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KDM4C (NM_015061) Human Untagged Clone
CAT＃: SC128199
KDM4C (untagged)-Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1
CNY 7,360.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GASC1; JHDM3C; JMJD2C; TDRD14C |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_015061 edited
CCTCGACGGGAGGGTGAGGCGCGGCGCAGTGATCGGGCGGCCGGGGTCCTGTGCGCGTGC GCAGCGAACAGCTGTCACCTAGTGCGGAACAAGTCTCCCAAATTTCCCAAATCTCCCTGG GCCGGAGGCCACTGTCTTCTCTTCCTCCTCCACCGAGTCGTGCTCTCGCCCCAACCCGCG CGCCAGACACTGCCCTAACCATCATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCA GCTGTAAGATAATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAACAAATACC TTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTA AGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTCATTCCAGCACCAA TTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAG CGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGAT ACTTGGATTACGAAGATTTGGAGCGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTA TCTATGGTGCAGATATTAATGGGAGCATATATGATGAGGGTGTGGATGAATGGAACATAG CTCGCCTCAATACAGTCTTGGATGTGGTTGAAGAAGAGTGTGGCATTTCTATTGAGGGTG TAAATACCCCATATCTCTATTTTGGCATGTGGAAGACCACGTTTGCATGGCACACCGAAG ACATGGACCTCTATAGCATTAATTATCTCCACTTTGGAGAGCCCAAGTCTTGGTATGCTA TACCTCCGGAGCATGGAAAACGACTTGAAAGACTAGCTCAAGGTTTTTTCCCAAGCAGCT CCCAAGGGTGTGATGCATTTCTTCGCCACAAGATGACATTGATTTCTCCATCAGTATTGA AGAAATATGGTATTCCCTTTGACAAGATAACCCAGGAGGCTGGAGAATTCATGATCACTT TCCCATATGGCTACCATGCTGGTTTTAATCATGGTTTCAACTGTGCAGAATCTACAAATT TTGCTACTGTCAGATGGATTGACTATGGAAAAGTTGCCAAATTGTGCACTTGCAGGAAAG ACATGGTGAAGATTTCAATGGATATCTTTGTGAGGAAATTTCAGCCAGACAGATATCAGC TTTGGAAACAAGGAAAGGATATATACACCATTGATCACACGAAGCCTACTCCAGCATCCA CCCCTGAAGTAAAAGCATGGCTGCAGAGGAGGAGGAAAGTAAGAAAAGCATCCCGAAGCT TCCAGTGTGCTAGGTCTACCTCTAAAAGGCCTAAGGCTGATGAGGAAGAGGAAGTGTCAG ATGAAGTCGATGGGGCAGAGGTCCCTAACCCCGACTCAGTCACAGATGACCTCAAGGTCA GTGAAAAGTCAGAAGCAGCAGTGAAGCTGAGGAACACAGAAGCATCTTCAGAAGAAGAGT CATCTGCTAGCAGGATGCAGGTGGAGCAGAATTTATCAGATCATATCAAACTCTCAGGAA ACAGCTGCTTAAGTACATCTGTAACAGAAGACATAAAAACTGAGGATGACAAAGCTTATG CATATAGAAGTGTACCTTCTATATCCAGTGAGGCTGATGATTCCATTCCATTGTCTAGTG GCTATGAGAAGCCCGAGAAATCAGACCCATCCGAGCTTTCATGGCCAAAGTCACCTGAGT CATGCTCATCAGTGGCAGAGAGTAATGGTGTGTTAACAGAGGGAGAAGAGAGTGATGTGG AGAGCCATGGGAATGGCCTTGAACCTGGGGAAATCCCAGCGGTCCCCAGTGGAGAGAGAA ATAGCTTCAAAGTCCCCAGTATAGCAGAGGGAGAGAACAAAACCTCTAAGAGTTGGCGCC ATCCACTTAGCAGGCCTCCAGCAAGATCTCCGATGACTCTTGTGAAGCAGCAGGCGCCAA GTGATGAAGAATTGCCTGAGGTTCTGTCCATTGAGGAGGAAGTGGAAGAAACAGAGTCTT GGGCGAAACCTCTCATCCACCTTTGGCAGACGAAGTCCCCTAACTTCGCAGCTGAGCAAG AGTATAATGCAACAGTGGCCAGGATGAAGCCACACTGTGCCATCTGCACTCTGCTCATGC CGTACCACAAGCCAGATAGCAGCAATGAAGAAAATGATGCTAGATGGGAGACAAAATTAG ATGAAGTCGTTACATCGGAGGGAAAGACTAAGCCCCTCATACCAGAGATGTGTTTTATTT ATAGTGAAGAAAATATAGAATATTCTCCACCCAATGCCTTCCTTGAAGAGGATGGAACAA GTCTCCTTATTTCCTGTGCAAAGTGCTGCGTACGGGTTCATGCAAGTTGTTATGGTATTC CTTCTCATGAGATCTGTGATGGATGGCTGTGTGCCCGGTGCAAAAGAAATGCGTGGACAG CAGAATGCTGTCTCTGCAATTTGAGAGGAGGTGCTCTTAAGCAAACGAAGAACAATAAGT GGGCCCATGTCATGTGCGCCGTTGCGGTCCCAGAAGTTCGATTCACTAATGTCCCAGAAA