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ST14 (NM_021978) Human Untagged Clone
CAT＃: SC125523
ST14 (untagged)-Human suppression of tumorigenicity 14 (colon carcinoma) (ST14)
CNY 9,400.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARCI11; CAP3; HAI; MT-SP1; MTSP1; PRSS14; SNC19; TADG15; TMPRSS14 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125523 sequence for NM_021978 edited (data generated by NextGen Sequencing)
ATGGGGAGCGATCGGGCCCGCAAGGGCGGAGGGGGCCCGAAGGACTTCGGCGCGGGACTC AAGTACAACTCCCGGCACGAGAAAGTGAATGGCTTGGAGGAAGGCGTGGAGTTCCTGCCA GTCAACAACGTCAAGAAGGTGGAAAAGCATGGCCCGGGGCGCTGGGTGGTGCTGGCAGCC GTGCTGATCGGCCTCCTCTTGGTCTTGCTGGGGATCGGCTTCCTGGTGTGGCATTTGCAG TACCGGGACGTGCGTGTCCAGAAGGTCTTCAATGGCTACATGAGGATCACAAATGAGAAT TTTGTGGATGCCTACGAGAACTCCAACTCCACTGAGTTTGTAAGCCTGGCCAGCAAGGTG AAGGACGCGCTGAAGCTGCTGTACAGCGGAGTCCCATTCCTGGGCCCCTACCACAAGGAG TCGGCTGTGACGGCCTTCAGCGAGGGCAGCGTCATCGCCTACTACTGGTCTGAGTTCAGC ATCCCGCAGCACCTGGTGGAGGAGGCCGAGCGCGTCATGGCCGAGGAGCGCGTAGTCATG CTGCCCCCGCGGGCGCGCTCCCTGAAGTCCTTTGTGGTCACCTCAGTGGTGGCTTTCCCC ACGGACTCCAAAACAGTACAGAGGACCCAGGACAACAGCTGCAGCTTTGGCCTGCACGCC CGCGGTGTGGAGCTGATGCGCTTCACCACGCCCGGCTTCCCTGACAGCCCCTACCCCGCT CATGCCCGCTGCCAGTGGGCCCTGCGGGGGGACGCCGACTCAGTGCTGAGCCTCACCTTC CGCAGCTTTGACCTTGCGTCCTGCGACGAGCGCGGCAGCGACCTGGTGACGGTGTACAAC ACCCTGAGCCCCATGGAGCCCCACGCCCTGGTGCAGTTGTGTGGCACCTACCCTCCCTCC TACAACCTGACCTTCCACTCCTCCCAGAACGTCCTGCTCATCACACTGATAACCAACACT GAGCGGCGGCATCCCGGCTTTGAGGCCACCTTCTTCCAGCTGCCTAGGATGAGCAGCTGT GGAGGCCGCTTACGTAAAGCCCAGGGGACATTCAACAGCCCCTACTACCCAGGCCACTAC CCACCCAACATTGACTGCACATGGAACATTGAGGTGCCCAACAACCAGCATGTGAAGGTG CGCTTCAAATTCTTCTACCTGCTGGAGCCCGGCGTGCCTGCGGGCACCTGCCCCAAGGAC TACGTGGAGATCAATGGGGAGAAATACTGCGGAGAGAGGTCCCAGTTCGTCGTCACCAGC AACAGCAACAAGATCACAGTTCGCTTCCACTCAGATCAGTCCTACACCGACACCGGCTTC TTAGCTGAATACCTCTCCTACGACTCCAGTGACCCATGCCCGGGGCAGTTCACGTGCCGC ACGGGGCGGTGTATCCGGAAGGAGCTGCGCTGTGATGGCTGGGCCGACTGCACCGACCAC AGCGATGAGCTCAACTGCAGTTGCGACGCCGGCCACCAGTTCACGTGCAAGAACAAGTTC TGCAAGCCCCTCTTCTGGGTCTGCGACAGTGTGAACGACTGCGGAGACAACAGCGACGAG CAGGGGTGCAGTTGTCCGGCCCAGACCTTCAGGTGTTCCAATGGGAAGTGCCTCTCGAAA AGCCAGCAGTGCAATGGGAAGGACGACTGTGGGGACGGGTCCGACGAGGCCTCCTGCCCC