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Dishevelled 2 (DVL2) (NM_004422) Human Untagged Clone
CAT＃: SC128046
DVL2 (untagged)-Human dishevelled, dsh homolog 2 (Drosophila) (DVL2)
CNY 5,400.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128046 sequence for NM_004422 edited (data generated by NextGen Sequencing)
ATGGCGGGTAGCAGCACTGGGGGCGGTGGGGTTGGGGAGACGAAGGTGATTTACCACCTG GATGAGGAAGAGACTCCCTACCTGGTGAAGATCCCTGTCCCCGCCGAGCGCATCACCCTC GGCGATTTCAAGAGCGTCCTGCAGCGGCCCGCGGGCGCCAAGTACTTTTTCAAGTCTATG GATCAGGATTTCGGGGTGGTGAAGGAAGAAATTTCAGATGACAACGCCCGCCTCCCCTGC TTCAACGGAAGGGTGGTATCCTGGCTGGTGTCCTCAGATAATCCCCAACCCGAGATGGCC CCTCCAGTCCATGAGCCTCGGGCAGAACTGGCGCCTCCAGCCCCACCTTTACCTCCTTTG CCACCCGAGAGGACCAGCGGCATTGGGGACTCAAGGCCTCCATCCTTCCACCCTAATGTG TCCAGCAGCCATGAGAATCTGGAGCCTGAGACAGAAACCGAGTCAGTAGTGTCACTGAGG CGGGAGCGGCCTCGCAGGAGAGACAGCAGTGAGCATGGCGCTGGGGGCCACAGGACTGGT GGCCCCTCAAGGCTGGAGCGCCACCTGGCCGGATACGAGAGCTCCTCTACCCTCATGACC AGCGAGCTGGAGAGTACCAGCCTGGGGGACTCGGACGAGGAGGACACCATGAGCAGGTTC AGCAGCTCCACGGAGCAGAGCAGTGCCTCCCGCCTCCTTAAGCGCCACCGGCGGCGAAGG AAGCAGAGGCCACCCCGCCTGGAGAGGACGTCATCCTTCAGCAGCGTCACAGATTCCACA ATGTCTCTCAATATCATCACAGTCACGCTAAACATGGAGAAGTACAACTTCCTGGGTATC TCCATTGTTGGCCAGAGCAATGAGCGGGGAGACGGAGGCATCTACATTGGCTCCATCATG AAGGGTGGGGCTGTGGCGGCCGACGGGCGCATTGAGCCAGGGGACATGCTTTTGCAGGTG AATGACATGAACTTTGAGAACATGAGCAACGATGACGCTGTGCGGGTGCTGAGGGACATT GTGCACAAGCCTGGCCCCATTGTGCTGACTGTGGCCAAGTGCTGGGATCCCTCTCCTCAG GCCTATTTCACTCTCCCCCGAAATGAGCCCATCCAGCCAATTGACCCTGCTGCCTGGGTG TCCCATTCCGCGGCTCTGACTGGCACCTTCCCAGCCTATCCAGGTTCCTCCTCCATGAGC ACCATTACATCTGGATCGTCTTTGCCTGATGGCTGTGAAGGCCGGGGTCTCTCCGTCCAT ACGGACATGGCATCGGTGACCAAGGCCATGGCAGCTCCAGAGTCTGGACTGGAAGTCCGG GACCGCATGTGGCTCAAGATCACCATCCCTAATGCCTTTCTGGGCTCGGATGTGGTTGAC TGGCTCTACCATCACGTGGAGGGCTTTCCTGAGCGGCGGGAGGCCCGCAAGTATGCCAGC GGGCTGCTCAAAGCAGGCCTGATCCGACACACCGTCAACAAGATCACCTTCTCTGAGCAG TGCTATTACGTCTTCGGAGACCTCAGTGGTGGCTGTGAGAGCTACCTAGTCAACCTGTCT CTCAATGACAACGATGGCTCCAGTGGGGCTTCAGACCAGGATACCCTGGCTCCTCTGCCT GGGGCCACCCCCTGGCCCCTGCTGCCCACTTTCTCCTACCAATACCCTGCCCCACACCCC TACAGCCCGCAGCCTCCACCCTACCATGAGCTTTCATCTTACACCTATGGTGGGGGCAGT GCCAGCAGCCAGCATAGTGAGGGCAGCCGGAGCAGTGGGTCGACACGGAGTGATGGGGGG GCAGGGCGCACGGGGAGGCCCGAGGAGCGGGCCCCCGAGTCCAAGTCCGGCAGTGGCAGT GAGTCTGAGCCCTCCAGCCGAGGGGGCAGCCTTCGGCGGGGTGGGGAAGCAAGTGGGACT AGCGATGGGGGCCCTCCTCCATCCAGAGGCTCAACTGGGGGTGCCCCTAATCTCCGAGCC CACCCAGGGCTCCATCCCTATGGACCGCCCCCTGGCATGGCCCTCCCCTACAACCCCATG ATGGTGGTCATGATGCCCCCACCTCCACCTCCAGTCCCTCCAGCAGTGCAGCCTCCGGGG GCCCCTCCAGTCAGAGACCTGGGCTCTGTGCCCCCAGAACTGACAGCCAGCCGCCAAAGC TTCCACATGGCCATGGGCAATCCCAGCGAGTTCTTTGTGGATGTTATGTAG Clone variation with respect to NM_004422.2 >OriGene 5' read for NM_004422 unedited
