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BCAR3 (NM_003567) Human Untagged Clone
CAT＃: SC125362
BCAR3 (untagged)-Human breast cancer anti-estrogen resistance 3 (BCAR3)
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AND-34; MIG7; NSP2; SH2D3B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_003567, the custom clone sequence may differ by one or more nucleotides
ATGGCTGCAGGAAAATTTGCAAGCCTTCCCAGAAACATGCCGGTGAATCACCAGTTCCCCCTGGCCTCAT CCATGGACCTTCTGAGCAGCAGGTCCCCTCTCGCTGAGCATCGCCCAGATGCCTATCAAGATGTGTCTAT ACATGGCACCCTTCCACGGAAGAAAAAAGGTCCTCCTCCCATAAGGTCCTGTGATGACTTCAGTCACATG GGCACCCTCCCCCACTCCAAATCCCCACGGCAGAACTCGCCTGTGACCCAGGATGGCATCCAGGAGAGCC CATGGCAGGACCGGCACGGCGAAACCTTCACCTTCAGGGATCCACATCTTCTGGACCCAACTGTGGAATA TGTGAAGTTCTCCAAGGAGAGGCACATCATGGACAGGACCCCCGAGAAACTGAAGAAGGAGCTGGAGGAG GAGCTGCTCCTGAGCAGCGAGGACCTGCGCAGCCATGCCTGGTACCACGGCCGCATCCCCCGACAGGTGT CTGAAAACCTTGTGCAGCGAGATGGTGACTTCCTAGTTCGTGACTCTCTGTCCAGCCCTGGGAACTTTGT CCTGACCTGTCAGTGGAAGAACCTCGCTCAGCACTTCAAAATCAACCGGACAGTTCTGCGACTCAGCGAG GCCTACAGCCGCGTGCAGTACCAGTTCGAGATGGAGAGCTTCGACTCCATCCCCGGCCTGGTGCGCTGCT ACGTGGGCAACCGCCGGCCCATCTCCCAGCAGAGTGGCGCCATCATCTTCCAGCCCATCAACAGGACGGT GCCTCTGCGGTGCCTGGAGGAGCATTATGGCACCTCCCCAGGCCAGGCCCGGGAGGGCAGCCTCACCAAG GGAAGGCCGGATGTGGCCAAGAGGCTGAGCCTCACCATGGGTGGCGTCCAGGCCCGAGAGCAGAATTTGC CCAGGGGAAACCTCCTCAGAAACAAAGAAAAGAGTGGTAGCCAGCCCGCCTGCCTGGATCACATGCAGGA CAGAAGAGCCTTGTCCCTCAAAGCCCACCAGTCAGAGAGCTACCTGCCGATTGGCTGCAAGCTGCCACCT CAGTCCTCGGGTGTGGACACAAGCCCCTGCCCAAACTCACCTGTGTTCAGGACGGGAAGCGAGCCTGCCC TGAGCCCAGCAGTGGTTCGGAGGGTCTCCTCAGACGCCAGGGCTGGGGAGGCGCTGAGGGGATCAGACAG TCAACTGTGCCCTAAGCCCCCGCCTAAGCCCTGCAAGGTGCCGTTCCTCAAGGTTCCCTCGTCTCCCTCT GCCTGGCTCAACTCAGAGGCCAACTACTGTGAACTGAACCCAGCGTTTGCCACAGGCTGCGGCAGGGGAG CAAAGCTACCCTCATGTGCCCAGGGAAGCCACACAGAACTGCTCACAGCCAAGCAGAATGAGGCGCCAGG TCCCCGGAACTCTGGCGTCAACTACTTGATCCTTGATGATGATGACAGGGAAAGACCTTGGGAACCTGCG GCAGCTCAGATGGAGAAGGGGCAGTGGGACAAGGGCGAGTTTGTGACGCCCCTCCTGGAGACTGTCTCCT CCTTCAGGCCCAACGAGTTTGAGTCAAAGTTCCTTCCCCCTGAGAATAAGCCCCTGGAAACAGCAATGTT GAAACGTGCAAAAGAACTGTTCACCAACAACGACCCCAAGGTCATCGCCCAGCACGTACTGAGCATGGAC TGCAGGGTTGCTAGGATACTTGGAGTCTCTGAAGAGATGAGGAGGAACATGGGGGTGAGCTCAGGCCTGG AACTCATTACCTTGCCTCACGGACACCAGCTGCGCCTGGACATAATTGAAAGACACAACACAATGGCCAT CGGCATTGCAGTGGACATTCTGGGATGCACGGGCACTTTGGAGGACCGAGCGGCCACTCTGAGTAAGATC ATCCAGGTGGCGGTGGAACTGAAGGATTCCATGGGGGACCTCTATTCCTTCTCAGCTCTCATGAAAGCCC TGGAAATGCCACAGATCACAAGGTTAGAAAAGACGTGGACTGCTCTGCGGCACCAGTACACCCAAACTGC CATTCTCTATGAGAAACAGCTGAAGCCCTTCAGCAAACTCCTGCATGAAGGCAGAGAGTCCACATGTGTT CCCCCAAACAATGTATCAGTCCCACTGCTGATGCCGCTTGTGACGTTAATGGAGCGCCAGGCTGTGACTT TTGAAGGAACCGACATGTGGGAAAAAAACGACCAGAGCTGTGAAATCATGCTGAACCATTTGGCAACAGC GCGATTCATGGCCGAGGCTGCAGACAGCTACCGGATGAATGCTGAGAGGATCCTGGCAGGTTTTCAACCA GATGAAGAAATGAATGAAATCTGCAAGACTGAATTTCAAATGCGATTGCTATGGGGCAGCAAAGGTGCAC AAGTCAATCAGACAGAGAGATATGAGAAATTCAACCAGATTTTAACTGCCCTCTCGCGTAAATTGGAACC TCCTCCTGTAAAGCAGGCAGAGCTTTGA >OriGene 5' read for NM_003567 unedited
ATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCAAGCCTTCCCG AAACATGCCGGTGAATCACCAGTTCCCCCTGGCCTCATCCATGGACCTTCTGAGCAGCAG GTCCCCTCTCGCTGAGCATCGCCCAGATGCCTATCAAGATGTGTCTATACATGGCACCCT TCCACGGAAGAAAAAAGTCCTCCTCCCATAAGGTCCTGTGATGACTTCAGTCACATGGGC ACCCTCCCCCACTCCAAATCCCCACGGCAGAACTCGCCTGTGACCCAGGATGGCATCCAG GAGAGCCCATGGCAGGACCGGCACGGCGAAACCTTCACCTTCAGGGATCCACATCTTCTG GACCCAACTGTGGAATATGTGAAGTTCTCCAAGGAGAGGCACATCATGGACAGGACCCCC GAGAAACTGAAGAAGGAGCTGGAGGAGGAGCTGCTCCTGAGCAGCGAGGACCTGCGCAGC CATGCCTGGTACCACGGCCGCATCCCCCGACAGGTGTCTGAAAACCTTGTGCAGCGAGAT GGTGACTTCCTAGTTCGTGACTCTCTGTCCAGCCCTGGGAACTTTGTCCTGACCTGTCAG TGGAAGAACCTCGCTCAGCACTTCAAAATCAACCGGACAGTTCTGCGACTCAGCGAGGCC TACAGCCGCGTGCAGTACCAGTTCGAGATGGAGAGCTTCGACTCCATCCCCGGCCTGGTG CGCTGCTACGTGGGCAACCGCCGGGCCATCTCCCAGCAGAGTGGCGCCATCATCTTCCAG CCCATCAACAGGACNGTGCCTCTGCCGTGCCTGGAGGGAGCATATGGCACCTCCCCAGCC AGGCCCGGGAGGCCAGGCTCACCAGGGAAGGCCGNATGTGCCCAANAGCTGANCCTCACA TGGGGTGCGTC >OriGene 3' read for NM_003567 unedited
ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAACAAAAAAAGTATTTT CATTCATGAGTATTTACATTTTTCATATTTGTTTAAAGAATATCATATAACTGATACCTT CTGAAATGTTTCATGCTTTTAAACTCTTCTATTTACACTTATCTGACATGGAATTAAAAC TAAAATGGTCAAATACCATGATAATAGAAAGCAACCAGCCAACATAGCTAGGTCTTCTCT TAAATTTGCTGATCAACATTAGCAGTAGTTACCTTAATAATAAATTATTCATTTTAAAAT CAGTAGTAACTTTAGACAATTCATAAATAAGTGTGCTCTGTGCAATTTACACGTTTAATA TCCTGTGGATACTAAAAGCTCGTATATTGTCAGATTTGCACATTATTACTTTATCAAAAA CAGTAAGCTTTCCCAAAGATGAAGCTGGGGAAACTTGAAAAGATATTCTAAAGGTTCTCT GGAGAGTTATCAAAGCTCTGCCTGCTTTACAGGAGGAGGCTCCAATTACGCGAGAGGGCA CCTAAAACCCTGCAGACATCCTCATATCCTCTGCCCGACGACTTGTGCACCTTTCTGCCC ATCCCACTCCCTTTGAAATTAATTCTTGTAAATTCTCATAACTCTTTACTATCGCTCAAA CCCTCCCCCATCCTTTACATTCATCCGCCACTTTCTCCCCCCCCCCGCTAAATCTTCCAC TTAACAATGAAACACCTTAATCCTAAATACCCCCCACTCCGAACCATCTGCGTTCCGCTT CAGTCCCCTAACTTGATTCTTTAGCTTATTTACCCTATTCTATATCCCCCCTTCCTACAC CACCCTACCTCATCACCATACATACACTTACTACATACCCAATCTCGAGTACCCATCTCT CTTCTCCACTCACCACCTCCTCN |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_003567 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003567.3, NP_003558.1 |
| RefSeq Size | 3203 bp |
| RefSeq ORF | 2478 bp |
| Locus ID | 8412 |
| UniProt ID | O75815 |
| Domains | SH2, RasGEF |
| Protein Families | Druggable Genome |
| Gene Summary | Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein (isoform 1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207930 | BCAR3 (Myc-DDK-tagged)-Human breast cancer anti-estrogen resistance 3 (BCAR3) |
CNY 6,040.00 |
|
| RC207930L1 | Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), Myc-DDK-tagged |
CNY 8,440.00 |
|
| RC207930L2 | Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), mGFP tagged |
CNY 7,700.00 |
|
| RC207930L3 | Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC207930L4 | Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), mGFP tagged |
CNY 7,700.00 |
|
| RG207930 | BCAR3 (tGFP-tagged) - Human breast cancer anti-estrogen resistance 3 (BCAR3) |
CNY 7,640.00 |
|
| SC324095 | BCAR3 (untagged)-Human breast cancer anti-estrogen resistance 3 (BCAR3) |
CNY 6,048.00 |