AAGGTGAACGTCGTCACTTGTACCAAACACACCTACCGCTGCCTCAATGGGCTCTGCTTG AGCAAGGGCAACCCTGAGTGTGACGGGAAGGAGGACTGTAGCGACGGCTCAGATGAGAAG GACTGCGACTGTGGGCTGCGGTCATTCACGAGACAGGCTCGTGTTGTTGGGGGCACGGAT GCGGATGAGGGCGAGTGGCCCTGGCAGGTAAGCCTGCATGCTCTGGGCCAGGGCCACATC TGCGGTGCTTCCCTCATCTCTCCCAACTGGCTGGTCTCTGCCGCACACTGCTACATCGAT GACAGAGGATTCAGGTACTCAGACCCCACGCAGTGGACGGCCTTCCTGGGCTTGCACGAC CAGAGCCAGCGCAGCGCCCCTGGGGTGCAGGAGCGCAGGCTCAAGCGCATCATCTCCCAC CCCTTCTTCAATGACTTCACCTTCGACTATGACATCGCGCTGCTGGAGCTGGAGAAACCG GCAGAGTACAGCTCCATGGTGCGGCCCATCTGCCTGCCGGACGCCTCCCATGTCTTCCCT GCCGGCAAGGCCATCTGGGTCACGGGCTGGGGACACACCCAGTATGGAGGCACTGGCGCG CTGATCCTGCAAAAGGGTGAGATCCGCGTCATCAACCAGACCACCTGCGAGAACCTCCTG CCGCAGCAGATCACGCCGCGCATGATGTGCGTGGGCTTCCTCAGCGGCGGCGTGGACTCC TGCCAGGGTGATTCCGGGGGACCCCTGTCCAGCGTGGAGGCGGATGGGCGGATCTTCCAG GCCGGTGTGGTGAGCTGGGGAGACGGCTGCGCTCAGAGGAACAAGCCAGGCGTGTACACA AGGCTCCCTCTGTTTCGGGACTGGATCAAAGAGAACACTGGGGTATAG Clone variation with respect to NM_021978.3 1215 c=>t >OriGene 5' read for NM_021978 unedited
GGTGTTCGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGGAATTCGGACGAGCAGG GTACGACGCCTGTGAGACCCGCCAGCGGGCTCTGCGTCCATGGGGAGCGATCGGGCCCTC CTGGGCGGAGGGGGCCCGAATGACTTCCGCGCGGGACTCAAGCTCAACTACCGGCACGAG AAATTGAATGGCTTGTAGGAAGGCGTGTATTTCCTGCCAGTCAACAACGTCAAGAAGTGG AAAAGCATGGCCCGGGGCGCTAGGTGGTGCTGGCACCCGTGCTGATCGGCCTACTCTTGG TCTTGCTGGGGATCGGCTTTCTGGTGTGGCATTTGCAGTACCGGTACGTGCGTGTCCAGA AGGTCTTTAATGGCTACATGATGATCACAAATGAGAATTTTGTGGATGCCTACGAGAACT CCAACTCCACTGAGTTTGAAAGCCTGGCCAGCATGGTGAAGGACGCGCTGAAGCTGCTGT ACAGCGGAGTCCCATTCCTGGGCCCCTACTCACAAAGAGTCTGCTGTGACGGCCTTCAGC GAGTGCAGCGTCATCGCCTACTACTGGTCTGAGTTCAGCATCCCGCAGCACCTGGTGCAG GAGGACGATCGCGTCATGGCCCATGAGCGCGTAGTCATGCTGCCCCCGCGGTCGCGCTCC CTGAAGTCCTTTGTGGTCACCTCACTGGTGGCTATCCCCACTGACTTCAAAACAGTACAC AGGACCCATGACAACAGCTGCAGCTTTTGCCTGCACGCACGCGGTGTGCAGCTGATGCGC TTCACCACGCCAGGCTTGCCTGACAGNTCCTACCCGCTCATGCGCGCTAACANTGGGCCC TTGCGGGGGACGCCGACTCACTGCTGAGCCTCACCTTTCGCAGCTTTGACCTTGCGTCCT GCTACGAGCGCGGCTACGACCTGGAGACCGTGTACAACACCCTGATCCCCT >OriGene 3' read for NM_021978 unedited
