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DPP8 (NM_017743) Human Untagged Clone
CAT＃: SC125354
DPP8 (untagged)-Human dipeptidyl-peptidase 8 (DPP8), transcript variant 2
CNY 5,736.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DP8; DPRP-1; DPRP1; MST097; MSTP097; MSTP135; MSTP141 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_017743, the custom clone sequence may differ by one or more nucleotides
ATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATA TTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAA GCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCACATGATTTCATGTTTGTG AAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAG AAAATACACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAA GCCTCTTTTGGATCTTTTTCAGGCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGA GAAAGAAAACGCATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGT TTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAACCTTTAAG GCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGAC TGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCA CTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCT CCAAGAAGAATTTGATAGATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGT AAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTA TGTTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTT TAAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAA CCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGAGCTGGATGGACTCCTGAGGGAAAATATG CTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAGATAGTGTTGATCTCACCTGAATTATTTAT CCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTA ATTATCTATGAAGAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTC ACGAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATACAAAATTAC ATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCTCCAAGTGATTTCAAGTGT CCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATCC AAGTTGATGAAGTCAGAAGGCTGGTATATTTTGAAGGCACCAAAGACTCCCCTTTAGAGCATCACCTGTA CGTAGTCAGTTACGTAAATCCTGGAGAGGTGACAAGGCTGACTGACCGTGGCTACTCACATTCTTGCTGC ATCAGTCAGCACTGTGACTTCTTTATAAGTAAGTATAGTAACCAGAAGAATCCACACTGTGTGTCCCTTT ACAAGCTATCAAGTCCTGAAGATGACCCAACTTGCAAAACAAAGGAATTTTGGGCCACCATTTTGGATTC AGCAGGTCCTCTTCCTGACTATACTCCTCCAGAAATTTTCTCTTTTGAAAGTACTACTGGATTTACATTG TATGGGATGCTCTACAAGCCTCATGATCTACAGCCTGGAAAGAAATATCCTACTGTGCTGTTCATATATG GTGGTCCTCAGGTTGCTATTGCTGGGGCCCCAGTCACTCTGTGGATCTTCTATGATACAGGATACACGGA ACGTTATATGGGTCACCCTGACCAGAATGAACAGGGCTATTACTTAGGATCTGTGGCCATGCAAGCAGAA AAGTTCCCCTCTGAACCAAATCGTTTACTGCTCTTACATGGTTTCCTGGATGAGAATGTCCATTTTGCAC ATACCAGTATATTACTGAGTTTTTTAGTGAGGGCTGGAAAGCCATATGATTTACAGATCTATCCTCAGGA GAGACACAGCATAAGAGTTCCTGAATCGGGAGAACATTATGAACTGCATCTTTTGCACTACCTTCAAGAA AACCTTGGATCACGTATTGCTGCTCTAAAAGTGATATAA >OriGene 5' read for NM_017743 unedited
TGTTGTAAACGACTCCTATTAGGCGGCCGCGACATTCGCACGAGGGCCAAGGCCGCTGCT ACTGCCGCCGCTGCTTCTTAGTGCCGCGTTCGCCGCCTGGGTTGTCACCGGCGCCGCCGC CGAGGAAGCCACTGCAACCAGGACCGGAGTGGAGGCGGCGCAGCATGAAGCGGCGCAGGC CCGCTCCATAGCGCACGTCGGGACGGTCCGGGCGGGGCCGGGGGGAAGGAAAATGCAACA TGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTG AGGAGAATATTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATT CCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGG CTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAG ACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTG AAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGG ATCTTTTTCAGCAACACTGGACTATGGGAATGTATTCTCGAGAAGAAGAACTATTAANAG AAAAAAAACGCTTTGGAACAGTCGGAATTGGTTCTTACGATTATCACCAAGGAAGGGGAC ATTTCTTGTTTAAGCCGGGGGTGGAATTTATACCTAAAAAAGGGAGGGCCCCAGGGATTT ACCCACAACCCTTTAGGCCCATCTTAGGGAAACTAATTGGCCCACCTACGGGGGGGGCCA AAATTTTGCCCTGGGGTACCAAAAAGGATGGGTTTTATACTAAAAACCAAATTGGGAAAA AACAAAA >OriGene 3' read for NM_017743 unedited
CCATGTCATGGCATGGCACTCTCAGGNCCAGGAAAGCACTGGGGAAGGGTCACAGGGCAT GCCACCCGGGTATCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGT TTTTTTTTTTTTTTTTTTTTTAGAAATTCTTATGGTATTGCTGGGTCTCTCAGGAATATG TATCATTTGATTTTGAGCATGTGGGGTTAAGGTATTAGATTACTACCACAAACCGTAGAC CCCTGCATGGCACCACATTTATTTTCAGGAGTAGATGTTACATGGCAGGTATCAAAATGT GATGATCAATTCTGTGTTTTCTGTTGATTAAACCTCCTCATTTGGTTAAATAGCCAGTGT ATACCAGAGAGTTCTACACAGGTCAAAATTATATCACTTTTAGAGCAGCAATACGTGATC CAAGGTTTTCTTGAAGGTAGTGCAAAAGATGCAGTTCATAATGTTCTCCCGATTCAGGAA CTCTTATGCTGTGTCTCTCCTGAGGATAGATCTGTAAATCATATGGCTTTCCAGCCCTCA CTAAAAAACTCAGTAATATACTGGTATGTGCAAAATGGACATTCTCATCCAGGAAACCAT GTAAGAGCAGTAAACGATTTGGTTCAGAGGGGAACTTTTCTGCTTGCATGGCCACAGATC CTAAGTAATAGCCCTGTTCATTCTGGTCAGGGTGACCCATATAACGTTCCGTGTTTCCCG TAACCAAAAAGATCCCCAGGATGGCTGGGGCCCCCANCATTACCACCCCCGAAGATTTCT GACCTCTGCCTTTATGCCCTCAGGGAGAGGTTTTCCCCATAGGACCAGCCCGGGGTGCCC CACCNATCCACAGTTTTGACACCCNATCGGAGAGCTTTGTTTTGGGCCCCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017743 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017743.3, NP_060213.2 |
| RefSeq Size | 3796 bp |
| RefSeq ORF | 2349 bp |
| Locus ID | 54878 |
| UniProt ID | Q6V1X1 |
| Domains | DPPIV_N_term |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks two exons in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity
,Conrad Yap Edosada, Clifford Quan, Christian Wiesmann, Thuy Tran, Dan Sutherlin, Mark Reynolds, J. Michael Elliott, Helga Raab, Wayne Fairbrother, and Beni B. Wolf,
J. Biol. Chem. 2006 Mar 17;281(11):7437-44.
[DPP8]
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