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PJA2 (NM_014819) Human Untagged Clone
CAT＃: SC126706
PJA2 (untagged)-Human praja ring finger 2 (PJA2)
CNY 5,192.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Neurodap1; RNF131 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126706 sequence for NM_014819 edited (data generated by NextGen Sequencing)
ATGTCACAGTACACTGAAAAGGAGCCAGCAGCAATGGACCAAGAATCTGGTAAGGCTGTC TGGCCCAAACCAGCAGGAGGGTATCAGACAATTACAGGCAGGAGATATGGAAGAAGACAT GCTTATGTCAGTTTTAAACCATGTATGACCAGACATGAAAGAAGCTTAGGTCGGGCTGGT GATGACTATGAAGTGTTGGAACTAGATGATGTTCCAAAGGAAAATTCCTCAGGTTCCAGT CCTTTGGATCAAGTTGATTCTTCTTTACCCAGTGAACCTATATTTGAAAAAAGTGAAACA GAAATTCCCACTTGTGGTTCAGCATTGAATCAAACCACTGAGAGCAGTCAATCCTTTGTT GCAGTACATCACAGTGAGGAAGGCAGGGATACCTTAGGAAGCAGTACAAATCTTCATAAT CACTCTGAGGGAGAGTATATTCCAGGAGCTTGTAGTGCTTCAAGTGTCCAAAATGGAATT GCATTGGTTCATACAGACTCTTATGATCCAGATGGCAAACATGGAGAAGATAATGACCAT CTTCAACTTTCTGCAGAAGTCGTGGAAGGTAGTAGATACCAGGAATCATTAGGCAATACA GTATTTGAGTTGGAAAACAGAGAGGCAGAGGCATACACTGGTCTTTCACCACCAGTTCCC TCATTTAACTGTGAAGTAAGAGATGAGTTTGAAGAGTTAGATTCTGTACCATTAGTGAAA AGTTCTGCTGGTGATACTGAGTTTGTCCATCAGAATAGCCAGGAAATTCAGAGGTCTTCT CAAGATGAAATGGTTAGTACGAAACAACAAAATAATACTAGCCAGGAAAGACAGACAGAA CATTCACCTGAAGATGCAGCCTGTGGTCCAGGGCATATTTGTAGTGAACAAAATACCAAT GATAGGGAAAAGAACCATGGAAGTTCTCCTGAACAGGTAGTGAGGCCAAAAGTTAGAAAA CTGATAAGTTCAAGCCAGGTGGACCAAGAAACAGGTTTTAATAGGCATGAGGCGAAACAA AGAAGTGTTCAAAGATGGAGAGAGGCTTTGGAAGTTGAGGAAAGTGGCTCAGATGACCTC TTAATAAAATGTGAAGAATATGATGGAGAGCATGACTGTATGTTCTTGGATCCACCATAC TCAAGAGTTATTACACAAAGGGAAACAGAAAATAACCAAATGACATCAGAAAGTGGAGCC ACAGCAGGAAGGCAAGAAGTGGATAACACCTTTTGGAATGGCTGTGGAGATTATTACCAA CTCTATGACAAAGATGAAGATAGTTCTGAATGCAGTGATGGGGAATGGTCTGCTTCTTTG CCTCATCGATTTTCTGGTACAGAAAAAGATCAATCCTCAAGTGATGAAAGCTGGGAGACT CTGCCAGGAAAAGATGAGAATGAACCTGAGCTACAAAGTGATAGCAGTGGCCCTGAAGAA GAAAACCAAGAATTATCTCTTCAGGAAGGGGAACAGACATCCTTGGAAGAGGGAGAAATT CCTTGGTTACAGTACAATGAAGTCAATGAAAGCAGCAGTGATGAGGGAAATGAACCTGCC AATGAATTTGCACAGCCAGCTTTCATGTTGGATGGTAACAATAACCTGGAGGATGACTCC AGTGTGAGTGAAGACTTAGATGTGGATTGGAGCCTATTTGATGGCTTTGCAGATGGACTA GGAGTTGCTGAAGCTATTTCATATGTGGATCCTCAGTTCCTTACCTACATGGCACTAGAA GAACGCTTAGCCCAGGCTATGGAGACTGCTCTGGCCCATTTAGAGTCTCTTGCAGTGGAT GTTGAGGTGGCCAATCCACCAGCTAGTAAGGAAAGCATTGATGGTCTTCCAGAGACCCTT GTTCTTGAAGATCACACTGCTATTGGTCAGGAACAATGCTGTCCAATCTGTTGCAGTGAG TATATTAAGGATGATATAGCAACAGAGTTGCCCTGTCACCATTTCTTTCACAAACCTTGT GTCTCAATTTGGCTACAAAAGTCGGGAACATGCCCTGTGTGCCGCCGTCATTTCCCACCT GCGGTTATTGAAGCATCTGCAGCTCCTTCCTCTGAGCCTGATCCTGATGCCCCACCTTCA AATGACAGTATTGCAGAAGCACCCTAA Clone variation with respect to NM_014819.4 1218 g=>a >OriGene 5' read for NM_014819 unedited
