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BACE2 (NM_138992) Human Untagged Clone
CAT＃: SC127678
BACE2 (untagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b
CNY 3,656.00
CNY 6,460.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127678 sequence for NM_138992 edited (data generated by NextGen Sequencing)
ATGGGCGCACTGGCCCGGGCGCTGCTGCTGCCTCTGCTGGCCCAGTGGCTCCTGCGCGCC GCCCCGGAGCTGGCCCCCGCGCCCTTCACGCTGCCCCTCCGGGTGGCCGCGGCCACGAAC CGCGTAGTTGCGCCCACCCCGGGACCCGGGACCCCTGCCGAGCGCCACGCCGACGGCTTG GCGCTCGCCCTGGAGCCTGCCCTGGCGTCCCCCGCGGGCGCCGCCAACTTCTTGGCCATG GTAGACAACCTGCAGGGGGACTCTGGCCGCGGCTACTACCTGGAGATGCTGATCGGGACC CCCCCGCAGAAGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGA ACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCC AAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAA GACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATT TTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCT TATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACA CAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCT GGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAA GGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAA TTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCC ATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTG GAAGCTGTGGCCCGCGCATCTCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCC CAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAATCTCCATC TACCTGAGAGAYGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTG CAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAG Clone variation with respect to NM_138992.1 1092 c=>y >OriGene 5' read for NM_138992 unedited
GTAACACGACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGGCCCCGCGCGCCGGCCG AGTCGCTGAGCCGCGGCTGCCGGACGGGACGGGACCGGCTAGGCTGGGCGCGCCCCCCGG GCCCCGCCGTGGGCATGGGCGCACTGGCCCGGGCGCTGCTGCTGCCTCTGCTGGCCCAGT GGCTCCTGCGCGCCGCCCCGGAGCTGGCCCCCGCGCCCTTCACGCTGCCCCTCCGGGTGG CCGCGGCCACGAACCGCGTAGTTGCGCCCACCCCGGGACCCGGGACCCCTGCCGAGCGCC ACGCCGACGGCTTGGCGCTCGCCCTGGAGCCTGCCCTGGCGTCCCCCGCGGGCGCCGCCA ACTTCTTGGCCATGGTAGACAACCTGCAGGGGGACTCTGGCCGCGGCTACTACCTGGAGA TGCTGATCGGGACCCCCCCGCAGAAGCTACAGATTCTCGTTGACACTGGAAGCAGTAACT TTGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTA GCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGG GCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCA ACATTGCCACTATTTTTGAATCAGAGAATTTCTTTNTGCCTGGGATTAAATGGAATGGAA TACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCANAGTCTCTGGAGACCTTCTTCG ACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCC GCTTGCCCGTTGCTGGATCTGGGACCCACGGNAGTAGTCTGTCTTGGNTGGAANTGAACA AGTTGTATAAAGAGACATCTGTATACCCT >OriGene 3' read for NM_138992 unedited
GGCCGCATTTTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTGGAAGTAGGGAGGATTTGA AAGCTTGAAAATCAAGAATCAAAAGACAGTGAATCTAGAAGGCATCTGGGAGCAGAACAG AGATTGAAGACGGGTGGGCACAGGAGAAAGCGCCACCATCGATCCCGGCTGCTGCCCTGG AAATGTGATTTTCTTAATAGCTGAGTTCATGGTTGCTTGAGGTCAGGCCTGGCTATTCAT TTCCAGCGATGTCTGACCAGAGAGGACTCATCATTGACGACCTCAGGGTCACGGGGGCGA CGCTGACACCGGAACGGCAGCAGCAGCAGGACGATTAAGACAAGGAGGATGGCTCCACAG ACGCTCATGAGCGCATAGGACACAATCCACAAAATGGGCTCGCTCAAAGACTGAGCGGGG ACACAGTTGCTGGCTACATCCTCTGTTGAGAAAGGCCCGGAAATTTCAGACACTGCAGCA CCTGCAATTTCTGCACAGGGGCTCGCTGCGAAGCCCACCCTCTTCTGGGCTCTGTCGAAG ATGACGTAGAAGCCCTCCATCACCGTGGCACCAATCACCAGCGCATTTGTGGATGGGGAA ATGCCGAATCGGTAACATTCATAATTCAGGCCGGCCCCCATCATGGGCTGAATGTAAAGC TGAGGCAGGATTGTGATACGGAATGACCTGCTGGAGTTCTCGTCTCTCAGGTAGATGGAG ATTCTAGGGAAGTAAGACCAAGGTGTTCCGAATTCGTCCAGCACGCCAGCTGGGACCCAG TCCAGAAACCATCAGNAGAATTCTGGGAATCAGAGATGCGCGGNCCCACAGCTTTCACCA CCGCATCAAACACCTTCTGGGGCGCAGCCGCACAACGTGGTGGCACTGTCCACNATGCCC TGCTTGCGNATACTTTTTGCAGCCAGATTAAGCTTTGGCCTCCATTCCAATTTCAGATTC TTATTGTAGACN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_138992 |
| Insert Size | 1920 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_138992.1, NP_620477.1 |
| RefSeq Size | 2824 bp |
| RefSeq ORF | 1191 bp |
| Locus ID | 25825 |
| UniProt ID | Q9Y5Z0 |
| Domains | asp |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Protein Pathways | Alzheimer's disease |
| Gene Summary | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (b) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant a. The encoded isoform (B) is shorter and has a distinct C-terminus, compared to isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213667 | BACE2 (Myc-DDK-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b |
CNY 3,656.00 |
|
| RC213667L1 | Lenti-ORF clone of BACE2 (Myc-DDK-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b |
CNY 6,056.00 |
|
| RC213667L2 | Lenti-ORF clone of BACE2 (mGFP-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b |
CNY 5,890.00 |
|
| RC213667L3 | Lenti-ORF clone of BACE2 (Myc-DDK-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b |
CNY 5,890.00 |
|
| RC213667L4 | Lenti-ORF clone of BACE2 (mGFP-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b |
CNY 5,890.00 |
|
| RG213667 | BACE2 (tGFP-tagged) - Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b |
CNY 4,370.00 |