ATCCGTAAGGCCATTGGGCGATGGTCAACTTGCCAGGNCACAGGGAAGAGCACTGGGGGN AGGGAGTCACAGGGCATGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGC AATCTAGAGTCGAGTTTTTTTGTTTTTTTTTTAAAAATAATAAAATGTTTTACTCATTTA CACAAATACACACACTGAAGTCCACCCTGGGATCTGGTAAAACAATTTCAGTCTCACACC CGTCTGTTTTCCAGGGTCCTCCGAGCCTGGGCTTCCTCAAGAGCGTGGCCCAAGGGCCCC ATAGCTCATATCCAGACTCCCCAACACCTTCACTGAAGAGGCCCCTAAGCTCCGTTCCCG GTGCTCCTTAAAGACAGGGGAGGCAGATATGCACAAACGCGCCTCGGCCCAGCTTGGGGC TGGCGGAGAGAGGCTGTGTCTTCAAACCTTTGCCCCCAGTTGGGTCAGTAAAACCACCAG TGTCCTCCCCTTTTACCTCCCAACTTCACTTTGGATGCTGATGAAGCGATAGGTTTTCTA GGCATATTTGGAGCCCTGGAGATTGATTTCACAGTGTATGTTCTGGGGGCGCTGGTGCAA TCAGCAGTCCAGTCTCCATCCTGCAAGCTGTGCACACTGGTGGTGGACGATGTGGTGGCA CCCGCAAGTGTACACATTTTGGGTAGGCCCCGGCCCCTATACCCCAGTGTTCTCTTTGAT CCAGTCCCGAAACAGAGGAGCCTTGTGTACACGCCTGGCTTGTTGCTCTGATCGCAGCCG TCTTCCCATCTGACCACACCGGACTGGAATATCCGGCCATCCGTCTCCACTCTGGACAGG GGTCCCCCCGAATCACGCTGGGCGGATACTAGCCCTGACGTGAGTCCCCT |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_021978 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | TrueClone. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021978.2, NP_068813.1 |
| RefSeq Size | 3269 bp |
| RefSeq ORF | 2568 bp |
| Locus ID | 6768 |
| UniProt ID | Q9Y5Y6 |
| Domains | CUB, Tryp_SPc, ldl_recept_a |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
,Drees, L;Königsmann, T;Jaspers, MHJ;Pflanz, R;Riedel, D;Schuh, R;,
PLoS Genet.
,PubMed ID 30601807
[ST14]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207136 | ST14 (Myc-DDK-tagged)-Human suppression of tumorigenicity 14 (colon carcinoma) (ST14) |
CNY 9,392.00 |
|
| RC207136L1 | Lenti ORF clone of Human suppression of tumorigenicity 14 (colon carcinoma) (ST14), Myc-DDK-tagged |
CNY 11,792.00 |
|
| RC207136L2 | Lenti ORF clone of Human suppression of tumorigenicity 14 (colon carcinoma) (ST14), mGFP tagged |
CNY 5,890.00 |
|
| RC207136L3 | Lenti ORF clone of Human suppression of tumorigenicity 14 (colon carcinoma) (ST14), Myc-DDK-tagged |
CNY 11,792.00 |
|
| RC207136L4 | Lenti ORF clone of Human suppression of tumorigenicity 14 (colon carcinoma) (ST14), mGFP tagged |
CNY 11,792.00 |
|
| RG207136 | ST14 (tGFP-tagged) - Human suppression of tumorigenicity 14 (colon carcinoma) (ST14) |
CNY 10,992.00 |
|
| SC323951 | ST14 (untagged)-Human suppression of tumorigenicity 14 (colon carcinoma) (ST14) |
CNY 9,400.00 |
