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CBS (NM_000071) Human Untagged Clone
CAT＃: SC128074
CBS (untagged)-Human cystathionine-beta-synthase (CBS), transcript variant 1
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CBSL; HIP4 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000071.1
CAGCCGCTCGCCCCTCTTTTCCATGTATCCGTCCAGGATCCCATGACAGATTCTGTTGTC
ACGTCTCCTTACAGAGTTTGAGCGGTGCTGAACTGTCAGCACCATCTGTCCGGTCCCAGC ATGCCTTCTGAGACCCCCCAGGCAGAAGTGGGGCCCACAGGCTGCCCCCACCGCTCAGGG CCACACTCGGCGAAGGGGAGCCTGGAGAAGGGGTCCCCAGAGGATAAGGAAGCCAAGGAG CCCCTGTGGATCCGGCCCGATGCTCCGAGCAGGTGCACCTGGCAGCTGGGCCGGCCTGCC TCCGAGTCCCCACATCACCACACTCCCCCGGCAAAATCTCCAAAAATCTTGCCAGATATT CTGAAGAAAATCGGGGACACCCCTATGGTCAGAATCAACAAGATTGGGAAGAAGTTCGGC CTGAAGTGTGAGCTCTTGGCCAAGTGTGAGTTCTTCAACGCGGGCGGGAGCGTGAAGGAC CGCATCAGCCTGCGGATGATTGAGGATGCTGAGCGCGACGGGACGCTGAAGCCCGGGGAC ACGATTATCGAGCCGACATCCGGGAACACCGGGATCGGGCTGGCCCTGGCTGCGGCAGTG AGGGGCTATCGCTGCATCATCGTGATGCCAGAGAAGATGAGCTCCGAGAAGGTGGACGTG CTGCGGGCACTGGGGGCTGAGATTGTGAGGACGCCCACCAATGCCAGGTTCGACTCCCCG GAGTCACACGTGGGGGTGGCCTGGCGGCTGAAGAACGAAATCCCCAATTCTCACATCCTA GACCAGTACCGCAACGCCAGCAACCCCCTGGCTCACTACGACACCACCGCTGATGAGATC CTGCAGCAGTGTGATGGGAAGCTGGACATGCTGGTGGCTTCAGTGGGCACGGGCGGCACC ATCACGGGCATTGCCAGGAAGCTGAAGGAGAAGTGTCCTGGATGCAGGATCATTGGGGTG GATCCCGAAGGGTCCATCCTCGCAGAGCCGGAGGAGCTGAACCAGACGGAGCAGACAACC TACGAGGTGGAAGGGATCGGCTACGACTTCATCCCCACGGTGCTGGACAGGACGGTGGTG GACAAGTGGTTCAAGAGCAACGATGAGGAGGCGTTCACCTTTGCCCGCATGCTGATCGCG CAAGAGGGGCTGCTGTGCGGTGGCAGTGCTGGCAGCACGGTGGCGGTGGCCGTGAAGGCC GCGCAGGAGCTGCAGGAGGGCCAGCGCTGCGTGGTCATTCTGCCCGACTCAGTGCGGAAC TACATGACCAAGTTCCTGAGCGACAGGTGGATGCTGCAGAAGGGCTTTCTGAAGGAGGAG GACCTCACGGAGAAGAAGCCCTGGTGGTGGCACCTCCGTGTTCAGGAGCTGGGCCTGTCA GCCCCGCTGACCGTGCTCCCGACCATCACCTGTGGGCACACCATCGAGATCCTCCGGGAG AAGGGCTTCGACCAGGCGCCCGTGGTGGATGAGGCGGGGGTAATCCTGGGAATGGTGACG CTTGGGAACATGCTCTCGTCCCTGCTTGCCGGGAAGGTGCAGCCGTCAGACCAAGTTGGC AAAGTCATCTACAAGCAGTTCAAACAGATCCGCCTCACGGACACGCTGGGCAGGCTCTCG CACATCCTGGAGATGGACCACTTCGCCCTGGTGGTGCACGAGCAGATCCAGTACCACAGC ACCGGGAAGTCCAGTCAGCGGCAGATGGTGTTCGGGGTGGTCACCGCCATTGACTTGCTG AACTTCGTGGCCGCCCAGGAGCGGGACCAGAAGTGAAGTCCGGAGAGCTGGGCGGTGCGG AGCGGGCCCGCCACCCTTGCCCACTTCTCCTTCGCTTTCCTGAGCCCTAAACACACGCGT GATTGGTAACTGCCTGGCACCGTTATCCCTGCAGACGGCACAGAGCATCCGTCTCCCCTC GTTAACACATGGCTTCCTAAATGGCCCTGTTTACGGCCTATGAGATGAAATATGTGATTT TCTCTAATGTAACTTCCTCTTAGGATGTTTCACCAAGGAAATATTGAGAGAGAAGTCGGC CAGGTAGGATGAACACAGGCAATGACTGCACAGAGTGGATTAAAGGCAAAAGAGAGAAGA GTCCAGGAAGGGGCGGGGAGAAGCCTGGGTGGCTCAGCATCCTCCACGGGCTGCGCCGTC TGCTCGGGGCTGAGCTGGCGGGAGCAGTTTGCGTGTTTGGGTTTTTTAATTGAGATGAAA TTCAAATAACCTAAAAATCAATCACTTGAAAGTGAACAATCAGCGGCATTTAGTACATCC AGAAAGTTGTGTAGGCACCACCTCTGTCACGTTCTGGAACATTCTGTCATCACCCCGTGA AGCAATCATTTCCCCTCCCGTCTTCCTCCTCCCCTGGCAACTGCTGATCGACTTTGTGTC TCTGTTGTCTAAAATAGGTTTTCCCTGTTCTGGACATTTCATATAAATGGAATCACACAA AAAAAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000071 |
| Insert Size | 2360 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000071.1, NP_000062.1 |
| RefSeq Size | 2544 bp |
| RefSeq ORF | 1656 bp |
| Locus ID | 875 |
| UniProt ID | P35520 |
| Domains | CBS, PALP |
| Protein Families | Druggable Genome |
| Protein Pathways | Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Selenoamino acid metabolism |
| Gene Summary | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201755 | CBS (Myc-DDK-tagged)-Human cystathionine-beta-synthase (CBS), transcript variant 1 |
CNY 4,104.00 |
|
| RC201755L1 | Lenti ORF clone of Human cystathionine-beta-synthase (CBS), transcript variant 1, Myc-DDK-tagged |
CNY 6,504.00 |
|
| RC201755L2 | Lenti ORF clone of Human cystathionine-beta-synthase (CBS), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201755L3 | Lenti ORF clone of Human cystathionine-beta-synthase (CBS), transcript variant 1, Myc-DDK-tagged |
CNY 6,504.00 |
|
| RC201755L4 | Lenti ORF clone of Human cystathionine-beta-synthase (CBS), transcript variant 1, mGFP tagged |
CNY 6,504.00 |
|
| RG201755 | CBS (tGFP-tagged) - Human cystathionine-beta-synthase (CBS), transcript variant 1 |
CNY 5,704.00 |
|
| SC324364 | CBS (untagged)-Human cystathionine-beta-synthase (CBS), transcript variant 1 |
CNY 4,112.00 |
