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Signal peptide peptidase like 2B (SPPL2B) (NM_152988) Human Untagged Clone
CAT＃: SC127928
SPPL2B (untagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2
CNY 2,950.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMP-4; IMP4; PSH4; PSL1 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127928 sequence for NM_152988 edited (data generated by NextGen Sequencing)
ATGGCGGCAGCGGTGGCGGCTGCGCTGGCGCGGCTTTTGGCGGCCTTTCTGCTCCTCGCG GCCCAGGTGGCCTGTGAGTACGGCATGGTGCACGTGGTCTCCCAGGCCGGGGGCCCCGAA GGCAAAGACTACTGCATCCTCTACAACCCGCAGTGGGCCCATCTTCCGCACGACCTCAGC AAGGCATCTTTCCTGCAGCTGCGCAACTGGACGGCCTCCCTGCTCTGCTCCGCAGCCGAC CTCCCCGCCCGTGGCTTCAGCAACCAGATCCCGCTGGTGGCGCGGGGGAACTGCACCTTC TATGAGAAAGTGAGGCTGGCCCAGGGCAGCGGAGCACGCGGGCTGCTCATCGTCAGCAGG GAGAGGCTGGTCCCCCCGGGGGGTAATAAGACGCAGTATGATGAGATTGGCATTCCCGTG GCCCTGCTCAGCTACAAAGACATGCTGGACATCTTCACGCGTTTCGGCCGCACGGTGAGG GCGGCGCTGTATGCGCCTAAGGAGCCGGTGCTGGACTACAACATGGTCATCATCTTCATC ATGGCTGTGGGCACCGTCGCCATCGGCGGCTACTGGGCCGGGAGTCGGGACGTGAAGAAA AGGTACATGAAGCACAAGCGCGACGATGGGCCCGAGAAGCAGGAGGACGAGGCGGTGGAC GTGACGCCGGTGATGACCTGCGTGTTTGTGGTGATGTGCTGCTCCATGCTGGTGCTGCTC TACTATTTCTACGACCTCCTCGTGTACGTGGTCATCGGGATCTTCTGCCTGGCCTCCGCC ACCGGCCTCTACAGCTGCCTGGCGCCCTGTGTGCGGCGGCTGCCCTTCGGCAAGTGCAGG ATCCCCAACAACAGCCTGCCCTACTTCCACAAGCGCCCGCAGGCCCGTATGCTGCTCCTG GCGCTCTTCTGCGTGGCCGTCAGCGTGGTGTGGGGCGTCTTCCGCAACGAGGACCAGTGG GCCTGGGTCCTCCAGGATGCCCTGGGCATCGCCTTCTGCCTCTACATGCTGAAGACCATC CGTCTGCCCACCTTCAAGGCCTGCACGCTGCTGCTGCTGGTGCTGTTCCTCTACGACATC TTCTTCGTGTTCATCACGCCCTTCCTGACCAAGAGTGGGAGCAGCATCATGGTGGAGGTG GCCACTGGGCCCTCGGACTCAGCCACCCGTGAGAAGCTGCCCATGGTCCTGAAGGTGCCC AGGCTGAACTCCTCACCTCTGGCCCTGTGTGACCGGCCCTTCTCCCTCCTGGGTTTCGGA GACATTTTGGTGCCAGGGCTGCTGGTGGCCTACTGCCACAGGTTTGACATCCAGGTACAG TCCTCCAGGGTATACTTCGTGGCCTGCACCATCGCCTATGGCGTTGGCCTCCTTGTGACA TTCGTGGCACTGGCCCTGATGCAGCGTGGCCAGCCCGCTCTCCTCTACCTGGTGCCCTGC ACGCTGGTGACGAGCTGCGCTGTGGCGCTCTGGCGCCGGGAGCTGGGCGTGTTCTGGACG GGCAGCGGCTTTGCGAAAGTCCTACCTCCATCTCCGTGGGCCCCAGCACCAGCCGACGGC CCGCAGCCTCCCAAAGACTCTGCCACGCCACTCTCCCCGCAGCCGCCCAGCGAAGAACCA GCCACATCCCCCTGGCCTGCTGAGCAGTCCCCAAAATCACGCACGTCCGAGGAGATGGGG GCTGGAGCCCCCATGCGGGAGCCTGGGAGCCCAGCTGAATCAGAGGGCCGGGACCAGGCC CAGCCGTCCCCGGTAACCCAGCCTGGCGCCTCGGCCTAG Clone variation with respect to NM_152988.2 735 t=>c;1722 c=>a >OriGene 5' read for NM_152988 unedited
