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FGFRL1 (NM_021923) Human Untagged Clone
CAT＃: SC123844
FGFRL1 (untagged)-Human fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3
CNY 3,760.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FGFR-5; FGFR5; FHFR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC123844 sequence for NM_021923 edited (data generated by NextGen Sequencing)
ATGACGCCGAGCCCCCTGTTGCTGCTCCTGCTGCCGCCGCTGCTGCTGGGGGCCTTCCCGCCGGCCGCCG CCGCCCGAGGCCCCCCAAAGATGGCGGACAAGGTGGTCCCACGGCAGGTGGCCCGGCTGGGCCGCACTGT GCGGCTGCAGTGCCCAGTGGAGGGGGACCCGCCGCCGCTGACCATGTGGACCAAGGATGGCCGCACCATC CACAGCGGCTGGAGCCGCTTCCGCGTGCTGCCGCAGGGGCTGAAGGTGAAGCAGGTGGAGCGGGAGGATG CCGGCGTGTACGTGTGCAAGGCCACCAACGGCTTCGGCAGCCTGAGCGTCAACTACACCCTCGTCGTGCT GGATGACATTAGCCCAGGGAAGGAGAGCCTGGGGCCCGACAGCTCCTCTGGGGGTCAAGAGGACCCCGCC AGCCAGCAGTGGGCACGACCGCGCTTCACACAGCCCTCCAAGATGAGGCGCCGGGTGATCGCACGGCCCG TGGGTAGCTCCGTGCGGCTCAAGTGCGTGGCCAGCGGGCACCCTCGGCCCGACATCACGTGGATGAAGGA CGACCAGGCCTTGACGCGCCCAGAGGCCGCTGAGCCCAGGAAGAAGAAGTGGACACTGAGCCTGAAGAAC CTGCGGCCGGAGGACAGCGGCAAATACACCTGCCGCGTGTCGAACCGCGCGGGCGCCATCAACGCCACCT ACAAGGTGGATGTGATCCAGCGGACCCGTTCCAAGCCCGTGCTCACAGGCACGCACCCCGTGAACACGAC GGTGGACTTCGGGGGGACCACGTCCTTCCAGTGCAAGGTGCGCAGCGACGTGAAGCCGGTGATCCAGTGG CTGAAGCGCGTGGAGTACGGCGCCGAGGGCCGCCACAACTCCACCATCGATGTGGGCGGCCAGAAGTTTG TGGTGCTGCCCACGGGTGACGTGTGGTCGCGGCCCGACGGCTCCTACCTCAATAAGCTGCTCATCACCCG TGCCCGCCAGGACGATGCGGGCATGTACATCTGCCTTGGCGCCAACACCATGGGCTACAGCTTCCGCAGC GCCTTCCTCACCGTGCTGCCAGACCCAAAACCGCCAGGGCCACCTGTGGCCTCCTCGTCCTCGGCCACTA GCCTGCCGTGGCCCGTGGTCATCGGCATCCCAGCCGGCGCTGTCTTCATCCTGGGCACCCTGCTCCTGTG GCTTTGCCAGGCCCAGAAGAAGCCGTGCACCCCCGCGCCTGCCCCTCCCCTGCCTGGGCACCGCCCGCCG GGGACGGCCCGCGACCGCAGCGGAGACAAGGACCTTCCCTCGTTGGCCGCCCTCAGCGCTGGCCCTGGTG TGGGGCTGTGTGAGGAGCATGGGTCTCCGGCAGCCCCCCAGCACTTACTGGGCCCAGGCCCAGTTGCTGG CCCTAAGTTGTACCCCAAACTCTACACAGACATCCACACACACACACACACACACTCTCACACACACTCA CACGTGGAGGGCAAGGTCCACCAGCACATCCACTATCAGTGCTAG Clone variation with respect to NM_021923.3 >OriGene 5' read for NM_021923 unedited
CTCATGCAAGACACCGGGACCGATCCATCCTCCGGACTCTATCCTAGGCCGCGGGACGGA TAACAATTTCACACAGGAAACAGCTATGACCATTAGGCCTATTTAGGTGACACTATAGAA CAAGTTTGTACAAAAAAGCAGGCTGGTACCGGTCCGGAATTCCCGGGATCCCTTCTGTTT TTAGAGAGCGGTCTGGGCCCGGCCCGGGGCTGCGCAGAGGTCAGACTGCCGCGGGCAGGG CCGGAGCCTGCTCTGGGGGTCGCGGAGGTGTCTCGAGAGTTGAGGACCCGACCCGGGCGC GCGCGGGCGCAGGTCCGGACAGGCCGAGATGACGCCGAGCCCCCTGTTGCTGCTCCTGCT GCCGCCGCTGCTGCTGGGGGCCTTCCCGCCGGCCGCCGCCGCCCGAGGCCCCCCAAAGAT GGCGGACAAGGTGGTCCCACGGCAGGTGGCCCGGCTGGGCCGCACTGTGCGGCTGCAGTG CCCAGTGGAGGGGGACCCGCCGCCGCTGACCATGTGGACCAAGGATGGCCGCACCATCCA CAGCGGCTGGAGCCGCTTCCGCGTGCTGCCGCATGGGCTGAATGTGAATCATGTGGAGCG GGAGGATGCCGGCGTGTACGTGTGCAAGGCCACCAACGGCTTCGGCAGCCTGAGCGTCAA CTACACCCTCGTCGTGCTGGATGACATTAGCCCATGGAAGGAGAGCCTGGGGCCCGACAG CTCCTCTGGGGGTCAAGAGGACCCCGCCAGCCAGCAGTGGGCACGACCGCGCTTACACAG CCCTCCAGATGAGGCGCCGGGTGATCGCACGGCCCGTGGGTAGCTNCGTGNCGCTCAAGT GCGTGGCCAGCGGGCACCCTCGGCCCGACATCACGTGGATGAATGACGACAAGCCCTGAC CCGCCCATAGTCCGCTGATGCCAAGAAGAATAAT |
| Restriction Sites | Please inquire |
| ACCN | NM_021923 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021923.3, NP_068742.2 |
| RefSeq Size | 3105 bp |
| RefSeq ORF | 1515 bp |
| Locus ID | 53834 |
| UniProt ID | Q8N441 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) has an alternate 5' UTR, and encodes the same isoform, as compared to variant 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
,Vögtle, T;Sharma, S;Mori, J;Nagy, Z;Semeniak, D;Scandola, C;Geer, MJ;Smith, CW;Lane, J;Pollack, S;Lassila, R;Jouppila, A;Barr, AJ;Ogg, DJ;Howard, TD;McMiken, HJ;Warwicker, J;Geh, C;Rowlinson, R;Abbott, WM;Eckly, A;Schulze, H;Wright, GJ;Mazharian, A;Fütterer, K;Rajesh, S;Douglas, MR;Senis, YA;,
Elife
,PubMed ID 31436532
[FGFRL1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212657 | FGFRL1 (Myc-DDK-tagged)-Human fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3 |
CNY 3,990.00 |
|
| RC212657L3 | Lenti-ORF clone of FGFRL1 (Myc-DDK-tagged)-Human fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3 |
CNY 5,890.00 |
|
| RC212657L4 | Lenti-ORF clone of FGFRL1 (mGFP-tagged)-Human fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3 |
CNY 5,890.00 |
|
| RG212657 | FGFRL1 (tGFP-tagged) - Human fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3 |
CNY 4,370.00 |
