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KDM4C (NM_015061) Human Tagged ORF Clone
CAT＃: RC211182
KDM4C (Myc-DDK-tagged)-Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1
ORF Plasmid: tGFP
"NM_015061" in other vectors (6)
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CNY 7,352.00
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | GASC1; JHDM3C; JMJD2C; TDRD14C |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC211182 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTCCATGG AGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGC AAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTCATTCCA GCACCAATTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAGCGA TGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGA AGATTTGGAGCGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATTAATGGG AGCATATATGATGAGGGTGTGGATGAATGGAACATAGCTCGCCTCAATACAGTCTTGGATGTGGTTGAAG AAGAGTGTGGCATTTCTATTGAGGGTGTAAATACCCCATATCTCTATTTTGGCATGTGGAAGACCACGTT TGCATGGCACACCGAAGACATGGACCTCTATAGCATTAATTATCTCCACTTTGGAGAGCCCAAGTCTTGG TATGCTATACCTCCGGAGCATGGAAAACGACTTGAAAGACTAGCTCAAGGTTTTTTCCCAAGCAGCTCCC AAGGGTGTGATGCATTTCTTCGCCACAAGATGACATTGATTTCTCCATCAGTATTGAAGAAATATGGTAT TCCCTTTGACAAGATAACCCAGGAGGCTGGAGAATTCATGATCACTTTCCCATATGGCTACCATGCTGGT TTTAATCATGGTTTCAACTGTGCAGAATCTACAAATTTTGCTACTGTCAGATGGATTGACTATGGAAAAG TTGCCAAATTGTGCACTTGCAGGAAAGACATGGTGAAGATTTCAATGGATATCTTTGTGAGGAAATTTCA GCCAGACAGATATCAGCTTTGGAAACAAGGAAAGGATATATACACCATTGATCACACGAAGCCTACTCCA GCATCCACCCCTGAAGTAAAAGCATGGCTGCAGAGGAGGAGGAAAGTAAGAAAAGCATCCCGAAGCTTCC AGTGTGCTAGGTCTACCTCTAAAAGGCCTAAGGCTGATGAGGAAGAGGAAGTGTCAGATGAAGTCGATGG GGCAGAGGTCCCTAACCCCGACTCAGTCACAGATGACCTCAAGGTCAGTGAAAAGTCAGAAGCAGCAGTG AAGCTGAGGAACACAGAAGCATCTTCAGAAGAAGAGTCATCTGCTAGCAGGATGCAGGTGGAGCAGAATT TATCAGATCATATCAAACTCTCAGGAAACAGCTGCTTAAGTACATCTGTAACAGAAGACATAAAAACTGA GGATGACAAAGCTTATGCATATAGAAGTGTACCTTCTATATCCAGTGAGGCTGATGATTCCATTCCATTG TCTAGTGGCTATGAGAAGCCCGAGAAATCAGACCCATCCGAGCTTTCATGGCCAAAGTCACCTGAGTCAT GCTCATCAGTGGCAGAGAGTAATGGTGTGTTAACAGAGGGAGAAGAGAGTGATGTGGAGAGCCATGGGAA TGGCCTTGAACCTGGGGAAATCCCAGCGGTCCCCAGTGGAGAGAGAAATAGCTTCAAAGTCCCCAGTATA GCAGAGGGAGAGAACAAAACCTCTAAGAGTTGGCGCCATCCACTTAGCAGGCCTCCAGCAAGATCTCCGA TGACTCTTGTGAAGCAGCAGGCGCCAAGTGATGAAGAATTGCCTGAGGTTCTGTCCATTGAGGAGGAAGT GGAAGAAACAGAGTCTTGGGCGAAACCTCTCATCCACCTTTGGCAGACGAAGTCCCCTAACTTCGCAGCT GAGCAAGAGTATAATGCAACAGTGGCCAGGATGAAGCCACACTGTGCCATCTGCACTCTGCTCATGCCGT ACCACAAGCCAGATAGCAGCAATGAAGAAAATGATGCTAGATGGGAGACAAAATTAGATGAAGTCGTTAC ATCGGAGGGAAAGACTAAGCCCCTCATACCAGAGATGTGTTTTATTTATAGTGAAGAAAATATAGAATAT TCTCCACCCAATGCCTTCCTTGAAGAGGATGGAACAAGTCTCCTTATTTCCTGTGCAAAGTGCTGCGTAC GGGTTCATGCAAGTTGTTATGGTATTCCTTCTCATGAGATCTGTGATGGATGGCTGTGTGCCCGGTGCAA AAGAAATGCGTGGACAGCAGAATGCTGTCTCTGCAATTTGAGAGGAGGTGCTCTTAAGCAAACGAAGAAC AATAAGTGGGCCCATGTCATGTGCGCCGTTGCGGTCCCAGAAGTTCGATTCACTAATGTCCCAGAAAGGA CACAAATAGATGTAGGCAGAATACCTTTACAGAGGTTAAAATTGAAATGCATCTTCTGCAGACACCGGGT