CCCCATTACCCCGCCCGTTGCCGCAAAGGGCGGCAGGCGTGTACGGTGGGAGGTCTATAT AAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGC CGCGAATTCGGCACGAGGCCGGCCGACATGGCGGCAGCGGTGGCGGCTTCGCTGGCGCGG CTTTTGGCGGCCTTTCTGCTCCTCGCGGCCCAGGTGGCCTGTGAGTACGGCATGGTGCAC GTGGTCTCCCAGGCCGGGGGCCCCGAAGGCAAAGACTACTGCATCCTCTACAACCCGCAG TGGGCCCATCTTCCGCACGACCTCAGCAAGGCATCTTTCCTGCAGCTGCGCAACTGGACG GCCTCCCTGCTCTGATCCGCAGCCGACCTCCCCGCCCGTGGCTTCAGCAACCAGATCCTG CTGGTGGCGCGGNGGAACTGCACCTTCTATGAGCAAGTGAGGCTGGCCCAGGGCAGCGNA GCACGCGGGCTGCTCATCGTCAGCAGGGAGAGGCTGTCCCCCCCGGGGGGTAATAGACGC AGCATGAGGAGATTGGCATTCCCGGGCCCTTGTTAAGTTACAAAGACCTGCTTGGACATT TTTACGGCGTTTCGGCCGCCCCGGGAAGGGCGGGCCTTTAATGGCCCTATAGGACCCGGG GGCTGGCCCACCCCCCGGGGCACCCACCTTCAAATAGGGCGTGGGGGCCCCGCCCCCATT TGGGGGTAAACTGGGCCCCGGGGNTCCCCCCTCTTAAAACAAGGTCCATTAAACCCCACC CCCCCAAATGGTCCCCCAAAAACAACAGGAACACAAGCGGGGGGAACAAAACCCCCCCGA AAACACCCCCTGTTTTTGGTGGAGAAAACTTCCCCCTCCCCGGNGGGGGGGATACAATAA TTAAAAACCCCCCCCN >OriGene 3' read for NM_152988 unedited
AGCCTGGGGNAGTGGGTCACAGGGNATGCCACCCGGGTTCTGTTCAGGAAAAGCTATGAC CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAGTTGCGACCATTTATT AAAATGGGGAGGAGTGTGCAGGCATGGCCAGGCACCTCTGGCTGAGGGCAGGGCAGGGCC TTAGCCAGGGGAGCAGCTTGTCCACTTACTGCCAGCCTTGTTCACGCCCCAAAACCCCGC CCCACGGGCCTGTCTCAGCCAGCGTCAGGGGCCAGAGGCCGCCCCGGCCACCGGTCCGTG TCCTAGGCTTGGAGGCAGCTTCCAAACCTCCCAGGGGCTCCGATCTGCTCAAGAGGGAAA AGCGATGCCTTCTGGGAGACAGAAAGCTGCTCTTCCACCCGGAGAGCAGGATGCCGTGGG GAGGGAGGTCACCTGAAGGCCGAAGCAGCTGGTGAGCACCAAGTGTGGCCGCGGCCAGAG TCCACCCACGCCTGCTCACTCATGCAGACGACGCTTGAGGGTCTGCAGAGAGGCCGGGCA GGGCCTGCGAGGACGGACCCCGGTGGGGAGGATGGACCCGCAGAGAGCTTGTGGCAGCCG GGCGAGCTGGGAGCAGCAGGCGTGCAGCCGGNGCAGCTGGGCTGGGCGCGGGCACAGACC GCAGGGGTCTCGGCNAGGATGAGCACCATGTTGGGGCGGGTGGGGACGGCACAGGCCTCG GTCCCGGNGGACAGGCGTCTGTCTGTCTGTCTCCAGTGGGCGCCAGGCAGCCCCAAATCC TGGTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_152988 |
| Insert Size | 2900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152988.1, NP_694533.1 |
| RefSeq Size | 2557 bp |
| RefSeq ORF | 1779 bp |
| Locus ID | 56928 |
| UniProt ID | Q8TCT7 |
| Protein Families | Protease, Transmembrane |
| Gene Summary | This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) represents the shorter transcript but encodes the longer isoform (2). |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223590 | SPPL2B (Myc-DDK-tagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 3,990.00 |
|
| RC223590L3 | Lenti-ORF clone of SPPL2B (Myc-DDK-tagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 5,890.00 |
|
| RC223590L4 | Lenti-ORF clone of SPPL2B (mGFP-tagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 5,890.00 |
|
| RG223590 | SPPL2B (tGFP-tagged) - Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 4,370.00 |
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