MCP4 (CCL13) (BC008621) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	chemokine (C-C; CK-beta-10; CKb10; MCP-4; MGC17134; monocyte chemoattractant protein 4; monocyte chemotactic protein 4; NCC-1; NCC1; new CC chemokine 1; SCYA13; SCYL1; small inducible cytokine A13; small inducible cytokine subfamily A (Cys-Cys), member 13
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC008621 edited AAGAAACATTGTGAAATCTCCAACTCTTAACCTTCAACATGAAAGTCTCTGCAGTGCTTC TGTGCCTGCTGCTCATGACAGCAGCTTTCAACCCCCAGGGACTTGCTCAGCCAGATGCAC TCAACGTCCCATCTACTTGCTGCTTCACATTTAGCAGTAAGAAGATCTCCTTGCAGAGGC TGAAGAGCTATGTGATCACCACCAGCAGGTGTCCCCAGAAGGCTGTCATCTTCAGAACCA AACTGGGCAAGGAGATCTGTGCTGACCCAAAGGAGAAGTGGGTCCAGAATTATATGAAAC ACCTGGGCCGGAAAGCTCACACCCTGAAGACTTGAACTCTGCTACCCCTACTGAAATCAA GCTGGAGTACGTGAAATGACTTTTCCATTCTCCTCTGGCCTCCTCTTCTATGCTTTGGAA TACTTCTACCATAATTTTCAAATAGGATGCATTCGGTTTTGTGATTCAAAATGTACTATG TGTTAAGTAATATTGGCTATTATTTGACTTGTTGCTGGTTTGGAGTTTATTTGAGTATTG CTGATCTTTTCTAAAGCAAGGCCTTGAGCAAGTAGGTTGCTGTCTCTAAGCCCCCTTCCC TTCCACTATGAGCTGCTGGCAGTGGGTTTGTATTCGGTTCCCAGGGGTTGAGAGCATGCC TGTGGGAGTCATGGACATGAAGGGATGCTGCAATGTAGGAAGGAGAGCTCTTTGTGAATG TGAGGTGTTGCTAAATATGTTATTGTGGAAAGATGAATGCAATAGTAGGACTGCTGACAT TTTGCAGAAAATACATTTTATTTAAAATCTCCTAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC008621 unedited GGGCACTTNGATTTGTAATCCCACTCACTAAGGCGGCCGCGCATCCCGGGGTATCGTCGA CCCACGCGTCCGAAGAAACATTGTGAAATCTCCAACTCTTAACCTTCAACATGAAAGTCT CTGCAGTGCTTCTGTGCCTGCTGCTCATGACAGCAGCTTTCAACCCCCAGGGACTTGCTC AGCCAGATGCACTCAACGTCCCATCTACTTGCTGCTTCACATTTAGCAGTAAGAAGATCT CCTTGCAGAGGCTGAAGAGCTATGTGATCACCACCAGCAGGTGTCCCCAGAAGGCTGTCA TCTTCAGAACCAAACTGGGCAAGGAGATCTGTGCTGACCCAAAGGAGAAGTGGGTCCAGA ATTATATGAAACACCTGGGCCGGAAAGCTCACACCCTGAAGACTTGAACTCTGCTACCCC TACTGAAATCAAGCTGGAGTACGTGAAATGACTTTTCCATTCTCCTCTGGCCTCCTCTTC TATGCTTTGGAATACTTCTACCATAATTTTCAAATAGGATGCATTCGGTTTTGTGATTCA AAATGTACTATGTGTTAAGTAATATTGGCTATTATTTGACTTGTTGCTGGTTTGGAGTTT ATTTGAGTATTGCTGATCTTTTCTAAAGCAAGGCCTTGAGCAAGTAGGTTGCTGTCTCTA AGCCCCCTTCCCTTCCACTATGAGCTGCTGGCAGTGGGTTTGTATTCGGTTCCCAGGGGT TGAGAGCATGCCTGTGGGAGTCATGGACATGAAGGGATGCTGCAATGTANGAAGGAGAGC TCTTTGTGAATGTGAGGTGTTGCTAAATATGTTATTGTGGAAAAGATGAATGCATAGTAG GACTGCTGACATTTTGCAGAAAATACATTTATTTTAAATCTCCTAAAAAAAAAAAAAAAG GCGGCCGCGGTA
Restriction Sites	Please inquire
ACCN	BC008621
Insert Size	829 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC008621.1, AAH08621.1
RefSeq Size	829 bp
Locus ID	6357
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway
Gene Summary	This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014]

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