United States
Germany
Japan
United Kingdom
China
C1S (NM_201442) Human Untagged Clone
CAT＃: SC126504
C1S (untagged)-Human complement component 1, s subcomponent (C1S), transcript variant 1
CNY 5,048.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EDSPD2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126504 sequence for NM_201442 edited (data generated by NextGen Sequencing)
ATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTATGCTGAGCCTACCATGTAT GGGGAGATCCTGTCCCCTAACTATCCTCAGGCATATCCCAGTGAGGTAGAGAAATCTTGG GACATAGAAGTTCCTGAAGGGTATGGGATTCACCTCTACTTCACCCATCTGGACATTGAG CTGTCAGAGAACTGTGCGTATGACTCAGTGCAGATAATCTCAGGAGACACTGAAGAAGGG AGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTCCAATTGTGGAAGAGTTCCAA GTCCCATACAACAAACTCCAGGTGATCTTTAAGTCAGACTTTTCCAATGAAGAGCGTTTT ACGGGGTTTGCTGCATACTATGTTGCCACAGACATAAATGAATGCACAGATTTTGTAGAT GTCCCTTGTAGCCACTTCTGCAACAATTTCATTGGTGGTTACTTCTGCTCCTGCCCCCCG GAATATTTCCTCCATGATGACATGAAGAATTGCGGAGTTAATTGCAGTGGGGATGTATTC ACTGCACTGATTGGGGAGATTGCAAGTCCCAATTATCCCAAACCATATCCAGAGAACTCA AGGTGTGAATACCAGATCCGGTTGGAGAAAGGGTTCCAAGTGGTGGTGACCTTGCGGAGA GAAGATTTTGATGTGGAAGCAGCTGACTCAGCGGGAAACTGCCTTGACAGTTTAGTTTTT GTTGCAGGAGATCGGCAATTTGGTCCTTACTGTGGTCATGGATTCCCTGGGCCTCTAAAT ATTGAAACCAAGAGTAATGCTCTTGATATCATCTTCCAAACTGATCTAACAGGGCAAAAA AAGGGCTGGAAACTTCGCTATCATGGAGATCCAATGCCCTGCCCTAAGGAAGACACTCCC AATTCTGTTTGGGAGCCTGCGAAGGCAAAATATGTCTTTAGAGATGTGGTGCAGATAACC TGTCTGGATGGGTTTGAAGTTGTGGAGGGACGTGTTGGTGCAACATCTTTCTATTCGACT TGTCAAAGCAATGGAAAGTGGAGTAATTCCAAACTGAAATGTCAACCTGTGGACTGTGGC ATTCCTGAATCCATTGAGAATGGTAAAGTTGAAGACCCAGAGAGCACTTTGTTTGGTTCT GTCATCCGCTACACTTGTGAGGAGCCATATTACTACATGGAAAATGGAGGAGGTGGGGAG TATCACTGTGCTGGTAACGGGAGCTGGGTGAATGAGGTGCTGGGCCCGGAGCTGCCGAAA TGTGTTCCAGTCTGTGGAGTCCCCAGAGAACCCTTTGAAGAAAAACAGAGGATAATTGGA GGATCCGATGCAGATATTAAAAACTTCCCCTGGCAAGTCTTCTTTGACAACCCATGGGCT GGTGGAGCGCTCATTAATGAGTACTGGGTGCTGACGGCTGCTCATGTTGTGGAGGGAAAC AGGGAGCCAACAATGTATGTTGGGTCCACCTCAGTGCAGACCTCACGGCTGGCAAAATCC AAGATGCTCACTCCTGAGCATGTGTTTATTCATCCGGGATGGAAGCTGCTGGAAGTCCCA GAAGGACGAACCAATTTTGATAATGACATTGCACTGGTGCGGCTGAAAGACCCAGTGAAA ATGGGACCCACCGTCTCTCCCATCTGCCTACCAGGCACCTCTTCCGACTACAACCTCATG GATGGGGACCTGGGACTGATCTCAGGCTGGGGCCGAACAGAGAAGAGAGATCGTGCTGTT CGCCTCAAGGCGGCAAGGTTACCTGTAGCTCCTTTAAGAAAATGCAAAGAAGTGAAAGTG GAGAAACCCACAGCAGATGCAGAGGCCTATGTTTTCACTCCTAACATGATCTGTGCTGGA GGAGAGAAGGGCATGGATAGCTGTAAAGGGGACAGTGGTGGGGCCTTTGCTGTACAGGAT CCCAATGACAAGACCAAATTCTACGCAGCTGGCCTGGTGTCCTGGGGGCCCCAGTGTGGG ACCTATGGGCTCTACACACGGGTAAAGAACTATGTTGACTGGATAATGAAGACTATGCAG GAAAATAGCACCCCCCGTGAGGACTAA Clone variation with respect to NM_201442.2 >OriGene 5' read for NM_201442 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTCGGGTAGGGAATCT TATGAACAGAACCAGGACAGGGAGGCTGGCCGGAGGTTCCTGCAGAGGGAGCGTCAAGGC CCTGTGCTGCTGTCCCTGGGGGCCAGAGGGGTTGCCCAGCATGCCCACTGGCAGGAGAGA GGGAACTGACCCACTTGCTCCTACCAGCTTCTGAAGGTGACACTGAGCCCCAGGTGACGC CGCACCACCAAAGAAGGTGCTTGTGTTTGTCAGACAAATACAGCCAGGCCTGCCACCCCT TAGGCTCCAAAGTCCGGAGGTGCAGAAAGCCAGGACCAAGAGACAGGCAGCTCACCAGGG TGGACAAATCGCCAGAGATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTATG CTGAGCCTACCATGTATGGGGAGATCCTGTCCCCTAACTATCCTCAGGCATATCCCAGTG AGGTAGAGAAATCTTGGGACATAGAAGTTCCTGAAGGGTATGGGATTCACCTCTACTTCA CCCATCTGGACATTGAGCTGTCAGAGAACTGTGCGTATGACTCAGTGCAGATAATCTCAG GAGACACTGAAGAANGGAGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTCCAA TTGTGGAAGAGTTCCCAGTCCCATACCACANACTCCAGGTGATCTTTAAGTCAGACTTTT TCCATGAAGAGCGTTNTACGGGGTTTGCTGCATACTATGTTGCCACAGACATAAATGAAT GCACAGATTNNTGTAGATGTCCCCTTGTACCCCACTTCTGCACAATTTCATTGGTGGTTA CCTTCTGCTNCCGGCCCCCCGAATATTTCCTCCATGATGACATGAAGAATGGCCGGAGTA AATGCAGTGGGGATTGGATCAC >OriGene 3' read for NM_201442 unedited
CTATGGAACGCGGCACGCTTTCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGCTTATAAAC ATCCTTTATTGTACATAGACAGTGGATACTGAGAATGATCAAGTAAATGGAATTTTGAAC AGGTAAAGAGGAAACAAAGAATTAAGGTATCCCTGTGGAATAGTGCAAGAAAGGAGTGCC CCACCCATAGTGTTATCTACAATAGGTACTCCGGGGAAAGGACCCCAAGGAGTCAGACCA CAAATGTATGACCAGCACAATTCTATGATCAAACTCTACCTCTAGCAAGGCGTCTCAACA ATCAAGTTCTATTTAAATCATTCGCTCGTGTCTTCTTTCAGTCATGATGAAATAATGAGA ATATCATAAGGAACAGAAGGTAATGCATTGGTCACCACCCTTGGAGAGGCTGGTGGGATG TATCTGGATTAGTCCTCACGGGGGGTGCTATTTTCCTGCATAGTCTTCATTATCCAGTCA ACATAGTTCTTTACCCGTGTGTAGAGCCCATAGGTCCCACACTGGGGCCCCCAGGACACC AGGCCAGCTGCGTAGAATTTGGTCTTGTCATTGGGATCCTGTACAGCAAAGGCCCCACCA CTGTCCCCTTTACAGCTATCCATGCCCTTCTCTCCTCCAGCACAGATCATGTTAGGAGTG AAAACATAAGCCTCTGCATCTGCTGTGGGTTTCTCCACTTTCACTTCTTTGCATTTTCTT AAAGGAGCTACAGGTAACCTTGCCGCCTTGAAGCGAACAGCACGATCTCTCTTCTCTGTT CGGCCCCAGCCTGAGATCAGTCCCAGGTCCCATCCATGAGTTGTANTCGGAAAAAGTGCC TGTAAGCACATGGAAGATACGTGGGGTCCATTTTCACTGGGTCTTTCAGCCGCACCATGC AATGTCATATCAAAATGGNTCGTCCTTCGGGACTTCACAGCTTCCTCCCGGTGAATTACC ATGCTCAGGATGAGCTCTGGATTTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_201442 |
| Insert Size | 2900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_201442.1, NP_958850.1 |
| RefSeq Size | 2813 bp |
| RefSeq ORF | 2067 bp |
| Locus ID | 716 |
| UniProt ID | P09871 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Complement and coagulation cascades, Systemic lupus erythematosus |
| Gene Summary | This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Classical complement pathway components c1r and c1s: purification from human serum and in recombinant form and functional characterization
,Rossi, V;Bally, I;Lacroix, M;Arlaud, GJ;Thielens, NM;,
Methods Mol. Biol. 43-60
,PubMed ID 24218249
[C1S]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208948 | C1S (Myc-DDK-tagged)-Human complement component 1, s subcomponent (C1S), transcript variant 1 |
CNY 5,040.00 |
|
| RC208948L1 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 1, Myc-DDK-tagged |
CNY 7,440.00 |
|
| RC208948L2 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC208948L3 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208948L4 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG208948 | C1S (tGFP-tagged) - Human complement component 1, s subcomponent (C1S), transcript variant 1 |
CNY 4,370.00 |
