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CNOT1 (NM_206999) Human Untagged Clone
CAT＃: SC126464
CNOT1 (untagged)-Human CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2
CN¥ 10,450.00
货期*
4周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AD-005; CDC39; HPE12; NOT1; NOT1H |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_206999 edited
CGGAGCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAGGGGGTCGAGGAGAGCCGG AGTCGGGGACCCAGGAGTTTCCTGTGTCCAGCGCTGCCGGAGCCGCCTGAGGTGCCATGT TTCAGAACAGAGTAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGAT ATAGCCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTGACTAAAGGGGAATAATGG TGATTTTGCGCCGGGCTCGGCCGCCTGCTTCCGCCCCAACCAGCAATGAATCTTGACTCG CTCTCGCTGGCCTTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTAC CGAGCCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCACGGTCCTGAGGCAGACAGG CATTTATTACGCTGCCTATTTTCGCATGTGGATTTCAGTGGCGATGGTAAAAGCAGTGGC AAAGATTTCCATCAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCA AATTTTATCTCGACGCTGTCCTATGCCATTGATAATCCATTGCACTATCAGAAGAGTTTA AAGCCTGCACCCCACTTATTTGCCCAGCTGAGTAAAGTGCTCAAATTAAGCAAAGTACAA GAGGTAATTTTTGGCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTCGCT GCCCAGTTTATCAAACAGAAGCTTCCAGATCTTCTGCGTTCTTACATTGACGCAGACGTC AGTGGAAATCAAGAAGGTGGCTTCCAAGATATAGCAATAGAGGTCCTACACCTCCTCCTC TCCCATCTCCTCTTTGGGCAGAAGGGAGCCTTTGGAGTTGGACAAGAACAGATAGACGCT TTTCTTAAGACGCTGCGCAGAGATTTTCCCCAAGAACGCTGTCCCGTGGTGCTCGCACCA CTTTTATACCCTGAAAAACGGGACATTCTAATGGACAGGATCCTGCCTGATTCCGGAGGG GTAGCTAAAACCATGATGGAGAGCTCTTTGGCTGATTTCATGCAAGAAGTAGGCTATGGC TTTTGTGCAAGTATTGAAGAATGTCGCAATATAATCGTGCAGTTTGGTGTTCGGGAGGTC ACAGCTGCCCAGGTTGCAAGGGTTTTGGGAATGATGGCTCGAACTCATTCAGGGTTAACA GATGGCATTCCATTACAGAGTATTTCTGCTCCGGGCAGTGGGATCTGGAGTGATGGGAAA GATAAAAGTGATGGAGCACAGGCACACACATGGAATGTAGAAGTCTTGATTGACGTTCTT AAAGAACTGAATCCAAGTTTGAATTTCAAGGAAGTAACTTATGAACTGGACCATCCTGGA TTTCAAATTCGTGACAGTAAAGGACTTCATAATGTGGTTTATGGCATTCAGAGGGGTTTG GGTATGGAAGTGTTCCCAGTAGACCTCATATATAGACCTTGGAAACATGCTGAAGGCCAG CTCTCCTTCATTCAACATTCCCTTATAAATCCAGAGATCTTCTGTTTTGCTGACTATCCC TGTCATACTGTTGCCACTGATATTCTGAAAGCACCACCAGAGGATGACAATCGAGAAATT GCCACATGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGGCTTGCAGAGGTTGGGCAG TATGAGCAAGTCAAACAGCTCTTCAGCTTCCCTATCAAACACTGTCCAGACATGCTGGTA TTGGCCTTACTACAAATTAACACCTCTTGGCATACCTTGCGCCATGAACTTATCTCCACT CTGATGCCAATTTTCCTTGGAAACCATCCTAACTCAGCTATTATTTTGCACTATGCATGG CATGGGCAGGGACAGTCTCCCTCAATTCGCCAACTTATCATGCATGCAATGGCAGAATGG TACATGAGAGGGGAGCAGTATGATCAGGCCAAATTGTCTCGAATACTTGATGTGGCCCAG GACTTGAAGGCCTTGTCAATGCTGCTAAATGGTACTCCATTTGCCTTTGTTATTGACCTT GCTGCACTTGCTTCACGTCGTGAATACCTCAAACTTGATAAGTGGCTCACAGCTAAAATT