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Deoxyguanosine kinase (DGUOK) (NM_080918) Human Untagged Clone
CAT＃: SC124293
DGUOK (untagged)-Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2
CN¥ 2,400.00
CN¥ 3,990.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | dGK; MTDPS3; NCPH; PEOB4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124293 sequence for NM_080918 edited (data generated by NextGen Sequencing)
ATGGCCGCGGGCCGCCTCTTTCTAAGTCGGCTTCGAGCACCCTTCAGTTCCATGGCCAAG AGCCCACTCGAGGGCGTTTCCTCCTCCAGAGGCCTGCACGCGGGGCGCGGGCCCCGAAGG CTCTCCATCGAAGGCAACATTGCTGTGGGAAAGTCCACGTTTGTGAAGTTACTCACGAAA ACTTACCCAGAATGGCACGTAGCTACAGAACCTGTAGCAACATGGCAGAATATCCAGGCT GCTGGCACCCAAAAAGCCTGCACTGCCCAAAGTCTTGGAAACTTGCTGGATATGATGTAC CGGGAGCCAGCACGATGGTCCTACACATTCCAGACATTTTCCTTTTTGAGCCGCCTGAAA GTACAGCTGGAGCCCTTCCCTGAGAAACTCTTACAGGCCAGGAAGCCAGTACAGATCTTT GAGAGGTCTGTGTACAGTGACAGGCTCCACTTTGAGGCTCTGATGAACATTCCAGTGCTG GTGTTGGATGTCAATGATGATTTTTCTGAGGAAGTAACCAAACAAGAAGACCTCATGAGA GAGGTAAACACCTTTGTAAAGAATCTGTAA Clone variation with respect to NM_080918.1 >OriGene 5' read for NM_080918 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGATCGCTGTGTGAATCG TGGGTGGGATGGCCGCGGGCCGCCTCTTTCTAAGTCGGCTTCGAGCACCCTTCAGTTCCA TGGCCAAGAGCCCACTCGAGGGCGTTTCCTCCTCCAGAGGCCTGCACGCGGGGCGCGGGC CCCGAAGGCTCTCCATCGAAGGCAACATTGCTGTGGGAAAGTCCACGTTTGTGAAGTTAC TCACGAAAACTTACCCAGAATGGCACGTAGCTACAGAACCTGTAGCAACATGGCAGAATA TCCAGGCTGCTGGCACCCAAAAAGCCTGCACTGCCCAAAGTCTTGGAAACTTGCTGGATA TGATGTACCGGGAGCCAGCACGATGGTCCTACACATTCCAGACATTTTCCTTTTTGAGCC GCCTGAAAGTACAGCTGGAGCCCTTCCCTGAGAAACTCTTACAGGCCAGGAAGCCAGTAC AGATCTTTGAGAGGTCTGTGTACAGTGACAGGCTCCACTTTGAGGCTCTGATGAACATTC CAGTGCTGGTGTTGGATGTCAATGATGATTTTTCTGAAGAAGTAACCAAACAAGAAGACC TCATGAGAGAGGTAAACACCTTTGTGAAGAATCTGTAACCAATACCATGAAGTTCAGGCT GTGATCTGGGCTCCCTGACCTTCTGAAGCTAGAAAAATGGTGTGTCTTCCAACCACCCTT TCCATCCCAGCCCCTTTCATTCCTTGGAGCCACTCTGGCGCTCAAGAGCTGGGTTGGTAA TTATGGTTAGACCTTGCCATGGTTTCTTTTGTACCTGAAGCATTTTGAAATAAAGGTTAC CTCAAGTTATGCCTGGTTTTCTTACAAAAAAAAAAAAAAACTCGATCCTAAATTGCGGCC GCGGGCATAACTGTTTCCTGACACGATCCCGGGGGGCTA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_080918 |
| Insert Size | 700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_080918.1, NP_550440.1 |
| RefSeq Size | 880 bp |
| RefSeq ORF | 570 bp |
| Locus ID | 1716 |
| UniProt ID | Q16854 |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Purine metabolism |
| Gene Summary | In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b)has the same N- and C-termini but is shorter compared to isoform 1. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223917 | DGUOK (Myc-DDK-tagged)-Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CN¥ 2,400.00 |
|
| RC223917L3 | Lenti ORF clone of Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2, Myc-DDK-tagged |
CN¥ 5,890.00 |
|
| RC223917L4 | Lenti ORF clone of Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2, mGFP tagged |
CN¥ 5,890.00 |
|
| RG223917 | DGUOK (tGFP-tagged) - Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CN¥ 4,000.00 |
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