LRDD (PIDD1) (NM_145887) Human Untagged Clone
CAT#: SC126225
PIDD (untagged)-Human p53-induced death domain protein (PIDD), transcript variant 3
CNY 6,552.00
Cited in 1 publication. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | LRDD; PIDD |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_145887 edited
GCTGCTGGCGCTTCCCCGGGCGCTGCCTGGACAGGCCTGCCTGCGTGCTGGGACATGTCT GGCCTCCAAGGACCGTCGGTGGGCGATGGCTGCAACGGTGGAGGGGCCAGAGCTGGAGGC AGCTGCTGCCGCAGGAGATGCTTCAGAGGATTCGGACGCAGGGTCCAGGGCGCTGCCTTT CCTGGGCGGCAACCGGCTGAGCTTGGACCTGTACCCCGGGGGCTGCCAGCAGCTGCTGCA CCTGTGTGTCCAGCAGCCTCTTCAGCTGCTGCAGGTGGAATTCTTGCGTCTGAGCACTCA CGAGGACCCTCAGCTGCTGGAGGCCACCCTGGCCCAGCTGCCTCAGAGCCTGTCCTGCCT CCGCTCCCTGGTCCTCAAAGGAGGGCAACGCCGGGACACACTGGGTGCCTGTCTCCGGGG TGCCCTGACCAACCTGCCCGCTGGTCTGAGTGGCCTGGCCCATCTGGCCCACCTGGACCT GAGCTTCAACAGCCTGGAGACACTGCCGGCCTGTGTCCTGCAGATGCGAGGTCTGGGTGC GCTCTTGCTGTCTCACAACTGCCTCTCTGAGCTGCCTGAGGCTCTGGGGGCCCTCCCCGC CCTCACCTTCCTCACAGTGACACACAACCGCCTGCAGACGCTGCCCCCAGCACTGGGGGC CCTATCCACCCTGCAGCGCCTCGATCTCTCTCAGAATCTGCTGGACACGCTACCTCCTGA GATTGGAGGCCTGGGCAGCCTCCTGGAGCTCAACCTGGCCTCCAACCGGCTGCAGAGCCT CCCAGCCTCTCTGGCGGGACTTCGGTCCTTGCGGCTCCTTGTCCTGCACAGCAACCTCCT GGCCTCTGTGCCAGCTGACTTGGCCCGCCTTCCACTCCTCACCCGGCTCGACCTGAGGGA CAACCAGCTCCGGGACCTGCCCCCTGAGCTGCTAGACGCCCCCTTTGTGCGCCTGCAGGG GAACCCCCTGGGTGAGGCCTCGCCAGACGCCCCGAGTTCACCAGTGGCAGCCCTCATTCC AGAAATGCCCAGACTGTTCCTGACCTCAGATTTGGACAGCTTTCCTGTGACCCCTCGAGG CTGCTCAGTGACCCTGGCCTGTGGCGTCCGCCTGCAGTTCCCAGCGGGAGCCACCGCCAC CCCCATCACCATCCGCTATCGGCTGCTGCTGCCGGAGCCAGGCCTCGTCCCCCTGGGTCC TCATGACGCCCTGCTCAGCCATGTGCTGGAGCTGCAGCCCCATGGGGTGGCCTTCCAGCA GGATGTGGGGCTGTGGCTGCTCTTCACCCCACCGCAGGCCCGGCGCTGCCGTGAAGTGGT GGTCAGGACCCGGAATGACAACAGCTGGGGTGACCTGGAGACCTACCTGGAGGAAGAGGC ACCCCAGCGGCTCTGGGCTCACTGCCAGGTGCCCCACTTCTCCTGGTTCCTTGTGGTTTC CCGCCCTGTGTCCAATGCCTGCCTGGTGCCACCGGAGGGGACACTGCTGTGCTCCTCGGG TCATCCTGGGGTCAAAGTCATCTTCCCCCCTGGGGCCACTGAGGAGCCTCGTCGAGTCTC CATGCAGGTGGTGCGCATGGCTGGCCGAGAGCTGCAGGCCCTCCTGGGAGAACCAGAGGC TGCAGTGAGCCCCCTGCTGTGCCTGTCACAGAGCGGTCCCCCCAGCTTCCTCCAACCGGT CACCGTGCAGCTGCCTCTGCCCTCTGGCATCACAGGCCTCAGTCTGGACCGCTCCCGCCT GCACCTGTTGTACTGGGCCCCTCCTGCAGCCACCTGGGATGACATCACAGCTCAGGTGGT CCTGGAGCTCACCCACCTGTACGCACGCTTCCAGGTCACACACTTCTCCTGGTACTGGCT CTGGTACACCACCAAGAACTGTGTGGGAGGCCTGGCTCGGAAGGCCTGGGAGCGGCTGCG GCTGCACCGTGTGAACCTCATCGCTCTGCAGCGGCGCCGGGACCCTGAGCAGGTCCTGCT GCAGTGCCTGCCCCGAAACAAGGTGGACGCCACCCTTCGGCGGCTGCTGGAGCGGTACCG GGGCCCCGAGCCCTCTGACACGGTGGAGATGTTCGAGGGCGAAGAGTTCTTTGCGGCCTT CGAGCGCGGCATCGACGTGGATGCTGACCGCCCTGACTGTGTGGAGGGCAGAATCTGCTT TGTCTTCTACTCGCACCTGAAGAATGTGAAGGAGGTGTCCTTCTACCGTGGCGCGGTGCC TGTGCGGGTGCCCGAGGAGGCTGAGGCTGCCCGGCAGAGGAAGGGCGCAGACGCCCTGTG GATGGCCACTCTGCCCATCAAGCTGCCGAGACTTCGAGGGTCCGAGGGGCCACGGCGGGG GGCTGGCCTCTCCTTGGCACCCTTGAATCTGGGAGATGCCGAGACCGGCTTTCTGACGCA GAGCAACCTGCTGAGTGTGGCTGGGCGTCTGGGTCTGGACTGGCCAGCCGTGGCCCTGCA CCTGGGGGTGTCCTACCGGGAGGTGCAGCGCATCCGGCACGAGTTCCGGGATGATCTGGA TGAGCAGATCCGTCACATGCTCTTCTCCTGGGCTGAGCGCCAGGCTGGGCAGCCAGGGGC TGTGGGGCTCCTGGTGCAGGCCCTGGAGCAGAGTGACCGGCAGGACGTGGCTGAAGAGGT GCGCGCAGTCTTGGAGCTCGGCCGCCGCAAGTACCAGGACAGCATCCGACGCATGGGCTT GGCCCCCAAGGACCCCGCTCTGCCTGGCTCCTCGGCTCCACAGCCCCCAGAGCCTGCCCA GGCCTAGGCCCCACAGACTTTTAGGCTGGCCCAGATATTCCCCAGTGGATGGGCAGAGCC CCCACCTTCAAGTCTCTCCAGTGTGTGGGGACGGGTCCCTGTGAGCAACAAAACTGCACT GTTTCTTTCAAAAAAAAAAAAAAAA >OriGene 5' read for NM_145887 unedited
