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P3H3 (NM_014262) Human Untagged Clone
CAT＃: SC125459
LEPREL2 (untagged)-Human leprecan-like 2 (LEPREL2)
CNY 5,400.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GRCB; HSU47926; LEPREL2 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_014262 edited
ATGCTCCGGCTCCTCCGGCCGCTGCTGCTACTGCTGCTGCTGCCTCCCCCGGGGTCCCCT GAGCCCCCCGGCCTGACCCAGCTGTCCCCGGGGGCGCCCCCGCAGGCCCCCGACTTGCTC TACGCTGACGGGCTGCGCGCCTACGCGGCCGGGGCTTGGGCGCCGGCCGTGGCGCTGCTG CGGGAGGCGCTGCGGAGCCAGGCGGCGCTGGGCCGGGTGCGGCTGGATTGCGGGGCGAGC TGCGCGGCCGATCCGGGCGCCGCGCTCCCCGCCGTGCTTCTCGGGGCCCCGGAGCCCGAC TCCGGGCCGGGACCCACGCAGGGGTCCTGGGAGCGACAGCTTCTCCGTGCAGCGCTCCGC CGCGCAGACTGCCTGACCCAGTGCGCAGCACGGAGGCTGGGCCCCGGGGGCGCGGCGCGG CTTCGCGTGGGGAGCGCGCTCCGGGACGCCTTCCGCCGTCGGGAGCCCTACAACTACCTG CAGAGGGCCTATTACCAGTTGAAGAAGCTGGATCTGGCAGCTGCGGCAGCACACACCTTC TTTGTAGCAAACCCCATGCACCTGCAGATGCGGGAGGACATGGCTAAGTACAGACGAATG TCGGGAGTTCGGCCCCAGAGCTTCCGGGACCTGGAGACGCCCCCACACTGGGCAGCCTAT GACACTGGCCTGGAGCTACTGGGGCGCCAGGAGGCAGGACTGGCACTGCCCAGGCTAGAG GAGGCTCTTCAGGGGAGCCTGGCCCAGATGGAGAGCTGCCGTGCTGACTGTGAGGGGCCT GAGGAGCAGCAGGGGGCTGAAGAAGAGGAGGATGGGGCTGCGAGCCAGGGGGGCCTCTAT GAGGCCATTGCAGGACACTGGATTCAGGTCCTGCAGTGCCGGCAACGCTGTGTGGGGGAA GCAGCCACACGCCCTGGTCGCAGCTTCCCTGTCCCAGACTTCCTTCCCAACCAGCTGAGG CGGCTACATGAGGCCCATGCTCAGGTGGGCAATCTGTCCCAGGCTATAGAAAATGTCCTG AGTGTCCTGCTCTTCTACCCGGAGGATGAGGCTGCCAAGAGGGCTCTGAACCAGTACCAG GCCCAGCTGGGAGAGCCGAGACCTGGCCTCGGACCCAGAGAGGACATCCAGCGCTTCATC CTCCGATCCCTGGGAGAGAAGAGGCAGCTCTACTATGCCATGGAGCACCTGGGGACCAGC TTCAAGGATCCTGACCCCTGGACCCCTGCAGCTCTCATCCCTGAGGCACTTAGAGAAAAG CTCAGAGAGGATCAAGAGAAGAGGCCTTGGGACCATGAGCCCGTGAAGCCAAAGCCCTTG ACCTACTGGAAGGATGTCCTTCTCCTGGAGGGTGTGACCTTGACCCAGGATTCCAGGCAG CTGAATGGGTCGGAGCGGGCGGTGTTGGATGGGCTGCTCACCCCAGCCGAGTGTGGGGTG CTGCTGCAGCTGGCTAAGGATGCAGCTGGGGCTGGAGCCAGGTCTGGCTATCGTGGTCGC CGCTCCCCTCACACCCCCCATGAACGCTTCGAGGGGCTCACGGTGCTTAAGGCTGCTCAG CTGGCCCGGGCTGGGACAGTGGGCAGTCAGGGTGCTAAGCTGCTTCTGGAGGTGAGCGAG CGGGTGCGGACCTTGACCCAGGCCTACTTCTCCCCGGAACGGCCCCTGCATCTGTCCTTC ACCCACCTGGTGTGCCGCAGCGCCATAGAAGGAGAGCAAGAGCAGCGCATGGACCTGAGT CACCCAGTGCACGCAGACAACTGCGTCCTGGACCCTGACACGGGAGAGTGCTGGCGGGAG CCCCCAGCCTACACCTATCGGGACTACAGCGGACTCCTCTACCTCAACGATGACTTCCAG GGTGGGGACCTGTTCTTCACGGAGCCCAACGCCCTCACTGTCACGGCTCGGGTGCGTCCT CGCTGTGGGCGCCTTGTGGCCTTCAGCTCCGGTGTCGAGAATCCCCATGGGGTGTGGGCC GTGACTCGGGGACGGCGCTGTGCCCTGGCACTGTGGCACACGTGGGCACCTGAGCACAGG GAGCAGGAGTGGACAGAAGCCAAAGAACTGCTGCAGGAGTCACAGGAGGAGGAGGAAGAG GAAGAGGAAGAAATGCCCAGCAAAGACCCTTCCCCAGAGCCCCCTAGCCGCAGGCACCAG AGGGTCCAAGACAAGACTGGAAGGGCACCTCGGGTTCGGGAGGAGCTGTGA >OriGene 5' read for NM_014262 unedited
