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SOCS6 (NM_004232) Human Untagged Clone
CAT＃: SC124420
SOCS6 (untagged)-Human suppressor of cytokine signaling 6 (SOCS6)
CNY 3,992.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIS-4; CIS4; HSPC060; SOCS-4; SOCS-6; SOCS4; SSI4; STAI4; STATI4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124420 sequence for NM_004232 edited (data generated by NextGen Sequencing)
ATGAAGAAAATTAGTCTTAAAACCTTACGGAAATCTTTTAACTTGAATAAAAGTAAAGAA GAAACTGATTTCATGGTAGTACAACAACCATCGCTAGCCAGTGACTTTGGAAAAGATGAT TCCTTATTTGGTAGCTGCTATGGTAAAGATATGGCCAGCTGCGATATCAACGGTGAAGAT GAAAAAGGCGGAAAAAACAGATCAAAAAGCGAGAGCCTGATGGGTACGCTAAAAAGGCGG CTTTCTGCAAAACAGAAGTCAAAAGGCAAGGCGGGCACACCCTCTGGGAGCTCTGCCGAC GAGGACACCTTCTCCTCCTCCTCAGCACCCATAGTCTTTAAAGACGTGAGAGCTCAGAGG CCGATAAGGTCCACGTCGCTCCGCAGCCATCACTACAGTCCCGCGCCGTGGCCTCTGCGG CCCACAAACTCCGAGGAGACCTGCATCAAGATGGAGGTGAGAGTCAAGGCCTTGGTTCAC TCTTCCAGCCCGAGTCCAGCCCTGAATGGCGTCCGGAAGGATTTCCACGACCTCCAGTCT GAGACCACGTGCCAGGAGCAAGCCAATTCACTGAAGAGCTCGGCTTCTCATAATGGAGAC CTGCATCTTCACCTGGATGAACATGTGCCTGTCGTTATTGGACTTATGCCTCAGGACTAC ATTCAGTATACTGTGCCTTTAGATGAGGGGATGTATCCTTTGGAAGGATCACGGAGCTAT TGTCTGGACAGCTCTTCTCCCATGGAAGTCTCTGCGGTTCCTCCTCAAGTGGGAGGGCGC GCTTTCCCCGAGGATGAGAGTCAGGTAGACCAGGACCTAGTTGTCGCCCCAGAGATCTTC GTGGATCAGTCCGTGAATGGCTTGTTGATTGGCACCACGGGAGTCATGTTGCAGAGCCCG AGAGCGGGTCACGATGATGTCCCTCCACTCTCACCATTGCTACCTCCAATGCAGAATAAT CAAATCCAAAGGAACTTCAGTGGACTCACTGGCACAGAAGCCCACGTGGCTGAAAGTATG CGCTGTCATTTGAATTTTGATCCGAACTCTGCTCCTGGGGTTGCAAGAGTTTATGACTCA GTGCAAAGTAGTGGTCCCATGGTTGTGACAAGCCTTACAGAGGAGCTGAAAAAACTTGCA AAGCAAGGATGGTACTGGGGACCAATCACACGTTGGGAGGCAGAAGGGAAGCTAGCAAAC GTGCCAGATGGTTCTTTTCTTGTTCGGGACAGTTCTGACGACCGTTACCTTTTAAGCTTG AGCTTTCGCTCCCATGGTAAAACACTTCACACTAGAATTGAGCACTCAAATGGTAGGTTT AGCTTTTATGAACAGCCAGATGTGGAAGGACATACGTCCATAGTTGATCTAATTGAGCAT TCAATCAGGGACTCTGAAAATGGAGCTTTTTGTTATTCAAGGTCTCGGCTGCCTGGATCT GCAACTTACCCCGTCAGACTGACCAACCCAGTGTCCCGGTTCATGCAGGTGCGCTCGTTG CAGTACCTGTGTCGTTTTGTTATACGTCAGTATACCAGAATAGACTTAATTCAGAAACTG CCTTTGCCAAACAAAATGAAGGATTATTTACAGGAGAAGCACTACTGA Clone variation with respect to NM_004232.3 >OriGene 5' read for NM_004232 unedited
GAATAGGTAATACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGCGCTGGGC GAGGAAGCGGAGCCGGGCCGCCTCCGGAAAAGGCTCCAAAGGTTAAATGAAGCAGGAAAA ATACATAGATGCAGCCTTGCAGCCTCTCACGATGTTTGGGGATAATATTCCAGATAGAAA TATTGATCCCTTGGATTAGGTAACTAGTCATAATGAAGAAAATTAGTCTTAAAACCTTAC GGAAATCTTTTAACTTGAATAAAAGTAAAGAAGAAACTGATTTCATGGTAGTACAACAAC CATCGCTAGCCAGTGACTTTGGAAAAGATGATTCCTTATTTGGTAGCTGCTATGGTAAAG ATATGGCCAGCTGCGATATCAACGGTGAAGATGAAAAAGGCGGAAAAAACAGATCAAAAA GCGAGAGCCTGATGGGTACGCTAAAAAGGCGGCTTTCTGCAAAACAGAAGTCAAAAGGCA