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p53R2 (RRM2B) (NM_015713) Human Untagged Clone
CAT＃: SC124337
RRM2B (untagged)-Human ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), transcript variant 1
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MTDPS8A; MTDPS8B; P53R2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124337 sequence for NM_015713 edited (data generated by NextGen Sequencing)
ATGGGCGACCCGGAAAGGCCGGAAGCGGCCGGGCTGGATCAGGATGAGAGATCATCTTCA GACACCAACGAAAGTGAAATAAAGTCAAATGAAGAGCCACTCCTAAGAAAGAGTTCTCGC CGGTTTGTCATCTTTCCAATCCAGTACCCTGATATTTGGAAAATGTATAAACAGGCACAG GCTTCCTTCTGGACAGCAGAAGAGGTCGACTTATCAAAGGATCTCCCTCACTGGAACAAG CTTAAAGCAGATGAGAAGTACTTCATCTCTCACATCTTAGCCTTTTTTGCAGCCAGTGAT GGAATTGTAAATGAAAATTTGGTGGAGCGCTTTAGTCAGGAGGTGCAGGTTCCAGAGGCT CGCTGTTTCTATGGCTTTCAAATTCTCATCGAGAATGTTCACTCAGAGATGTACAGTTTG CTGATAGACACTTACATCAGAGATCCCAAGAAAAGGGAATTTTTATTTAATGCAATTGAA ACCATGCCCTATGTTAAGAAAAAAGCAGATTGGGCCTTGCGATGGATAGCAGATAGAAAA TCTACTTTTGGGGAAAGAGTGGTGGCCTTTGCTGCTGTAGAAGGAGTTTTCTTCTCAGGA TCTTTTGCTGCTATATTCTGGCTAAAGAAGAGAGGTCTTATGCCAGGACTCACTTTTTCC AATGAACTCATCAGCAGAGATGAAGGACTTCACTGTGACTTTGCTTGCCTGATGTTCCAA TACTTAGTAAATAAGCCTTCAGAAGAAAGGGTCAGGGAGATCATTGTTGATGCTGTCAAA ATTGAGCAGGAGTTTTTAACAGAAGCCTTGCCAGTTGGCCTCATTGGAATGAATTGCATT TTGATGAAACAGTACATTGAGTTTGTAGCTGACAGATTACTTGTGGAACTTGGATTCTCA AAGGTTTTTCAGGCAGAAAATCCTTTTGATTTTATGGAAAACATTTCTTTAGAAGGAAAA ACAAATTTCTTTGAGAAACGAGTTTCAGAGTATCAGCGTTTTGCAGTTATGGCAGAAACC ACAGATAACGTCTTCACCTTGGATGCAGATTTTTAA Clone variation with respect to NM_015713.4 >OriGene 5' read for NM_015713 unedited
TGTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGGAGGAGCTCAGTTCCCTC AGCGCCCGTAGCTTCGGCGGAGTCTGCGCGATGGGCGACCCGGAAAGGCCGGAAGCGGCC GGGCTGGATCAGGATGAGAGATCATCTTCAGACACCAACGAAAGTGAAATAAAGTCAAAT GAAGAGCCACTCCTAAGAAAGAGTTCTCGCCGGTTTGTCATCTTTCCAATCCAGTACCCT GATATTTGGAAAATGTATAAACAGGCACAGGCTTCCTTCTGGACAGCAGAAGAGGTCGAC TTATCAAAGGATCTCCCTCACTGGAACAAGCTTAAAGCAGATGAGAAGTACTTCATCTCT CACATCTTAGCCTTTTTTGCAGCCAGTGATGGAATTGTAAATGAAAATTTGGTGGAGCGC TTTAGTCAGGAGGTGCAGGTTCCAGAGGCTCGCTGTTTCTATGGCTTTCAAATTCTCATC GAGAATGTTCACTCAGAGATGTACAGTTTGCTGATAGACACTTACATCAGAGATCCCAAG AAAAGGGAATTTTTATTTAATGCAATTGAAACCATGCCCTATGTTAAGAAAAAAGCAGAT TGGGCCTTGCGATGGATAGCAGATAGAAAATCTACTTTTGGGGAAAGAGTGGTGGCCTTT GCTGCTGTAGAAGGAGTTTTCTTCTCAGGATCTTTTGCTGCTATATTCTGGCTAAAGAAG AGAGGTCTTATGCCAGNACTCACTTTTNTCAATGAACTCATCAGCAGAGATGAANGGACT TCACTGTGACTTGCTTGCCCTGATGTCCANTACTTAGTANATAAAGCTTCAAAAGAAGGT CAGGNAGATCATTGNTGATGCTGTCAAAATGANCAGGGAGTTTTACCAGAGCCCTTGCCA GTTGGCTCATTGGAATGAATGCATTTGATGAACGTACAATTGAGTTGTACTGAAGATTAC TGTGA >OriGene 3' read for NM_015713 unedited
GCTATGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAGAATAAACATTCCCTTTATTAGGGGA GCCCTTGCCCTTATAAAAAAACCTTCCTCAAAAGGGAAAGGGCCAAAAGGGGGAAAATCC CATAGTTTTTTTCAACATCCTAAGCCAAAAAAATAAAAAAACACCTATTTTTTTTGAAAA AAAAACAAATTTTGTCCATGCAGGCTGGGTTTGATTGACCATAAGGTTTTTCAGCAAAAA AATTTTAAATCCCCCCCCCATAATAAAGCTTTTTTTGGCCCCAGAAAATAGAAAATAACT TTGCTAAAGGGCCAAACTTTTGAAAAAATGAAAACCCAGTTGGAAAACAAAGTTTGTAAA AATATTGGGACCTTTTTTAACTGGCCAAAAAGCAATTTTTTTTTCCAGCCTTCCATTTTA ACTTACATTTTTTTAAACAAGATTAAGCCCCAAATTGAGGGGATTAAACCCTTTTTTCCT AAGGCCCGGGGAATATGAAATTCTTTTTAAAATCTTTAACTTTTTACAAAGGAGCAGAGC CCTTAAGGGGAAAGGGGGGGAAACAAAAAAATTTCAATTTTGGGCCATTCATCCAGATTT TGGTGGGGAAGATTTCCCAAGGCCACTACCAATTCACTCAACTGGGTTAAAAAACATAAT ACCTGGATGGAAGGATTAATTGGGCTTTTATTTACCCCCATCTGCAGCTTTATCATTAAA AACAAGCTCCTGACCTTAGCCCCTTAANTCAGTATCTACAAAAGAAATTTGGGACTCCTA TGCACGGGGGTGTAGCCTATTTTAAGGTAAAAGGCAAATGGTTATATTTTAAATTGCCAC CGGCCACTTTCCCAAAATCAATCCTGCCCAATAAAAATGGGCATGAAAGCGAATATTGGG TGTTCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_015713 |
| Insert Size | 5150 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_015713.3, NP_056528.2 |
| RefSeq Size | 4955 bp |
| RefSeq ORF | 1056 bp |
| Locus ID | 50484 |
| UniProt ID | Q7LG56 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Glutathione metabolism, Metabolic pathways, p53 signaling pathway, Purine metabolism, Pyrimidine metabolism |
| Gene Summary | This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010] Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210340 | RRM2B (Myc-DDK-tagged)-Human ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), transcript variant 1 |
CNY 3,656.00 |
|
| RC210340L3 | Lenti ORF clone of Human ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210340L4 | Lenti ORF clone of Human ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG210340 | RRM2B (tGFP-tagged) - Human ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), transcript variant 1 |
CNY 4,370.00 |