GCCGCGAATTCGGCACCAGGCTTCGCGTTCGGCGGGGGAGGAGTTGGAGGCGGAGAAGAA GGCGGTGGTGGCGGGTGGAGGTTCGAGCGCTGTTCTCGCTCCGGAGCCGCTGCACATTTC GGAATCTTCTGCGGCTTGTCCATAGTGTGAATAAAAACTAAATCACATCTATAATTCTAC TGAACTGGTCACACAGACGCTGCCATATATGTCACAGTACACTGAAAAGGAGCCAGCAGC AATGGACCAAGAATCTGGTAAGGCTGTCTGGCCCAAACCAGCAGGAGGGTATCAGACAAT TACAGGCAGGAGATATGGAAGAAGACATGCTTATGTCAGTTTTAAACCATGTATGACCAG ACATGAAAGAAGCTTAGGTCGGGCTGGTGATGACTATGAAGTGTTGGAACTAGATGATGT TCCAAAGGAAAATTCCTCAGGTTCCAGTCCTTTGGATCAAGTTGATTCTTCTTTACCCAG TGAACCTATATTTGAAAAAAGTGAAACAGAAATTCCCACTTGTGGTTCAGCATTGAATCA AACCACTGAGAGCAGTCAATCCTTTGTTGCAGTACATCACAGTGAGGAAGGCAGGGATAC CTTAGGAAGCAGTACAAATCTTCATAATCACTCTGAGGGAGAGTATATTCCAGGAGCTTG TAGTGCTTCAAGTGTCCAAATGGAATTGCATTGGTTCATACAGACTCTTATGATCCAGAT GGGCAACATGGAGAAAGATAT >OriGene 3' read for NM_014819 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAATT TAAGCCAACTCTTATTCAACTTTTCTTCTTCACAGCAGCTGTTTATAGATAGTAGGGAGC CAAGAATGAAGGACAGTAACAGATGGAAAGCAAAAAGTACAACAGCTATCTTAAGTTCAG CTCTCAACATTGCTGGTTGAGTTTGGAACCAAAACCTCTTAACAACTGGCAGATAATAGC TAAATCTTAACAGACAAAGAAGAAATATTTTCTTTGGGACAGCTGCTATCTAAAAAAAAA CCAAGGTCCCTTAATATAGTCTAAATATAATGTGTGGCTTATTATAGAGAAATCTTTAGC AACGTAAGTTTAACCAGTAAGTGTCACAACTGATCAACAGTACTTAAAAGGAAACAAACA AAAATCACACTAGCCACAAATTTCCACCATATACACATGAAATTAATTTTAATCTGTTTT GACTCCTTGACACTAACTGATCATTAATGAAATATGATATGGAAAGATCACAGAGTAGAA AACAAGCAAAGATTAGTTTATACAACAGTGACTATATACATCAGAGGGAAAACATGCTAG CTAATGCAACATTAAGGCCTGAATGTAAGCATTCCCCAAGCCACAGAAGCCCCAAAGAAC TCCTAAATTACAAATTCATCACATTACATGCATGCCATGTTCACTTTTGTTTTACCCATA AAGGGATACACCGATTTTTGCTGTAAATACCCAGACCCTTNTACAATATATGCAAAAATT AGCATCGCAAGTGTTTTGTTCCTTATTTTTAACCCTCTATTGGCCAACAGCGAAAATTTA TTCTTTTCAAAATGAAAAAGCGCACGGCTCTAACCTCTAAAAACACCCCATCAAAAGACC TTTGTTTTGGCAGACTATAAACTTCTTTTTGTTCCCAACCATTTTCAGGCCACCCAACGC ACACCCCCCTCGGGTTAACTTACCCTGGCACAGGTCCCACGCCCCTCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014819 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014819.2, NP_055634.2 |
| RefSeq Size | 4789 bp |
| RefSeq ORF | 2127 bp |
| Locus ID | 9867 |
| UniProt ID | O43164 |
| Domains | RING |
| Protein Families | Druggable Genome |
| Gene Summary | Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes. Through the ubiquitination of MFHAS1, positively regulates the TLR2 signaling pathway that leads to the activation of the downstream p38 and JNK MAP kinases and promotes the polarization of macrophages toward the pro-inflammatory M1 phenotype (PubMed:28471450).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205204 | PJA2 (Myc-DDK-tagged)-Human praja ring finger 2 (PJA2) |
CNY 5,184.00 |
|
| RC205204L1 | Lenti ORF clone of Human praja ring finger 2 (PJA2), Myc-DDK-tagged |
CNY 7,584.00 |
|
| RC205204L2 | Lenti ORF clone of Human praja ring finger 2 (PJA2), mGFP tagged |
CNY 7,700.00 |
|
| RC205204L3 | Lenti ORF clone of Human praja ring finger 2 (PJA2), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC205204L4 | Lenti ORF clone of Human praja ring finger 2 (PJA2), mGFP tagged |
CNY 7,700.00 |
|
| RG205204 | PJA2 (tGFP-tagged) - Human praja ring finger 2 (PJA2) |
CNY 6,784.00 |