GGACACAAATAGATGTAGGCAGAATACCTTTACAGAGGTTAAAATTGAAATGCATCTTCT GCAGACACCGGGTTAAGAGGGTCTCTGGAGCCTGCATCCAGTGTTCCTACGGTCGCTGCC CGGCCTCCTTCCATGTCACTTGTGCCCATGCTGCTGGGGTACTGATGGAGCCTGATGATT GGCCTTATGTGGTGAACATTACATGCTTTCGACATAAGGTCAACCCCAACGTGAAGTCCA AGGCTTGCGAGAAGGTCATTTCCGTGGGTCAAACGGTCATCACGAAGCATCGGAACACCC GGTATTACAGTTGCAGAGTGATGGCTGTGACATCGCAGACCTTCTATGAGGTCATGTTTG ATGATGGCTCCTTTAGCAGAGACACATTTCCTGAGGATATCGTGAGCCGAGACTGTCTGA AGCTGGGCCCACCTGCTGAGGGAGAAGTCGTCCAAGTCAAGTGGCCCGATGGCAAACTCT ATGGAGCAAAATATTTTGGATCAAATATTGCCCACATGTACCAGGTTGAGTTTGAAGATG GATCCCAGATAGCAATGAAGAGAGAGGACATCTACACTTTAGATGAAGAGTTACCCAAGA GAGTGAAAGCTCGATTTTCCACAGCCTCTGACATGCGATTTGAAGACACGTTTTATGGAG CAGACATTATCCAAGGGGAGAGAAAGAGACAAAGAGTGCTGAGCTCCAGGTTTAAGAATG AATATGTGGCCGACCCTATATACCGCACTTTTTTGAAGAGCTCTTTCCAGAAGAAGTGCC AGAAGAGACAGTAGTCTGCATACATCGCTGCAGGCCACAGAGCAGCTTGGGTTGGAAAAG AGAAGATGAAGGGACATCCTTGGGGCTGTGCCGTGAGATTTGCTGGCATAGGTGACAGGG TGTGTCTCTGACAGTGGTAAATCGGGTTTCCAGAGTTTGGTCACCAAAAATACAAAATAC ACMCAATGAATTGGACGCAGCAATCTGAAATCATCTCTAGTCTTGCTTTCACTTGTGAGC AGTTGTCTTCTATGATCCCAAAGAAGTTTTCTAAGTGAAAGGAAATACTAGTGAATCACC CACAAGGAAAAGCCACTGCCACAGAGGAGGCGGGTCCCCTTGTGCGGCTTAGGGCCCTGT CAGGAAACACACGGGGACCTCTCTCTCTAGCTCCAGCAGGTGGCACCTCGGTACCCAGCG GGTAGGGCGATAATTTATATATTTTCCACAGTCAGGGAAGGACTCTCACTTATTTGTTTC AAATTGCAGTTTTTATAAAACATTTTTAAAACACAAATGGCATGTATGCTAATGAGATTT ACCCGTGTGCTATCTGTATTTCCCTTGTACAGAACTTTTACATTTTTGAATATTCCTATT ACTTTTGATTGTGTCTGATGGGAACTGAGTTGTTGGCCTTTGTGAAATGAAATTTTTGGC TCTTGAGAAAGAATTCTTATGAATTGTTATGCGAATTTTATATATTTAAAGAGGGAGATC TGGGGCTGTTATTTTTAAACACTTTTTTTCATAATACATATTCCGAGTAGATATTTATAA AATATATGTTTCTTTCATTATGTGTTTGTAAAATTAGAGTTTAAATAAATATGCTTTGAT GCATAGTTTTGAACTAATGTAACATGATTTTTCTTTTTTAAAACAGCCTGAAAATGTACT AGTGTTTAAAAATAAAGATTTCCATTTTCTCCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_015061 |
| Insert Size | 4300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_015061.2, NP_055876.2 |
| RefSeq Size | 4674 bp |
| RefSeq ORF | 3171 bp |
| Locus ID | 23081 |
| UniProt ID | Q9H3R0 |
| Domains | PHD, TUDOR, JmjC, JmjN |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Kdm4b Histone Demethylase Is a DNA Damage Response Protein and Confers a Survival Advantage following {gamma}-Irradiation
,Leah C. Young, Darin W. McDonald, and Michael J. Hendzel,
J. Biol. Chem., Jul 2013; 288: 21376 - 21388.
,PubMed ID 23744078
[Kdm4c]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211182 | KDM4C (Myc-DDK-tagged)-Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1 |
CNY 7,352.00 |
|
| RC211182L1 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, Myc-DDK-tagged |
CNY 9,752.00 |
|
| RC211182L2 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, mGFP tagged |
CNY 9,752.00 |
|
| RC211182L3 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, Myc-DDK-tagged |
CNY 9,752.00 |
|
| RC211182L4 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, mGFP tagged |
CNY 9,752.00 |
|
| RG211182 | KDM4C (tGFP-tagged) - Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1 |
CNY 8,952.00 |
