCTGGGCTTCGGCCGGAGGGTGCGGCCTCCCCAGGAGCGGGCCCTGCTGGTGGTA TTCACCAGATCCCAGCGCAAGAACCTGTTCGCAGAGATGCGCGAGCAGCTGGGCTCGGCC GAGGCTGCGGGCCCGGGCGCGGGCGCCGAGGGGTCGTGGCCGCCGCCGTCGGGCGCCCCG GATGCCAGGCCTTGGCTGCCCTCGCCCGGCCGCCGGCGGCGGCGCACGGCCTTCGCCAGT CGCCATGGCAAGCGGCACGGCAAGAAGTCCAGGCTACGCTGCAGCAAGAAGCCCCTGCAC GTGAACTTCAAGGAGCTGGGCTGGGACGACTGGATTATCGCGCCCCTGGAGTACGAGGCC TATCACTGCGAGGGTGTATGCGACTTCCCGCTGCGCTCGCACCTGGAGCCCACCAACCAC GCCATCATCCAGACGCTGATGAACTCCATGGACCCCGGCTCCACCCCGCCCAGCTGCTGC GTGCCCACCAAATTGACTCCCATCAGCATTCTATACATCGACGCGGGCAATAATGTGGTC TACAAGCAGTACGAGGACATGGTGGTGGAGTCGTGCGGCTGCAGGTAGCGGTGCCTTTCC CGCCGCCTTGGCCCGGAACCAAGGTGGGCCAAGGTCCGCCTTGCAGGGGAGGCCTGGCTG CAGAGAGGCGGAGGAGGAAGCT >OriGene 5' read for NM_001001557 unedited
GGGCGATTGTATACGACTCCTATAGGGCGGCGCGGGAATTCGCCCTTATGGATACTCCCA GGGTCCTGCTCTCGGCCGTCTTCCTCATCAGTTTTCTGTGGGATTTGCCCGGTTTCCAGC AGGCTTCCATCTCATCCTCCTCGTCGTCCGCCGAGCTGGGTTCCACCAAGGGCATGCGAA GCCGCAAGGAAGGCAAGATGCAGCGGGCGCCGCGCGACAGTGACGCGGGCCGGGAGGGCC AGGAACCACAGCCGCGGCCTCAGGACGAACCCCGGGCTCAGCAGCCCCGGGCGCAGGAGC CGCCAGGCAGGGGTCCGCGCGTGGTGCCCCACGAGTACATGCTGTCAATCTACAGGACTT ACTCCATCGCTGAGAAGCTGGGCATCAATGCCAGCTTTTTCCAGTCTTCCAAGTCGGCTA ATACGATCACCAGCTTTGTAGACAGGGGACTAGACGATCTCTCGCACACTCCTCTCCGGA GACAGAAGTATTTGTTTGATGTGTCCATGCTCTCAGACAAAGAAGAGCTGGTGGGCGCGG AGCTGCGGCTCTTTCGCCAGGCGCCCTCAGCGCCCTGGGGGCCACCAGCCGGGCCGCTCC ACGTGCAGCTCTTCCCTTGCCTTTCGCCCCTACTGCTGGACGCGCGGACCCTGGACCCGC AGGGGGCGCCGCCGGCCGGCTGGGAAGTCTTCGACGTGTGGCAGGGCCTGCGCCACCAGC CCTGGAAGCAGCTGTGCTTGGAGCTGCGGGCCGCATGGGGCGAGCTGGACGCCGGGGAGG CCGAGGCGCGCGCGCGGGGACCCCAGCAACCGCCGCCCCCGGACCTGCGGAGTCTGGGCT TCGGCCGGAGGGTGCGGCCTCCCCAGGAGCGGGCCCTGCTGGTGGTATTCACCAGATCCC AGCGCAAGACCTTGTTCGCAGAGAATGCCGCGAAGCAAGGCTG |
Restriction Sites | Please inquire |
ACCN | NM_001001557 |
Insert Size | 1500 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001001557.1, NP_001001557.1 |
RefSeq Size | 3716 bp |
RefSeq ORF | 1368 bp |
Locus ID | 392255 |
UniProt ID | Q6KF10 |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | TGF-beta signaling pathway |
Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC211366 | GDF6 (Myc-DDK-tagged)-Human growth differentiation factor 6 (GDF6) |
CNY 5,488.00 |
|
RC211366L1 | Lenti ORF clone of Human growth differentiation factor 6 (GDF6), Myc-DDK-tagged |
CNY 7,888.00 |
|
RC211366L2 | Lenti ORF clone of Human growth differentiation factor 6 (GDF6), mGFP tagged |
CNY 5,890.00 |
|
RC211366L3 | Lenti ORF clone of Human growth differentiation factor 6 (GDF6), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC211366L4 | Lenti ORF clone of Human growth differentiation factor 6 (GDF6), mGFP tagged |
CNY 5,890.00 |
|
RG211366 | GDF6 (tGFP-tagged) - Human growth differentiation factor 6 (GDF6) |
CNY 7,088.00 |