HPS3 (NM_032383) Human Untagged Clone
CAT#: SC127283
HPS3 (untagged)-Human Hermansky-Pudlak syndrome 3 (HPS3)
CNY 7,000.00
Cited in 1 publication. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | BLOC2S1; SUTAL |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC127283 sequence for NM_032383 edited (data generated by NextGen Sequencing)
ATGGTGCAGCTGTACAACCTGCACCCGTTCGGGTCGCAGCAGGTGGTGCCCTGCAAGCTG GAGCCGGACCGGTTCTGTGGCGGGGGGCGTGACGCGCTTTTCGTGGCGGCGGGCTGCAAG GTGGAGGCGTTCGCGGTGGCCGGCCAGGAGCTGTGCCAGCCGCGGTGCGCCTTCTCCACG CTGGGCCGGGTGTTGCGCCTGGCCTACAGCGAGGCTGGAGATTATTTGGTAGCAATTGAA GAGAAAAACAAAGCTACATTTCTACGTGCTTATGTGAACTGGAGAAATAAAAGGACTGAA AACTCTCGTGTGTGTATCCGAATGATTGGGCATAATGTGGAGGGACCATTCAGCAAAGCC TTCAGAGACCAGATGTACATTATTGAAATGCCGCTTTCGGAGGCCCCCTTGTGCATTTCC TGTTGCCCTGTGAAAGGAGACCTTCTCGTTGGCTGCACAAATAAATTAGTCTTATTTAGT TTGAAGTACCAGATCATTAATGAGGAATTCTCACTATTGGACTTTGAACGTTCTTTAATT ATACACATAGATAATATCACTCCTGTTGAGGTTTCTTTTTGTGTTGGATATGTTGCTGTC ATGTCAGACTTAGAAGTCTTAATCGTAAAACTGGAGTCAGGCCCTAAAAATGGAGAGAGA GTTCACCACCATCCACATAAGACCAACAATCGAATAAGACGGACAGAAGAAGGCATCAGT AATGAAATTTCACAGCTTGAGTCAGATGATTTTGTCATCTGCCAGAAGCCCCTGGAACTT CTTGGTGAAAAAAGTGAACAGTCTGGATTATCTGTTACACTGGAGTCTACGGGATTAGCT GATGAAAAAAGAAAATATTCCCACTTTCAGCACCTGCTCTATAGACGTTTTGCTCCTGAT ATTTCGTCCTATGTCTTGTCTGATGACATCAAGCTACATTCCCTCCAGCTGCTACCCATT TACCAGACCGGTTCTCTTACGTCTGATGGAAAAAATTTGTCTCAGGAAAAAGAATTGCTG AGTCTCTTTTGCTTTTTCTCCTTACCTCATGTGGGCTATCTCTACATGGTTGTCAAATCT GTTGAATTGATGTCAGTCTACCAGTATCCTGAAAAGTCTCAGCAGGCAGTACTCACGCCA CAATTTTTGCACGTCATTACAAGTAACAACCTGCAGTGTTTCACTGTGCGGTGCAGTGCG GCGGCAGCTCGTGAGGAGGACCCGTACATGGACACCACCCTGAAGGCTTGCCCACCTGTC AGTATGGATGTCTGTGCTTTAAGAATACAGCTTTTCATAGGCTTGAAAGCCATCTGTCAC TTTAAAAACCACATCATACTTTTGACTAAAGCAGAACCTGAAGCCATTCCAGAGAGAAGA CAGTCACCCAAGAGGCTTCTTTCGAGAAAAGATACCAGTGTTAAAATCAAAATACCTCCT GTAGCTGAGGCTGGGTGGAATTTGTATATTGTGAATACGATCTCACCAGTGCAGCTGTAC AAAGAGATGGTAGACTATAGCAATACCTATAAGACTGTCAAAACCCAGAGCTGCATTCAC CTTCTCAGTGAGGCTCATCTGTTAGTGCGAGCTGCCCTGATGGATGCCAGTCAGCTGGAA CCTGGAGAGAAGGCAGAGCTTTTGGAAGCATTTAAGGAAAGCTGTGGGCACCTTGGGGAC TGTTACAGCAGGCTTGACTCCCAGCATTCTCATCTCACCTTGCCATACTATAAGATGTCT GGTTTGTCTATGGCTGAAGTTCTGGCCCGCACGGACTGGACAGTAGAGGATGGATTACAG AAATACGAGAGAGGATTAATCTTTTACATTAATCATTCACTTTATGAAAACCTGGATGAA