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MX2 (NM_002463) Human Untagged Clone
CAT＃: SC127459
MX2 (untagged)-Human myxovirus (influenza virus) resistance 2 (mouse) (MX2)
CNY 7,864.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MXB |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127459 sequence for NM_002463 edited (data generated by NextGen Sequencing)
ATGTCTAAGGCCCACAAGCCTTGGCCCTACCGGAGGAGAAGTCAATTTTCTTCTCGAAAA TACCTGAAAAAAGAAATGAATTCCTTCCAGCAACAGCCACCGCCATTCGGCACAGTGCCA CCACAAATGATGTTTCCTCCAAACTGGCAGGGGGCAGAGAAGGACGCTGCTTTCCTCGCC AAGGACTTCAACTTTCTCACTTTGAACAATCAGCCACCACCAGGAAACAGGAGCCAACCA AGGGCAATGGGGCCCGAGAACAACCTGTACAGCCAGTACGAGCAGAAGGTGCGCCCCTGC ATTGACCTCATCGACTCCCTGCGGGCTCTGGGTGTGGAGCAGGACCTGGCCCTGCCAGCC ATCGCCGTCATCGGGGACCAGAGCTCGGGCAAGAGCTCTGTGCTGGAGGCACTGTCAGGA GTCGCGCTTCCCAGAGGCAGCGGAATCGTAACCAGGTGTCCGCTGGTGCTGAAACTGAAA AAGCAGCCCTGTGAGGCATGGGCCGGAAGGATCAGCTACCGGAACACCGAGCTAGAGCTT CAGGACCCTGGCCAGGTGGAGAAAGAGATACACAAAGCCCAGAACGTCATGGCCGGGAAT GGCCGGGGCATCAGCCATGAGCTCATCAGCCTGGAGATCACCTCCCCTGAGGTTCCAGAC TTGACCATCATTGACCTTCCCGGCATCACCAGGGTGGCTGTGGACAACCAGCCCCGAGAC ATCGGACTGCAGATCAAGGCTCTCATCAAGAAGTACATCCAGAGGCAGCAGACGATCAAC TTGGTGGTGGTTCCCTGTAACGTGGACATTGCCACCACGGAGGCGCTGAGCATGGCCCAT GAGGTGGACCCGGAAGGGGACAGGACCATCGGTATCCTGACCAAACCAGATCTAATGGAC AGGGGCACTGAGAAAAGCGTCATGAATGTGGTGCGGAACCTCACGTACCCCCTCAAGAAG GGCTACATGATTGTGAAGTGCCGGGGCCAGCAGGAGATCACAAACAGGCTGAGCTTGGCA GAGGCAACCAAGAAAGAAATTACATTCTTTCAAACACATCCATATTTCAGAGTTCTCCTG GAGGAGGGGTCAGCCACGGTTCCCCGACTGGCAGAAAGACTTACCACTGAACTCATCATG CATATCCAAAAATCGCTCCCGTTGTTAGAAGGACAAATAAGGGAGAGCCACCAGAAGGCG ACCGAGGAGCTGCGGCGTTGCGGGGCTGACATCCCCAGCCAGGAGGCCGACAAGATGTTC TTTCTAATTGAGAAAATCAAGATGTTTAATCAGGACATCGAAAAGTTAGTAGAAGGAGAA GAAGTTGTAAGGGAGAATGAGACCCGTTTATACAACAAAATCAGAGAGGATTTTAAAAAC TGGGTAGGCATACTTGCAACTAATACCCAAAAAGTTAAAAATATTATCCACGAAGAAGTT GAAAAATATGAAAAGCAGTATCGAGGCAAGGAGCTTCTGGGATTTGTCAACTACAAGACA TTTGAGATCATCGTGCATCAGTACATCCAGCAGCTGGTGGAGCCCGCCCTTAGCATGCTC CAGAAAGCCATGGAAATTATCCAGCAAGCTTTCATTAACGTGGCCAAAAAACATTTTGGC GAATTTTTCAACCTTAACCAAACTGTTCAGAGCACGATTGAAGACATAAAAGTGAAACAC ACAGCAAAGGCAGAAAACATGATCCAACTTCAGTTCAGAATGGAGCAGATGGTTTTTTGT CAAGATCAGATTTACAGTGTTGTTCTGAAGAAAGTCCGAGAAGAGATTTTTAACCCTCTG GGGACGCCTTCACAGAATATGAAGTTGAACTCTCATTTTCCCAGTAATGAGTCTTCGGTT TCCTCCTTTACTGAAATAGGCATCCACCTGAATGCCTACTTCTTGGAAACCAGCAAACGT CTCGCCAACCAGATCCCATTTATAATTCAGTATTTTATGCTCCGAGAGAATGGTGACTCC TTGCAGAAAGCCATGATGCAGATACTACAGGAAAAAAATCGCTATTCCTGGCTGCTTCAA GAGCAGAGTGAGACCGCTACCAAGAGAAGAATCCTTAAGGAGAGAATTTACCGGCTCACT CAGGCGCGACACGCACTCTGTCAATTCTCCAGCAAAGAGATCCACTGA Clone variation with respect to NM_002463.1 661 c=>t >OriGene 5' read for NM_002463 unedited
