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MRP1 (ABCC1) (NM_019902) Human Untagged Clone
CAT＃: SC124215
ABCC1 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (ABCC1), transcript variant 7
CNY 10,144.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MRP, ABCC, GS-X, MRP1, ABC29, DKFZp781G125, DKFZp686N04233 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124215 sequence for NM_019902 edited (data generated by NextGen Sequencing)
ATGGCGCTCCGGGGCTTCTGCAGCGCCGATGGCTCCGACCCGCTCTGGGACTGGAATGTC ACGTGGAATACCAGCAACCCCGACTTCACCAAGTGCTTTCAGAACACGGTCCTCGTGTGG GTGCCTTGTTTTTACCTCTGGGCCTGTTTCCCCTTCTACTTCCTCTATCTCTCCCGACAT GACCGAGGCTACATTCAGATGACACCTCTCAACAAAACCAAAACTGCCTTGGGATTTTTG CTGTGGATCGTCTGCTGGGCAGACCTCTTCTACTCTTTCTGGGAAAGAAGTCGGGGCATA TTCCTGGCCCCAGTGTTTCTGGTCAGCCCAACTCTCTTGGGCATCACCATGCTGCTTGCT ACCTTTTTAATTCAGCTGGAGAGGAGGAAGGGAGTTCAGTCTTCAGGGATCATGCTCACT TTCTGGCTGGTAGCCCTAGTGTGTGCCCTAGCCATCCTGAGATCCAAAATTATGACAGCC TTAAAAGAGGATGCCCAGGTGGACCTGTTTCGTGACATCACTTTCTACGTCTACTTTTCC CTCTTACTCATTCAGCTCGTCTTGTCCTGTTTCTCAGATCGCTCACCCCTGTTCTCGGAA ACCATCCACGACCCTAATCCCTGCCCAGAGTCCAGCGCTTCCTTCCTGTCGAGGATCACC TTCTGGTGGATCACAGGGTTGATTGTCCGGGGCTACCGCCAGCCCCTGGAGGGCAGTGAC CTCTGGTCCTTAAACAAGGAGGACACGTCGGAACAAGTCGTGCCTGTTTTGGTAAAGAAC TGGAAGAAGGAATGCGCCAAGACTAGGAAGCAGCCGGTGAAGGTCGTGTACTCCTCCAAG GATCCTGCCCAGCCGAAAGAGAGTTCCAAGGTGGATGCGAATGAGGAGGTGGAGGCTTTG ATCGTCAAGTCCCCACAGAAGGAGTGGAACCCCTCTCTGTTTAAGGTGTTATACAAGACC TTTGGGCCCTACTTCCTCATGAGCTTCTTCTTCAAGGCCATCCACGACCTGATGATGTTT TCCGGGCCGCAGATCTTAAAGTTGCTCATCAAGTTCGTGAACGACACGAAGGCCCCAGAC TGGCAGGGCTACTTCTACACCGTGCTGCTGTTTGTCACTGCCTGCCTGCAGACCCTCGTG CTGCACCAGTACTTCCACATCTGCTTCGTCAGTGGCATGAGGATCAAGACCGCTGTCATT GGGGCTGTCTATCGGAAGGCCCTGGTGATCACCAATTCAGCCAGAAAATCCTCCACGGTC GGGGAGATTGTCAACCTCATGTCTGTGGACGCTCAGAGGTTCATGGACTTGGCCACGTAC ATTAACATGATCTGGTCAGCCCCCCTGCAAGTCATCCTTGCTCTCTACCTCCTGTGGCTG AATCTGGGCCCTTCCGTCCTGGCTGGAGTGGCGGTGATGGTCCTCATGGTGCCCGTCAAT GCTGTGATGGCGATGAAGACCAAGACGTATCAGGTGGCCCACATGAAGAGCAAAGACAAT CGGATCAAGCTGATGAACGAAATTCTCAATGGGATCAAAGTGCTAAAGCTTTATGCCTGG GAGCTGGCATTCAAGGACAAGGTGCTGGCCATCAGGCAGGAGGAGCTGAAGGTGCTGAAG AAGTCTGCCTACCTGTCAGCCGTGGGCACCTTCACCTGGGTCTGCACGCCCTTTCTGGCG