United States
Germany
Japan
United Kingdom
China
Signal peptide peptidase like 2B (SPPL2B) (NM_152988) Human Tagged ORF Clone
CAT＃: RC223590
- TrueORF®
SPPL2B (Myc-DDK-tagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2
ORF Plasmid: tGFP
"NM_152988" in other vectors (4)
Need custom modification / cloning service?
Get a free quote
CNY 3,990.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | IMP-4; IMP4; PSH4; PSL1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC223590 representing NM_152988
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCAGCGGTGGCGGCTGCGCTGGCGCGGCTTTTGGCGGCCTTTCTGCTCCTCGCGGCCCAGGTGG CCTGTGAGTACGGCATGGTGCACGTGGTCTCCCAGGCCGGGGGCCCCGAAGGCAAAGACTACTGCATCCT CTACAACCCGCAGTGGGCCCATCTTCCGCACGACCTCAGCAAGGCATCTTTCCTGCAGCTGCGCAACTGG ACGGCCTCCCTGCTCTGCTCCGCAGCCGACCTCCCCGCCCGTGGCTTCAGCAACCAGATCCCGCTGGTGG CGCGGGGGAACTGCACCTTCTATGAGAAAGTGAGGCTGGCCCAGGGCAGCGGAGCACGCGGGCTGCTCAT CGTCAGCAGGGAGAGGCTGGTCCCCCCGGGGGGTAATAAGACGCAGTATGATGAGATTGGCATTCCCGTG GCCCTGCTCAGCTACAAAGACATGCTGGACATCTTCACGCGTTTCGGCCGCACGGTGAGGGCGGCGCTGT ATGCGCCTAAGGAGCCGGTGCTGGACTACAACATGGTCATCATCTTCATCATGGCTGTGGGCACCGTCGC CATCGGCGGCTACTGGGCCGGGAGTCGGGACGTGAAGAAAAGGTACATGAAGCACAAGCGCGACGATGGG CCCGAGAAGCAGGAGGACGAGGCGGTGGACGTGACGCCGGTGATGACCTGCGTGTTTGTGGTGATGTGCT GCTCCATGCTGGTGCTGCTCTACTACTTCTACGACCTCCTCGTGTACGTGGTCATCGGGATCTTCTGCCT GGCCTCCGCCACCGGCCTCTACAGCTGCCTGGCGCCCTGTGTGCGGCGGCTGCCCTTCGGCAAGTGCAGG ATCCCCAACAACAGCCTGCCCTACTTCCACAAGCGCCCGCAGGCCCGTATGCTGCTCCTGGCGCTCTTCT GCGTGGCCGTCAGCGTGGTGTGGGGCGTCTTCCGCAACGAGGACCAGTGGGCCTGGGTCCTCCAGGATGC CCTGGGCATCGCCTTCTGCCTCTACATGCTGAAGACCATCCGTCTGCCCACCTTCAAGGCCTGCACGCTG CTGCTGCTGGTGCTGTTCCTCTACGACATCTTCTTCGTGTTCATCACGCCCTTCCTGACCAAGAGTGGGA GCAGCATCATGGTGGAGGTGGCCACTGGGCCCTCGGACTCAGCCACCCGTGAGAAGCTGCCCATGGTCCT GAAGGTGCCCAGGCTGAACTCCTCACCTCTGGCCCTGTGTGACCGGCCCTTCTCCCTCCTGGGTTTCGGA GACATTTTGGTGCCAGGGCTGCTGGTGGCCTACTGCCACAGGTTTGACATCCAGGTACAGTCCTCCAGGG TATACTTCGTGGCCTGCACCATCGCCTATGGCGTTGGCCTCCTTGTGACATTCGTGGCACTGGCCCTGAT GCAGCGTGGCCAGCCCGCTCTCCTCTACCTGGTGCCCTGCACGCTGGTGACGAGCTGCGCTGTGGCGCTC TGGCGCCGGGAGCTGGGCGTGTTCTGGACGGGCAGCGGCTTTGCGAAAGTCCTACCTCCATCTCCGTGGG CCCCAGCACCAGCCGACGGCCCGCAGCCTCCCAAAGACTCTGCCACGCCACTCTCCCCGCAGCCGCCCAG CGAAGAACCAGCCACATCCCCCTGGCCTGCTGAGCAGTCCCCAAAATCACGCACGTCCGAGGAGATGGGG GCTGGAGCCCCCATGCGGGAGCCTGGGAGCCCAGCTGAATCCGAGGGCCGGGACCAGGCCCAGCCGTCCC CGGTAACCCAGCCTGGCGCCTCGGCC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA >RC223590 representing NM_152988
Red=Cloning site Green=Tags(s) MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKASFLQLRNW TASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNKTQYDEIGIPV ALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKRDDG PEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCR IPNNSLPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTL LLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVAL WRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMG AGAPMREPGSPAESEGRDQAQPSPVTQPGASA SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_152988 |
| ORF Size | 1776 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152988.1, NP_694533.1 |
| RefSeq Size | 2557 bp |
| RefSeq ORF | 1779 bp |
| Locus ID | 56928 |
| UniProt ID | Q8TCT7 |
| Protein Families | Protease, Transmembrane |
| MW | 64.5 kDa |
| Gene Summary | This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223590L3 | Lenti-ORF clone of SPPL2B (Myc-DDK-tagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 5,890.00 |
|
| RC223590L4 | Lenti-ORF clone of SPPL2B (mGFP-tagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 5,890.00 |
|
| RG223590 | SPPL2B (tGFP-tagged) - Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 6,448.00 |
|
| SC127928 | SPPL2B (untagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 2 |
CNY 4,416.00 |
其它Signal peptide peptidase like 2B产品
