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IFITM2 (NM_006435) Human Untagged Clone
CAT＃: SC124192
IFITM2 (untagged)-Human interferon induced transmembrane protein 2 (1-8D) (IFITM2)
CNY 1,200.00
CNY 3,990.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1-8D; DSPA2c |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124192 sequence for NM_006435 edited (data generated by NextGen Sequencing)
ATGAACCACATTGTGCAAACCTTCTCTCCTGTCAACAGCGGCCAGCCTCCCAACTACGAG ATGCTCAAGGAGGAGCAGGAAGTGGCTATGCTGGGGGCGCCCCACAACCCTGCTCCCCCG ATGTCCACCGTGATCCACATCCGCAGCGAGACCTCCGTGCCTGACCATGTCGTCTGGTCC CTGTTCAACACCCTCTTCATGAACACCTGCTGCCTGGGCTTCATAGCATTCGCCTACTCC GTGAAGTCTAGGGACAGGAAGATGGTTGGCGACGTGACCGGGGCCCAGGCCTATGCCTCC ACCGCCAAGTGCCTGAACATCTGGGCCCTGATTTTGGGCATCTTCATGACCATTCTGCTC ATCATCATCCCAGTGTTGGTCGTCCAGGCCCAGCGATAG Clone variation with respect to NM_006435.2 98 t=>c;171 g=>c;234 g=>c >OriGene 5' read for NM_006435 unedited
TTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCCGATCACCGCTGG TCACCATGAACCACATTGTGCAAACCTTCTCTCCTGTCAACAGCGGCCAGCCTCCCAACT ACGAGATGCTCAAGGAGGAGCAGGAAGTGGCTATGCTGGGGGCGCCCCACAACCCTGCTC CCCCGATGTCCACCGTGATCCACATCCGCAGCGAGACCTCCGTGCCTGACCATGTCGTCT GGTCCCTGTTCAACACCCTCTTCATGAACACCTGCTGCCTGGGCTTCATAGCATTCGCCT ACTCCGTGAAGTCTAGGGACAGGAAGATGGTTGGCGACGTGACCGGGGCCCAGGCCTATG CCTCCACCGCCAAGTGCCTGAACATCTGGGCCCTGATTTTGGGCATCTTCATGACCATTC TGCTCATCATCATCCCAGTGTTGGTCGTCCAGGCCCAGCGATAGATCAGGAGGCATCATT GAGGCCAGGAGCTCTGCCCGTGACCTGTATCCCACGTACTCTATCTTCCATTCCTCGCCC TGCCCCCAGAGGCCAGGAGCTCTGCCCTTGACCTGTATTCCACTTACTCCACCTTCCATT CCTCGCCCTGTCCCCACAGCCGAGTCCTGCATCAGCCCTTTATCCTCACACGCTTTTCTA CAATGGCATTCAATAAAGTGTATANTGTTTCTGGTAAAAAAAAAAAAAAAAACTCGACTC TAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCNTGTGAC CCCTCCCCGTGCCTCTCCTGGCCCCTGAAGTTGCCACTNCAGTGCCCACCAGCCTTTGTC TAATAAAATAAAGTGCATCATTTTGTCTGACTANGGTGTCTCATAATATGTGGGGGGGGG GGGGGGGNGTGGNNNNNNNNNNNGGGAGGGGGNNNTNGGAGAGAAAACT >OriGene 3' read for NM_006435 unedited
NNTTATCTCTGNNACCGCGGCCCGCATTCTNANNATCGAGTTTTTTTTTTTTTTTTTTAC CAAAAACATATACACTTTATTGAATGCCATTGTAGAAAAGCGTGTGAGGATAAAGGGCTG ATGCAGGACTCGGCTGTGGGGACAGGGCGAGGAATGGAAGGTGGAGTAAGTGGAATACAG GTCAAGGGCAGAGCTCCTGGCCTCTGGGGGCAGGGCGAGGAATGGAAGATAGAGTACGTG GGATACAGGTCACGGGCAGAGCTCCTGGCCTCAATGATGCCTCCTGATCTATCGCTGGGC CTGGACGACCAACACTGGGATGATGATGAGCAGAATGGTCATGAAGATGCCCAAAATCAG GGCCCAGATGTTCAGGCACTTGGCGGTGGAGGCATAGGCCTGGGCCCCGGTCACGTCGCC AACCATCTTCCTGTCCCTAGACTTCACGGAGTAGGCGAATGCTATGAAGCCCAGGCAGCA GGTGTTCATGAAGAGGGTGTTGAACAGGGACCAGACGACATGGTCAGGCACGGAGGTCTC GCTGCGGATGTGGATCACGGTGGACATCGGGGGAGCAGGGTTGTGGGGCGCCCCCAGCAT AGCCACTTCCTGCTCCTCCTTGAGCATCTCGTANTTGGGAGGCTGGCCGCTGTTGACAGG AGAGAAAGGTTGCACAATGTGGTTCATGGTGACCCAGCGTGATCGGGCCTCGTGCCGAAT TCGCGGCCGCCCTATAGTGAGTCGTATTACAAATTCTGACGGTTCACTAAACGAGCTCTG CTTTATAGACCTNCCACCGTACACGCCTACCGNCCATTTGCGTCACGGGGGCGGGGNTAT TACCACATTTTGAAAGGCCCNGTGATTTTGGTGCCAAACAAACTCCNATTGACGTCAATG GGGTGGAAACTTGGAAAATCCCGTGAGTCAAACCGTTATCACGCCCATG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006435 |
| Insert Size | 670 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006435.1, NP_006426.1 |
| RefSeq Size | 905 bp |
| RefSeq ORF | 399 bp |
| Locus ID | 10581 |
| UniProt ID | Q01629 |
| Domains | CD225 |
| Protein Families | Transmembrane |
| Gene Summary | IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag
,Ahi, YS;Yimer, D;Shi, G;Majdoul, S;Rahman, K;Rein, A;Compton, AA;,
mBio
,PubMed ID 31964738
[IFITM2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202067 | IFITM2 (Myc-DDK-tagged)-Human interferon induced transmembrane protein 2 (1-8D) (IFITM2) |
CNY 1,200.00 |
|
| RC202067L1 | Lenti ORF clone of Human interferon induced transmembrane protein 2 (1-8D) (IFITM2), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC202067L2 | Lenti ORF clone of Human interferon induced transmembrane protein 2 (1-8D) (IFITM2), mGFP tagged |
CNY 5,890.00 |
|
| RC202067L3 | Lenti ORF clone of Human interferon induced transmembrane protein 2 (1-8D) (IFITM2), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC202067L4 | Lenti ORF clone of Human interferon induced transmembrane protein 2 (1-8D) (IFITM2), mGFP tagged |
CNY 3,600.00 |
|
| RG202067 | IFITM2 (tGFP-tagged) - Human interferon induced transmembrane protein 2 (1-8D) (IFITM2) |
CNY 2,800.00 |
