United States
Germany
Japan
United Kingdom
China
NR1D1 (NM_021724) Human Untagged Clone
CAT＃: SC127002
NR1D1 (untagged)-Human nuclear receptor subfamily 1, group D, member 1 (NR1D1)
CNY 6,864.00
| Cited in 1 publication. |
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ear-1; EAR1; hRev; REVERBA; REVERBalpha; THRA1; THRAL |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127002 sequence for NM_021724 edited (data generated by NextGen Sequencing)
ATGACGACCCTGGACTCCAACAACAACACAGGTGGCGTCATCACCTACATTGGCTCCAGT GGCTCCTCCCCAAGCCGCACCAGCCCTGAATCCCTCTATAGTGACAACTCCAATGGCAGC TTCCAGTCCCTGACCCAAGGCTGTCCCACCTACTTCCCACCATCCCCCACTGGCTCCCTC ACCCAAGACCCGGCTCGCTCCTTTGGGAGCATTCCACCCAGCCTGAGTGATGACGGCTCC CCTTCTTCCTCATCTTCCTCGTCGTCATCCTCCTCCTCCTTCTATAATGGGAGCCCCCCT GGGAGTCTACAAGTGGCCATGGAGGACAGCAGCCGAGTGTCCCCCAGCAAGAGCACCAGC AACATCACCAAGCTGAATGGCATGGTGTTACTGTGTAAAGTGTGTGGGGACGTTGCCTCG GGCTTCCACTACGGTGTGCACGCCTGCGAGGGCTGCAAGGGCTTTTTCCGTCGGAGCATC CAGCAGAACATCCAGTACAAAAGGTGTCTGAAGAATGAGAATTGCTCCATCGTCCGCATC AATCGCAACCGCTGCCAGCAATGTCGCTTCAAGAAGTGTCTCTCTGTGGGCATGTCTCGA GACGCTGTGCGTTTTGGGCGCATCCCCAAACGAGAGAAGCAGCGGATGCTTGCTGAGATG CAGAGTGCCATGAACCTGGCCAACAACCAGTTGAGCAGCCAGTGCCCGCTGGAGACTTCA CCCACCCAGCACCCCACCCCAGGCCCCATGGGCCCCTCGCCACCCCCTGCTCCGGTCCCC TCACCCCTGGTGGGCTTCTCCCAGTTTCCACAACAGCTGACGCCTCCCAGATCCCCAAGC CCTGAGCCCACAGTGGAGGATGTGATATCCCAGGTGGCCCGGGCCCATCGAGAGATCTTC ACCTACGCCCATGACAAGCTGGGCAGCTCACCTGGCAACTTCAATGCCAACCATGCATCA GGTAGCCCTCCAGCCACCACCCCACATCGCTGGGAAAATCAGGGCTGCCCACCTGCCCCC AATGACAACAACACCTTGGCTGCCCAGCGTCATAACGAGGCCCTAAATGGTCTGCGCCAG GCTCCCTCCTCCTACCCTCCCACCTGGCCTCCTGGCCCTGCACACCACAGCTGCCACCAG TCCAACAGCAACGGGCACCGTCTATGCCCCACCCACGTGTATGCAGCCCCAGAAGGCAAG GCACCTGCCAACAGTCCCCGGCAGGGCAACTCAAAGAATGTTCTGCTGGCATGTCCTATG AACATGTACCCGCATGGACGCAGTGGGCGAACGGTGCAGGAGATCTGGGAGGATTTCTCC ATGAGCTTCACGCCCGCTGTGCGGGAGGTGGTAGAGTTTGCCAAACACATCCCGGGCTTC CGTGACCTTTCTCAGCATGACCAAGTCACCCTGCTTAAGGCTGGCACCTTTGAGGTGCTG ATGGTGCGCTTTGCTTCGTTGTTCAACGTGAAGGACCAGACAGTGATGTTCCTAAGCCGC ACCACCTACAGCCTGCAGGAGCTTGGTGCCATGGGCATGGGAGACCTGCTCAGTGCCATG TTCGACTTCAGCGAGAAGCTCAACTCCCTGGCGCTTACCGAGGAGGAGCTGGGCCTCTTC ACCGCGGTGGTGCTTGTCTCTGCAGACCGCTCGGGCATGGAGAATTCCGCTTCGGTGGAG CAGCTCCAGGAGACGCTGCTGCGGGCTCTTCGGGCTCTGGTGCTGAAGAACCGGCCCTTG GAGACTTCCCGCTTCACCAAGCTGCTGCTCAAGCTGCCGGACCTGCGGACCCTGAACAAC ATGCATTCCGAGAAGCTGCTGTCCTTCCGGGTGGACGCCCAGTGA Clone variation with respect to NM_021724.3 >OriGene 5' read for NM_021724 unedited
TTTTGAATCCGACTTTCTATAGGGCGGCCGCGAATTCGGGCACGAGGGAGGCGCTCCCTG GGATCACATGGTACCTGCTCCAGTGCCGCGTGCGGCCCGGGAACCCTGGGCTGCTGGCGC CTGCGCAGAGCCCTCTGTCCCAGGGAAAGGCTCGGGCAAAAGGCGGCTGAGATTGGCAGA GTGAAATATTACTGCCGAGGGAACGTAGCAGGGCACACGTCTCGCCTCTTTGCGACTCGG TGCCCCGTTTCTCCCCATCACCTACTTACTTCCTGGTTGCAACCTCTCTTCCTCTGGGAC TTTTGCACCGGGAGCTCCAGATTCGCTACCCCGCAGCGCTGCGGAGCCGGCAGGCAGAGG CACCCCGTACACTGCAGAGACCCGACCCTCCTTGCTACCTTCTAGCCAGAACTACTGCAG GCTGATTCCCCCTACACACTCTCTCTGCTCTTCCCATGCAAAGCAGAACTCCGTTGCCTC AACGTCCAACCCTTCTGCAGGGCTGCAGTCCGGCCACCCCAAGACCTTGCTGCAGGGTGC TTCGGATCCTGATCGTGAGTCGCGGGGTCCACTCCCCGCCCTTAGCCAGTGCCCAGGGGG CAACAGCGGCGATCGCAACCTCTAGTTTGAGTCAAGGTCCAGTTTGAATGACCGCTCTCA GCTGGTGAAGACATGACGACCCTGGACTCCAACAACAACACAGGTGGCGTCATCACCTAC ATTGGCTCCAGTGGCTCCTCCCCAGCCGCACCAGCCCTGAATCCCTCTATAGTGACAACT CCAATGGCAGCTTCCAGTCCCTGACCCAGGCTGTCCCACTACTTCCACCATCCCCACTGG CTCCTCACCCAGACCCGCTCGTCCTTGGGGACATCCCCCACCTGATGAGACGCTCCCTCT T >OriGene 3' read for NM_021724 unedited
CCCCGCTATTCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAGCTGTGAACTATTGGATTT GAGACAGGAACAGAACACCTCAGAGGGCCAGGGGAGGGTTGTGGGGGAGACATATTGGTT TAAATAGGGGAGGAGGGGAAGTTCGGTGATGGGGGAGGCAGGCTCCCCCCCCCCCTCCCC CTCCTTCTTTTTCCCCCCTCTCCCCCCCCCCCTTTTCCTCCCTTTCCCTCTTATCTTCTC CTCCCTCCTCCTCCCCTCCTCTCCTCCCCCCTCCCCCCCCCCCCCTCTCCTCCTCCCCCT CTTCCTTTCTCTCCTCTTTCCCCTCTTTCTCCCCTCTCCCTCTCCTCCCCCCCCCCCCGT TTTTTTCCTTTTTCTTTTCTTTTTTTTTCTTCCTCTTTCTCCTCCCTCCCCTTCTCCCCT CCTCCTTCTTTCCCTCCCTCCCCCCTCCCCCCCCTTTCTCTTCCCCTCTTCTTTCCCCTC TCCCCCACTCTCCCCCTCTCCCCCCTCTTTCCCTCCCTTACCTCCCTCCTCCCCCCTCCT CTCCCCTTCCTCTCCCTTTCCCCCCTTCCTCCCCCTCTCTCCCCTCCCTCCCTCTCCCCT CCCCTCCCCCCCCTTCTCCTCTCTCCCTTCCCCCCCCCCCTTCCCTTTTTTTCCCCCTCC TCTCCTCCCTCTCTTTTTTCTCCCCCCTCTCCCTTCCTCCCTACTCCTTTTTCTTTCTTT TCCCCTCCTCTCCCCCTCTCTCCTCCCTTCTTCCCTCCCCCCCTCCCCTCNTTTCTTCCT CTCTCTCCCTCCCCTCTCCCTCCCTCTCCTTCTCCTCCCTCTCCCTCTTCCCCTTCTTCT TTGTCCATCCTTCCATCACTTTCTCCCTGACTTCCTTTCTTCCTCATTCCTCTCTCGCCT CTTCCTTCTACCCCCCACTCCTCTCGCTTTTCCGTTTCCTCTCTCTTCTCTCGTCTTGCT CCCCCTCCTCCCCCTTCTCTTTCTCTCTCTCCCTCTCCTCTCTCTCCTTCCCTCTCCCCT CTACTCTCCGTCCTTCCTCCTCTTCTTTTCTCCTCCTTTATTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021724 |
| Insert Size | 2770 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021724.1, NP_068370.1 |
| RefSeq Size | 2768 bp |
| RefSeq ORF | 1845 bp |
| Locus ID | 9572 |
| UniProt ID | P20393 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | Circadian rhythm - mammal |
| Gene Summary | This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Human IL10 Gene Repression by Rev-erba Ameliorates Mycobacterium tuberculosis Clearance
,Vemika Chandra, Sahil Mahajan, Ankita Saini, Hedwin K. Dkhar, Ravikanth Nanduri, Ella B. Raj, Ashwani Kumar, and Pawan Gupta,
J. Biol. Chem., Apr 2013; 288: 10692 - 10702.
,PubMed ID 23449984
[NR1D1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208915 | NR1D1 (Myc-DDK-tagged)-Human nuclear receptor subfamily 1, group D, member 1 (NR1D1) |
CNY 6,856.00 |
|
| RC208915L1 | Lenti ORF clone of Human nuclear receptor subfamily 1, group D, member 1 (NR1D1), Myc-DDK-tagged |
CNY 9,256.00 |
|
| RC208915L2 | Lenti ORF clone of Human nuclear receptor subfamily 1, group D, member 1 (NR1D1), mGFP tagged |
CNY 5,890.00 |
|
| RC208915L3 | Lenti ORF clone of Human nuclear receptor subfamily 1, group D, member 1 (NR1D1), Myc-DDK-tagged |
CNY 9,256.00 |
|
| RC208915L4 | Lenti ORF clone of Human nuclear receptor subfamily 1, group D, member 1 (NR1D1), mGFP tagged |
CNY 9,256.00 |
|
| RG208915 | NR1D1 (tGFP-tagged) - Human nuclear receptor subfamily 1, group D, member 1 (NR1D1) |
CNY 8,456.00 |
