Dopamine D2 Receptor (DRD2) (BC021195) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	D2DR; D2R; dopamine receptor D2; dopamine receptor D2 isoform; seven transmembrane helix receptor
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC021195 edited GCGGGAGCTGGAAGCCTCAAGCAGCCGGCGCCGTCTCTGCCCCGGGGCGCCCTATGGCTT GAAGAGCCTGGCCACCCAGTGGCTCCACCGCCCTGATGGATCCACTGAATCTGTCCTGGT ATGATGATGATCTGGAGAGGCAGAACTGGAGCCGGCCCTTCAACGGGTCAGACGGGAAGG CGGACAGACCCCACTACAACTACTATGCCACACTGCTCACCCTGCTCATCGCTGTCATCG TCTTCGGCAACGTGCTGGTGTGCATGGCTGTGTCCCGCGAGAAGGCGCTGCAGACCACCA CCAACTACCTGATCGTCAGCCTCGCAGTGGCCGACCTCCTCGTCGCCACACTGGTCATGC CCTGGGTTGTCTACCTGGAGGTGGTAGGTGAGTGGAAATTCAGCAGGATTCACTGTGACA TCTTCGTCACTCTGGACGTCATGATGTGCACGGCGAGCATCCTGAACTTGTGTGCCATCA GCATCGACAGGTACACAGCTGTGGCCATGCCCATGCTGTACAATACGCGCTACAGCTCCA AGCGCCGGGTCACCGTCATGATCTCCATCGTCTGGGTCCTGTCCTTCACCATCTCCTGCC CACTCCTCTTCGGACTCAATAACGCAGACCAGAACGAGTGCATCATTGCCAACCCGGCCT TCGTGGTCTACTCCTCCATCGTCTCCTTCTACGTGCCCTTCATTGTCACCCTGCTGGTCT ACATCAAGATCTACATTGTCCTCCGCAGACGCCGCAAGCGAGTCAACACCAAACGCAGCA GCCGAGCTTTCAGGGCCCACCTGAGGGCTCCACTAAAGGGCAACTGTACTCACCCCGAGG ACATGAAACTCTGCACCGTTATCATGAAGTCTAATGGGAGTTTCCCAGTGAACAGGCGGA GAGTGGAGGCTGCCCGGCGAGCCCAGGAGCTGGAGATGGAGATGCTCTCCAGCACCAGCC CACCCGAGAGGACCCGGTACAGCCCCATCCCACCCAGCCACCACCAGCTGACTCTCCCCG ACCCGTCCCACCATGGTCTCCACAGCACTCCCGACAGCCCCGCCAAACCAGAGAAGAATG GGCATGCCAAAGACCACCCCAAGATTGCCAAGATCTTTGAGATCCAGACCATGCCCAATG GCAAAACCCGGACCTCCCTCAAGACCATGAGCCGTAGGAAGCTCTCCCAGCAGAAGGAGA AGAAAGCCACTCAGATGCTCGCCATTGTTCTCGGCGTGTTCATCATCTGCTGGCTGCCCT TCTTCATCACACACATCCTGAACATACACTGTGACTGCAACATCCCGCCTGTCCTGTACA GCGCCTTCACGTGGCTGGGCTATGTCAACAGCGCCGTGAACCCCATCATCTACACCACCT TCAACATTGAGTTCCGCAAGGCCTTCCTGAAGATCCTCCACTGCTGACTCTGCTGCCTGC CCGCACAGCAGCCTGCTTCCCACCTCCCTGCCCAGGCCGGCCAGCCTCACCCTTGCGAAC CGTGAGCAGGAAGGCCTGGGTGGATCGGCCTCCTCTTCACCCCGGCAGGCCCTGCAGTGT TCGCTTGGCTCCATGCTCCTCACTGCCCGCACACCCTCACTCTGCCAGGGCAGTGCTAGT GAGCTGGGCATGGTACCAGCCCTGGGGCTGGGCCCCCCAGCTCAGGGGCAGCTCATAGAG TCCCCCCTCCCACCTCCAGTCCCCCTATCCTTGGCACCAAAGATGCAGCCGCCTTCCTTG ACCTTCCTCTGGGGCTCTAGGGTTGCTGGAGCCTGAGTCAGGGCCCAGAGGCTGAGTTTT CTCTTTGTGGGGCTTGGCGTGGAGCAGGCGGTGGGGAGAGATGGACAGTTCACACCCTGC