CGAGAGCATGGGGAGCCTTTTATCCAGGCGTGTATGACTTTTTTAAAGAGACGGTGTCCT TCTATTTTGGGCGGACTTGCCCCAGAAAAAGACCAGCCCAAAAGTGCTCAACTTCCTCCA GAAACTTTGGCGACAATGTTGGCCTGTCTGCAAGCTTGTGCAGGGAGTGTTTCTCAGGAG CTATCAGAAACTATCCTCACCATGGTAGCCAATTGCAGTAATGTTATGAATAAGGCCAGA CAACCACCACCTGGAGTTATGCCAAAAGGACGTCCTCCTAGTGCTAGCAGCTTAGATGCC ATTTCTCCTGTTCAGATTGACCCTCTTGCTGGAATGACATCTCTTAGTATAGGTGGTTCA GCTGCCCCTCACACCCAGAGTATGCAGGGTTTTCCTCCAAATTTGGGTTCTGCATTCAGT ACCCCTCAGTCACCAGCAAAAGCATTTCCACCCCTTTCAACCCCCAATCAGACCACTGCA TTCAGTGGTATTGGAGGACTTTCATCACAGCTTCCAGTAGGTGGTCTTGGCACAGGCAGC CTGACTGGTATAGGAACTGGTGCTCTTGGACTCCCTGCAGTGAATAACGACCCTTTTGTA CAGAGGAAACTGGGCACCTCTGGACTGAATCAGCCTACATTCCAGCAGAGTAAGATGAAA CCTTCGGACTTGTCTCAGGTGTGGCCAGAGGCAAACCAGCACTTTAGTAAAGAGATAGAT GATGAAGCAAACAGCTATTTCCAGCGAATATATAATCATCCACCACATCCAACCATGTCT GTTGATGAGGTATTAGAAATGCTGCAGAGATTTAAAGACTCTACTATAAAGAGGGAACGA GAAGTATTTAACTGTATGCTAAGGAACTTGTTTGAAGAATATCGTTTTTTTCCCCAGTAT CCTGATAAAGAGTTACATATAACAGCCTGCCTATTTGGTGGTATAATTGAGAAAGGACTG GTCACTTACATGGCACTAGGTCTGGCTCTACGATATGTTCTTGAAGCCTTACGCAAGCCT TTTGGATCCAAAATGTATTATTTCGGGATTGCTGCACTAGATAGATTTAAAAACAGATTG AAGGACTATCCCCAGTATTGTCAGCATTTGGCTTCTATCAGTCACTTTATGCAATTTCCA CATCATTTACAGGAGTATATTGAGTATGGACAGCAGTCTAGAGATCCTCCTGTGAAAATG CAAGGCTCTATCACAACCCCTGGAAGTATTGCACTGGCTCAGGCCCAGGCTCAGGCCCAG GTTCCAGCAAAAGCTCCTCTTGCTGGTCAAGTTAGCACTATGGTAACCACCTCAACAACT ACCACTGTTGCTAAAACGGTTACGGTCACCAGGCCAACTGGAGTCAGCTTTAAGAAAGAT GTGCCACCTTCTATTAATACTACAAATATAGATACGTTGCTTGTGGCCACAGATCAAACT GAGAGAATTGTGGAGCCCCCAGAAAATATCCAGGAGAAAATTGCTTTTATTTTCAATAAT CTCTCACAGTCAAATATGACACAAAAGGTTGAAGAGCTAAAGGAAACGGTGAAAGAAGAA TTTATGCCTTGGGTTTCACAGTATCTGGTTATGAAGAGAGTCAGTATTGAGCCAAACTTT CATAGCCTGTATTCAAACTTCCTTGACACGCTGAAGAATCCTGAATTTAACAAGATGGTT CTGAATGAGACCTACAGAAACATTAAAGTGCTCCTGACCTCTGATAAAGCTGCAGCCAAT TTCTCAGATCGTTCTTTGCTGAAGAACTTGGGACATTGGCTAGGAATGATCACATTAGCT AAAAACAAACCCATCTTACACACTGACTTGGATGTGAAATCATTGCTGCTAGAGGCTTAT GTTAAAGGACAACAAGAATTGCTCTATGTAGTGCCCTTTGTTGCCAAAGTCTTAGAATCT AGCATTCGTAGTGTGGTTTTTAGGCCACCAAACCCTTGGACAATGGCAATTATGAATGTA TTAGCTGAGCTACATCAGGAGCATGACTTAAAGTTAAACTTGAAGTTTGAAATCGAGGTT CTCTGCAAGAACCTTGCATTAGACATCAATGAGCTAAAACCTGGAAACCTCCTAAAGGAT AAAGATCGCCTGAAGAATTTAGATGAGCAACTCTCTGCTCCAAAGAAAGATGTCAAGCAG CCAGAAGAACTCCCTCCCATCACAACCACAACAACTTCTACTACACCAGCTACCAACACC ACTTGTACAGCCACGGTTCCACCACAGCCACAGTACAGCTACCACGACATCAATGTCTAT TCCCTTGCGGGCTTGGCACCACACATTACTCTGAATCCAACAATTCCCTTGTTTCAGGCC CATCCACAGTTGAAGCAGTGTGTGCGTCAGGCAATTGAACGGGCTGTCCAGGAGCTGGTC CATCCTGTGGTGGATCGATCAATTAAGATTGCCATGACTACTTGTGAGCAAATAGTCAGG AAGGATTTTGCCCTGGATTCGGAGGAATCTCGAATGCGAATAGCAGCTCATCACATGATG