AGGCGGGCACACCCTCTGGGAGCTCTGCCGACGAGGACACCTTCTCCTNCTCCTCAGCAC CCATAGTCTTTAAAGACGTGAGAGCTCAGAGGCCGATAAGGTCCACGTCGCTCCGCAGAC ATCACTACAGTCCCGCGCCGTGGCCTCTGCGGCCCACAAACTCCGAGGAGACCTGCATCA AGATGGAGGTGAGAGTCAAGGCCCTTGTTCACTCTTNCAGCCCGAGTCCAGCCCTGAATG GCGACTCGGAAGGATTNCACGACCTCCAGTCTGAGACCACGTGCCCGGAGCAAGCCAATN CACTTGAGAGCTCGGCTTCTCATTATGGAGACCTGCATCTTACCTGGATGACATGTGCCT GTCGTTATTGGACTATGCCTTAAGACTACATTTATATACTGTGCCTTAGATGAAGGGAGG ATCCTTTGAAGGACACCGAGCTTTGTCTGGACGCTCTTCTCCATGGAAGTTCTTCGGTTC CTCTCCAGAGGAAGGGCCCTTTCCCCAAGAGAGAATAAGTAAAC >OriGene 3' read for NM_004232 unedited
GACCGCGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTGAACGAAATTTTTTA TTTACACACTGTATCTAGAAGCAGATACATAAATTCTTATACAATTAATTTCCAAAAATG TGCAAGAAATTACTATAATTTGTTTACAAACCAAAACACGTATTAAAATCAATGGACTTT GGATAATTCATTCTGTGGTGTTCTCAGTACAAATGGTACACACCTGATTTGAAACATACA GAAAAAGTGTAAACTACCGCAATCTGAATTGCAAGTATTAATTTCATGGCACTCCAACGA CTATGAAATTTCTTTCACCCAACATGTAAATACTTGTTACAAAATTCTATAAGAATTTTT CATAATCTCTGGATGTAGAGTTTGGATCACTTTTCAGAAACAGCAACTACACACTTCGCC ATGTTATGACTGATTAATAAAAAGAATGTTTATAAAAACCCTTCTTTACAGGATTAAAAA AGTATTAAAAGAAACCATATTTGTGATTGCTAGTGTACCAACACTTTTAGAATTTTAAAG TTATTTACGGAACTGGCTATTGTTCCTTATTAGAGTTTTCAAGAAAACTGTCTATTGCTG GTAGTGTGATTTCATTTTGAAATTAAGACTTCGCATTTAATGAAAAAGCATTAAGATTTA ATGAAAATGTATTATTCCGATTCATTCATAAAGCAGTATCTCTCATATACCATGTGGAAT GNTATTAAAACTGGCATTTCTGAAAGCATTGGTACAAAGATATTTTAGACTTGTAGCACT AGCAGAGACATTGCATTAACCTATTGTAGATTTATAACTTTTATCCCGTTCAGTATACTG GCTCAGGATTACAAGCATACTTGGGGTTTGGTTCCTTATGCCCAAGATTACCTTTTGAAC TGTTTCTTTACAACAAATGGTTGGTGCCCCTGTACTTGGTCCCTAAAACATTTTTAGGCA TGATCATTCCTGGGCAAATTTGCCTTTAAATTTAGATATTGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004232 |
| Insert Size | 5500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004232.2, NP_004223.2 |
| RefSeq Size | 2650 bp |
| RefSeq ORF | 1608 bp |
| Locus ID | 9306 |
| UniProt ID | O14544 |
| Domains | SH2, SOCS |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202224 | SOCS6 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 6 (SOCS6) |
CNY 3,984.00 |
|
| RC202224L1 | Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), Myc-DDK-tagged |
CNY 6,384.00 |
|
| RC202224L2 | Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), mGFP tagged |
CNY 6,460.00 |
|
| RC202224L3 | Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC202224L4 | Lenti ORF clone of Human suppressor of cytokine signaling 6 (SOCS6), mGFP tagged |
CNY 6,460.00 |
|
| RG202224 | SOCS6 (tGFP-tagged) - Human suppressor of cytokine signaling 6 (SOCS6) |
CNY 5,584.00 |
|
| SC322430 | SOCS6 (untagged)-Human suppressor of cytokine signaling 6 (SOCS6) |
CNY 3,992.00 |
