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GDF 5 (GDF5) (NM_000557) Human Untagged Clone
CAT＃: SC125956
GDF5 (untagged)-Human growth differentiation factor 5 (GDF5)
CNY 3,736.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BDA1C; BMP-14; BMP14; CDMP1; DUPANS; LAP-4; LAP4; OS5; SYM1B; SYNS2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000557 edited
CGCTGCCACTGGTTAGCGATAATACTGGCAGCGCGACCGGTTTCTGAGGGTTGTTCACCT TGCTGCTCAGACGCTCCGAGAAGCTTCAGGCAGCATAACACTTACAGTAGAGACAGGGTT TCACCATGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGATCCACCTGCCTCGGCCT CCCAAGGTGCTGGGATTGCAGGCGTGAGCCACTGCGCCTGGCCGCAATTTACTTCATTGA ATCTCCAACAAGAGTCCTGTGAGCTGCTGACTGGAGACGGTGCACGTCTGGATACGAGAG CATTTCCACTATGGGACTGGATACAAACACACACCCGGCAGACTTCAAGAGTCTCAGACT GAGGAGAAAGCCTTTCCTTCTGCTGCTACTGCTGCTGCCGCTGCTTTTGAAAGTCCACTC CTTTCATGGTTTTTCCTGCCAAACCAGAGGCACCTTTGCTGCTGCCGCTGTTCTCTTTGG TGTCATTCAGCGGCTGGCCAGAGGATGAGACTCCCCAAACTCCTCACTTTCTTGCTTTGG TACCTGGCTTGGCTGGACCTGGAATTCATCTGCACTGTGTTGGGTGCCCCTGACTTGGGC CAGAGACCCCAGGGGACCAGGCCAGGATTGGCCAAAGCAGAGGCCAAGGAGAGGCCCCCC CTGGCCCGGAACGTCTTCAGGCCAGGGGGTCACAGCTATGGTGGGGGGGCCACCAATGCC AATGCCAGGGCAAAGGGAGGCACCGGGCAGACAGGAGGCCTGACACAGCCCAAGAAGGAT GAACCCAAAAAGCTGCCCCCCAGACCGGGCGGCCCTGAACCCAAGCCAGGACACCCTCCC CAAACAAGGCAGGCTACAGCCCGGACTGTGACCCCAAAAGGACAGCTTCCCGGAGGCAAG GCACCCCCAAAAGCAGGATCTGTCCCCAGCTCCTTCCTGCTGAAGAAGGCCAGGGAGCCC GGGCCCCCACGAGAGCCCAAGGAGCCGTTTCGCCCACCCCCCATCACACCCCACGAGTAC ATGCTCTCGCTGTACAGGACGCTGTCCGATGCTGACAGAAAGGGAGGCAACAGCAGCGTG AAGTTGGAGGCTGGCCTGGCCAACACCATCACCAGCTTTATTGACAAAGGGCAAGATGAC CGAGGTCCCGTGGTCAGGAAGCAGAGGTACGTGTTTGACATTAGTGCCCTGGAGAAGGAT GGGCTGCTGGGGGCCGAGCTGCGGATCTTGCGGAAGAAGCCCTCGGACACGGCCAAGCCA GCGGCCCCCGGAGGCGGGCGGGCTGCCCAGCTGAAGCTGTCCAGCTGCCCCAGCGGCCGG CAGCCGGCCTCCTTGCTGGATGTGCGCTCCGTGCCAGGCCTGGACGGATCTGGCTGGGAG GTGTTCGACATCTGGAAGCTCTTCCGAAACTTTAAGAACTCGGCCCAGCTGTGCCTGGAG CTGGAGGCCTGGGAACGGGGCAGGGCCGTGGACCTCCGTGGCCTGGGCTTCGACCGCGCC GCCCGGCAGGTCCACGAGAAGGCCCTGTTCCTGGTGTTTGGCCGCACCAAGAAACGGGAC CTGTTCTTTAATGAGATTAAGGCCCGCTCTGGCCAGGACGATAAGACCGTGTATGAGTAC CTGTTCAGCCAGCGGCGAAAACGGCGGGCCCCACTGGCCACTCGCCAGGGCAAGCGACCC AGCAAGAACCTTAAGGCTCGCTGCAGTCGGAAGGCACTGCATGTCAACTTCAAGGACATG GGCTGGGACGACTGGATCATCGCACCCCTTGAGTACGAGGCTTTCCACTGCGAGGGGCTG TGCGAGTTCCCATTGCGCTCCCACCTGGAGCCCACGAATCATGCAGTCATCCAGACCCTG ATGAACTCCATGGACCCCGAGTCCACACCACCCACCTGCTGTGTTCCCACGCGGCTGAGT CCCATCAGCATCCTCTTCATTGACTCTGCCAACAACGTGGTGTATAAGCAGTATGAGGAC ATGGTCGTGGAGTCGTGTGGCTGCAGGTAGCAGCACTGGCCCTCTGTCTTCCTGGGTGGC ACATCCCAAGAGCCCCTTCCTGCACTCCTGGAATCACAGAGGGGTCAGGAAGCTGTGGCA