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KLF2 (NM_016270) Human Untagged Clone
CAT＃: SC127849
KLF2 (untagged)-Human Kruppel-like factor 2 (lung) (KLF2)
CNY 3,656.00
| Cited in 6 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LKLF |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127849 sequence for NM_016270 edited (data generated by NextGen Sequencing)
ATGGCGCTGAGTGAACCCATCCTGCCGTCCTTCTCCACTTTCGCCAGCCCGTGCCGCGAG CGCGGCCTGCAGGAGCGCTGGCCGCGCGCCGAACCCGAGTCCGGCGGCACCGACGACGAC CTCAACAGCGTGCTGGACTTCATCCTGTCCATGGGGCTGGATGGCCTGGGCGCCGAGGCC GCCCCGGAGCCGCCGCCGCCGCCCCCGCCGCCTGCGTTCTATTACCCCGAACCCGGCGCG CCCCCGCCCTACAGCGCCCCCGCGGGTGGCCTGGTGTCTGAGCTGCTGCGACCCGAGCTG GATGCGCCGCCGGGGCCCGCACTGCACGGCCGCTTTCTGCTGGCGCCGCCCGGCCGCCTG GTCAAGGCCGAGCCCCCTGAAGCGGACGGCGGCGGCGGCTACGGCTGCGCCCCCGGGCTG ACCCGTGGACCGCGCGGCCTCAAGCGCGAGGGCGCCCCGGGCCCGGCGGCTTCGTGCATG CGAGGTCCCGGGGGCCGCCCCCCGCCGCCGCCCGACACACCGCCGCTCAGCCCCGACGGC CCCGCGCGCCTGCCCGCGCCCGGTCCGCGCGCCTCCTTCCCGCCGCCTTTCGGTGGCCCT GGTTTCGGCGCGCCCGGGCCCGGCCTGCATTACGCGCCGCCTGCGCCCCCAGCCTTCGGT CTCTTCGACGACGCGGCCGCCGCCGCGGCAGCCCTGGGCCTGGCGCCCCCCGCCGCCCGC GGTCTCCTCACGCCGCCTGCGTCCCCGCTGGAGCTGCTGGAGGCCAAGCCAAAGCGCGGC CGCCGCTCTTGGCCCCGCAAACGCACCGCCACTCACACCTGCAGCTACGCGGGCTGCGGC AAGACCTACACCAAGAGTTCGCATCTGAAGGCGCATCTGCGCACGCACACAGGTGAGAAG CCCTACCACTGCAACTGGGACGGCTGCGGCTGGAAGTTTGCGCGCTCAGACGAGCTCACG CGCCACTACCGAAAGCACACGGGCCACCGGCCATTCCAGTGCCATCTGTGCGATCGTGCC TTCTCGCGCTCCGATCACCTGGCGCTGCACATGAAACGGCACATGTAG Clone variation with respect to NM_016270.2 311 t=>c >OriGene 5' read for NM_016270 unedited
CCTTCGCGCCCGTTGCCGCTTTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA GAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAA TTCGGCACCAGGCCCGCCCGCGCCCCGACCAGCCCGGCCTCGGGCAGCCACTCACCGGTG TCCCCGTCCGCGTCCTTCCTCCCCGGGTCCCGGCCATGGCGCTGAGTGAACCCATCCTGC CGTCCTTCTCCACTTTCGCCAGCCCGTGCCGCGAGCGCGGCCTGCAGGAGCGCTGGCCGC GCGCCGAACCCGAGTCCGGCGGCACCGACGACGACCTCAACAGCGTGCTGGACTTCATCC TGTCCATGGGGCTGGATGGCCTGGGCGCCGAGGCCGCCCCGGAGCCGCCGCCGCCGCCCC CGCCGCCTGCGTTCTATTACCCCGAACCCGGCGCGCCCCCGCCCTACAGCGCCCCCGCGG GTGGCCTGGTGTCTGAGCTGCTGCGACCCGAGCTGGATGCGCCGCCGGGGCCCGCACTGC ACGGCCGCTTTCTGCTGGCGCCGCCCGGCCGCCTGGTCAAGGCCGAGCCCCCTGAAGCGG ACGGCGGCGGCGGCTACGGCTGCGCCCCCGGGCTGACCCGTGGACCGCGCGGCCTCAAGC GCGAGGGCGCCCCGGGCCCGGCGGCTTCGTGCATGCGAGGTCCCGGGGGCCGNCCCCCGC CGCCGCCCGACACACCGNCGCTCAGCCCCGACGGCCCCGCGCGCCTGCCCGCGCCCGGGT CGNNGCGCTTCTTCCCCGCCGCTTTCGGTGGCCCTGGNTTTTCGCGCGCCCGGGCCCGGC CTGCATTACGCGCCGCCTGCGCCCCAGCCTTCGGTCTCTTCGACGACGCGCCGNCGCCGC GGCAGCCCTGGGCCTGGCGCCCCCGCCGCCCGCC >OriGene 3' read for NM_016270 unedited
NGAGCACTGGGGNNAGGGGTCACAGGGNATGCCACCCGGGCTCTGTTCAGGAAACAGCTA TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTAAAAAGATGCAAAACTTTTTAATAAAAAAAAAAACCAACCCAGCAAAATTTTA TAAAAACGAACCAGGTTGCCCAAAAATGCCCACCTGTCTTTTTATGTACAGTAATACAAT ATTTGTCAGTCACTTTTTACAATTTTATAAAAAATGCCGCAAACAGTACAAATTAAGGCC CTTATTTCTCACAAGGCATCACAAGCCTCGATCCTTTAGTGTAAACCCGGTGGGAGAGAA GATGCCACTTAAATTATTGCACCATTTTGAAAAACAAAACTCGTCAAGGAGGATCGTGGT CTTTTCCCACCGGGCCTTCAGTCACAAACGGGGGCTGGGGTGGTGGCGTCNTCNTCGTCG TCATCGAGGGAGACCCTCTGTAGCCACGCTGTGCCCGGCCCGGTTCTCTGGGTCCAATAA ATACCANTCACAGTTTGGGAGGGGGCCCGCGCCCGGGCCGTGGGACCCGCCACGGCCCCG CGCAGGTGGGGCGGGGGGCCTCCCGGCTACATGTTGCCGTTTCATGTGCAACGCCCGGGT AATCCGAACGCCGAGAAGGGCCCATTCGCCCCAAATGGCACTTGAATGGGCCCGGTGGCC CCTGGTTGCTTTTCGGGTAGGGGGCGCGTGGGCCTTCTTTTGGAGCCCCCAAAATTTCCA GCCCAAACCCTTCCCATTTTGCAGGGGGTGGGGCTTTCTACCCTGTGTTGGGGGGCCCAA ATTCCCCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016270 |