TAAGAGGGTCTCTGGAGCCTGCATCCAGTGTTCCTACGGTCGCTGCCCGGCCTCCTTCCATGTCACTTGT GCCCATGCTGCTGGGGTACTGATGGAGCCTGATGATTGGCCTTATGTGGTGAACATTACATGCTTTCGAC ATAAGGTCAACCCCAACGTGAAGTCCAAGGCTTGCGAGAAGGTCATTTCCGTGGGTCAAACGGTCATCAC GAAGCATCGGAACACCCGGTATTACAGTTGCAGAGTGATGGCTGTGACATCGCAGACCTTCTATGAGGTC ATGTTTGATGATGGCTCCTTTAGCAGAGACACATTTCCTGAGGATATCGTGAGCCGAGACTGTCTGAAGC TGGGCCCACCTGCTGAGGGAGAAGTCGTCCAAGTCAAGTGGCCCGATGGCAAACTCTATGGAGCAAAATA TTTTGGATCAAATATTGCCCACATGTACCAGGTTGAGTTTGAAGATGGATCCCAGATAGCAATGAAGAGA GAGGACATCTACACTTTAGATGAAGAGTTACCCAAGAGAGTGAAAGCTCGATTTTCCACAGCCTCTGACA TGCGATTTGAAGACACGTTTTATGGAGCAGACATTATCCAAGGGGAGAGAAAGAGACAAAGAGTGCTGAG CTCCAGGTTTAAGAATGAATATGTGGCCGACCCTATATACCGCACTTTTTTGAAGAGCTCTTTCCAGAAG AAGTGCCAGAAGAGACAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC211182 protein sequence
Red=Cloning site Green=Tags(s) MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIP APIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFVAPIYGADING SIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSW YAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAG FNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTP ASTPEVKAWLQRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAV KLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSVTEDIKTEDDKAYAYRSVPSISSEADDSIPL SSGYEKPEKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGNGLEPGEIPAVPSGERNSFKVPSI AEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESWAKPLIHLWQTKSPNFAA EQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEY SPPNAFLEEDGTSLLISCAKCCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKN NKWAHVMCAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTC AHAAGVLMEPDDWPYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEV MFDDGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDGSQIAMKR EDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKRQRVLSSRFKNEYVADPIYRTFLKSSFQK KCQKRQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_015061 |
| ORF Size | 3168 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_015061.6 |
| RefSeq Size | 4687 bp |
| RefSeq ORF | 3171 bp |
| Locus ID | 23081 |
| UniProt ID | Q9H3R0 |
| Domains | PHD, TUDOR, JmjC, JmjN |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 120 kDa |
| Gene Summary | This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211182L1 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, Myc-DDK-tagged |
CNY 9,752.00 |
|
| RC211182L2 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, mGFP tagged |
CNY 9,752.00 |
|
| RC211182L3 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, Myc-DDK-tagged |
CNY 9,752.00 |
|
| RC211182L4 | Lenti ORF clone of Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, mGFP tagged |
CNY 9,752.00 |
|
| RG211182 | KDM4C (tGFP-tagged) - Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1 |
CNY 8,952.00 |
|
| SC128199 | KDM4C (untagged)-Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1 |
CNY 7,360.00 |
