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CLK2 (NM_003993) Human Untagged Clone
CAT＃: SC128171
CLK2 (untagged)-Human CDC-like kinase 2 (CLK2)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003993 edited
AGCATTTCGTCGCCGCGGGGGTGCCGGGACTCCGGCCGCAGTGTCGCCGCCATCACGGAC TTCCTGTGGGACAAGCGCACGGGCCTCGCCGCCAGAACGATGCCGCATCCTCGAAGGTAC CACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCAT AAGCGACGAAGAAGTCGCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGA GAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTTCGTCCGACCGGAGG GTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGA GATGCCTACTATGACACAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGT TACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGAGGCGCAGCCGGACA TTTAGCCGCTCATCTTCGCAGCACAGCAGCCGGAGAGCCAAGAGTGTAGAGGACGACGCT GAGGGCCACCTCATCTACCACGTCGGGGACTGGCTACAAGAGCGATATGAAATCGTTAGC ACCTTAGGAGAGGGGACCTTCGGCCGAGTTGTACAATGTGTTGACCATCGCAGGGGTGGG GCTCGAGTTGCCCTGAAGATCATTAAGAATGTGGAGAAGTACAAGGAAGCAGCTCGACTT GAGATCAACGTGCTAGAGAAAATCAATGAGAAAGACCCTGACAACAAGAACCTCTGTGTC CAGATGTTTGACTGGTTTGACTACCATGGCCACATGTGTATCTCCTTTGAGCTTCTGGGC CTTAGCACCTTCGATTTCCTCAAAGACAACAACTACCTGCCCTACCCCATCCACCAAGTG CGCCACATGGCCTTCCAGCTGTGCCAGGCTGTCAAGTTCCTCCATGATAACAAGCTGACA CATACAGACCTCAAGCCTGAAAATATTCTGTTTGTGAATTCAGACTATGAGCTCACCTAC AACCTAGAGAAGAAGCGAGATGAGCGCAGTGTGAAGAGCACAGCTGTGCGGGTGGTAGAC TTTGGCAGTGCCACCTTTGACCATGAGCACCATAGCACCATTGTCTCCACTCGCCATTAC CGAGCACCAGAAGTCATCCTTGAGTTGGGCTGGTCACAGCCTTGTGATGTGTGGAGTATA GGCTGCATCATCTTTGAATACTATGTGGGATTCACCCTCTTCCAGACCCATGACAACAGA GAGCATCTAGCCATGATGGAAAGGATCTTGGGTCCTATCCCTTCCCGGATGATCCGAAAG ACAAGAAAGCAGAAATATTTTTACCGGGGTCGCCTGGATTGGGATGAGAACACATCAGCT GGGCGCTATGTTCGTGAGAACTGCAAACCGCTGCGGCGGTATCTGACCTCAGAGGCAGAG GAACACCACCAGCTCTTCGATCTGATTGAAAGCATGCTAGAGTATGAACCAGCTAAGCGG CTGACCTTGGGTGAAGCCCTTCAGCATCCTTTCTTCGCCCGCCTTCGGGCTGAGCCGCCC AACAAGTTGTGGGACTCCAGTCGGGATATCAGTCGGTGACGATCAGGCCCTGGGCCCCCC TGCATCTTTTATAGCAGTGGGTGTCCAGTCCAGGACACTGGTGCTTTTTTATACAAGAGA ACGAGCCAGAGTTCACTCC >OriGene 5' read for NM_003993 unedited
ATACGACTCACTATAGGCGGCCGCGAATTCGGCACGAGGGCGGAGCGGAGAGGCCAGAGC CGGAGACCGAGCTGGGATCGGGCCCCGGGCGGGGGCGGTGCGAGCGGCGCCAAGCAGATC TTAGGGGCGGGGACGGAGCCGGGGCGGGCGGGACTGAAGCGGAGCCCGGGAACGGGGCGG GAGGTCCCAGGGTCCCGGGTTGGGGGGGGTGGAGCAGCATTTCGTCGCCGCGGGGGTGCC GGGACTCCGGCCGCAGTGTCGCCGCCATCACGGACTTCCTGTGGGACAAGCGCACGGGCC TCGCCGCCAGAACGATGCCGCATCCTCGAAGGTACCACTCCTCAGAGCGAGGCANGCCGG GGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTCGCTCCTGG TCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCT GNAAGCAGTTATGATTGATCGTTCGTCCGCCGGGGAGGGTGTATGACCGGCGATACTGTG GCAGNCTACAGACGCACGATATAGCCGGGGATCGGGGAGATGCCTACTATGACACAGACT ATCGGCATTCCTATGAATTTCAGGGGGGGAACAGGAAGTTCCGGAACCAGGGCAAAACCG GGGGGGACCCCAAAGGGGGAGGGGGGCACCCGGAATTTTACCTTTTTTTTTCCACCAAAA CCGGGGACCAAGGTTTAAAGGGCACCTTTGGGCCCCTTTTTCCCCGGGGGGGGCGGTTTC CAGAGGATTTAAAACTGCCCCTTTTGGAAGGGGGTCTTCCCGGTGTTCAATGGTGGCCCC CGGGGGGGGGGGGGGCNNCCCCCCAAAAAAAAAAAGGGGGGAAAACACACGCACCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003993 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003993.2, NP_003984.2 |
| RefSeq Size | 2175 bp |
| RefSeq ORF | 1497 bp |
| Locus ID | 1196 |
| UniProt ID | P49760 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208778 | CLK2 (Myc-DDK-tagged)-Human CDC-like kinase 2 (CLK2) |
CNY 3,656.00 |
|
| RC208778L1 | Lenti ORF clone of Human CDC-like kinase 2 (CLK2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC208778L2 | Lenti ORF clone of Human CDC-like kinase 2 (CLK2), mGFP tagged |
CNY 5,890.00 |
|
| RC208778L3 | Lenti ORF clone of Human CDC-like kinase 2 (CLK2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC208778L4 | Lenti ORF clone of Human CDC-like kinase 2 (CLK2), mGFP tagged |
CNY 6,056.00 |
|
| RG208778 | CLK2 (tGFP-tagged) - Human CDC-like kinase 2 (CLK2) |
CNY 5,256.00 |
|
| SC323449 | CLK2 (untagged)-Kinase deficient mutant (K192M) of Human CDC-like kinase 2 (CLK2) |
CNY 3,656.00 |
