KRIT1 (NM_194455) Human Untagged Clone
CAT#: SC124507
KRIT1 (untagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 4
CNY 7,220.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CAM; CCM1 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_194455, the custom clone sequence may differ by one or more nucleotides
ATGGGAAATCCAGAAAACATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTCA ATTCTCGGGAATACAGAGCTAAGTCATATGAAATTTTGTTGCATGAAGTTCCCATTGAAGGACAGAAAAA AAAGAGAAAGAAAGTTTTATTGGAAACGAAACTTCAAGGCAACAGTGAAATAACACAAGGCATATTGGAT TACGTAGTAGAAACCACCAAACCAATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACGAGTTGTACTAA TGAAAAAATTTCCTCTGGATGGAGAGAAGATGGGCAGAGAAGCATCATTATTTATTGTTCCATCAGTTGT CAAAGATAATACTAAATACACATATACCCCAGGATGCCCAATTTTTTACTGCTTACAAGATATTATGCGA GTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGTTAATAGCCTTGGATAAGTGGT TAGATGAACGTCATGCACAATCTCACTTTATTCCAGCTTTATTCCGACCTTCTCCTCTTGAGCGGATAAA AACTAATGTCATAAATCCTGCATATGCTACTGAATCAGGTCAGACAGAAAACTCACTACATATGGGCTAT AGTGCACTAGAAATAAAGAGTAAAATGTTAGCCCTAGAGAAAGCAGATACCTGTATTTACAACCCTTTGT TTGGATCAGATCTTCAGTATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAGC TCCAGACTACTCAAAAATCCAAATACCTAAACAGGAAAAATGGCAGAGAAGCATGAGCAGTGTCACAGAA GACAAGGAACGACAGTGGGTAGATGATTTTCCTCTCCACCGAAGCGCCTGTGAAGGAGATTCAGAATTAC TAAGCCGTCTTCTCAGTGAAAGATTTTCAGTCAACCAGTTAGATAGTGACCACTGGGCACCCATTCATTA TGCATGCTGGTATGGAAAAGTTGAGGCCACTCGCATATTGTTAGAGAAAGGAAAGTGCAATCCAAACCTT TTAAATGGACAACTTAGTTCTCCTCTTCATTTTGCTGCTGGAGGAGGACATGCTGAAATAGTACAGATTC TCCTAAACCACCCAGAAACGGATAGACATATAACAGACCAACAAGGAAGATCTCCATTAAATATTTGTGA AGAAAACAAACAAAACAACTGGGAAGAAGCTGCAAAATTGTTGAAGGAAGCAATTAACAAACCATATGAA AAAGTTCGAATATACAGAATGGATGGGTCATATCGTTCTGTTGAATTGAAGCATGGAAATAATACCACAG TGCAGCAGATAATGGAAGGAATGCGTCTCTCTCAAGAAACTCAGCAATATTTCACTATATGGATTTGTTC AGAAAACCTCAGCCTTCAACTCAAACCATATCATAAACCCTTGCAACATGTTCGTGACTGGCCAGAAATA CTTGCTGAATTGACTAATCTGGATCCTCAAAGGGAAACACCTCAGCTTTTTCTAAGAAGAGATGTGAGAC TTCCCTTGGAAGTTGAAAAACAGATTGAAGACCCACTAGCTATTCTTATTCTCTTTGATGAAGCCAGATA TAATTTATTGAAGGGCTTTTATACAGCTCCTGATGCTAAGCTGATAACATTGGCAAGTCTGCTTTTGCAA ATAGTCTATGGAAATTATGAGAGTAAAAAACACAAGCAAGGTTTCCTAAATGAAGAAAATCTAAAATCCA TCGTACCTGTTACCAAACTGAAAAGTAAGGCACCTCACTGGACAAATCGCATACTTCATGAATACAAGAA TCTCAGTACAAGTGAAGGTGTCAGTAAAGAAATGCATCACCTTCAGCGCATGTTCTTACAGAATTGCTGG GAAATTCCTACTTATGGAGCAGCATTTTTCACAGGACAGATATTTACAAAGGCAAGCCCCAGCAATCATA AAGTCATCCCTGTGTATGTAGGAGTGAATATAAAAGGACTTCATCTCCTCAACATGGAAACTAAGGCTTT ACTCATCAGTCTTAAGTATGGTTGTTTTATGTGGCAATTGGGAGATACTGATACTTGTTTTCAGATCCAT AGCATGGAAAATAAAATGAGCTTTATAGTACATACAAAACAGGCTGGTCTCGTGGTAAAACTGTTAATGA AGCTAAATGGACAGTTAATGCCCACTGAAAGAAATTCATGA >OriGene 5' read for NM_194455 unedited
TTATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGATTTGTAAACGTTTATTAT CTTGAAGTCATTGTTAATCTGTGGTGAAAAGTAATTGCTAAATAGAAATTCTGAGAAGAA AAAGGCCTCATCCTTTTCACATGATGTAGGAAGGTCTGTTGCATGAGCAATGGGAAATCC AGAAAACATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTCAA TTCTCGGGAATACAGAGCTAAGTCATATGAAATTTTGTTGCATGAAGTTCCCATTGAAGG ACAGAAAAAAAAGAGAAAGAAAGTTTTATTGGAAACGAAACTTCAAGGCAACAGTGAAAT AACACAAGGCATATTGGATTACGTAGTAGAAACCACCAAACCAATTTCTCCTGCAAACCA GGGTATCAGAGGAAAACGAGTTGTACTAATGAAAAAATTTCCTCTGGATGGAGAGAAGAT GGGCAGAGAAGCATCATTATTTATTGTTCCATCAGTTGTCAAAGATAATACTAAATACAC ATATACCCCAGGATGCCCAATTTTTTTACTGCTTACAAGATATTATGCGAGTCTGTAGTG AATCCAGTACTCATTNTGCTACACTTACAGNCAGGATGTTAATAGCCTTGGATAAGTGGT TAGATGAACGTCATGCACAATCTCACTTTATTCCAGCTNTATTCCGACCTTCTNCTCTTG AGCGGGATAAAACTAATGTCATAAATCCTGCATATGCTACTGAATCANGTCAGACAGAAN ACTCACTACATATGGGNCTATAGTGCACTAGAAATAAGAGTAAATGNTAGCCCTAGAGAA GCAGATACCTGTATTACAACCTTTGNTNGATCAGATCTCAGATACAATCGGTAGATAAGT GGTATAAATCTACTTGGNCTAGAGCTCAACTCTCAAATCCATACCTACAGAAAATGCNAN AACTGACNTGTCAAAAAANGACAACTGGNNTAAGATTTNCTTNACGANCGCTGNANGAAA TCAATNCTAGCGCTTTCANGAAGATTTCGCACGNTAAATGCCCTGGCCCATCTTGCTCTG TATGAAGTAG |
Restriction Sites | NotI-NotI |
ACCN | NM_194455 |
Insert Size | 4700 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_194455.1, NP_919437.1 |
RefSeq Size | 4997 bp |
RefSeq ORF | 2211 bp |
Locus ID | 889 |
UniProt ID | O00522 |
Protein Families | Druggable Genome |
Gene Summary | This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009] Transcript Variant: This variant (4) has 2 alternate exons in the 5' UTR, as compared to variant 1. Variants 1-4 encode the same isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC220516 | KRIT1 (Myc-DDK-tagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 4 |
CNY 5,392.00 |
|
RC220516L3 | Lenti-ORF clone of KRIT1 (Myc-DDK-tagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 4 |
CNY 5,890.00 |
|
RC220516L4 | Lenti-ORF clone of KRIT1 (mGFP-tagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 4 |
CNY 5,890.00 |
|
RG220516 | KRIT1 (tGFP-tagged) - Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 4 |
CNY 4,370.00 |