AAGGCCCACAGGAGGCAAGCAAGCTCTCTTGCCGAGGAGCCAGGCAACTTCAGTCCTGGG AGACCCATGTAAATACCAGACTGCAGGTTGGACCCCAGAGATTCCCAAGCCAAAAACCTT AGCTCCCTCCCGCACCCCGATGTGGACCTCTACTTTCCAGGCTAGTCCGGACCCACCTCA CCCCGTTACAGCTCCCCAAGTGGTTTCCACATGCTCTGAGAAGAGGAGCCCTCATCTTGA AGGGCCCAGGAGGGTCTATGGGGAGAGGAACTCCTTGGCCTAGCCCACCCTGCTGCCTTC TGACGGCCCTGCAATGTATCCCTTCTCACAGCACATGCTGGCCAGCCTGGGGCCTGGCAG GGAGGTCAGGCCCTGGAACTCTATCTGGGCCTGGGCTAGGGGACATCAGAGGTTCTTTGA GGGACTGCCTCTGCCACACTCTGACGCAAAACCACTTTCCTTTTCTATTCCTTCTGGCCT TTCCTCTCTCCTGTTTCCCTTCCCTTCCACTGCCTCTGCCTTAGAGGAGCCCACGGCTAA GAGGCTGCTGAAAACCATCTGGCCTGGCCTGGCCCTGCCCTGAGGAAGGAGGGGAAGCTG CAGCTTGGGAGAGCCCCTGGGGCCTAGACTCTGTAACATCACTATCCATGCACCAAACTA ATAAAACTTTGACGAGTCAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC021195 unedited CACTTTTTTTTGTAAACGATTATATAGGGCGGCCGCGAATTCGCACGAGGGCGGGAGCTG GAACCTCAAGCACCGGCGCCGTCTCTGCCCCGGGGCGCCCTATGGCTTGAAGAGCCTGGC CACCCAGTGGCTCCACCGCCCTGATGGATCCACTGAATCTGTCCTGGTATGATGATGATC TGGAGAGGCAGAACTGGAGCCGGCCCTTCAACGGGTCAGACGGGAAGGCGGACAGACCCC ACTACAACTACTATGCCACACTGCTCACCCTGCTCATCGCTGTCATCGTCTTCGGCAACG TGCTGGTGTGCATGGCTGTGTCCCGCGAGAAGGCGCTGCAGACCACCACCAACTACCTGA TCGTCAGCCTCGCAGTGGCCGACCTCCTCGTCGCCACACTGGTCATGCCCTGGGTTGTCT ACCTGGAGGTGGTAGGTGAGTGGAAATTCAGCAGGATTCACTGTGACATCTTCGTCACTC TGGACGTCATGATGTGCACGGCGAGCATCCTGAACTTGTGTGCCATCAGCATCGACAGGT ACACAGCTGTGGCCATGCCCATGCTGTACAATACGCGCTACAGCTCCAAGCGCCGGGTCA CCGTCATGATCTCCATCGTCTGGGTCCTGTCCTTCACCATCTCCTGCCCACTCCTCTTCG GACTCAATAACGCAGACCAGAACGAGTGCATCATTGCCAACCCGGCCTTCGTGGTCTACT CCTNCATCGTCTCCTTCTACGTGCCCTTCATTGTCACCCTGCTGGTCTACATCAAGATCT ACATTGTCCTNCGCAGACGCCGCAAGCGAGTCAACACCAAACGCAGCAGCCGAGCTTTCA GGGCCCCACCTGAGGCTNCACTAAAGGGGCACTGTACTCACCCCCGAGACATGAACTCTG CACCGTATCATGAAGTCTAATGGGGAGTTTCCATGN
Restriction Sites	Please inquire
ACCN	BC021195
Insert Size	2565 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC021195.2, AAH21195.1
RefSeq Size	2556 bp
RefSeq ORF	1329 bp
Locus ID	1813
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Gap junction, Neuroactive ligand-receptor interaction
Gene Summary	This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]

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