GCCACAGGAGCTACACGAATACCACAGGGCGGCCGCGAAACGGCACGAGGGGGCGGCGGA GCCCGGGAGCGCGCGGGCGAGACACGGCGGGAAGCAGCACCGGGGGCGGCGGGGACGGGG AGACGAAGGCGATCTACCACCTGGATGAGGAAGAGACTCCCTACCTGGTGAAGACCCCTG TCCCCGCCGAGCGCATCACCCTCGGCGATTTCAAGAGCGTCCTGCAGCGGCCCGCGGGCG CCAAGTACTTTTTCAAGTCTATGGATCAGGATTTCGGGGTGGTGAAGGAAGAAATTTCAG ATGACAACGCCCGCCTCCCCTGCTTCAACGGAAGGGTGGTATCCTGGCTGGTGTCCTCAG ATAATCCCCAACCCGAGATGGCCCCTCCAGTCCATGAGCCTCGGGCAGAACTGGCGCCTC CAGCCCCACCTTTACCTCCTTTGCCACCCGAGAGGACCAGCGGCATTGGGGACTCAAGGC CTCCATCCTTCCACCCTAATGTGTCCAGCAGCCATGAGAATCTGGAGCCTGAGACAGAAA CCGAGTCAGTAGTGTCACTGAGGCGGGAGCGGCCTCGCAGGAGAGACAGCAGTGAGCATG GCGCTGGGGGCCACAGGACTGGTGGCCCCTCAAGGCTGGAGCGCCACCTGGCCGGATACG AGAGCTCCTCTACCCTCATGACCAGCGAGCTGGAGAGTACCAGCCTGGGGGACTCGGACG AGAGGACACCATGAGCAGTTCAGCAGCTCCACGGAGCAGAGCAGTGCCTCCCGCCTCCTT AAGCGCCACCGGCGGCGAAGAAGCAGAGGCCACCCCCGCCTGAGAGGACGTCATCCTTCA GCAGCGTCACAGATTCCACAATGTCTCTCATATCATCACAGTCACGCTAAACATGGAGAA GTACACTTCCTGGGTATCTCCATTGTTGGCCAGAGCAATGAGCGGGGGAGACGAAGCATC TACA >Forward primer walk for NM_004422 unedited
GGGGCCCCTTCCATCCATCCTCCTCATGCAGCCTCCGGGGCCCCTCCATCAGAGACCTGG GCTCTGTGCCCCCANAACTGACAGCCAGCCGCCAAAGCTTCCACATGGCCATGGGCAATC CCAGCGAGTTCTTTGTGGATGTTATGTAGCCCACTGTGGGGCCAGGCTGGGCCGGGCGCT CCTGGTGTGTGACTGGGTGTCCTGGCCGTCATGTGCTTGCTCTTACAGTGCCTGGGCTCA GCCTACCAGCTGCTGCCATACAGGAGATTGTGGCCACTGTGACTCTCACCAGCAGTGCCT GGTTCCTCCCCCTTCCCTCAGGGGTAGACAAGGGACCTTTGATTATTTTTAGCTTTGTTT TTTTATAAGCCTTTTTGGGGGTTAAAATAGAGTTTCTTACATTTTTGGGACTTTTTTAAT AGGCATTTCCTCTTTTATATGAAGAATTCCCATCCATTGGGCCCCTTCTAACCCCAGAAT GTGACCTCCTCCTCCAGTTACCCACAGCCCTGCCCTTTGCAGGGTTGGGGGTGGTCAGCG GTACCCCGGGGTTAGGCATCCTAGACAGCAGCCTGAGGAAGCTGGGAGATTTGGGCCATG TAGCTGCCTTTGTTACTCTATTTATTTTAGTCACTTGTATAAAACACCAAATAAAGCAAT AGAGGCAAACTCAAAANANAAAAANGACAAGAAGGAAGGTGCGGAGGGCAAACCTGCGCC ACACACAAAAAATCCAACACAAGAAAGACCCAAAGAAAANAAGAAGCGAGACAACCCCAC CTAAATAAAGAAAACTTCTTTTTTGTTTGGGGGCCGGGACAATTATTTTTTCCAAAAAAA ATCCGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004422 |
| Insert Size | 3050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004422.2, NP_004413.1 |
| RefSeq Size | 3046 bp |
| RefSeq ORF | 2211 bp |
| Locus ID | 1856 |
| UniProt ID | O14641 |
| Domains | DEP, DAX, PDZ, Dishevelled |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway |
| Gene Summary | This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation
,null,
The Journal of Biological Chemistry
,PubMed ID 36965619
[DVL2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202233 | DVL2 (Myc-DDK-tagged)-Human dishevelled, dsh homolog 2 (Drosophila) (DVL2) |
CNY 5,392.00 |
|
| RC202233L1 | Lenti ORF clone of Human dishevelled, dsh homolog 2 (Drosophila) (DVL2), Myc-DDK-tagged |
CNY 7,792.00 |
|
| RC202233L2 | Lenti ORF clone of Human dishevelled, dsh homolog 2 (Drosophila) (DVL2), mGFP tagged |
CNY 7,700.00 |
|
| RC202233L3 | Lenti ORF clone of Human dishevelled, dsh homolog 2 (Drosophila) (DVL2), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC202233L4 | Lenti ORF clone of Human dishevelled, dsh homolog 2 (Drosophila) (DVL2), mGFP tagged |
CNY 7,700.00 |
|
| RG202233 | DVL2 (tGFP-tagged) - Human dishevelled, dsh homolog 2 (Drosophila) (DVL2) |
CNY 6,992.00 |
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