AGTGTCTCCCTCAAACGCCTGAGGATCTTTCTCTCCCATGAGGAGCTGGAACCTGACAGC ATCGAGCGACGGCCTGTCAAAGACGGCGGGGGCACGAACAGCATCACCGTGAGGAATGCC ACATTCACCTGGGCCAGGAGCGACCCTCCCACACTGAATGGCATCACCTTCTCCATCCCC GAAGGTGCTTTGGTGGCCGTGGTGGGCCAGGTGGGCTGCGGAAAGTCGTCCCTGCTCTCA GCCCTCTTGGCTGAGATGGACAAAGTGGAGGGGCACGTGGCTATCAAGGGCTCCGTGGCC TATGTGCCACAGCAGGCCTGGATTCAGAATGATTCTCTCCGAGAAAACATCCTTTTTGGA TGTCAGCTGGAGGAACCATATTACAGGTCCGTGATACAGGCCTGTGCCCTCCTCCCAGAC CTGGAAATCCTGCCCAGTGGGGATCGGACAGAGATTGGCGAGAAGGGCGTGAACCTGTCT GGGGGCCAGAAGCAGCGCGTGAGCCTGGCCCGGGCCGTGTACTCCAACGCTGACATTTAC CTCTTCGATGATCCCCTCTCAGCAGTGGATGCCCATGTGGGAAAACACATCTTTGAAAAT GTGATTGGCCCCAAGGGGATGCTGAAGAACAAGACGCGGATCTTGGTCACGCACAGCATG AGCTACTTGCCGCAGGTGGACGTCATCATCGTCATGAGTGGCGGCAAGATCTCTGAGATG GGCTCCTACCAGGAGCTGCTGGCTCGAGACGGCGCCTTCGCTGAGTTCCTGCGTACCTAT GCCAGCACAGAGCAGGAGCAGGATGCAGAGGAGAACGGGGTCACGGGCGTCAGCGGTCCA GGGAAGGAAGCAAAGCAAATGGAGAATGGCATGCTGGTGACGGACAGTGCAGGGAAGCAA CTGCAGAGACAGCTCAGCAGCTCCTCCTCCTATAGTGGGGACATCAGCAGGCACCACAAC AGCACCGCAGAACTGCAGAAAGCTGAGGCCAAGAAGGAGGAGACCTGGAAGCTGATGGAG GCTGACAAGGCGCAGACAGGGCAGGTCAAGCTTTCCGTGTACTGGGACTACATGAAGGCC ATCGGACTCTTCATCTCCTTCCTCAGCATCTTCCTTTTCATGTGTAACCATGTGTCCGCG CTGGCTTCCAACTATTGGCTCAGCCTCTGGACTGATGACCCCATCGTCAACGGGACTCAG GAGCACACGAAAGTCCGGCTGAGCGTCTATGGAGCCCTGGGCATTTCACAAGGGATCGCC GTGTTTGGCTACTCCATGGCCGTGTCCATCGGGGGGATCTTGGCTTCCCGCTGTCTGCAC GTGGACCTGCTGCACAGCATCCTGCGGTCACCCATGAGCTTCTTTGAGCGGACCCCCAGT GGGAACCTGGTGAACCGCTTCTCCAAGGAGCTGGACACAGTGGACTCCATGATCCCGGAG GTCATCAAGATGTTCATGGGCTCCCTGTTCAACGTCATTGGTGCCTGCATCGTTATCCTG CTGGCCACGCCCATCGCCGCCATCATCATCCCGCCCCTTGGCCTCATCTACTTCTTCGTC CAGAGGTTCTACGTGGCTTCCTCCCGGCAGCTGAAGCGCCTCGAGTCGGTCAGCCGCTCC CCGGTCTATTCCCATTTCAACGAGACCTTGCTGGGGGTCAGCGTCATTCGAGCCTTCGAG GAGCAGGAGCGCTTCATCCACCAGAGTGACCTGAAGGTGGACGAGAACCAGAAGGCCTAT TACCCCAGCATCGTGGCCAACAGGTGGCTGGCCGTGCGGCTGGAGTGTGTGGGCAACTGC ATCGTTCTGTTTGCTGCCCTGTTTGCGGTGATCTCCAGGCACAGCCTCAGTGCTGGCTTG GTGGGCCTCTCAGTGTCTTACTCATTGCAGGTCACCACGTACTTGAACTGGCTGGTTCGG ATGTCATCTGAAATGGAAACCAACATCGTGGCCGTGGAGAGGCTCAAGGAGTATTCAGAG ACTGAGAAGGAGGCGCCCTGGCAAATCCAGGAGACAGCTCCGCCCAGCAGCTGGCCCCAG GTGGGCCGAGTGGAATTCCGGAACTACTGCCTGCGCTACCGAGAGGACCTGGACTTCGTT CTCAGGCACATCAATGTCACGATCAATGGGGGAGAAAAGGTCGGCATCGTGGGGCGGACG