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ADAMTS4 (NM_005099) Human Untagged Clone
CAT＃: SC125261
ADAMTS4 (untagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4)
CNY 6,136.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADAMTS-2; ADAMTS-4; ADMP-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_005099 edited
GGGAACCCACAGGGAGACCCACAGACACATATGCACGAGAGAGACAGAGGAGGAAAGAGA CAGAGACAAAGGCACAGCGGAAGAAGGCAGAGACAGGGCAGGCACAGAAGCGGCCCAGAC AGAGTCCTACAGAGGGAGAGGCCAGAGAAGCTGCAGAAGACACAGGCAGGGAGAGACAAA GATCCAGGAAAGGAGGGCTCAGGAGGAGAGTTTGGAGAAGCCAGACCCCTGGGCACCTCT CCCAAGCCCAAGGACTAAGTTTTCTCCATTTCCTTTAACGGTCCTCAGCCCTTCTGAAAA CTTTGCCTCTGACCTTGGCAGGAGTCCAAGCCCCCAGGCTACAGAGAGGAGCTTTCCAAA GCTAGGGTGTGGAGGACTTGGTGCCCTAGACGGCCTCAGTCCCTCCCAGCTGCAGTACCA GTGCCATGTCCCAGATAGGCTCGCATCCCGGGAGGGGCTTGGCAGGGCGCTGGCTGTGGG GAGCCCAACCCTGCCTCCTGCTCCCCATTGTGCCGCTCTCCTGGCTGGTGTGGCTGCTTC TGCTACTGCTGGCCTCTCTCCTGCCCTCAGCCCGGCTGGCCAGCCCCCTCCCCCGGGAGG AGGAGATCGTGTTTCCAGAGAAGCTCAACGGCAGCGTCCTGCCTGGCTCGGGCGCCCCTG CCAGGCTGTTGTGCCGCTTGCAGGCCTTTGGGGAGACGCTGCTACTAGAGCTGGAGCAGG ACTCCGGTGTGCAGGTCGAGGGGCTGACAGTGCAGTACCTGGGCCAGGCGCCTGAGCTGC TGGGTGGAGCAGAGCCTGGCACCTACCTGACTGGCACCATCAATGGAGATCCGGAGTCGG TGGCATCTCTGCACTGGGATGGGGGAGCCCTGTTAGGCGTGTTACAATATCGGGGGGCTG AACTCCACCTCCAGCCCCTGGAGGGAGGCACCCCTAACTCTGCTGGGGGACCTGGGGCTC ACATCCTACGCCGGAAGAGTCCTGCCAGCGGTCAAGGTCCCATGTGCAACGTCAAGGCTC CTCTTGGAAGCCCCAGCCCCAGACCCCGAAGAGCCAAGCGCTTTGCTTCACTGAGTAGAT TTGTGGAGACACTGGTGGTGGCAGATGACAAGATGGCCGCATTCCACGGTGCGGGGCTAA AGCGCTACCTGCTAACAGTGATGGCAGCAGCAGCCAAGGCCTTCAAGCACCCAAGCATCC GCAATCCTGTCAGCTTGGTGGTGACTCGGCTAGTGATCCTGGGGTCGGGCGAGGAGGGGC CCCAAGTGGGGCCCAGTGCTGCCCAGACCCTGCGCAGCTTCTGTGCCTGGCAGCGGGGCC TCAACACCCCTGAGAACTCGGACCCTGACCACTTTGACACAGCCATTCTGTTTACCCGTC AGGACCTGTGTGGAGTCTCCACTTGCGACACGCTGGGTATGGCTGATGTGGGCACCGTCT GTGACCCGGCTCGGAGCTGTGCCATTGTGGAGGATGATGGGCTCCAGTCAGCCTTCACTG CTGCTCATGAACTGGGTCATGTCTTCAACGTGCTCCATGACAACTCCAAGCCATGCATCA GTTTGAATGGGCCTTTGAGCACCTCTCGCCATGTCATGGCCCCTGTGATGGCTCATGTGG ATCCTGAGGAGCCCTGGTCCCCCTGCAGTGCCCGCTTCATCACTGACTTCCTGGACAATG GCTATGGGCACTGTCTCTTAGACAAACCAGAGGCTCCATTGCATCTGCCTGTGACTTTCC CTGGCAAGGACTATGATGCTGACCGCCAGTGCCAGCTGACCTTCGGGCCCGACTCACGCC ATTGTCCACAGCTGCCGCCGCCCTGTGCTGCCCTCTGGTGCTCTGGCCACCTCAATGGCC ATGCCATGTGCCAGACCAAACACTCGCCCTGGGCCGATGGCACACCCTGCGGGCCCGCAC AGGCCTGCATGGGTGGTCGCTGCCTCCACATGGACCAGCTCCAGGACTTCAATATTCCAC AGGCTGGTGGCTGGGGTCCTTGGGGACCATGGGGTGACTGCTCTCGGACCTGTGGGGGTG GTGTCCAGTTCTCCTCCCGAGACTGCACGAGGCCTGTCACCCGGAATGGTGGCAAGTACT GTGAGGGCCGCCGTGCCCGCTTCCGCTCCTGCAACACTGAGGACTGCCCAACTGGCTCAG CCCTGACCTTCCGCGAGGAGCAGTGTGCTGCCTACAACCACCGCACCGACCTCTTCAAGA GCTTCCCAGGGCCCATGGACTGGGTTCCTCGCTACACAGGCGTGGCCCCCCAGGACCAGT GCAAACTCACCTGCCAGGCCCAGGCACTGGGCTACTACTATGTGCTGGAGCCACGGGTGG TAGATGGGACCCCCTGTTCCCCGGACAGCTCCTCGGTCTGTGTCCAGGGCCGATGCATCC ATGCTGGCTGTGATCGCATCATTGGCTCCAAGAAGAAGTTTGACAAGTGCATGGTGTGCG GAGGGGACGGTTCTGGTTGCAGCAAGCAGTCAGGCTCCTTCAGGAAATTCAGGTACGGAT ACAACAATGTGGTCACTATCCCCGCGGGGGCCACCCACATTCTTGTCCGGCAGCAGGGAA