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OGDH (NM_002541) Human Untagged Clone
CAT＃: SC127702
OGDH (untagged)-Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 7,128.00
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AKGDH; E1k; KGD1; OGDC; OGDH2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127702 sequence for NM_002541 edited (data generated by NextGen Sequencing)
ATGTTTCATTTAAGGACTTGTGCTGCTAAGTTGAGGCCATTGACGGCTTCCCAGACTGTT AAGACATTTTCACAAAACAGACCAGCAGCAGCTAGGACATTTCAACAGATTCGGTGCTAT TCTGCACCTGTTGCTGCTGAGCCCTTTCTCAGTGGGACTAGTTCGAACTATGTGGAGGAG ATGTACTGTGCTTGGCTGGAAAACCCCAAAAGTGTACATAAGTCATGGGACATTTTTTTT CGCAACACGAATGCCGGAGCCCCACCGGGCACTGCCTACCAGAGTCCCCTTCCCCTGAGC CGAGGCTCCCTGGCTGCTGTGGCCCATGCACAGTCCCTGGTAGAAGCACAGCCCAACGTG GACAAGCTCGTGGAGGACCACCTGGCAGTGCAGTCGCTCATCAGGGCATATCAGATACGA GGGCACCATGTAGCACAGCTGGACCCCCTGGGGATTTTGGATGCTGATCTGGACTCCTCC GTGCCCGCTGACATTATCTCATCCACAGACAAACTTGGGTTCTATGGCCTGGATGAGTCT GACCTCGACAAGGTCTTCCACTTGCCCACCACCACTTTCATCGGGGGACAGGAATCAGCA CTTCCTCTGCGGGAGATCATCCGTCGGCTGGAGATGGCCTACTGCCAGCATATTGGGGTG GAGTTCATGTTCATCAATGACCTGGAGCAGTGCCAGTGGATCCGGCAGAAGTTTGAGACC CCTGGGATCATGCAGTTCACAAATGAGGAGAAACGGACCCTGCTGGCCAGGCTTGTGCGG TCCACCAGGTTTGAGGAGTTCCTACAGCGGAAGTGGTCCTCTGAGAAGCGCTTTGGTCTA GAAGGCTGCGAGGTACTGATCCCTGCCCTCAAGACCATCATTGACAAGTCTAGTGAGAAT GGCGTGGACTACGTGATCATGGGCATGCCACACAGAGGGCGGCTGAACGTGCTTGCAAAT GTCATCAGGAAGGAGCTGGAACAGATCTTCTGTCAATTCGATTCAAAGCTGGAGGCAGCT GATGAGGGCTCCGGAGATGTGAAGTACCACCTGGGCATGTATCACCGCAGGATCAATCGT GTCACCGACAGGAACATTACCTTGTCCTTGGTGGCCAACCCTTCCCACCTTGAGGCCGCT GACCCCGTGGTGATGGGCAAGACCAAAGCCGAACAGTTTTACTGTGGCGACACTGAAGGG AAAAAGGTCATGTCCATCCTGTTGCATGGGGATGCTGCATTTGCTGGCCAGGGCATTGTG TACGAGACCTTCCACCTCAGCGACCTGCCATCCTACACAACTCATGGCACCGTGCACGTG GTCGTCAACAACCAGATCGGCTTCACCACCGACCCTCGGATGGCCCGCTCCTCCCCCTAC CCCACTGACGTGGCCCGAGTGGTGAATGCCCCCATTTTCCACGTGAACTCAGATGACCCC GAGGCTGTCATGTACGTGTGCAAAGTGGCGGCCGAGTGGAGGAGCACCTTCCACAAGGAC GTGGTTGTCGATTTGGTGTGTTACCGGCGCAACGGCCACAACGAGATGGATGAGCCCATG TTCACGCAGCCGCTCATGTACAAGCAGATCCGCAAGCAGAAGCCTGTGTTACAGAAGTAC GCTGAGCTGCTGGTGTCGCAGGGTGTGGTCAACCAGCCTGAGTATGAGGAGGAAATTTCC AAGTATGATAAGATCTGTGAGGAAGCTTTTGCCAGATCTAAAGATGAGAAGATCTTGCAC ATTAAGCACTGGCTGGACTCTCCCTGGCCTGGCTTCTTCACCCTGGACGGGCAGCCCAGG AGCATGTCCTGCCCCTCCACGGGTCTGACGGAGGATATTCTGACACACATCGGGAATGTG