ACCN1 (ASIC2) (NM_001094) Human Untagged Clone
CAT#: SC124011
ASIC2 (untagged)-Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2
CNY 3,824.00
CNY 7,220.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ACCN; ACCN1; ASIC2a; BNaC1; BNC1; hBNaC1; MDEG |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_001094, the custom clone sequence may differ by one or more nucleotides
ATGGACCTCAAGGAAAGCCCCAGTGAGGGCAGCCTGCAACCTTCTAGCATCCAGATCTTTGCCAACACCT CCACCCTCCATGGCATCCGCCACATCTTCGTGTATGGGCCGCTGACCATCCGGCGTGTGCTGTGGGCAGT GGCCTTCGTGGGCTCTCTGGGCCTGCTGCTGGTGGAGAGCTCTGAGAGGGTGTCCTACTACTTCTCCTAC CAGCATGTCACTAAGGTGGACGAAGTGGTGGCTCAAAGCCTGGTCTTCCCAGCTGTGACCCTCTGTAACC TGAATGGCTTCCGGTTCTCCAGGCTCACCACCAATGACCTGTACCATGCTGGGGAGCTGCTGGCCCTGCT GGATGTCAACCTGCAGATCCCGGACCCCCATCTGGCTGACCCCTCCGTGCTGGAGGCCCTGCGGCAGAAG GCCAACTTCAAGCACTACAAACCCAAGCAGTTCAGCATGCTGGAGTTCCTGCACCGTGTGGGCCATGACC TGAAGGATATGATGCTCTACTGCAAGTTCAAAGGGCAGGAGTGCGGCCACCAAGACTTCACCACAGTGTT TACAAAATATGGGAAGTGTTACATGTTTAACTCAGGCGAGGATGGCAAACCTCTGCTCACCACGGTCAAG GGGGGGACAGGCAACGGGCTGGAGATCATGCTGGACATTCAGCAGGATGAGTACCTGCCCATCTGGGGAG AGACAGAGGAAACGACATTTGAAGCAGGAGTGAAAGTTCAGATCCACAGTCAGTCTGAGCCACCTTTCAT CCAAGAGCTGGGCTTTGGGGTGGCTCCAGGGTTCCAGACCTTTGTGGCCACACAGGAGCAGAGGCTCACA TACCTGCCCCCACCGTGGGGTGAGTGCCGATCCTCAGAGATGGGCCTCGACTTTTTTCCTGTTTACAGCA TCACCGCCTGTAGGATTGACTGTGAGACCCGCTACATTGTGGAAAACTGCAACTGCCGCATGGTTCACAT GCCAGGGGATGCCCCTTTTTGTACCCCTGAGCAGCACAAGGAGTGTGCAGAGCCTGCCCTAGGTCTGTTG GCGGAAAAGGACAGCAATTACTGTCTCTGCAGGACACCCTGCAACCTAACCCGCTACAACAAAGAGCTCT CCATGGTGAAGATCCCCAGCAAGACATCAGCCAAGTACCTTGAGAAGAAATTTAACAAATCAGAAAAATA TATCTCAGAGAACATCCTTGTTCTGGATATATTTTTTGAAGCTCTCAATTATGAGACAATTGAACAGAAG AAGGCGTATGAAGTTGCTGCCTTACTTGGTGATATTGGTGGTCAGATGGGATTGTTCATTGGTGCTAGTA TCCTTACAATACTAGAGCTCTTTGATTATATTTATGAGCTGATCAAAGAGAAGCTATTAGACCTGCTTGG CAAAGAGGAGGACGAAGGGAGCCACGATGAGAATGTGAGTACTTGTGACACAATGCCAAACCACTCTGAA ACCATCAGTCACACTGTGAACGTGCCCCTGCAGACGACCCTGGGGACCTTGGAGGAGATTGCCTGCTGA >OriGene 5' read for NM_001094 unedited
GGTTAGCGGTCACTATAGGGNCGGCCGCGCNNNNNNNGGAGCATCACCCTGATGTCTCCC CAAGAAAAACCAGCCGTGCTTATCGCCTGGAAAAAATCAAGAGCTAGAGGGTGAATGGGT TAGGGGTAAACGGGGACCCCTGTCAACGTGATAAAGGCTCTCAGGATAAACTCACAGCAT CTGGCGCGATGCTTGCCTTGCGTTCTCTCCCCTGAACGTCAAGGTTTAAGCAGAGCCCGA GGACTGGGAGCTCTTCTCTGAAATTCGATCAACCTGAAGCCAGTTGCGGAACTGCACGGG GTCCCGATGGACCTCAAGGAAAGCCCCAATGAGGGCAGCCTGCAACCTTCTAGCATCCAG ATCTTTGCCAACACCTCCACCCTCCATGGCATCCGCCACATCTTCGTGTATGGGCCGCTG ACCATCCGGCGTGTGCTGTGGGCAATGGCCTTCGTGGGCTCTCTGGGCCTGCTGCTGGTG GAGAGCTCTGAGAGGGTGTCCTACTACTTCTCCTACCAGCATGTCACTAAGGTGGACGAA GTGGTGGCTCAAAACCCGGTCTTCCCAGCTGTGACCCTCTGGAACCTGAATGGCTTCCGG GTCTCCAGGCTCACCACCCAAAGACCTGTACCATGCTGGGGAGCTGCTGGCCCTGCTGAT GTCAACCTGCAGATCCCGGACCCCCATCTGGCTGACCCCTCCCTGCTGGAAGCCCTGCGG CAGAAAGCCACG >OriGene 3' read for NM_001094 unedited