ACCCTGGCCACCGGAGCATCTACTTGGCCCTGAAGCTGCCAGATGGCTCCTATGCCCTCA ATGGTGAATACACGCTGATGCCCTCCCCCACAGATGTGGTACTGCCTGGGGCAGTCAGCT TGCGCTACAGCGGGGCCACTGCAGCCTCAGAGACACTGTCAGGCCATGGGCCACTGGCCC AGCCTTTGACACTGCAAGTCCTAGTGGCTGGCAACCCCCAGGACACACGCCTCCGATACA GCTTCTTCGTGCCCCGGCCGACCCCTTCAACGCCACGCCCCACTCCCCAGGACTGGCTGC ACCGAAGAGCACAGATTCTGGAGATCCTTCGGCGGCGCCCCTGGGCGGGCAGGAAATAAC CTCACTATCCCGGCTGCCCTTTCTGGGCACCGGGGCCTCGGACTTAGCTGGGAGAAAGAG AGAGCTTCTGTTGCTGCCTCATGCTAAGACTCAGTGGGGAGGGGCTGTGGGCGTGAGACC TGCCCCTCCTCTCTGCCCTAATGCGCAGGCTGGCCCTGCCCTGGTTTCCTGCCCTGGGAG GCAGTGATGGGTTAGTGGATGGAAGGGGCTGACAGACAGCCCTCCATCTAAACTGCCCCC TCTGCCCTGCGGGTCACAGGAGGGAGGGGGAAGGCAGGGAGGGCCTGGGCCCCAGTTGTA TTTATTTAGTATTTATTCACTTTTATTTAGCACCAGGGAAGGGGACAAGGACTAGGGTCC TGGGGAACCTGACCCCTGACCCCTCATAGCCCTCACCGTGGGGCTAGGAAATCCAGGGTG GTGGTGATAGGTATAAGTGGTGTGTGTATGCGTGTGTGTGTGTGTGAAAATGTGTGTGTG CTTATGTATGAGGTACAACCTGTTCTGCTTTCCTCTTCCTGAATTTTATTTTTTGGGAAA AGAAAAGTCAAGGGTAGGGTGGGCCTTCAGGGAGTGAGGGATTATCTTTTTTTTTTTTTT CTTTCTTTCTTTCTTTTTTTTTTTTGAGACAGAATCTCGCTCTGTCGCCCAGGCTGGAGT GCAATGGCACAATCTCGGCTCACTGCATCCTCCGCCTCCCGGGTTCAAGTGATTCTCATG CCTCAGCCTCCTGAGTAGCTGGGATTACAGGCTCCTGCCACCACGCCCGGCTAATTTTTG TTTTGTTTTGTTTGGAGACAGAGTCTCGCTATTGTCACCAGGGCTGGAATGATTTCAGCT CACTGCAACCTTCGCCACCTGGGTTCCAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCT GAGATTATAGGCACCTACCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGG TTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTTAGGTGATCCACTCGCCTTC ATCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCTGGCCACGCCCAACTAAT TTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGCTCTTGAACTCCT GACCTCAGGTAATCGACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCA CCACGCCCGGTACATATTTTTTAAATTGAATTCTACTATTTATGTGATCCTTTTGGAGTC AGACAGATGTGGTTGCATCCTAACTCCATGTCTCTGAGCATTAGATTTCTCATTTGCCAA TAATAATACCTCCCTTAGAAGTTTGTTGTGAGGATTAAATAATGTAAATAAAGAACTAGC ATAACAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005099 |
| Insert Size | 4400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain 4 SNPs compared with NM_005099.3. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005099.3, NP_005090.2 |
| RefSeq Size | 4342 bp |
| RefSeq ORF | 2514 bp |
| Locus ID | 9507 |
| UniProt ID | O75173 |
| Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
| Gene Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209226 | ADAMTS4 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4) |
CNY 6,128.00 |
|
| RC209226L1 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4), Myc-DDK-tagged |
CNY 8,528.00 |
|
| RC209226L2 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4), mGFP tagged |
CNY 9,030.00 |
|
| RC209226L3 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC209226L4 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4), mGFP tagged |
CNY 9,030.00 |
|
| RG209226 | ADAMTS4 (tGFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4) |
CNY 7,728.00 |
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