| Insert Size | 1068 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016270.2, NP_057354.1 |
| RefSeq Size | 1655 bp |
| RefSeq ORF | 1068 bp |
| Locus ID | 10365 |
| UniProt ID | Q9Y5W3 |
| Domains | zf-C2H2 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in the promoter of target genes to activate their transcription. It plays a role in many processes during development and disease including adipogenesis, embryonic erythropoiesis, epithelial integrity, inflammation and t-cell viability. [provided by RefSeq, Mar 2017] |
Citations (6)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Suppression of tumor metastasis by a RECK-activating small molecule
,null,
Scientific Reports
,PubMed ID 35149728
[KLF2]
|
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A functional screen identifies transcriptional networks that regulate HIV-1 and HIV-2
,Pedro, K;Agosto, L;Sewell, J;Eberenz, K;He, X;Fuxman Bass, J;Henderson, A;,
Proceedings of the National Academy of Sciences
,PubMed ID 33836568
[KLF2]
|
|
Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
,Sindi, HA;Russomanno, G;Satta, S;Abdul-Salam, VB;Jo, KB;Qazi-Chaudhry, B;Ainscough, AJ;Szulcek, R;Jan Bogaard, H;Morgan, CC;Pullamsetti, SS;Alzaydi, MM;Rhodes, CJ;Piva, R;Eichstaedt, CA;Grünig, E;Wilkins, MR;Wojciak-Stothard, B;,
Nat Commun
,PubMed ID 32132543
[KLF2]
|
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Simvastatin-Induced Sphingosine 1− Phosphate Receptor 1 Expression is KLF2-Dependent in Human Lung Endothelial Cells
,Sun, X;Mathew, B;Sammani, S;Jacobson, JR;Garcia, JG;,
Pulmonary Circulation
[KLF2]
|
|
The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma
,Piva, R;Deaglio, S;Famà, R;Buonincontri, R;Scarfò, I;,
Leukemia
,PubMed ID 25283840
[KLF2]
|
|
FOXO1 impairs whereas statin protects endothelial function in diabetes through reciprocal regulation of Krüppel-like factor 2
,Hae-Young Lee, Seock-Won Youn, Hyun-Jai Cho, Yoo-Wook Kwon, Sae-Won Lee, Sung-Jin Kim, Young-Bae Park, Byung-Hee Oh, and Hyo-Soo Kim,
Cardiovasc Res, Jan 2013; 97: 143 - 152.
[KLF2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210042 | KLF2 (Myc-DDK-tagged)-Human Kruppel-like factor 2 (lung) (KLF2) |
CNY 3,656.00 |
|
| RC210042L1 | Lenti ORF clone of Human Kruppel-like factor 2 (lung) (KLF2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210042L2 | Lenti ORF clone of Human Kruppel-like factor 2 (lung) (KLF2), mGFP tagged |
CNY 6,056.00 |
|
| RC210042L3 | Lenti ORF clone of Human Kruppel-like factor 2 (lung) (KLF2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210042L4 | Lenti ORF clone of Human Kruppel-like factor 2 (lung) (KLF2), mGFP tagged |
CNY 6,056.00 |
|
| RG210042 | KLF2 (tGFP-tagged) - Human Kruppel-like factor 2 (lung) (KLF2) |
CNY 5,256.00 |
