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GABARAPL2 (NM_007285) Human Untagged Clone
CAT＃: SC126771
GABARAPL2 (untagged)-Human GABA(A) receptor-associated protein-like 2 (GABARAPL2)
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ATG8; ATG8C; GATE-16; GATE16; GEF-2; GEF2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126771 sequence for NM_007285 edited (data generated by NextGen Sequencing)
ATGAAGTGGATGTTCAAGGAGGACCACTCGCTGGAACACAGATGCGTGGAGTCCGCGAAG ATTCGAGCGAAATATCCCGACAGGGTTCCGGTGATTGTGGAAAAGGTCTCAGGCTCTCAG ATTGTTGACATTGACAAACGGAAGTACTTGGTTCCATCTGATATCACTGTGGCTCAGTTC ATGTGGATCATCAGGAAAAGGATCCAGCTTCCTTCTGAAAAGGCGATCTTCCTGTTTGTG GATAAGACAGTCCCACAGTCCAGCCTAACTATGGGACAGCTTTACGAGAAGGAAAAAGAT GAAGATGGATTCTTATATGTGGCCTACAGCGGAGAGAACACTTTTGGCTTCTGA Clone variation with respect to NM_007285.6 >OriGene 5' read for NM_007285 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTC GGCACGAGGGCCGCTGCCGCTGCCGCCGTCGTTGTTGTTGTGCTCGGTGCGCTGAGCTCC GCGGCTCCGCGAGCCGGTTCCGTCCCCTTCCCGCCGCCGCCATGAAGTGGATGTTCAAGG AGGACCACTCGCTGGAACACAGATGCGTGGAGTCCGCGAAGATTCGAGCGAAATATCCCG ACAGGGTTCCGGTGATTGTGGAAAAGGTCTCAGGCTCTCAGATTGTTGACATTGACAAAC GGAAGTACTTGGTTCCATCTGATATCACTGTGGCTCAGTTCATGTGGATCATCAGGAAAA GGATCCAGCTTCCTTCTGAAAAGGCGATCTTCCTGTTTGTGGATAAGACAGTCCCACAGT CCAGCCTAACTATGGGACAGCTTTACGAGAAGGAAAAAGATGAAGATGGATTCTTATATG TGGCCTACAGCGGAGAGAACACTTTTGGCTTCTGAGGGCCATTGCTGGGCTAGGTGCACC GTAACTGCTTGTGTATCTTGTAAATAGCCAGCCATTTTCAGTTATTATACCAGAACCTCT TCACATAGACCTATTAGTGCATCTGGTAACTGGATTTATTTCTTAATATATTGGAAAGCT TTGTCTTCTTACACTAGCAAATTATCATCCAGAGTCTCATTTTGAGCTTTTCCTTTTTGT GCATTGCCCTCATGCCTGTATTCTCCCAGGAAACTTGTCCTTCTGGACAATCATATTGGA TGATTTTCTCTATATCAAATGAGGGAGGTGCCGGATTAAAGTGAAAGGGAAGGTGGTCGC TTTAATCCTGGGTATGCCTGAATGTTAAAAGGCTAAGCTTAAAATTTCCCAATTAATCCC TACCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007285 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007285.5, NP_009216.1 |
| RefSeq Size | 450 bp |
| RefSeq ORF | 354 bp |
| Locus ID | 11345 |
| UniProt ID | P60520 |
| Domains | MAP1_LC3 |
| Protein Pathways | Regulation of autophagy |
| Gene Summary | Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206950 | GABARAPL2 (Myc-DDK-tagged)-Human GABA(A) receptor-associated protein-like 2 (GABARAPL2) |
CNY 1,200.00 |
|
| RC206950L1 | Lenti ORF clone of Human GABA(A) receptor-associated protein-like 2 (GABARAPL2), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC206950L2 | Lenti ORF clone of Human GABA(A) receptor-associated protein-like 2 (GABARAPL2), mGFP tagged |
CNY 5,890.00 |
|
| RC206950L3 | Lenti ORF clone of Human GABA(A) receptor-associated protein-like 2 (GABARAPL2), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC206950L4 | Lenti ORF clone of Human GABA(A) receptor-associated protein-like 2 (GABARAPL2), mGFP tagged |
CNY 3,600.00 |
|
| RG206950 | GABARAPL2 (tGFP-tagged) - Human GABA(A) receptor-associated protein-like 2 (GABARAPL2) |
CNY 2,800.00 |
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