CTTCTCTCGTGGCTCCCTTCGTCCTAGGTNNGNGAAGCAGGTCTAATAGCTTCTCTTTGA TCAGCTCATAAATATTTTCAAAGAGCTCTAGTATTGTAAGGATACTAGCGCCAATGAACA ATCCCATCTGACCACCAATATCACCAATAATAGCAGCAACTTCATACGCCTTCTTCTGTT CAATTGTCTCATAATTGAGAGCTTCAAAAAATATATCCAGAACAAGGATGTTCTCTGAGA TATATTTTTCTGATTTGTTAAATTTCTTCTCAAGGTACTTGGCTGATGTCTTGCTGGGGA TCTTCACCATGGAGAGCTCTTTGTTGTAACGGGTTAAGTTGCAAGGTGTCCTGCAGAGAC AGTAATTGCTGTCCTTTTCCGCCAACAGACCTAGGGCAGGCTCTGCACACTCCTTGTGCT GCTCAGGGGTACAAAANAGGGCATCCCCTGGCATGTGAACCATGCGGCAGTTGCAGTTTT CCACAATGTAGCGGGTCTCACAGTCAATCCTACAGGCGGTGATGCTGTAAACAGGAAAAA AGTCCAGGCCCATCTCTGAGGATCGGCACTCACCCCACGGGGGGGGCAAGGTATGTAAGC CCTCTGCTCCCTGTGTGGCCACAAAGGTCTGGAACCCTGGAACCCACCCCAAACCCAACT CTTGGATGAAAGGTGGCTAAGACTGACTGTGGATCTGAACTTTAACTCCTGCTTCAAATG TCGTTTCCTCTGG |
Restriction Sites | NotI-NotI |
ACCN | NM_001094 |
Insert Size | 3500 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001094.4, NP_001085.2 |
RefSeq Size | 2747 bp |
RefSeq ORF | 1539 bp |
Locus ID | 40 |
UniProt ID | Q16515 |
Protein Families | Druggable Genome, Ion Channels: Other |
Protein Pathways | Taste transduction |
Gene Summary | This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012] Transcript Variant: This variant (MDEG1) uses an alternate 5'-terminal exon, compared to variant MDEG2, resulting in a shorter isoform (MDEG1) with a distinct N-terminus, compared to isoform MDEG2. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC210409 | ASIC2 (Myc-DDK-tagged)-Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2 |
CNY 3,816.00 |
|
RC210409L1 | Lenti ORF clone of Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, Myc-DDK-tagged |
CNY 6,216.00 |
|
RC210409L2 | Lenti ORF clone of Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, mGFP tagged |
CNY 6,460.00 |
|
RC210409L3 | Lenti ORF clone of Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, Myc-DDK-tagged |
CNY 6,216.00 |
|
RC210409L4 | Lenti ORF clone of Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, mGFP tagged |
CNY 6,216.00 |
|
RG210409 | ASIC2 (tGFP-tagged) - Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2 |
CNY 5,416.00 |