GGAGCTGGGAAGTCGTCCCTGACCCTGGGCTTATTTCGGATCAACGAGTCTGCCGAAGGA GAGATCATCATCGATGGCATCAACATCGCCAAGATCGGCCTGCACGACCTCCGCTTCAAG ATCACCATCATCCCCCAGGACCCTGTTTTGTTTTCGGGTTCCCTCCGAATGAACCTGGAC CCATTCAGCCAGTACTCGGATGAAGAAGTCTGGACGTCCCTGGAGCTGGCCCACCTGAAG GACTTCGTGTCAGCCCTTCCTGACAAGCTAGACCATGAATGTGCAGAAGGCGGGGAGAAC CTCAGTGTCGGGCAGCGCCAGCTTGTGTGCCTAGCCCGGGCCCTGCTGAGGAAGACGAAG ATCCTTGTGTTGGATGAGGCCACGGCAGCCGTGGACCTGGAAACGGACGACCTCATCCAG TCCACCATCCGGACACAGTTCGAGGACTGCACCGTCCTCACCATCGCCCACCGGCTCAAC ACCATCATGGACTACACAAGGGTGATCGTCTTGGACAAAGGAGAAATCCAGGAGTACGGC GCCCCATCGGACCTCCTGCAGCAGAGAGGTCTTTTCTACAGCATGGCCAAAGACGCCGGC TTGGTGTGA Clone variation with respect to NM_019902.1 350 c=>t;825 t=>c;1062 t=>c >OriGene 5' read for NM_019902 unedited
ACCCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA ATTCGGCACGAGGCCGGCATGGCGCTCCGGGGCTTCTGCAGCGCCGATGGCTCCGACCCG CTCTGGGACTGGAATGTCACGTGGAATACCAGCAACCCCGACTTCACCAAGTGCTTTCAG AACACGGTCCTCGTGTGGGTGCCTTGTTTTTACCTCTGGGCCTGTTTCCCCTTCTACTTC CTCTATCTCTCCCGACATGACCGAGGCTACATTCAGATGACACCTCTCAACAAAACCAAA ACTGCCTTGGGATTTTTGCTGTGGATCGTCTGCTGGGCAGACCTCTTCTACTCTTTCTGG GAAAGAAGTCGGGGCATATTCCTGGCCCCAGTGNTTCTGGTCAGCCCAACTCTCTTGGGC ATCACCATGCTGCTTGCTACCTTTTTAATTCCCCGGAGATCACCACCCCTTCCACTCTCC CCCTTTCCCTTCCTCCCCTCCTCCCGCNNNNNNNNNNCNNNCNNCNNCCCNNNNNNTCNN NNCCCNCCNNNCCCNCCCCCCCCCCCCNCCCCNCCCCCNCCTCCCCCCCCCCCCCCCCNN NCCNCCCCCCCCCCCCCCCCCCCCCCCNCCCCCCCCCCTCCCCCCNCNCCCCCCCCCCGC CCCCCCNCCCNCCCCCCCCCCNCNNCCCNTNCCCCCCNCTCNNCCCCCCCCCCNNCCCCC CCTCNCNCCCCACCCCCCCCCCNCCCCCCCCCCCCCCCCCCNCNCCNCCNNCCCCNCNCC CCCCNNNCCCCCCCCCCCNNCCCNNNCCCCCCCCCCCCCCCCCCCCNNCCCCCCCCCCCC CCCCCCCNCTTCTTTTCCTCCCCTTCTCTCCCTTCTTCCCCCCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019902 |
| Insert Size | 6000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_019902.1, NP_063957.1 |
| RefSeq Size | 5780 bp |
| RefSeq ORF | 4449 bp |
| Locus ID | 4363 |
| Domains | ABC_membrane, ABC_tran, AAA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012] Transcript Variant: This variant (7) lacks exon 13, as compared to the predominant, full-length transcript variant 1. This results in a 49-amino acid in-frame deletion in the coding region. |
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