TTTGTATACGACTCACTATAGGCGGCCGCGAATTCGGCACGAGGGGAAGATCGGAGGTGC CAAGTAGCAGAGAAAGCATCCCCCAGCTCTGACAGGGAGACAGCACATGTCTAAGGCCCA CAAGCCTTGGCCCTACCGGAGGAGAAGTCAATTTTCTTCTCGAAAATACCTGAAAAAAGA AATGAATTCCTTCCAGCAACAGCCACCGCCATTCGGCACAGTGCCACCACAAATGATGTT TCCTCCAAACTGGCAGGGGGCAGAGAAGGACGCTGCTTTCCTCGCCAAGGACTTCAACTT TCTCACTTTGAACAATCAGCCACCACCAGGAAACAGGAGCCAACCAAGGGCAATGGGGCC CGAGAACAACCTGTACAGCCAGTACGAGCAGAAGGTGCGCCCCTGCATTGACCTCATCGA CTCCCTGCGGGCTCTGGGTGTGGAGCAGGACCTGGCCCTGCCAGCCATCGCCGTCATCGG GGACCAGAGCTCGGGCAAGAGCTCTGTGCTGGAGGCACTGTCAGGAGTCGCGCTTCCCAG AGGCAGCGGAATCGTAACCAGGTGTCCGCTGGTGCTGAAACTGANAAAGCAGCCCTGTGA GGCATGGGCCGGAAGGATCAGCTACCGGAACACCGAGCTAGAGCTTCAGGACCCTGGCCA GGTGGAGAAAGAGAACACAAAGCCCAAAACGTCATGGCCCGGGAATGGCCGGGGCATCAN CCATGAGCTCATCAGCCTGGGAGATCACCTNCCCCTGAGGGTCCCAGACTTGACCATCAT TTGACCTTCCCGGCATCACCAGGGTGGGCTGTTGGAACACCAGCCCCCGAGACTTCGGAC TGGCAGATCAAGGCTCTCATCAGGAAGTACATCCAGAGGCAGCAGACGATCAACTTGGGG GGGGGGGNNTCCTGTTACGTTGGACATGGCA >OriGene 3' read for NM_002463 unedited
TGTGGCTTTTCTAAGCTTTACATGCTGCAGTGCTGTGCAGGGAGATGGACATACAAAATA AGAATTTGACCCAGACCTTCCCCCTCTGGGGTCTCATAATCTTGTAGGGGGAAGGGAATA CAAATACAAATTAGCGAAGAATGATAGCAGTATCTTAGGACACTGTAACTGTGTGCTACG GGACCCAAGGACTGGAGAGCCATCCCTTCGTGAAGGTCAGGGAAGAGCTGGGTGGTGGAG AGAGCTGAGCCTGTGTGGACCCCTGATGCATGCTCTGATGCTGAGGGAGTACAGTAGAGA TGGACACTGATAGTGACAGAAGAGTTTGGCCCCAAAGCAGAAGCGGCATCCTGCACCGAC TCCCCTTAGAATGAATGAGTACGCACAAGAAAACAACCACAGGCATCGCCGCCCTTCAGT GGATCTCTTTGCTGGAGAATTGACAGAGTGCGTGTCGCGCCTGAGTGAGCCGGTAAATTC TCTTCTTAAGGATTCTTCTTTTGGTAGCGGTCTCACTCTGCTCTTGAAGCAGCCAGGAAT AGCGATTTTTTTCCTGGTAGATCTGCATCATGGCTTTCTGCAAGGAGTCACCATTCTCTC GGAGCATAAAATACTGAATTATAAATGGGATCTGGTTGGCGAGACGGTTGTTGGTTTCCA AGAAGTAGGCATTCACGTGGATGCCTATTTCATTAAAGGAGGAAACCGACCACTCTTACT TGGAATATGAGCAGTTAACTTATATTCTGTGAAGGCGTTCCCACAGGCTAAAGACTTTTT CTCCGACTTTCTTCCGAACAACCTTGTAAAGTGGATTTGACAAAAATCATCTGCTCATTC CGATCGTAACTGGTCCATGTTTTTGCCCTTGCGCGGAGTGAACGTTTAGGTATCCATCGG CCCTTCACAATTGGTACGCTTTATAATCCGCCTTAGTTCCCGCCCCCTATTAAACTTGTA CCAACCCTCGCCCCCGGAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002463 |
| Insert Size | 2800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002463.1, NP_002454.1 |
| RefSeq Size | 2961 bp |
| RefSeq ORF | 2148 bp |
| Locus ID | 4600 |
| UniProt ID | P20592 |
| Domains | dynamin_2, dynamin, GED |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MX2 is a novel regulator of cell cycle in melanoma cells
,Juraleviciute, M;Pozniak, J;Nsengimana, J;Harland, M;Randerson-Moor, J;Wernhoff, P;Bassarova, A;Øy, GF;Trøen, G;Flørenes, VA;Bishop, DT;Herlyn, M;Newton-Bishop, J;Slipicevic, A;,
Pigment Cell Melanoma Res
,PubMed ID 31660681
[MX2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206437 | MX2 (Myc-DDK-tagged)-Human myxovirus (influenza virus) resistance 2 (mouse) (MX2) |
CNY 7,856.00 |
|
| RC206437L1 | Lenti ORF clone of Human myxovirus (influenza virus) resistance 2 (mouse) (MX2), Myc-DDK-tagged |
CNY 10,256.00 |
|
| RC206437L2 | Lenti ORF clone of Human myxovirus (influenza virus) resistance 2 (mouse) (MX2), mGFP tagged |
CNY 5,890.00 |
|
| RC206437L3 | Lenti ORF clone of Human myxovirus (influenza virus) resistance 2 (mouse) (MX2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206437L4 | Lenti ORF clone of Human myxovirus (influenza virus) resistance 2 (mouse) (MX2), mGFP tagged |
CNY 10,256.00 |
|
| RG206437 | MX2 (tGFP-tagged) - Human myxovirus (influenza virus) resistance 2 (mouse) (MX2) |
CNY 4,370.00 |
