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TIGIT (NM_173799) Human Untagged Clone
CAT＃: SC124474
TIGIT (untagged)-Human T cell immunoreceptor with Ig and ITIM domains (TIGIT)
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | VSIG9; VSTM3; WUCAM |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124474 sequence for NM_173799 edited (data generated by NextGen Sequencing)
ATGCGCTGGTGTCTCCTCCTGATCTGGGCCCAGGGGCTGAGGCAGGCTCCCCTCGCCTCA GGAATGATGACAGGCACAATAGAAACAACGGGGAACATTTCTGCAGAGAAAGGTGGCTCT ATCATCTTACAATGTCACCTCTCCTCCACCACGGCACAAGTGACCCAGGTCAACTGGGAG CAGCAGGACCAGCTTCTGGCCATTTGTAATGCTGACTTGGGGTGGCACATCTCCCCATCC TTCAAGGATCGAGTGGCCCCAGGTCCCGGCCTGGGCCTCACCCTCCAGTCGCTGACCGTG AACGATACAGGGGAGTACTTCTGCATCTATCACACCTACCCTGATGGGACGTACACTGGG AGAATCTTCCTGGAGGTCCTAGAAAGCTCAGTGGCTGAGCACGGTGCCAGGTTCCAGATT CCATTGCTTGGAGCCATGGCCGCGACGCTGGTGGTCATCTGCACAGCAGTCATCGTGGTG GTCGCGTTGACTAGAAAGAAGAAAGCCCTCAGAATCCATTCTGTGGAAGGTGACCTCAGG AGAAAATCAGCTGGACAGGAGGAATGGAGCCCCAGTGCTCCCTCACCCCCAGGAAGCTGT GTCCAGGCAGAAGCTGCACCTGCTGGGCTCTGTGGAGAGCAGCGGGGAGAGGACTGTGCC GAGCTGCATGACTACTTCAATGTCCTGAGTTACAGAAGCCTGGGTAACTGCAGCTTCTTC ACAGAGACTGGTTAG Clone variation with respect to NM_173799.3 >OriGene 5' read for NM_173799 unedited
TGTAATACGACCTCACTATAGGGCGGCCGCGATTCGGCACGAGGCAGAAGCATGCGCTGG TGTCTCCTCCTGATCTGGGCCCAGGGGCTGAGGCAGGCTCCCCTCGCCTCAGGAATGATG ACAGGCACAATAGAAACAACGGGGAACATTTCTGCAGAGAAAGGTGGCTCTATCATCTTA CAATGTCACCTCTCCTCCACCACGGCACAAGTGACCCAGGTCAACTGGGAGCAGCAGGAC CAGCTTCTGGCCATTTGTAATGCTGACTTGGGGTGGCACATCTCCCCATCCTTCAAGGAT CGAGTGGCCCCAGGTCCCGGCCTGGGCCTCACCCTCCAGTCGCTGACCGTGAACGATACA GGGGAGTACTTCTGCATCTATCACACCTACCCTGATGGGACGTACACTGGGAGAATCTTC CTGGAGGTCCTANAAAGCTCAGTGGCTGAGCACGGTGCCAGGTTCCAGATTCCATTGCTT GGAGCCATGGCCGCGACGCTGGTGGTCATCTGCACAGCAGTCATCGTGGTGGTCGCGTTG ACTAAAAAGAAGAAAGCCCTCAGAATCCATTCTGTGGAAGGTGACCTCAGGAGAAAATAN CTNGACAGGAGGAATGGAGCCCCCANTGCTCCCTTACCCCACAGAAACTGGGTCCAAGCA AAACCTGCACCTGCTGGGCTCTCTGGGAAAAACACCGGGAAAAGGAATGGGCCCCACCCC ACAGAATAACTTAAAGGGCCCGGATAAACAAAACCGGGGGAAAGGGGGTTTTTTCAAAAA AAGGGTTAACACCAGGGCGTTTTGTGAGAAAACACTTCTTTTTTCTTTTTTAAAAAAAAT AAAAAAAGGGGCCTTCCCCCACTCNNNNTGGGTGGGTGGGGTTATTTTNNNNNNNGGGNN NAAAAAAAAAAAAAAAAACCCTCTCTCCTTCT >OriGene 3' genomic read for NM_173799 unedited
TGGCCATTGGCATGGCACTTCCAGGNCCAGGNAAAGCACTGGGGNAGGGTCACAGGGCAT GCCACCCGGGCTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAGGGTAATATTTTATTTCACCCA ATACATCCAAAATATTATCATTTTTGACACACAATATACCAAAACTACTGAAATAGTATT CTTATTATTCATATTAAATCCCCAAAATCTAGTGTGATTTTATGCTTATACCAATTATAA CAGCACATCTTGATTTAAACTAACCCCATCTTAAGTGGTTGATGGCCACATGTGGAAAGT GGCTACGTGGTGGATAGCGCATGTCTCCAGGAATCCAACTATGAAATGGTCTTCTCTGGT TCTCAAAGGAAAATCTAGTTCAGTGAGTTCTATTTAAAAAAATTTTTTTCAAATTGAATC CCATTTCAGTAACCTGACCCATTTCTAACATCTATAGGCCCTTTTGTATTTTATCACCAT CCCAATAGTGTTTATAAATGTTTCCCAATTACCATAATTATGTTAAATAACACCCAACTC TCAATCCAACCTCTGCCGAATATACACCTCCTCCAAATCAAAACACTACCCCCTTTTCGT CATTACTTTTTAGTTTACTTCCCTTTTGGGAATTGTGGTCCATTTCCCCCGGGTTTGCAC CTNTTTTTGCNGGAAAATGGCTGGAACCGCCCCAGCCAAAAAACCACTTTTTTCCCGTCC CCNAACCTTTTCCCCCNGGGGTCTGGGGCCCTGGGCCNNTTTNNNTTTCTTCTCCCCCGG GNNCCCCTTTTGGGGNNNNNGGGNNNNNNGTNTNNCNNNNNANCCCCCCGGGAAAAAATT TTATATTAAGCTAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_173799 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_173799.2, NP_776160.1 |
| RefSeq Size | 2139 bp |
| RefSeq ORF | 735 bp |
| Locus ID | 201633 |
| UniProt ID | Q495A1 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Increased expression of TIGIT on CD4(+) T cells ameliorates immune-mediated bone marrow failure of aplastic anemia
,Zhang, T;Wang, J;Zhou, X;Liang, R;Bai, Q;Yang, L;Gu, H;Gao, G;Dong, B;Zhu, H;Chen, X;,
J. Cell. Biochem.
,PubMed ID 24905442
[TIGIT]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221447 | TIGIT (Myc-DDK-tagged)-Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) |
CNY 3,600.00 |
|
| RC221447L1 | Lenti ORF clone of Human T cell immunoreceptor with Ig and ITIM domains (TIGIT), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC221447L2 | Lenti ORF clone of Human T cell immunoreceptor with Ig and ITIM domains (TIGIT), mGFP tagged |
CNY 5,890.00 |
|
| RC221447L3 | Lenti ORF clone of Human T cell immunoreceptor with Ig and ITIM domains (TIGIT), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC221447L4 | Lenti ORF clone of Human T cell immunoreceptor with Ig and ITIM domains (TIGIT), mGFP tagged |
CNY 6,000.00 |
|
| RG221447 | TIGIT (tGFP-tagged) - Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) |
CNY 5,200.00 |
