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BACE2 (NM_138991) Human Untagged Clone
CAT＃: SC126981
BACE2 (untagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant c
CNY 3,656.00
CNY 7,410.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126981 sequence for NM_138991 edited (data generated by NextGen Sequencing)
ATGGGCGCACTGGCCCGGGCGCTGCTGCTGCCTCTGCTGGCCCAGTGGCTCCTGCGCGCC GCCCCGGAGCTGGCCCCCGCGCCCTTCACGCTGCCCCTCCGGGTGGCCGCGGCCACGAAC CGCGTAGTTGCGCCCACCCCGGGACCCGGGACCCCTGCCGAGCGCCACGCCGACGGCTTG GCGCTCGCCCTGGAGCCTGCCCTGGCGTCCCCCGCGGGCGCCGCCAACTTCTTGGCCATG GTAGACAACCTGCAGGGGGACTCTGGCCGCGGCTACTACCTGGAGATGCTGATCGGGACC CCCCCGCAGAAGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGA ACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCC AAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAA GACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATT TTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCT TATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACA CAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCT GGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAA GGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAA TTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCC ATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTG GAAGCTGTGGCCCGCGCATCNNNGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAAT TATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACG GTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCG AGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACA GAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATT GTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTG CTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCC TCTCTGGTCAGACATCGCTGGAAATGA Clone variation with respect to NM_138991.1 981 t=>n;982 c=>n;983 t=>n >OriGene 5' read for NM_138991 unedited
TACCCCCGCCCCGTTGGCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGC AGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCG AATTCGGCACGAGGGCCGAGTCGCTGAGCCGCGGCTGCCGGACGGGACGGGACCGGCTAG GCTGGGCGCGCCCCCCGGGCCCCGCCGTGGGCATGGGCGCACTGGCCCGGGCGCTGCTGC TGCCTCTGCTGGCCCAGTGGCTCCTGCGCGCCGCCCCGGAGCTGGCCCCCGCGCCCTTCA CGCTGCCCCTCCGGGTGGCCGCGGCCACGAACCGCGTAGTTGCGCCCACCCCGGGACCCG GGACCCCTGCCGAGCGCCACGCCGACGGCTTGGCGCTCGCCCTGGAGCCTGCCCTGGCGT CCCCCGCGGGCGCCGCCAACTTCTTGGCCATGGTAGACAACCTGCAGGGGGACTCTGGCC GCGGCTACTACCTGGAGATGCTGATCGGGACCCCCCCGCAGAAGCTACAGATTCTCGTTG ACACTGGAAGCAGTAACTTTGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACT TTGACACAGAGAGGTCTAGCACATACCGCTCCAGGGCTTTGACGTCACAGTGAAGTACAC ACAAGGAAGCTGGACGGGNCTTCGTGGGGAAGACCTCGTCACCATCCCCAAAGGGCTTCA TACTTCNTTTTCTTGTCAACATGCCACTATTNNTGATCAGAGAATTTCTTTTTGCCTGGG ATAAATGGGAATGGAATACTGGCCTAGCTATGCCCACTTGCAGCCATCAAGTCTCTGGAG ACTTCTCGACTCCTGGTGAACAGCAAATCCCCACGTTCTCATGCAAAGTGTTGAGCCGCT GCCGTGTTTGATCTGACAACGGGGAGATTGTTTTGGGGG >OriGene 3' read for NM_138991 unedited
ANAGTCGAGACCTTTCCTTTTTTTTTTAGTTCTTTCTCATCAAAACAGATTTATTATTTT TAAGCAAGGATAAGCATATGTGATAGTGGCCAGCTTGGGGATTGAACTCTTCCTGGTTGA TGCACAGTTCAACACCTTTTGGGTCTTGGCTGTTGGGATGATAATTCTTTTGGGTGAAGG GAAACAAGCCGTGGTCAAGGCTGCCTGCACCCCCATCCAGGCACAGGACCCTGGGCAAAG TCTCAAAAGAGGTAGTGTTTTTACTTTCGCACCAACAATACAACATAAGTATTGGGTACA AAAGAAGAAATTTCCTTCCCCTCTACCTCAACGGGCAAAAGGCCTTCCATCTTCAGAAGA GGCTTGTGAGGACCATCGGTTGATGACCTCCTAGTGAATTCTGGCTCCCATTCAGAGCAC AGAGAAACCCACAAAAGGGGCCTGTGGCTCTGGTTCCAGGTCTCAAGGGTACAGCTTGGT TACATCCCCAGGCCCCAGGCTGATTCTCCTGCCATCATACTGCAAGCCTTCCTGTACCAC TTTGNACCCAGTTGAGGTCTGGCGGAAAATAACCTCAAAGGCAATTAATACAAAAAGCTT CCTGTAAGCTAAGAAGGGTTATCAACTATATGTACTTATTTTTCCAGAGATTGAAGAGAG AAGAAACGAGCCAGGCTTTGGTTTTGGTTTATGGTTNNGTGCACATGTAAGAACTTTTGG CANTACANACCCCATAGAGCCTGCAGCCCATCCACTCTGTTTTTGTTTANAATGAAATTT TTTTTTTTAATATTTTCCTTGAATTGGGGGAGGATTTTAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_138991 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138991.1, NP_620476.1 |
| RefSeq Size | 2843 bp |
| RefSeq ORF | 1407 bp |
| Locus ID | 25825 |
| UniProt ID | Q9Y5Z0 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Protein Pathways | Alzheimer's disease |
| Gene Summary | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (c) lacks an alternate in-frame exon, compared to variant a. The encoded isoform (C) is shorter than isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224623 | BACE2 (Myc-DDK-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant c |
CNY 4,090.00 |
|
| RC224623L3 | Lenti-ORF clone of BACE2 (Myc-DDK-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant c |
CNY 5,990.00 |
|
| RC224623L4 | Lenti-ORF clone of BACE2 (mGFP-tagged)-Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant c |
CNY 5,990.00 |
|
| RG224623 | BACE2 (tGFP-tagged) - Human beta-site APP-cleaving enzyme 2 (BACE2), transcript variant c |
CNY 4,470.00 |