GAATTAAATGAAGAATTAGCAGCAAAAGTGGTTCAGATGTTTTATGTGGCTGAGCCAAAG CAAGTGCCCCATATTCTCTGTAGTCCTTCTATGAAGAATATTAATCCTTTAACTGCCATG AGCTATCTAAGGAAGCTGGATACTTCTGGGTTTTCATCGATCTTAGTGACATTGACCAAG GCAGCAGTGGCTCTGAAAATGGGAGATCTTGACATGCACAGAAATGAAATGAAAAGCCAT TCAGAGATGAAGTTGGTATGTGGCTTCATTCTGGAACCTCGGCTGTTGATTCAACAGAGA AAGGGACAGATTGTTCCAACCGAGCTTGCACTTCACTTGAAGGAAACTCAGCCTGGATTG CTTGTGGCTTCAGTTCTGGGCTTGCAGAAGAACAACAAAATTGGAATTGAAGAAGCAGAT TCCTTTTTTAAGGTGCTTTGTGCTAAGGATGAAGATACAATTCCTCAGCTCTTGGTAGAC TTTTGGGAAGCTCAGCTAGTGGCATGTCTCCCAGATGTGGTACTTCAGGAACTCTTTTTC AAACTCACATCACAGTACATCTGGAGATTGTCTAAGAGGCAGCCTCCTGACACCACACCA TTGCGAACATCGGAGGATCTGATAAATGCCTGTAGTCATTATGGCTTAATTTATCCATGG GTTCACGTCGTAATATCATCTGATTCTTTAGCTGATAAAAATTATACAGAAGATCTTTCA AAATTACAGTCTCTTATATGTGGTCCTTCATTTGACATAGCTTCCATTATTCCGTTCTTG GAGCCACTTTCAGAAGACACTATTGCCGGCCTCAGTGTCCATGTTCTGTGTCGTACACGC TTGAAAGAGTATGAACAGTGCATAGACATACTGTTAGAGAGATGCCCGGAGGCAGTCATT CCATATGCTAATCATGAACTGAAAGAAGAGAACCGGACTCTGTGGTGGAAAAAACTGTTG CCTGAACTTTGTCAGAGAATAAAATGTGGTGGAGAGAAGTATCAACTCTACCTGTCATCA TTAAAAGAAACATTGTCAATTGTTGCTGTGGAACTAGAACTGAAGGATTTCATGAATGTT CTCCCAGAAGATGGTACTGCAACATTTTTCTTGCCATATCTTCTCTATTGCAGTCGAAAG AAACCATTGACTTAA Clone variation with respect to NM_032383.3 981 a=>g >OriGene 5' read for NM_032383 unedited
AGTATTTTGTAATACGAACTCACTATAGGGCGGCCGCGATTCGGCACGAGGTCCCGCCGG ACGTCGGGATGGTGCAGCTGTACAACCTGCACCCGTTCGGGTCGCAGCAGGTGGTGCCCT GCAAGCTGGAGCCGGACCGGTTCTGTGGCGGGGGGCGTGACGCGCTTTTCGTGGCGGCGG GCTGCAAGGTGGAGGCGTTCGCGGTGGCCGGCCAGGAGCTGTGCCAGCCGCGGTGCGCCT TCTCCACGCTGGGCCGGGTGTTGCGCCTGGCCTACAGCGAGGCTGGAGATTATTTGGTAG CAATTGAAGAGAAAAACAAAGCTACATTTCTACGTGCTTATGTGAACTGGAGAAATAAAA GGACTGAAAACTCTCGTGTGTGTATCCGAATGATTGGGCATAATGTGGAGGGACCATTCA GCAAAGCCTTCAGAGACCAGATGTACATTATTGAAATGCCGCTTTCGGAGGCCCCCTTGT GCATTTCCTGTTGCCCTGTGAAAGGAGACCTTCTCGTTGGCTGCACAAATAAATTAGTCT TATTTAGTTTGAAGTACCAGATCATTAATGAGGAATTCTCACTATTGGACTNTGAACGTT CTTTAATTATACACATAGATAATATCACTCCTGGTTGAGGTTTCTTTTTTGTGTTGGATA TGGTTGCTGTCATGTCAACTTTTAAAAGTCTTAATCGTAAAACTGGNNAGTCNGGCCCCT AAAATGGANAANAGAGTTNCACCACCATCCACATTAGACCAANCATCGAANTAGACGACA GGAGAAGGCATCAGTAATGAAATTTCACAGCTGAGTCAGATGGATTTGGTCATCTGCCAA AAGCCCCTGNACTTTCCTGGTGGAAAAAAGTGACAGTNCTGGATTATCTGTTACC >OriGene 3' read for NM_032383 unedited