CGTAACTTGACAGCTGGAATGGCTATGATTACATGCAGGGAACCTTTGCTCATGAGCATA TCTACCAACTTAAAAAACAGTTTTGCCTCAGCCCTTCGTGTAAGTTGGCTATTTCCTTGG TATAGGTACAAAACGTATTACTGCTTGTCTGTAATAATTTTTTTCTTTGTCTATATATGG CACTGGGCGTTACCACTTATTCTTAATAATCACCATATTTGTTTGATGTCTTCCATCATT TTAGATTGTAATTCTGTGAGGCAAAGCATCATGTCTGTGTGTTTTTTTTTTTTTCTGTTA TATTCTCAACACGATGTTTGACAGATAGTAGATACCCAAATATTTGTTGGTTTAAATAAA TTAAGATTTAAAAAGGAAAAAAAAAAAAAAA >OriGene 5' read for NM_206999 unedited
NGCGGTTCGGATTTTGTAATACGACTTACTATAGGCGGCCGCATAACTTCGTATAGCATA CATTATATTAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGCG GAGCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAGGGGGTCGAGGAGAGCCGGAG TCGGGGACCCAGGAGTTTCCTGTGTCCAGCGCTGCCGGAGCCGCCTGAGGTGCCATGTTT CAGAACAGAGTAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGATAT AGCCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTGACTAAAGGGGAATAATGGTG ATTTTGCGCCGGGCTCGGCCGCCTGCTTCCGCCCCAACCAGCAATGAATCTTGACTCGCT CTCGCTGGCCTTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTACCG AGCCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCACGGTCCTGAGGCAGACAGGCA TTTATTACGCTGCCTATTTTCGCATGTGGATTTCAGTGGCGATGGTAAAAGCAGTGGCAA AGATTTCCATCAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCAAA TTTTATCTCGACGCTGTCCTATGCCATTGATAATCCATTGCACTATCAGAAGAGTTTAAA GCCTGCACCCCACTTATTTGCCCCAGCTGAGTAAAGTGCTCAAATTAAGCAAAGTACAAG AGGTAAATTTTGGCCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTTCGC TGCCCATTTTATAAAAAAGAAGCTTCCCGATACCCTGCGTTTTTTACATTGACGCAGCAG TCAGTGGGAATTCAGA |
| Restriction Sites | Please inquire |
| ACCN | NM_206999 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_206999.1, NP_996882.1 |
| RefSeq Size | 5019 bp |
| RefSeq ORF | 4656 bp |
| Locus ID | 23019 |
| UniProt ID | A5YKK6 |
| Protein Pathways | RNA degradation |
| Gene Summary | Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3' UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of embryonic stem (ES) cell identity.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. The encoded isoform (b) is shorter and has a distinct C-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206903 | CNOT1 (Myc-DDK-tagged)-Human CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2 |
CN¥ 16,976.00 |
|
| RC206903L3 | Lenti-ORF clone of CNOT1 (Myc-DDK-tagged)-Human CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2 |
CN¥ 7,600.00 |
|
| RC206903L4 | Lenti-ORF clone of CNOT1 (mGFP-tagged)-Human CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2 |
CN¥ 7,600.00 |
|
| RG206903 | CNOT1 (tGFP-tagged) - Human CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2 |
CN¥ 18,576.00 |
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