TTCAGTGATCTTATATTTGTCATACGACTTTACTATAGGCGGCCGCGTAATCACATCTGG TACCGGCTCCGTAATTCCCGGGATATCGTCGACCCACGCGTCCGGCTGCTGGCGCTTCCC CGGGCGCTGCCTGGACAGGCCTGCCTGCGTGCTGGGACATGTCTGGCCTCCAAGGACCGT CGGTGGGCGATGGCTGCAACGGTGGAGGGGCCAGAGCTGGAGGCAGCTGCTGCCGCAGGA GATGCTTCAGAGGATTCGGACGCAGGGTCCAGGGCGCTGCCTTTCCTGGGCGGCAACCGG CTGAGCTTGGACCTGTACCCCGGGGGCTGCCAGCAGCTGCTGCACCTGTGTGTCCAGCAG CCTCTTCAGCTGCTGCAGGTGGAATTCTTGCGTCTGAGCACTCACGAGGACCCTCAGCTG CTGGAGGCCACCCTGGCCCAGCTGCCTCAGAGCCTGTCCTGCCTCCGCTCCCTGGTCCTC AAAGGAGGGCAACGCCGGGACACACTGGGTGCCTGTCTCCGGGGTGCCCTGACCAACCTG CCCGCTGGTCTGAGTGGCCTGGCCCATCTGGCCCACCTGGACCTGAGCTTCAACAGCCTG GAGACACTGCCGGCCTGTGTCCTGCAGATGCGAGGTCTGGGTGCGCTCTTGCTGTCTCAC AACTGCCTCTCTGAGCTGCCTGAGGCTCTGGGGGCCCTCCCCGCCCTCACCTTCCTCACA GTGACACACAACCGCCTGCAGACGCTGCCCCCAGCACTGGGGGCCCTATCCACCCTGCAG CGCCTCGATCTCTCTCAGAATCTGCTGGACACGCTACCTCCTGAGAATTGGNAGGCCTGG GCAGCCTCCTTGGAGCTTAAACCTGGCCCTCCACCCGGCTGCAGAAGCCTCCCAGCCTCT CTGGGGGG |
Restriction Sites | Please inquire |
ACCN | NM_145887 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_145887.2, NP_665894.2 |
RefSeq Size | 2902 bp |
RefSeq ORF | 2682 bp |
Locus ID | 55367 |
UniProt ID | Q9HB75 |
Protein Families | Druggable Genome |
Protein Pathways | p53 signaling pathway |
Gene Summary | The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010] Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1. |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Deep Sequencing Reveals Direct Targets of Gammaherpesvirus-Induced mRNA Decay and Suggests That Multiple Mechanisms Govern Cellular Transcript Escape
,null,
PLoS ONE
,PubMed ID 21573023
[PIDD1]
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Other Versions
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RC203713 | PIDD (Myc-DDK-tagged)-Human p53-induced death domain protein (PIDD), transcript variant 3 |
CNY 6,544.00 |
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RC203713L1 | Lenti ORF clone of Human p53-induced death domain protein (PIDD), transcript variant 3, Myc-DDK-tagged |
CNY 8,944.00 |
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RC203713L2 | Lenti ORF clone of Human p53-induced death domain protein (PIDD), transcript variant 3, mGFP tagged |
CNY 9,030.00 |
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RC203713L3 | Lenti ORF clone of Human p53-induced death domain protein (PIDD), transcript variant 3, Myc-DDK-tagged |
CNY 9,030.00 |
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RC203713L4 | Lenti ORF clone of Human p53-induced death domain protein (PIDD), transcript variant 3, mGFP tagged |
CNY 9,030.00 |
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RG203713 | PIDD (tGFP-tagged) - Human p53-induced death domain protein (PIDD), transcript variant 3 |
CNY 8,144.00 |