GCTAGTTCTGTGCCTGTGGAAAACTTTACTATTCATGGAGGGCTGAGCCGGATCTTGAAG ACTCGTGGGGAAATGGTGAAGAACCGGACTGTGGACTGGGCTCTAGCGGAGTACATGGCG TTTGGCTCGCTCCTGAAGGAGGGCATCCACATTCGGCTGAGCGGCCAGGACGTGGAGCGG GGCACATTCAGCCACCGCCACCATGTGCTCCATGACCAGAATGTGGACAAGAGAACCTGC ATCCCCATGAACCATCTCTGGCCCAATCAGGCCCCCTATACTGTGTGCAACAGCTCACTG TCTGAGTACGGCGTGCTGGGCTTTGAGCTGGGCTTCGCCATGGCCAGTCCTAATGCCCTG GTCCTCTGGGAAGCCCAATTTGGTGACTTCCACAACACGGCCCAGTGTATCATCGACCAG TTCATCTGCCCGGGACAAGCCAAGTGGGTGCGGCAGAATGGCATCGTGTTGCTGCTGCCC CATGGCATGGAGGGCATGGGTCCAGAACATTCCTCCGCCCGCCCAGAGCGGTTCTTGCAG ATGTGCAACGATGACCCAGATGTCCTGCCAGACCTTAAAGAAGCCAACTTCGACATCAAT CAGCTATATGACTGCAATTGGGTTGTTGTCAACTGCTCCACTCCTGGCAACTTCTTCCAC GTGCTACGACGCCAGATCCTGCTGCCATTCCGGAAGCCGTTAATTATCTTCACCCCCAAA TCCCTGTTGCGCCACCCCGAGGCCAGATCCAGCTTTGATGAGATGCTTCCAGGAACCCAC TTCCAGCGGGTGATCCCAGAAGATGGCCCTGCAGCTCAGAACCCAGAAAATGTCAAAAGG CTTCTCTTCTGCACCGGCAAAGTGTATTATGACCTCACCCGGGAGCGCAAAGCACGCGAC ATGGTGGGGCAGGTGGCCATCACAAGGATTGAGCAGCTGTCGCCATTCCCCTTTGACCTC CTGCTGAAGGAGGTGCAGAAGTACCCCAATGCTGAGCTGGCCTGGTGCCAGGAGGAGCAC AAGAACCAAGGCTACTATGACTACGTGAAGCCAAGACTTCGGACCACCATCAGCCGCGCC AAGCCCGTCTGGTATGCCGGCCGGGACCCAGCAGCTGCTCCAGCCACCGGCAACAAGAAG ACCCACCTGACGGAGCTGCAGCGCCTCCTGGACACGGCCTTCGACCTGGACGTCTTCAAG AACTTCTCGTAG Clone variation with respect to NM_002541.3 2973 g=>a >OriGene 5' read for NM_002541 unedited
TGTTCAGNNCATATTTNGTNAATNACGNAACTTCACTTATNNAGGGNNCGGCNNCGCGNA ATTNNCGGCACGAAGGGCTTGNAGCCGGNANAAACAGGCAGTTGTGAAAAAACTTCAGGA CAAAAATGTTTCATTTAAGGACTTGTGCTGCTAAGTTGAGGCCATTGACGGCTTCCCAGA CTGTTAAGACATTTTCACAAAACAGACCAGCAGCAGCTAGGACATTTCAACAGATTCGGT GCTATTCTGCACCTGTTGCTGCTGAGCCCTTTCTCAGTGGGACTAGTTCGAACTATGTGG AGGAGATGTACTGTGCTTGGCTGGAAAACCCCAAAAGTGTACATAAGTCATGGGACATTT TTTTTCGCAACACGAATGCCGGAGCCCCACCGGGCACTGCCTACCAGAGTCCCCTTCCCC TGAGCCGAGGCTCCCTGGCTGCTGTGGCCCATGCACAGTCCCTGGTAGAAGCACAGCCCA ACGTGGACAAGCTCGTGGAGGACCACCTGGCAGTGCAGTCGCTCATCAGGGCATATCAGA TACGAGGGCACCATGTAGCACAGCTGGACCCCCTGNGGATTTTGGATGCTGATCTGGACT CCTCCGTGCCCGCTGACATTATCTCATCCACAGACAAACTTGGGTTCTATGGCCTGGATG AGTCTGACCTCGACAGGTCTTCCACTTGCCCACCACCACTTTCATCGGNGGACAGGAATC AGCACTTNCTCTGCGGGAGATCATCCGTCGGCTGGAGATGGCCTACTGCCAGCATATTGG GGTGGAGTTCATGTTCATCAATGACCTGNAGCAGTGCCAGTGGGATCCGCAGAAGTTNGA GACCCCTGGGATCATGCANGTCACAAATGAGGAGAAACGGACCCTGCTGGCCAAGCTTGT GCGGTCCACCCAGTTGAGGAGTTCCTACAACGGAAGTGTCCTCTGAGAACCGCTTTGTCT AAAG >OriGene 3' read for NM_002541 unedited
TACCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TCATGCCCACGGATATAACTTAGTTTATGGGTCAAGCCAATGCAATGCAAAGTTGTTTCT GTTCCTTTTTTTTTTTTTTTAACCAAAATAAATAAATCAAATCTGTCCCTGTGAAGGTCA AAGTGATAAATGAGGGGCAGCTGGCCCCTTGGCCATGGCCTGGCCCCTCACCCCCAGCCC CTCCTTTCCCTTTTTTGACCTGCTTTGGCACAGCAAAAAAAATGATGCATCAAAAAGTCT CCATTGGGTTAAAGGAAAAAAAAAAATTGGTTGGGGTGGGGAGGGATTCCAAAAAAGGAG GTGGAGGGTTAACAGGACCAAGACAGAGCAGCCAGTGCCCCGGCGGTGGCTACCTGAGCG GGGCTTCCTGGCTACACACAAACTCTGTGGGCTCCAGGTGCTGCCTGGGCCCAGGAGGGG TGGGGTGGGGCATGCTTTGGGCCCCACACACCGCCCTGGAACCCTTCCAAGGAACAGCCA AATAATGGGACACCTGCAAAGACTGAAGCCTGCCCCTTTTTTGTGCCAGTTCAGGGCCAA GGTTTTTTTTCCTGGCCAGCTGCCCCCGGGTAATCCCTCATTTCACGCCCCCGGGTGGGG GCCCCACCCAAAAAACCCTCTGCCCGCCCTGGGTTAGATCCGAACTCCAGGCTCCCCCTT AAAAATTCTAAGGGCTCAGGCTCAAAATGAAACCTTTCCTAGTTCTAAAATCCAGGGACC CTGTGCCTTGGTTGGGGGACAGCCGGAACCCCCCCCAACAGGGCCAATTTCCAATTCCAA ATGGGTGAAACTGGTGGGGAGGGTTTTTTNCANATACTANACCTCCCCACAGAAATTCCT TAGAGGTTTATTTTGCCCTTCGGGCTGCCCCAGCGNCTGGAGAAAATGTNCAGATTATAT AAACCCGGNCCCTGGTGCCCCGGGGGAATCAAATATTGTGGGGGTGGACCAGTCCCTCCC TTTCGCGCTGAGGGGGTTTCTCCCCCTGTAGACGTCGTGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002541 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002541.2, NP_002532.2 |
| RefSeq Size | 4257 bp |
| RefSeq ORF | 3072 bp |
| Locus ID | 4967 |
| UniProt ID | Q02218 |
| Domains | E1_dehydrog, transket_pyr |
| Protein Families | Druggable Genome |
| Protein Pathways | Citrate cycle (TCA cycle), Lysine degradation, Metabolic pathways, Tryptophan metabolism |
| Gene Summary | This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200446 | OGDH (Myc-DDK-tagged)-Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 7,128.00 |
|
| RC200446L1 | Lenti ORF clone of Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 9,528.00 |
|
| RC200446L2 | Lenti ORF clone of Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 10,640.00 |
|
| RC200446L3 | Lenti ORF clone of Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 10,640.00 |
|
| RC200446L4 | Lenti ORF clone of Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 9,528.00 |
|
| RG200446 | OGDH (tGFP-tagged) - Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 9,600.00 |
|
| SC324589 | OGDH (untagged)-Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 7,128.00 |