CCCCCTATCCCCCGCCCGTTGACGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATA TAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGG CCGCGAATTCGGCACGAGGATCATGCTCCGGCTCCTACGGCCGCTGCTGCTACTGCTGAT GCTGGCTCCCCCGGGGTGCCCTGAGCCCCCCGGCCTGACCCAGCTGTGCCCGGGGGCGCC CCCGCAGGCCCCCGACTTGCTGTACGCTGACGGCCTGCTCGCCTACCCCGCCGGGGCTTG GGCGCCGGCCGTGGCGCTGCTGCGGGAGGCGCTGCGGACCCAGTCGGCGCTGGGCCGGCT GCGGCTGGATTGTGGGGCGAGCTGTGCACGCCGATCCGGGCGCCGCGCTCCCCGCCGTGC TTCTCGGGGCCCCGAAGGCCGACTCCGGGCCTGGCACCCACGCCAGGGGTCCTGGCAGCG ACAGCTTCTCCGTGCAGCGCTCCGCCGCGCAGACTGCCTGACCCAATGCGCAGCACACAG GCTGGGCCCCGGCGGCACGGCACGGCATTTCGTGGGGAGCGCGCTCCGGGACGCCTTCCG TCGTTGGGAGCCCTACAGCTACCTGCACAGGGGCTATTACCACGTGAAGAACTCTGATCT GTCCGCTGCGGCTGCACACACCTTCTGTGTAGCAAACCCCATGCACCTGCAGATGCGGGA GGACATGGCATAGTACAGACGAAGACTGGTAGTCTGTAGCAGAGCTTCTGGACCTGAAGA CGCTTCCACTGCGCAGCCTAGACACTGGCTGNACTACTGGGCGCCAGAGGCTGACTGGCC TGCCTAGCTGAGGAGCTCTCANGNGAGCTGGCCAGAGGAAGCTACGGCTGACGGAG >OriGene 3' read for NM_014262 unedited
NNNNAATTCACTTGNACCGCGCCGCATTCNANNGATCGGTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTGAGAGATCTTCACGACCTTTATTGCACAGACTGGGTAAAAAAGAACATGGT TATACCTCCCAACCCCAACATCCTCTTTATTTAAAGAATGAGCCTCCTCCCCTGCCATTT CCGTTCAGGAAAGCACAGGGTTCCCCATCTGTCCAGAAGCTACAAGTCCGGGAGCGGGGC CCCGTCCCAGCTCCCCAAGCCTGGTGAGCTCCAAGCTAGCCTGTGCACTGTCCTTTGAAT CCAGGCCCTTGTATGACCCCAAAATGGTGGGGGTGCAAGGTACAAGAAAAATTGCTGTTT TGAAAATGATGTCCCCCAGGGGCTTCCAGTGCGTCCTGACATCAAAATGGCCTTCCACAA ATCAAGTGGCCCCTTCCTCAAGGAGCTGGCTTAACCACTCATCTGCTCCTCACGGACCCC ATGTGCCCTTCCATTCTTGAATTGGACCCTCTGGTGCCAGCGGGTAAGGGGCTCGGGTTA AGGGCCTAAAGATGGCATTTTTTCCTATTCCGGTTCCGACTTCTCCAAGGAAACCTGCAA CAGTTCCTTGCCTTCTGTCCACTCCTGATCCCTGCGCTCATGTGCACACTTGTGCCTTAT TGCCCCGACACAGCGGCATTCTCCAGTGGGGTCCGCACCCCATGGGTTTCACGAATTCGA GCTGAAGGCACTAGCGCCCTCGCTTTGACTCTCCATACCTGACTTAAGGGCCTTGGCTCC ATAACGACTGTCCCCACCTGAAATCATCGTGGAGTTTAGTATGCGCTTGGTCACCAAGAG GTGAGCTGTGGCTACCCCCAAAACTTTTCGGTCCAGGTTCAAAAACCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014262 |
| Insert Size | 2850 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014262.2, NP_055077.2 |
| RefSeq Size | 2893 bp |
| RefSeq ORF | 2211 bp |
| Locus ID | 10536 |
| UniProt ID | Q8IVL6 |
| Domains | 2OG-FeII_Oxy, P4Hc |
| Gene Summary | The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor. [provided by RefSeq, Aug 2013] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer
,R Shah, P Smith, C Purdie, P Quinlan, L Baker, P Aman, A M Thompson, T Crook,
British Journal of Cancer 100, 1687-1696 (12 May 2009) doi:10.1038/sj.bjc.6605042 Genetics and Genomics
[P3H3]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215599 | LEPREL2 (Myc-DDK-tagged)-Human leprecan-like 2 (LEPREL2) |
CNY 5,392.00 |
|
| RC215599L3 | Lenti ORF clone of Human leprecan-like 2 (LEPREL2), Myc-DDK-tagged |
CNY 9,600.00 |
|
| RC215599L4 | Lenti ORF clone of Human leprecan-like 2 (LEPREL2), mGFP tagged |
CNY 9,600.00 |
|
| RG215599 | LEPREL2 (tGFP-tagged) - Human leprecan-like 2 (LEPREL2) |
CNY 8,460.00 |