GGAGCATCTACACAGCTTGGGTGAAAGGGGATTCCAATAAGCTTGCTCGCTCTCTGAGTG TGACTTGGGCTAAAGGCCCCCTTTTATCCACAAGTTCCCCTGGCTGAGGATTGCTGCCCG TCTGCTGATGTGACCAGTGGCAGGCACAGGTCCAGGGAGACAGACTCTGAATGGGACTGA GTCCCAGGAAACAGTGCTTTCCGATGAGACTCAGCCCACCATTTCTCCTCACCTGGGCCT TCTCAGCCTCTGGACTCTCCTAAGCACCTCTCAGGAGAGCCACAGGTGCCACTGCCTCCT CAAATCACATTTGTGCCTGGTGACTTCCTGTCCCTGGGACAGTTGAGAAGCTGACTGGGC AAGAGTGGGAGAGAAGAGGAGAGGGCTTGGATAGAGTTGAGGAGTGTGAGGCTGTTAGAC TGTTAGATTTAAATGTATATTGATGAGATAAAAAGCAAAACTGTGCCTAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAA >OriGene 5' read for NM_000557 unedited
CATATTTGTATACGACTCACTATAGGCGGCCGCGTAATCAGATCTGGTACCGGTCCGGAA TTCCCGGGATCGCTGCCACTGGTTAGCGATAATACTGGCAGCGCGACCGGTTTCTGAGGG TTGTTCACCTTGCTGCTCAGACGCTCCGAGAAGCTTCAGGCAGCATAACACTTACAGTAG AGACAGGGTTTCACCATGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGATCCACCT GCCTCGGCCTCCCAAGGTGCTGGGATTGCAGGCGTGAGCCACTGCGCCTGGCCGCAATTT ACTTCATTGAATCTCCAACAAGAGTCCTGTGAGCTGCTGACTGGAGACGGTGCACGTCTG GATACGAGAGCATTTCCACTATGGGACTGGATACAAACACACACCCGGCAGACTTCAAGA GTCTCAGACTGAGGAGAAAGCCTTTCCTTCTGCTGCTACTGCTGCTGCCGCTGCTTTTGA AAGTCCACTCCTTTCATGGTTTTTCCTGCCAAACCAGAGGCACCTTTGCTGCTGCCGCTG TTCTCTTTGGTGTCATTCAGCGGCTGGCCAGAGGATGAGACTCCCCAAACTCCTCACTTT CTTGCTTTGGTACCTGGCTTGGCTGGACCTGGAATTCATCTGCACTGTGTTTGGGTGCCC CTGATTTGGGCCAAAGACCCCAGGGGACAGGCCAGGATTGGCCCAAACAGAGGCCAAGGA GAGGCCCCCCTGGGCCCGGAACGTCATCAGGCCGGGGGGTCAAACCTGGGGGGGGGGGCC ACCAAGCCAATGCCGGGGAAAGGGGGACCCGGGACAAACAGGGGCCTGACACCCCCAAAA GAGAGAACCAACAAGAGGCGCCCAAAAAGGGAGGGCCCGAAACCCAGCAGGAACCCCTCC CCTAACAAGGCGGGTACAAGCAAAGGAGAGGACCCAAAAGGAAGCTT |
| Restriction Sites | Please inquire |
| ACCN | NM_000557 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000557.2, NP_000548.1 |
| RefSeq Size | 2383 bp |
| RefSeq ORF | 1506 bp |
| Locus ID | 8200 |
| UniProt ID | P43026 |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207105 | GDF5 (Myc-DDK-tagged)-Human growth differentiation factor 5 (GDF5) |
CNY 3,728.00 |
|
| RC207105L1 | Lenti ORF clone of Human growth differentiation factor 5 (GDF5), Myc-DDK-tagged |
CNY 6,128.00 |
|
| RC207105L2 | Lenti ORF clone of Human growth differentiation factor 5 (GDF5), mGFP tagged |
CNY 5,890.00 |
|
| RC207105L3 | Lenti ORF clone of Human growth differentiation factor 5 (GDF5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207105L4 | Lenti ORF clone of Human growth differentiation factor 5 (GDF5), mGFP tagged |
CNY 5,890.00 |
|
| RG207105 | GDF5 (tGFP-tagged) - Human growth differentiation factor 5 (GDF5) |
CNY 5,320.00 |