NGGGGGTATTAGCTTGNACCGCGGCCCGCTTTCTANATCGAGTTTTTTTTTTTTTTTTTT GTGAATACAATGATGTATTTCTTTATTTTCACATACACTCTAGCTAAAAGAGCAAGAGTA CACATCAACAAAATGGAAACAAGGCTTTGGCTGAAAAAAACATGCATTTGACAAATCATG TTAATAGCTAGACAAGAAGAAAGTTAGCTTTGTAAACTTCTACTTCATTTGATTCAGAGA AACAGAGCATGAGTTTTCTTAAAAGTAACAAGAAAAGGAACAAAAAAAATGAGGTTTGAA ATCTTTTACCATGGCAAAACATTAACATCTTTCTCAAAAACATAGAGAAATCTGGAAAAA TCAAGAAGATAAAATTCTGGACCAGTTAGTGACATTCTTTCAAGCATACTTGTAAAATGT TTCCTTAAAGTGTTCTTGGGATGAAAATGATTGTCATGTCTCCAACAACAGTGAACTGAT GTTGTTCCTTGGAATAAAAGTCAATCCCCACCTTAAAAAATGTATGGCTTCTTTGAGGAA TTCTTATGTCTTAAAGACTTTTTACATTCTAGACAATTAAATTGATTGAGGTCATAAATT AAGAAGTGAATAGTTACCACTACACGGTAAGGTAAGCAGCCTGAAAGCATTTGTATCATA TATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNTGTGTGAAATATAAAAATAAAAAAC TCCTCTACTTGTACTTTGGCATTCAATTTTTAGAAATTCAGTCTCAAATGCCATTATGGT ATTTTTCAAATGATACCTTTAAGTCAATGGTTTCTTTCGACTGCCATAGAGGAGATATGG CAAGGAAAAATGTGCAGTACCATCTTCTGGGAGGAACATCATGAAAATCTTCAGTT |
Restriction Sites | NotI-NotI |
ACCN | NM_032383 |
Insert Size | 4000 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_032383.3, NP_115759.2 |
RefSeq Size | 4451 bp |
RefSeq ORF | 3015 bp |
Locus ID | 84343 |
UniProt ID | Q969F9 |
Gene Summary | This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. [provided by RefSeq, Apr 2015] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery
,Dennis, MK;Mantegazza, AR;Snir, OL;Tenza, D;Acosta-Ruiz, A;Delevoye, C;Zorger, R;Sitaram, A;de Jesus-Rojas, W;Ravichandran, K;Rux, J;Sviderskaya, EV;Bennett, DC;Raposo, G;Marks, MS;Setty, SR;,
J. Cell Biol.
,PubMed ID 26008744
[HPS3]
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Other Versions
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RC204569 | HPS3 (Myc-DDK-tagged)-Human Hermansky-Pudlak syndrome 3 (HPS3) |
CNY 6,992.00 |
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RC204569L3 | Lenti ORF clone of Human Hermansky-Pudlak syndrome 3 (HPS3), Myc-DDK-tagged |
CNY 10,450.00 |
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RC204569L4 | Lenti ORF clone of Human Hermansky-Pudlak syndrome 3 (HPS3), mGFP tagged |
CNY 10,450.00 |
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RG204569 | HPS3 (tGFP-tagged) - Human Hermansky-Pudlak syndrome 3 (HPS3) |
CNY 8,592.00 |